Data for (Study ST002153)
(Analysis AN003526)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 10-Hydroxydecanoic acid | 0.9467 | 1.2585 | 1.0431 | 0.8163 |
| 11-Aminoundecanoic acid | 1.0645 | 0.9462 | 1.0538 | 0.9355 |
| 1H-Imidazole-4-propionic acid | 1.3572 | 0.6273 | 1.5282 | 0.4873 |
| 1-Methyl-4-imidazoleacetic acid | 1.0071 | 1.0353 | 1.0071 | 0.9505 |
| 1-Methyladenosine | 1.0423 | 0.8360 | 0.9206 | 1.2011 |
| 1-Methylhistamine | 0.8288 | 1.3514 | 1.0518 | 0.7680 |
| "1-Methylhydantoin Glycine anhydride" | 1.0169 | 1.0791 | 1.1073 | 0.7966 |
| 1-Methylnicotinamide | 0.6518 | 1.2603 | 0.8392 | 1.2487 |
| 1-Methyluric acid | 1.0404 | 0.7844 | 1.2054 | 0.9672 |
| 2,3-Diphosphoglyceric acid | 0.7537 | 0.8827 | 1.2969 | 1.0667 |
| 2,5-Dihydroxybenzoic acid | 1.1255 | 0.8450 | 1.0314 | 0.9963 |
| 2,6-Diaminopimelic acid | 1.4993 | 0.9374 | 1.0143 | 0.5489 |
| 2-Amino-2-(hydroxymethyl)-1,3-propanediol | 0.8898 | 0.7373 | 1.2797 | 1.0932 |
| "2-Aminoadipic acid O-Acetylhomoserine" | 1.0163 | 0.9251 | 1.1700 | 0.8886 |
| "2-Aminobutyric acid 2-Aminoisobutyric acid" | 1.0551 | 0.9486 | 1.1422 | 0.8542 |
| 2-(Creatinine-3-yl)propionic acid | 0.8806 | 1.5311 | 0.5944 | 0.8568 |
| "2^-Deoxyadenosine 5^-Deoxyadenosine" | 0.5751 | NA | 1.4249 | NA |
| 2^-Deoxycytidine | 1.0164 | 1.0000 | 0.9016 | 1.0820 |
| 2^-Deoxyuridine | 0.5357 | 0.6840 | 1.2652 | 1.6869 |
| 2-Hydroxy-4-methylvaleric acid | 1.1593 | 0.7805 | 1.0187 | 1.0416 |
| 2-Hydroxybutyric acid | 1.0732 | 0.7102 | 1.4829 | 0.7337 |
| 2-Hydroxyoctanoic acid | 0.9365 | 0.8308 | 1.1734 | 1.1820 |
| 2-Hydroxyvaleric acid | 1.2442 | 0.7880 | 1.0369 | 0.9309 |
| 2-Isopropylmalic acid | NA | NA | 1.0000 | NA |
| 2-Methylserine | 1.0298 | 0.8170 | 1.0809 | 1.0723 |
| 2-Oxoglutaric acid | 1.4350 | 0.5869 | 1.3316 | 0.6464 |
| 2-Oxoisovaleric acid | 1.0646 | 1.0543 | 0.8165 | 1.0646 |
| "3-(4-Hydroxyphenyl)propionic acid 3-(3-Hydroxyphenyl)propionic acid 2-(4-Hydroxyphenyl)propionic acid" | 1.0350 | 0.9628 | 0.9929 | NA |
| 3-Amino-2-piperidone | 1.1230 | 1.0873 | 0.9804 | 0.8093 |
| 3-Aminobutyric acid | 1.0902 | 1.0710 | 0.7459 | 0.9754 |
| 3-Guanidinopropionic acid | 1.0759 | 0.5379 | 1.3168 | 0.7845 |
| 3-Hydroxy-2-methyl-4-pyrone | 1.1536 | 0.8839 | 1.0037 | 0.9588 |
| 3-Hydroxy-3-methylglutaric acid | 1.1397 | 0.6116 | 1.3241 | 0.8276 |
| 3-Hydroxybutyric acid | 1.0174 | 0.9302 | 1.0407 | 1.0116 |
| 3-Hydroxykynurenine | 1.1904 | 0.9472 | 1.0496 | 0.8128 |
| 3-Indoxylsulfuric acid | 1.0851 | 0.7534 | 1.3440 | 0.8175 |
| 3-Methoxytyrosine | 1.1384 | 0.8811 | 0.9201 | 1.0604 |
