Data for (Study ST002121)

(Analysis AN003472)

Values for each metabolite have been scaled by dividing by the mean across all factors

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Metabolite	F1	F2
2,4-Diaminobutyric acid	0.8295	1.1705
2-Aminoimidazole	0.8823	1.1177
2-Deoxyadenosine	0.6390	1.3610
2^-Deoxycytidine 5^-monophosphate	0.9767	1.0233
2-Deoxyguanosine	0.9693	1.0307
2^-Deoxyguanosine 5^-monophosphate	0.6702	1.3298
2^-Deoxyuridine	1.0567	0.9433
2-Methylhippuric acid	0.9226	1.0774
3-Guanidinopropionic acid	0.8992	1.1008
3-Indoleacrylic acid	1.0176	0.9824
3-Isobutyl-1-methylxanthine	0.9675	1.0325
3-Phenylpropionylglycine	1.2292	0.7708
5-Aminolevulinic acid	0.9369	1.0631
5-aminosalicylic acid	0.8811	1.1189
5-Dodecenoic acid	1.0590	0.9410
5-Hydroxy-L-tryptophan	0.9250	1.0750
5-Methylcytidine	1.0940	0.9060
6-Aminocaproic acid	0.9315	1.0685
Acetylcarnitine	0.9271	1.0729
Acetylcholine	0.9078	1.0922
Adenine	0.7679	1.2321
Adenosine	0.8533	1.1467
Adenosine 5^-monophosphate	0.6070	1.3930
Adenylosuccinic acid	0.7092	1.2908
Alanine	0.9443	1.0557
Aminoadipic acid	0.8024	1.1976
Arachidonic acid	1.1647	0.8353
ATP	0.9672	1.0328
Betaine	0.8447	1.1553
Beta-Sitosterol	1.1938	0.8062
Biotin	0.9242	1.0758
cAMP	0.8001	1.1999
Cholesterol	1.0621	0.9379
Choline	0.9354	1.0646
Creatine	0.9421	1.0579
Cyanocobalamin	1.0265	0.9735
Cytidine	0.7957	1.2043
Cytidine monophosphate	0.8242	1.1758
Cytosine	0.9411	1.0589
Daidzein	1.0460	0.9540
Dehydrocholic acid	1.0129	0.9871
Deoxycytidine	0.7594	1.2406
Dopamine	0.8615	1.1385
Ethyl 4-hydroxybenzoate	1.0297	0.9703
Ethylmethylacetic acid	0.8007	1.1993
Eupatorin	0.8680	1.1320
Fmoc-cys(tbu)-OH	0.9921	1.0079
Gamma-Aminobutyric acid	0.7972	1.2028
Glucosamine	0.9231	1.0769
Guanidineacetic acid	1.0087	0.9913
Guanosine 5^-monophosphate	0.6748	1.3252
Hexanoylcarnitine	0.8600	1.1400
Hippuric acid	1.0061	0.9939
Histamine	0.9411	1.0589
Hypoxanthine	0.9182	1.0818
Indole-3-acetic acid	0.8530	1.1470
Indole-3-propionic acid	0.7643	1.2357
Indolepyruvic acid	0.9431	1.0569
Inosine	0.9612	1.0388
Inosine-5^-monophosphate	0.8761	1.1239
Isoleucine	1.0182	0.9818
Isonicotinic acid	0.9038	1.0962
L-Arginine	0.7712	1.2288
L-Asparagine	0.7795	1.2205
L-Aspartic acid	0.8021	1.1979
L-Carnitine hydrochloride	0.8605	1.1395
L-Citrulline	1.0524	0.9476
L-Cysteic acid	0.9468	1.0532
L-Glutamine	1.0055	0.9945
L-Histidine	1.1805	0.8195
L-Homocysteine	0.9903	1.0097
Lipoamide	1.0233	0.9767
L-Kynurenine	1.0216	0.9784
L-Leucine	1.0067	0.9933
L-Lysine	0.9392	1.0608
L-Methionine	1.0534	0.9466
L-Norleucine	0.9821	1.0179
L-Ornithine	1.1207	0.8793
L-Phenylalanine	0.9629	1.0371
L-Proline	0.9739	1.0261
L-Valine	1.0149	0.9851
N-Acetylglutamine	1.0469	0.9531
N-Acetyl-L-cysteine	0.8401	1.1599
N-Acetyl-L-methionine	0.9928	1.0072
Nicotinic acid	0.9038	1.0962
Normetanephrine	0.9489	1.0511
Norvaline	1.0583	0.9417
Oxidized glutathione	0.8862	1.1138
Palmitoyl-l-carnitine	0.9994	1.0006
Pelargonic acid	1.0644	0.9356
Phosphoenolpyruvic acid	1.0280	0.9720
p-Hydroxyphenylpyruvate	0.8299	1.1701
Pipecolic acid	0.8718	1.1282
Putrescine	1.3476	0.6524
Pyridoxal	0.9726	1.0274
Pyridoxal 5^-phosphate	1.0047	0.9953
Pyrogallol	0.9930	1.0070
Pyroglutamic acid	0.8029	1.1971
Reduced glutathione	0.8607	1.1393
S-(5^-Adenosyl)-L-homocysteine	0.9533	1.0467
Salicyluric acid	0.6819	1.3181
Sarcosine	0.9772	1.0228
Serotonin	0.9741	1.0259
Spermidine	0.8752	1.1248
Sphinganine	1.0324	0.9676
Taurohyodeoxycholic acid	0.5125	1.4875
Taurolithocholic acid	0.9341	1.0659
Thiamine	0.9915	1.0085
Thymine	0.9953	1.0047
Trans-4-Hydroxy-L-proline	1.0159	0.9841
Trimethoprim	0.9424	1.0576
Trimethylamine N-oxide	0.7432	1.2568
Tryptamine	1.1708	0.8292
Tryptophan	0.9869	1.0131
Uracil	0.9778	1.0222
Uridine 5^-monophosphate	0.5310	1.4690

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Factors:

F1	Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 0.2ml normal saline
F2	Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 25mg/kg gemcitabine in 0.2ml