Data for (Study ST002152)

(Analysis AN003523)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
13^-Hydroxy-alpha-tocotrienol 0.5033 1.4967
1-Methylnicotinamide 1.0477 0.9523
1-Pyrroline-2-carboxylate/1-Pyrroline-5-carboxylate 0.7627 1.2373
24-Oxo-1alpha-23-25-trihydroxyvitamin D3 0.7410 1.2590
2-Aminoacrylic acid 0.8271 1.1729
2-Deoxyguanosine/Adenosine 0.6508 1.3492
2-Methylbutyrylglycine/Isovalerylglycine 0.9559 1.0441
2-Phenylethanamine 1.0161 0.9839
3,5-dihydroxy-3,4-dihydro-1,4-benzothiazine 0.7911 1.2089
3-Hydroxybutyryl carnitine 1.0324 0.9676
3-Hydroxyhexadecanoyl carnitine 0.5058 1.4942
3-Hydroxyhexadecenoyl carnitine 0.6373 1.3627
3-Hydroxyisovaleryl carnitine 0.8301 1.1699
3-Hydroxy-N6,N6,N6-trimethyl-L-lysine 0.9657 1.0343
3-Methylcrotonoylglycine 1.0248 0.9752
3-Oxo-10-hydroxy-octadeca-6E,8E,12Z-trienoate/3-Oxo-10-hydroxy-octadeca-6E,8E,12Z-trienoate 0.9644 1.0356
3(S)10(R)-OH-octadeca-6-trans-4,1,2-cis-trienoate 0.8773 1.1227
3-Ureidoisobutyrate/Glycylsarcosine 1.0687 0.9313
4-Acetamidobutanal-1 0.9801 1.0199
4-Imidazolone-5-propanoate 0.9698 1.0302
4-Trimethylammoniobutanal 0.9891 1.0109
5,6-dihydrothymine 1.0375 0.9625
5-Amino-1-(5-phospho-ribosyl)imidazole 1.0369 0.9631
5-Guanidino-2-oxopentanoic acid 0.6949 1.3051
5-Hydroxytryptophol/1,2-dehydrosalsolinol/N,N-dimethylindoliumolate-1 0.9008 1.0992
5-Methylthioadenosine 0.9284 1.0716
Acetamidopropanal 0.7419 1.2581
Acetyl carnitine 0.9540 1.0460
Acetylcholine/4-(Trimethylammonio)butanoate 0.6842 1.3158
Adenine 0.9935 1.0065
ADP 1.0314 0.9686
Alanine 0.8826 1.1174
Alanyl-alanine 0.9096 1.0904
Alanyl-leucine 0.8537 1.1463
Alpha-linolenyl carnitine/gamma-linolenyl carnitine 0.7377 1.2623
Anthranilate 0.8451 1.1549
Asparagine 0.8756 1.1244
ATP 1.0769 0.9231
Benzoate 0.7851 1.2149
Butyryl carnitine 1.0132 0.9868
C10H16O(3) 0.9175 1.0825
C18H32O4(3) 0.9748 1.0252
C20H28O2(7) 0.8170 1.1830
C20H28O(5) 0.8728 1.1272
C27H42O4(3) 1.0729 0.9271
C27H44O2(5) 1.1919 0.8081
C27H44O3(5) 1.0438 0.9562
C27H46O3(6) 1.1061 0.8939
C4H9NO2(4) 0.8635 1.1365
C6H11NO3(4) 1.0280 0.9720
C9H13N5O3(4) 0.8717 1.1283
C9H8O3(3) 0.7797 1.2203
Carnitine 0.8951 1.1049
CDP choline 0.8694 1.1306
CDP-ethanolamine 0.9751 1.0249
Choline 0.8974 1.1026
Choline phosphate 0.8551 1.1449
Citr_L[e] 0.6756 1.3244
CMP-N-acetyl-beta-neuraminate 0.9415 1.0585
Coenzyme A 0.9832 1.0168
Coumarin 0.7686 1.2314
Creatine 0.9585 1.0415
Creatinine 0.8784 1.1216
Cystathionine 0.6594 1.3406
Cysteinylglycine 1.0153 0.9847
Cytosine 0.9773 1.0227
Decanoyl carnitine 1.2358 0.7642
Decenoyl carnitine 0.9403 1.0597
Dopaminochrome 0.8207 1.1793
Elaidic carnitine/Vaccenyl carnitine 1.0700 0.9300
Flavin adenine dinucleotide oxidized 0.9886 1.0114
Gamma-glutamyl-alanine/Glutamyl-alanine-1 0.9616 1.0384
Glucosamine 0.9654 1.0346
Glutamine 1.0687 0.9313