| 3-Methyladenine | 0.8162 | 0.6880 | 1.4762 | 1.0261 |
| 3-Methylhistamine | 0.8218 | 1.2593 | 1.1793 | 0.7396 |
| "3-Methylhistidine 1-Methylhistidine" | 1.0795 | 1.0879 | 0.7782 | 1.0544 |
| 3-Phenylpropionic acid | 1.5161 | 1.1426 | 0.9485 | 0.3928 |
| 3-Phosphoglyceric acid | 0.9490 | 1.1847 | 0.9697 | 0.8838 |
| 3-Ureidopropionic acid | 0.8901 | 0.8681 | 1.3407 | 0.9011 |
| 4-Acetamidobutanoic acid | 1.1988 | 0.2488 | 1.9658 | 0.5865 |
| 4-Aminohippuric acid | 1.3065 | 0.4859 | 1.0780 | 1.1295 |
| 4-Guanidinobutyric acid | 1.1331 | 0.4336 | 1.7295 | 0.7037 |
| 4-Hydroxy-3-methoxyphenylglycol sulfate | 0.8775 | 0.8324 | 1.2257 | 1.0790 |
| "4-Methyl-2-oxovaleric acid 3-Methyl-2-oxovaleric acid 2-Oxohexanoic acid" | 1.0411 | 1.1329 | 0.8513 | 0.9747 |
| 4-Methyl-5-thiazoleethanol | 1.4426 | 1.2125 | 0.8969 | 0.4222 |
| 4-Oxopyrrolidine-2-carboxylic acid | 1.2018 | 1.2047 | 0.9444 | 0.6491 |
| 4-Pyridoxic acid | 0.9926 | 0.8088 | 1.4338 | 0.7169 |
| 4-(β-Acetylaminoethyl)imidazole | 0.5506 | 0.7147 | 1.5035 | 0.5029 |
| 5-Amino-4-oxovaleric acid | 1.1680 | 0.7649 | 1.1680 | 0.8992 |
| 5-Aminoindole | 1.2133 | 1.0267 | 0.2800 | NA |
| 5-Aminovaleric acid | NA | NA | 1.0000 | NA |
| 5^-Deoxy-5^-methylthioadenosine | 1.0845 | 0.8838 | 1.1268 | 0.9049 |
| 5-Hydroxyindoleacetic acid | NA | 0.8706 | 1.0543 | 1.1022 |
| 5-Hydroxylysine | 0.9655 | 1.1310 | 1.0207 | 0.8828 |
| 5-Hydroxypentanoic acid | 1.0037 | 0.8473 | 1.1862 | 0.5866 |
| "5-Methoxyindoleacetic acid Indole-3-lactic acid" | 1.0195 | 0.9467 | 1.2094 | 0.8244 |
| 5-Methyl-2^-deoxycytidine | 0.9353 | 0.9784 | 0.8777 | 1.2086 |
| 5-Methylcytosine | 0.6153 | 0.6208 | 1.8293 | 0.8398 |
| 5-Oxoproline | 1.0792 | 1.0450 | 1.0878 | 0.7880 |
| 6-Aminohexanoic acid | 0.8989 | 0.7814 | 1.2493 | 1.0312 |
| 6-Hydroxyhexanoic acid | 1.0093 | 1.2007 | 1.0209 | 0.7744 |
| 6-Phosphogluconic acid | NA | NA | 1.0268 | 0.9464 |
| 7,8-Dihydrobiopterin | 1.0892 | 0.8576 | 1.1768 | 0.8764 |
| 7-Methylguanine | 0.9910 | 0.9189 | 0.9910 | 1.0991 |
| 8-Hydroxyoctanoic acid | 0.9829 | 1.2113 | 0.9978 | 0.8608 |
| Acetoacetamide | 1.0140 | 1.0140 | 0.9628 | 1.0093 |
| Acetoacetic acid | 0.9674 | 1.0482 | 0.9382 | 1.0547 |
| Adenosine | 0.9262 | 0.6736 | 1.6256 | 0.6930 |
| Adipic acid | NA | NA | 1.0000 | NA |
| ADMA | 1.0514 | 1.1581 | 0.7848 | 1.0057 |
| ADP | 0.7727 | 1.0873 | 1.4413 | 0.6987 |
| ADP-ribose | 0.5821 | NA | 1.3628 | 0.8462 |
| Adrenaline | NA | NA | 1.1316 | 0.4735 |
| Ala | 1.0909 | 1.2452 | 0.7934 | 0.8705 |
| Albizziine | 0.3890 | 2.5787 | NA | 0.6774 |
