Data for (Study ST002109)
(Analysis AN003451)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 |
|---|---|---|---|---|---|---|
| 2S-5S-Methionine sulfoximine | 1.0869 | 1.9823 | 0.5905 | 2.0320 | 0.7302 | 0.8630 |
| 5-Hydroxyisourate | 0.5010 | 1.5109 | 1.4143 | 1.1561 | 0.6562 | 1.1336 |
| (5-L-Glutamyl)-L-glutamine | 0.6621 | 0.9839 | 0.8451 | 1.2006 | 0.9098 | 1.1698 |
| 5-Oxoproline | 0.7992 | 1.1315 | 0.9790 | 1.1124 | 0.9142 | 1.0753 |
| Acetylcholine | 0.6534 | 1.1011 | 1.1764 | 1.2060 | 0.8834 | 1.0420 |
| acyl-C10:1 (O-Decenoyl-L-carnitine) | 1.2576 | 1.2221 | 0.9218 | 1.0176 | 0.9085 | 1.0054 |
| acyl-C10 (O-Decanoyl-L-carnitine) | 1.2712 | 1.8254 | 0.7884 | 1.2132 | 0.8319 | 0.9308 |
| acyl-C12:1 (O-dodecenoyl-carnitine) | 1.7638 | 1.4236 | 0.7788 | 1.4103 | 0.8080 | 0.8768 |
| acyl-C14:1 (Tetradecenoyl Carnitine) | 1.3169 | 1.6651 | 0.7913 | 1.3948 | 0.8375 | 0.8946 |
| acyl-C14 (O-tetradecanoyl-L-carnitine) | 0.7341 | 1.0820 | 0.8856 | 1.7053 | 0.8454 | 1.0241 |
| acyl-C16 (L-Palmitoylcarnitine) | 0.6596 | 1.3259 | 1.0175 | 1.1308 | 0.8876 | 1.0687 |
| acyl-C18:1 (O-octadecenoyl-L-carnitine) | 0.7083 | 1.3075 | 0.6124 | 1.0706 | 0.8510 | 1.2727 |
| acyl-C18:2 (Linoleoyl-CoA) | 0.4296 | 0.9826 | 0.8754 | 0.8059 | 0.8416 | 1.4017 |
| acyl-C18 (Octadecanoyl-L-carnitine) | 0.4969 | 1.4508 | 1.0738 | 1.2172 | 0.8711 | 1.0457 |
| acyl-C20:4 | 0.4075 | 0.8375 | 0.6525 | 0.9841 | 0.7319 | 1.5809 |
| acyl-C2 (acetyl-carnitine) | 0.9744 | 1.3772 | 1.1211 | 1.2121 | 0.9046 | 0.9024 |
| acyl-C3 (propionyl-carnitine) | 1.1241 | 1.2571 | 0.9563 | 1.8438 | 0.7952 | 0.8741 |
| acyl-C4 (butanoyl-l-carnitine) | 1.1061 | 1.1379 | 0.9716 | 1.1462 | 1.0336 | 0.8760 |
| acyl-C4-DC | 0.9048 | 1.2018 | 1.3455 | 1.4567 | 0.7391 | 0.9629 |
| acyl-C4-OH (Hydroxybutyrylcarnitine) | 1.3644 | 2.1677 | 0.7668 | 1.0811 | 0.8031 | 0.9081 |
| acyl-C5:1 (Tiglylcarnitine) | 1.0035 | 0.1192 | 0.2973 | 1.3761 | 1.4603 | 0.8426 |
| acyl-C5 (isovalerylcarnitine) | 0.7165 | 0.7950 | 1.1865 | 1.5244 | 0.6347 | 1.2450 |
| acyl-C5-OH | 1.0271 | 1.7034 | 1.0097 | 1.4975 | 0.7786 | 0.8960 |
| acyl-C6-DC | 1.0261 | 1.0856 | 1.7733 | 1.0110 | 0.8244 | 0.8490 |
| acyl-C6 (hexanoyl-l-carnitine) | 1.1557 | 1.4473 | 0.8847 | 1.0051 | 0.9835 | 0.9201 |
| acyl-C8:1 (octenoyl-l-carnitine) | 1.5004 | 2.0482 | 0.8493 | 0.7438 | 1.0520 | 0.7274 |
| acyl-C8 (L-octanoylcarnitine | 1.2275 | 1.6832 | 0.8611 | 0.9476 | 0.9773 | 0.8820 |
| Allantoate | 0.8817 | 0.9230 | 0.8164 | 1.2301 | 1.0426 | 1.0022 |
| Anthranilate | 0.5337 | 1.1703 | 1.0518 | 1.7373 | 0.8831 | 0.9384 |
| Bilirubin | 0.5658 | 0.7405 | 1.0316 | 0.6755 | 1.3029 | 0.9449 |
| Choline | 1.1079 | 1.1587 | 1.0486 | 1.1032 | 0.9560 | 0.9320 |
| Creatine | 0.5316 | 0.7638 | 0.9417 | 1.2230 | 0.9481 | 1.1683 |