Glutaryl carnitine 0.9826 1.0174
Glutathionate 1.0110 0.9890
Glycine betaine 0.9832 1.0168
Glycylleucine 0.7701 1.2299
Glycylproline/Prolinylglycine 0.8791 1.1209
GSSG 0.9387 1.0613
Guanine 0.9212 1.0788
Heptadecanoyl carnitine 1.1362 0.8638
Histamine 0.4129 1.5871
Histidine 1.0322 0.9678
Hypoxanthine 0.7869 1.2131
Imidazole-4-acetaldehyde 1.0599 0.9401
Isoputreanine/Putreanine 0.8222 1.1778
Kynurenine/Formyl-5-hydroxykynurenamine 0.8054 1.1946
Limonene/Alpha-pinene 0.9637 1.0363
Linoleyl carnitine/Linoelaidyl carnitine 0.9790 1.0210
Lysyl-proline 0.8063 1.1937
Methionine 0.8606 1.1394
Methylimidazoleacetic acid 0.7383 1.2617
Methyl indole-3-acetate 0.9367 1.0633
Mevalonate 1.0709 0.9291
N1,N12-diacetylspermidine 0.8967 1.1033
N(2)-acetyl-ornithine 0.8838 1.1162
N6,N6,N6-trimethyl-L-lysine 1.0188 0.9812
N(8)-acetylspermidine/N(1)-acetylspermidine 1.3154 0.6846
N-acetyl-asparagine 0.5307 1.4693
N-acetyl-glucosamine 0.8736 1.1264
N-acetylneuraminic acid 0.7606 1.2394
N-acetylputrescine 1.0694 0.9306
NAD+ 1.1098 0.8902
NADP+ 1.0908 0.9092
NeuNGc 0.8488 1.1512
Nicotinamide 0.9261 1.0739
N-Methylethanolamine phosphate 0.9818 1.0182
N,N-dimethylglycine 0.7978 1.2022
N-ribosylnicotinamide 0.9982 1.0018
Octanoyl carnitine 1.2797 0.7203
Octenoyl carnitine 1.0578 0.9422
Ornithine 0.6029 1.3971
Palmitoyl carnitine 1.1006 0.8994
Pendtadenoyl carnitine 1.0520 0.9480
Perillyl aldehyde 0.9420 1.0580
Phenylacetaldehyde 0.7672 1.2328
Phenylalanine 0.9620 1.0380
Phosphodimethylethanolamine 0.9475 1.0525
Pipecolic acid-2 0.7886 1.2114
Proline 0.7419 1.2581
Propionyl carnitine 0.6922 1.3078
Pseudoecgonine/Ecgonine 0.9696 1.0304
Pyridoxal 0.8418 1.1582
Riboflavin 0.8339 1.1661
S-(2-Methylpropanoyl)-dihydrolipoamide 0.7382 1.2618
S-Adenosyl-L-homocysteine 0.8798 1.1202
S-adenosyl-L-methionine 0.9816 1.0184
Salsolinol/N,N-dimethyldopaminequinone-1 0.9370 1.0630
Serine 0.8660 1.1340
Serotonin 0.9958 1.0042
sn-Glycero-3-phosphocholine 1.0639 0.9361
Spermidine 1.0248 0.9752
Spermidine dialdehyde-1 0.9046 1.0954
Spermidine dialdehyde-2 0.9756 1.0244
Sphingosine/1-Hydroxy-3-oxooctadecan-2-aminium 1.0772 0.9228
Stearoyl carnitine 1.1712 0.8288
Succinyl carnitine 0.9812 1.0188
Tetradecanoyl carnitine(myristoyl carnitine) 1.0508 0.9492
Tetradecenoyl carnitine 1.1342 0.8658
Thiamine 0.8627 1.1373
Threonine 0.8123 1.1877
Thymine/Imidazol-4-ylacetate 0.9607 1.0393
Tiglyl carnitine 0.8077 1.1923
Trans-hexadec-2-enoyl carnitine 1.0199 0.9801
Tyramine 0.9667 1.0333
Tyrosine 0.7807 1.2193
UDP 1.1669 0.8331
Ureidopropionic acid/Glycyl-glycine 0.8764 1.1236
Urocanate 0.9126 1.0874
Valine 0.9942 1.0058
Xanthosine 0.6114 1.3886
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Factors:

F1Sample Source:SIRT5 knockout
F2Sample Source:Wild type
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