| Allantoic acid | 1.2458 | 0.9767 | 0.9568 | 0.6179 |
| Allantoin | 1.1741 | 1.0249 | 0.7861 | 1.0149 |
| AMP | 0.7698 | 1.0291 | 1.5503 | 0.6508 |
| Anserine_divalent | 1.1814 | 1.2152 | 0.8439 | 0.7595 |
| Anthranilic acid | 1.1020 | NA | 0.9796 | 0.8571 |
| Arg | 0.9412 | 1.2583 | 0.8696 | 0.9309 |
| Argininosuccinic acid | 1.1265 | 0.8968 | 1.0582 | 0.9185 |
| Ascorbate 2-phosphate | 1.1755 | NA | 0.9639 | 0.9483 |
| Ascorbate 2-sulfate | 0.9412 | 1.1765 | 0.7421 | 1.1403 |
| Asn | 1.1986 | 1.3093 | 0.7461 | 0.7461 |
| Asp | 1.1789 | 1.4580 | 0.7724 | 0.5908 |
| ATP | 0.8818 | 1.0362 | 1.2465 | 0.8355 |
| Azelaic acid | 1.1122 | 0.8163 | 1.0612 | 0.9524 |
| Azetidine 2-carboxylic acid | NA | NA | 1.0000 | NA |
| Betaine | 1.1116 | 1.2756 | 0.8200 | 0.7927 |
| Betonicine | 1.1141 | 1.1594 | 0.7850 | 0.8877 |
| Biopterin | 1.0049 | 0.9693 | 1.0111 | 1.0197 |
| "Butyric acid Isobutyric acid" | 0.9571 | 1.0232 | 1.0418 | NA |
| Butyrylcarnitine | 1.1542 | 0.4567 | 1.7148 | 0.6744 |
| cAMP | 1.0529 | 1.4670 | 0.5220 | 0.6432 |
| Carboxymethyllysine | 1.2477 | 0.9457 | 1.0256 | 0.7810 |
| Carnitine | 1.1034 | 1.1207 | 0.9138 | 0.8621 |
| Carnosine | 1.1187 | 1.2582 | 0.8585 | 0.7646 |
| Cholic acid | 1.4078 | 1.2950 | 1.1783 | 0.1189 |
| Choline | 1.1498 | 0.7682 | 1.0618 | 1.0202 |
| cis-Aconitic acid | 1.2550 | 0.8606 | 1.0956 | 0.7888 |
| Citric acid | 1.2247 | 0.8494 | 1.0765 | 0.8494 |
| Citrulline | 1.1044 | 1.0425 | 0.8702 | 0.9829 |
| CMP | NA | NA | 1.0000 | NA |
| CMP-N-acetylneuraminate | 1.1293 | 0.1997 | 1.7180 | 0.7529 |
| Creatine | 1.1716 | 1.1866 | 0.7761 | 0.8657 |
| Creatinine | 1.1625 | 1.0069 | 0.9336 | 0.8970 |
| Cys | 1.1458 | 1.7708 | 0.4514 | 1.2917 |
| Cystathionine | 1.1563 | 0.8822 | 0.8822 | 1.0792 |
| Cysteine glutathione disulfide | 1.1607 | 0.5087 | 1.2423 | 1.0882 |
| Cystine | 0.9174 | 1.4035 | 0.6456 | 1.0335 |
| Cytidine | 1.1629 | 0.8251 | 1.0105 | 1.0015 |
| Decarboxylated S-Adenosylmethionine | 1.3245 | 0.3495 | 1.3543 | 0.7548 |
| dGDP | 1.3191 | 0.9208 | 0.7923 | 0.9679 |
| Diethanolamine | 1.4434 | 1.1302 | 0.7196 | 0.7069 |
| Dihydroorotic acid | NA | NA | 1.0000 | NA |
| Dihydroxyacetone phosphate | 1.1875 | 0.9000 | 1.0833 | 0.7000 |
| Dodecanedioic acid | 0.8152 | 1.2571 | 1.1486 | NA |
| Ectoine | 0.9826 | 1.1047 | 0.8605 | 1.0523 |
| Ergothioneine | 0.2563 | 3.0937 | 1.0297 | 0.3047 |
| Ethanolamine | 1.2272 | 1.2106 | 0.7662 | 0.7960 |
| Ethanolamine phosphate | 0.9279 | 1.5672 | 0.7786 | 0.7264 |
| Ethionine | NA | 1.0000 | NA | NA |
| Ethyl glucuronide | 0.9780 | 1.1024 | 1.0585 | 0.8610 |