| Creatinine | 1.2145 | 1.0376 | 1.2340 | 1.3599 | 0.8781 | 0.8630 |
| Dimethylglycine | 1.1234 | 1.3934 | 0.9396 | 1.0022 | 0.8641 | 1.0392 |
| Ectoine | 1.2172 | 1.0194 | 1.2839 | 1.5032 | 0.8769 | 0.8045 |
| gamma-Glutamyl-Se-methylselenocysteine | 0.9277 | 0.8602 | 0.8258 | 1.1777 | 1.0576 | 1.0037 |
| Guanine | 1.0404 | 1.4132 | 0.9754 | 1.5700 | 0.8373 | 0.8921 |
| IMP | 0.2450 | 2.3005 | 0.6465 | 2.7199 | 0.6086 | 0.7379 |
| Indole | 0.7508 | 0.7136 | 0.7663 | 1.0434 | 1.5501 | 0.6500 |
| Indolepyruvate | 0.8674 | 1.2839 | 0.8179 | 1.4937 | 0.8994 | 0.9838 |
| kynurenine | 0.9130 | 1.3876 | 0.9879 | 0.8878 | 1.0657 | 0.9041 |
| L-Adrenaline | 0.9364 | 0.7853 | 0.9299 | 1.2575 | 1.0336 | 0.9784 |
| L-alanine | 1.0699 | 1.3403 | 0.9344 | 1.1693 | 0.8837 | 0.9948 |
| L-arginine | 1.2539 | 0.6588 | 0.4985 | 0.9398 | 1.0733 | 1.1582 |
| L-Carnitine | 0.9070 | 0.8967 | 1.0594 | 1.3618 | 0.9259 | 0.9852 |
| L-cysteine | 0.9397 | 1.2719 | 1.1430 | 1.2289 | 0.8581 | 0.9677 |
| L-cystine | 1.1756 | 1.1861 | 1.6881 | 0.8258 | 0.8731 | 0.8323 |
| L-glutamate | 0.9636 | 1.3509 | 0.8386 | 0.7788 | 0.9088 | 1.1488 |
| L-Homocysteine | 0.3999 | 0.7142 | 1.1112 | 1.5206 | 0.9586 | 1.0428 |
| L-leucine/isoleucine | 0.9760 | 1.4029 | 0.8872 | 1.4377 | 0.8012 | 1.0200 |
| L-lysine | 1.0175 | 1.3729 | 0.8481 | 1.4808 | 0.8012 | 1.0192 |
| L-methionine | 1.0442 | 1.3468 | 1.0023 | 1.5800 | 0.8606 | 0.8698 |
| L-phenylalanine | 1.0741 | 1.3699 | 0.8463 | 1.2446 | 0.8665 | 1.0149 |
| L-proline | 0.7482 | 1.2635 | 0.9496 | 1.2090 | 0.9401 | 1.0123 |
| L-serine | 0.8831 | 1.2151 | 0.9049 | 1.1973 | 0.9165 | 1.0367 |
| L-tryptophan | 0.8266 | 1.2293 | 1.0544 | 1.6872 | 0.8520 | 0.9028 |
| L-tyrosine | 1.0401 | 1.2900 | 0.8827 | 1.3057 | 0.8630 | 1.0119 |
| L-valine | 0.8904 | 1.3089 | 1.0344 | 1.3588 | 0.8500 | 0.9804 |
| N-Acetylornithine | 0.5398 | 0.9917 | 1.1899 | 1.5265 | 1.0213 | 0.8518 |
| N-formyl kynurenine | 0.9875 | 0.4571 | 0.3889 | 1.1494 | 0.7926 | 1.5247 |
| N-Methylethanolamine phosphate | 0.5675 | 1.3275 | 1.6044 | 1.0075 | 0.7129 | 1.0766 |
| Phosphocreatine | 0.5713 | 2.2678 | 0.7532 | 1.5311 | 0.7476 | 0.9474 |
| Phosphoserine | 1.1070 | 0.9090 | 0.6883 | 1.3369 | 0.9937 | 1.0188 |
| S-Glutathionyl-L-cysteine | 0.3683 | 0.7332 | 0.8387 | 1.2541 | 0.8792 | 1.3279 |
| Spermidine | 1.1130 | 0.5768 | 0.5009 | 0.3820 | 1.0058 | 1.4337 |
| Spermine | 1.4192 | 0.3451 | 0.3229 | 0.1843 | 1.6674 | 0.9781 |
| Urate | 0.9741 | 1.1327 | 1.0783 | 1.5626 | 0.8773 | 0.8949 |
Factors:
| F1 | Phenotype:NA | Treatment:Post |
| F2 | Phenotype:NA | Treatment:Pre |
| F3 | Phenotype:non-responder | Treatment:Post |
| F4 | Phenotype:non-responder | Treatment:Pre |
| F5 | Phenotype:Responder | Treatment:Post |
| F6 | Phenotype:Responder | Treatment:Pre |