| FAD_divalent | 0.8781 | 1.0507 | 1.1003 | 0.9709 |
| Ferulic acid | 0.9063 | 0.6728 | 1.4348 | 1.2435 |
| Formiminoglutamic acid | 1.0335 | 0.9904 | 1.2165 | 0.8397 |
| Formylanthranilic acid | 0.9671 | 0.8662 | 1.2676 | 0.9155 |
| Fructose 6-phosphate | 1.0641 | 0.8939 | 1.2238 | 0.7577 |
| Fumaric acid | 1.0000 | 0.8333 | 1.0556 | NA |
| Galacturonic acid | 0.9538 | 0.7688 | 1.4624 | 0.8150 |
| GDP | 0.7492 | 0.8789 | 1.3569 | 0.8971 |
| Gibberellic acid | NA | NA | 1.0000 | NA |
| Gln | 1.1893 | 1.0333 | 0.8741 | 0.9033 |
| Glu | 1.3105 | 1.1552 | 0.9639 | 0.5704 |
| Glucaric acid | 0.9219 | 0.9812 | 1.0801 | 1.0168 |
| Gluconic acid | 1.0078 | 0.6130 | 1.5688 | 0.8104 |
| Gluconolactone | 1.0478 | 0.5734 | 1.5290 | 0.8498 |
| "Glucosamine Galactosamine" | 1.0687 | 1.0483 | 0.9669 | 0.9160 |
| Glucosaminic acid | 1.1772 | 1.0058 | 1.2219 | 0.7003 |
| Glucose 1-phosphate | 1.0535 | 0.8176 | 1.3129 | 0.7547 |
| Glucose 6-phosphate | 0.9552 | 0.8229 | 1.4254 | 0.7965 |
| Glucuronic acid | 1.0702 | 0.7227 | 1.2370 | 0.9701 |
| Glutathione (GSH) | 1.1169 | 0.1184 | 1.1416 | 1.4354 |
| Glutathione (GSSG)_divalent | 1.3292 | 0.1821 | 1.7817 | 0.7070 |
| Gly | 1.1359 | 1.2840 | 0.7537 | 0.8264 |
| Gly-Asp | 1.1860 | 0.8837 | 1.0233 | 0.9070 |
| Glyceric acid | 1.0884 | 1.0204 | 1.0068 | 0.8844 |
| Glycerol | 1.2318 | 0.9827 | 0.7474 | 1.0381 |
| Glycerol 3-phosphate | 1.0145 | 1.0040 | 1.0885 | 0.8930 |
| Glycerophosphocholine | 0.9578 | 1.0219 | 0.9300 | 1.0903 |
| Glycocholic acid | 0.8235 | 1.1849 | 1.1597 | NA |
| Glycolic acid | 1.0102 | 0.9594 | 1.0863 | 0.9442 |
| Gly-Gly | 1.1014 | 0.8995 | 0.9711 | 1.0280 |
| Glyoxylic acid | 1.0000 | 0.9060 | 1.0641 | 1.0128 |
| GMP | 0.6070 | 0.7695 | 2.0137 | 0.7265 |
| GTP | 0.5654 | 0.8784 | 1.2924 | 1.9130 |
| Guanidinosuccinic acid | 0.9904 | 0.9726 | 0.9133 | 1.1238 |
| Guanidoacetic acid | 0.9906 | 1.4221 | 0.8780 | 0.7092 |
| Guanine | 1.9251 | NA | 0.5374 | NA |
| Hexamine | 1.8293 | 0.8049 | NA | 0.3659 |
| Hippuric acid | 1.1901 | 0.6182 | 1.4298 | 0.7620 |
| His | 1.1429 | 1.1163 | 0.9037 | 0.8372 |
| His-Glu | 0.9660 | 1.1097 | 1.0106 | 0.6837 |
| Histamine | 0.7330 | 1.2538 | 0.9283 | 1.0850 |
| Homoarginine | 0.8307 | 1.1576 | 0.9441 | 1.0676 |
| Homocarnosine | 1.1849 | 1.1916 | 0.8803 | 0.7431 |
| Homocitrulline | 1.1815 | 1.2677 | 0.7262 | 0.8246 |
| Homocystine | 0.9982 | 0.8262 | 0.9815 | 1.2893 |
| Homoserine | 1.0280 | 1.0748 | 1.0187 | 0.8785 |
| Homoserinelactone | NA | NA | 0.9028 | 1.0324 |
| "Homovanillic acid 3,4-Dihydroxyhydrocinnamic acid Hydroxyphenyllactic acid" | 1.1832 | 0.6022 | 1.3349 | 0.8798 |
| Hydroxyindole | 1.5014 | 0.8540 | 1.1501 | 0.4945 |
| Hydroxyproline | 0.9892 | 1.1800 | 0.8590 | 0.9718 |
| Hypotaurine | 1.3365 | 0.5403 | 1.6493 | 0.4739 |
| Hypoxanthine | 1.0000 | NA | NA | NA |
| Ile | 1.1032 | 1.0491 | 0.9137 | 0.9340 |
| Imidazole-4-acetic acid | 1.2378 | 0.9381 | 1.0033 | 0.8208 |
| Imidazolelactic acid | 1.4836 | 0.4897 | 0.9939 | 1.0327 |
| IMP | 1.0294 | 1.0481 | 0.5802 | 1.2166 |
| Indole-3-acetic acid | 1.0946 | 1.0427 | 1.0946 | 0.6908 |
| Indole-3-carboxylic acid | 0.9676 | 1.5019 | 1.2709 | 0.7856 |
| Indole-3-propionic acid | 1.1881 | 0.8073 | 1.2661 | 0.7385 |
| Inosine | 1.4644 | NA | 0.5774 | 0.4519 |
| Isatin | NA | NA | 1.0000 | NA |
| Isethionic acid | 1.1435 | 1.1785 | 0.7974 | 0.8806 |
| Isobutyrylcarnitine | 1.1683 | 0.4633 | 1.5895 | 0.7789 |
| Isocitric acid | 1.1933 | 0.8739 | 1.1429 | 0.7899 |
| Isoglutamic acid | 0.6561 | 1.2228 | 1.0864 | 0.8466 |
| "Isovaleric acid Valeric acid DL-2-Methylbutyric acid" | NA | 1.0000 | NA | NA |
| Isovalerylalanine | 1.1589 | 0.7975 | 1.0997 | 0.9439 |
| Isovalerylcarnitine | 1.1360 | 0.7471 | 1.4637 | 0.6532 |
| Kynurenic acid | 1.0629 | 0.8288 | 1.4351 | 0.5382 |
| Kynurenine | 1.0607 | 0.9636 | 0.9428 | 1.0329 |
| Lactic acid | 1.0503 | 0.7474 | 1.2166 | 0.9857 |
| Lauric acid | 0.9908 | 1.0435 | 1.0224 | 0.9433 |
| Lauroylcarnitine | 1.0217 | 0.7121 | 1.1641 | 1.1022 |
| Leu | 1.0961 | 1.0162 | 0.9172 | 0.9705 |
| Lipoamide | 0.3486 | 1.7109 | 0.6332 | 1.1445 |
| Lys | 1.0234 | 1.2308 | 0.7759 | 0.9699 |
| Malic acid | 1.3036 | 0.6680 | 1.2915 | 0.7368 |
| Malonylcarnitine | 0.9724 | 1.3067 | 0.9800 | 0.7567 |
| Mannosamine | NA | 0.9484 | NA | 1.1031 |
| Met | 0.9722 | 1.1667 | 0.8889 | 0.9722 |
| Metanephrine | 0.6266 | 0.7405 | 1.3956 | 0.8274 |
| Methionine sulfoxide | 1.0273 | 1.1215 | 0.8903 | 0.9609 |
| Methylguanidine | 1.2400 | NA | 1.0066 | 0.6368 |
| Methyl sulfate | NA | 1.0000 | NA | NA |
| Mevalonic acid | 1.2466 | 1.0004 | 0.9373 | 0.8157 |
| Mucic acid | 1.2389 | 1.0287 | 0.7864 | 0.3858 |
| Muscimol | 1.0398 | 1.0398 | 1.0186 | 0.9019 |
| "myo-Inositol 1-phosphate myo-Inositol 3-phosphate" | 0.8249 | 1.3386 | 0.7164 | 1.0492 |
| Myristoleic acid | 1.2174 | 0.9928 | 0.9783 | 0.8116 |
| N-(1-Deoxy-1-fructosyl)valine | 1.3375 | 0.9288 | 0.9783 | 0.7554 |
| N1-Methyl-4-pyridone-5-carboxamide | 0.7028 | 1.2486 | 0.6131 | 1.4355 |
| N1-Methylguanosine | 0.9506 | 0.8163 | 1.0411 | 1.1920 |
| N2-Acetylaminoadipic acid | NA | NA | 1.0000 | NA |
| N6-Acetyllysine | 1.0563 | 1.0823 | 0.9524 | 0.9091 |
| N6-Methyl-2^-deoxyadenosine | 1.3314 | 1.0533 | 0.5680 | 0.9024 |
| N6-Methyllysine | 0.9125 | 1.2202 | 0.8806 | 0.9867 |
| N6,N6,N6-Trimethyllysine | 1.0904 | 1.0181 | 0.9664 | 0.9251 |
| N8-Acetylspermidine | 0.9856 | 1.1072 | 0.9152 | 0.9920 |
| N-Acetylalanine | 1.0656 | 0.9692 | 0.9531 | 1.0120 |
| N-Acetylasparagine | 1.2757 | 0.8239 | 1.0897 | 0.8106 |
| N-Acetylaspartic acid | 0.9788 | 0.8092 | 1.2100 | 1.0019 |
| N-Acetylglucosamine 1-phosphate | 0.9269 | 1.2600 | 1.0949 | 0.7183 |
| "N-Acetylglucosamine N-Acetylmannosamine N-Acetylgalactosamine" | 1.0709 | 0.9291 | 0.9606 | 1.0394 |
| N-Acetylglucosylamine | 0.9829 | 0.8811 | 1.2059 | 0.9003 |
| N-Acetylglutamic acid | 0.9861 | 0.6877 | 1.3603 | 0.9659 |
| N-Acetylglutamine | 1.2206 | 0.5693 | 0.9978 | 1.1046 |
| N-Acetylglycine | 1.0577 | 0.9038 | 0.9442 | 1.0942 |
| N-Acetylhistidine | 1.0992 | 0.8397 | 1.0229 | 1.0382 |
| N-Acetylleucine | 1.1697 | 0.2443 | 1.6411 | 0.9266 |
| N-Acetyllysine | 1.2219 | 0.7781 | 1.1593 | 0.8407 |
| N-Acetylmethionine | 1.0661 | 0.6615 | 1.2140 | 1.0584 |
| N-Acetylmuramic acid | 1.1335 | 1.3302 | 0.7596 | 0.8868 |
| N-Acetylneuraminic acid | 0.9694 | 1.0353 | 0.9318 | 1.0635 |
| N-Acetylornithine | 1.1828 | 0.7472 | 1.2528 | 0.8172 |
| N-Acetylphenylalanine | 1.3081 | 0.5682 | 1.4512 | 0.6725 |
| N-Acetylputrescine | 1.2594 | 0.8086 | 0.9660 | 0.9660 |
| N-Acetylserine | 1.0957 | 0.8928 | 1.0551 | 0.9565 |
| N-Acetyltryptophan | 1.2154 | 0.7950 | 1.0905 | 0.8991 |
| N-Acetyltyrosine | 1.3492 | 0.9710 | 0.9853 | 0.6945 |
| N-Acetyl-β-alanine | 1.1232 | 0.8473 | 1.1232 | 0.9064 |
| Nalidixic acid | 1.2871 | 0.3967 | 1.1019 | 0.4364 |
| N-Ethylmaleimide_+H2O | 1.0219 | 0.8000 | 1.2047 | 0.9234 |
| N’-Formylkynurenine | 1.1051 | 1.4735 | 0.6120 | 0.8093 |
| N-Formylmethionine | 1.0021 | 0.4571 | 1.3924 | 1.0127 |
| N-Glycolylneuraminic acid | 0.9689 | 1.2008 | 1.0269 | 0.8033 |
| Nicotinamide | 0.7671 | 1.1373 | 0.9558 | 1.1397 |
| N-Methylproline | 1.0250 | 1.0864 | 1.0365 | 0.8522 |
| N,N-Dimethylglycine | 1.0395 | 1.0263 | 0.9605 | 0.9737 |
| "Noradrenaline 6-Hydroxydopamine" | 0.9208 | 0.9310 | 1.0927 | 1.0436 |
| Nω-Methylarginine | 0.9562 | 1.2705 | 0.8437 | 0.9297 |
| O-Acetylcarnitine | 1.1717 | 1.0236 | 0.9697 | 0.8350 |
| Octanoylcarnitine | 0.9713 | 0.6373 | 1.5166 | 0.6935 |
| Octopine | 1.0000 | NA | NA | NA |
| o-Hydroxybenzoic acid | 0.8763 | 0.8418 | 1.2640 | 1.0357 |
| Ophthalmic acid | 1.2008 | 0.2081 | 2.0636 | 0.5275 |
| Ornithine | 1.0805 | 1.1442 | 0.9275 | 0.8478 |
| Orotic acid | 1.3317 | 0.8347 | 1.1001 | 0.7334 |
| Orotidine | 1.2220 | 0.9391 | 0.9571 | 0.7494 |
| O-Sulfoserine | 0.9817 | 1.0102 | 1.1192 | 0.8916 |
| Pantothenic acid | 0.9770 | 1.2069 | 0.8621 | 0.9540 |
| Pargyline | 0.7231 | 1.1590 | 0.7487 | 1.5538 |
| Perillic acid | 1.0556 | 1.0322 | 0.9444 | 0.9678 |
| Phe | 1.1404 | 1.0281 | 0.9607 | 0.8708 |
| "Phenaceturic acid N-(o-Toluoyl)glycine" | 0.8638 | 0.4298 | 0.6491 | 2.0573 |
| Phenol | 1.0482 | 0.9889 | 1.0878 | 0.9262 |
| Phosphocreatine | 0.9138 | 1.5391 | 0.7295 | 0.8176 |
| Phosphorylcholine | 0.8395 | 1.0812 | 1.0552 | 1.0240 |
| Phthalic acid | NA | NA | NA | 1.0000 |
| "p-Hydroxymandelic acid Homogentisic acid" | 1.1184 | 0.8947 | 0.9767 | 1.2675 |
| p-Hydroxyphenylpyruvic acid | 1.1238 | 0.6467 | 1.1593 | 0.9819 |
| Picolinic acid | 1.0033 | 1.0166 | 0.9050 | 1.1602 |
| Pipecolic acid | 1.1558 | 0.9351 | 0.9870 | 0.9221 |
| Piperidine | 0.8803 | NA | 1.1549 | 0.6197 |
| Pro | 1.1088 | 1.2124 | 0.8290 | 0.8497 |
| Propionic acid | 1.1642 | 0.7761 | 0.8955 | NA |
| Prostaglandin E2 | NA | 0.4450 | 1.2047 | 1.6279 |
| Putrescine | 1.0203 | 0.9043 | 1.1942 | 0.8812 |
| Pyridoxal | 0.9611 | 1.2014 | 0.9283 | 0.9092 |
| Pyridoxamine | 1.1759 | 1.1413 | 1.1413 | 0.6294 |
| Pyridoxine | 1.0277 | 0.6727 | 1.2457 | 0.9311 |
| Pyruvic acid | 1.1985 | 0.8698 | 1.1429 | 0.7889 |
| Quinolinic acid | 1.0694 | 0.7792 | 1.2566 | 0.8836 |
| Retinoic acid | 0.7747 | 0.9684 | 1.5632 | 0.3874 |
| Riboflavin | 0.9659 | 1.0321 | 1.0982 | 0.9037 |
| Ribose 5-phosphate | 1.0613 | 0.8010 | 1.3617 | 0.7669 |
| Ribulose 5-phosphate | 1.3146 | 0.5619 | 1.5096 | 0.6139 |
| Saccharopine | 1.4195 | 1.1159 | 0.8671 | 0.4634 |
| S-Adenosylhomocysteine | 1.3570 | 0.3332 | 1.6325 | 0.5106 |
| S-Adenosylmethionine | 1.0985 | 0.8829 | 1.0161 | 1.0024 |
| Sarcosine | 1.0765 | 1.0459 | 1.0214 | 0.8563 |
| S-Carboxymethylcysteine | 0.9309 | 1.0691 | 1.0829 | 0.9171 |
| SDMA | 1.0891 | 1.0641 | 0.8259 | 1.0210 |
| Sebacic acid | 1.0056 | NA | 1.1099 | 0.6480 |
| Sedoheptulose 7-phosphate | 0.8458 | 0.5621 | 1.7024 | 0.8897 |
| Ser | 1.0909 | 1.3038 | 0.7568 | 0.8485 |
| Serotonin | 0.8235 | 1.0587 | 1.5528 | 0.5650 |
| S-Lactoylglutathione | 1.2754 | NA | 0.7826 | 1.1594 |
| S-Methylcysteine | 0.8175 | 1.1748 | 0.8123 | 1.1954 |
| S-Methylglutathione | 1.3210 | 0.4294 | 1.5702 | 0.6793 |
| S-Methylmethionine | 1.0318 | 1.1215 | 1.0841 | 0.7626 |
| Spermidine | 1.0464 | 0.8477 | 1.2583 | 0.8477 |
| Spermine | 0.9422 | 0.8222 | 1.2873 | 0.9482 |
| S-Sulfocysteine | 1.1369 | 1.7424 | 0.5622 | 0.5585 |
| Stachydrine | 1.1641 | 1.0539 | 0.8910 | 0.8910 |
| Suberic acid | 0.9850 | 0.6136 | 1.3564 | 0.4069 |
| Succinic acid | 0.9965 | 0.4327 | 1.8029 | 0.6261 |
| Sulfotyrosine | 1.0019 | 0.9538 | 1.0983 | 0.9461 |
| Taurine | 1.1348 | 1.4184 | 0.7234 | 0.7234 |
| Taurocholic acid | 1.7427 | 1.4243 | 0.7949 | 0.0381 |
| Taurocyamine | 1.0130 | 0.9967 | NA | NA |
| Thiamine | 1.2037 | 0.6685 | 1.1048 | 1.0231 |
| Thiamine diphosphate | NA | 1.0000 | NA | NA |
| Thiamine phosphate | 1.0833 | 0.8846 | 0.9551 | 1.0769 |
| Thiaproline | 1.0786 | 0.7981 | 0.8333 | 1.2899 |
| Thr | 1.0278 | 1.2083 | 0.8333 | 0.9306 |
| Threonic acid | 1.0466 | 1.0226 | 1.0406 | 0.8902 |
| threo-β-Methylaspartic acid | 0.9747 | 0.8448 | 1.0830 | 1.0542 |
| Thymidine | 0.4754 | 0.5437 | 1.3370 | 1.6440 |
| Thymine | 0.5000 | 0.5571 | 1.3071 | 1.6357 |
| trans-Cinnamic acid | 1.0930 | 0.9673 | 0.8794 | NA |
| trans-Glutaconic acid | 1.1908 | 0.6467 | 1.4073 | 0.6669 |
| Triethanolamine | 1.1747 | 1.1599 | 0.7286 | 0.9368 |
| Trigonelline | 1.0035 | 1.0732 | 1.0035 | 0.9199 |
| Trimethylamine | 0.8125 | 0.5315 | 1.4883 | 0.9112 |
| Trimethylamine N-oxide | 0.8245 | 0.8641 | 1.4285 | 0.8829 |
| Trp | 1.0657 | 1.0231 | 0.9805 | 0.9307 |
| Tyr | 1.2472 | 1.0067 | 0.9176 | 0.8285 |
| Tyr-Glu | 0.9524 | 1.2278 | 1.1134 | 0.7109 |
| Tyrosine methyl ester | 0.8679 | 0.8157 | 1.4551 | 0.8613 |
| UDP | NA | 0.9735 | 2.0354 | 0.4956 |
| "UDP-glucose UDP-galactose" | 0.6282 | 1.0974 | 1.0444 | 1.2565 |
| "UDP-N-acetylglucosamine UDP-N-acetylgalactosamine" | 0.7512 | 1.3042 | 1.2960 | 0.8007 |
| UMP | 0.5470 | 1.3292 | 1.5576 | 0.7260 |
| Uracil | 1.0114 | 0.7410 | 1.3416 | 0.9061 |
| Urea | 1.1564 | 1.0237 | 0.9289 | 0.8910 |
| Ureidoglycolic acid | NA | NA | NA | 1.0000 |
| Uric acid | 1.0675 | 0.6536 | 1.3333 | 0.9455 |
| Uridine | 1.1439 | 0.7292 | 1.3047 | 0.8222 |
| Urocanic acid | 1.0927 | 1.4248 | 0.6122 | 0.8703 |
| UTP | NA | 1.1122 | 1.6160 | 0.5798 |
| Val | 1.1220 | 1.0465 | 0.8906 | 0.9409 |
| Xanthine | NA | 1.4286 | 0.5714 | NA |
| Xanthosine | 0.6829 | 0.7815 | 1.5267 | 0.9542 |
| Xanthurenic acid | 0.9650 | NA | 1.0725 | 0.9600 |
| "XC0061 Propionylcarnitine" | 1.0988 | 0.8215 | 1.3551 | 0.7247 |
| "XC0089 Nicotinamide riboside" | 1.3443 | 0.7078 | 0.9657 | 0.9822 |
| Xylulose 5-phosphate | 1.0925 | 0.7283 | 1.4291 | 0.7895 |
| β-Ala | 1.2764 | 0.8420 | 1.1117 | 0.7699 |
| β-Ala-Lys | 0.9704 | 1.2097 | 0.8123 | 1.0077 |
| β-Tyr | 0.9761 | 1.0542 | 0.9436 | 1.0542 |
| γ-Butyrobetaine | 1.2043 | 1.0579 | 1.0248 | 0.7131 |
| γ-Glu-Ala | 1.0992 | 1.0496 | 0.9298 | 0.9215 |
| γ-Glu-Arg_divalent | 1.1576 | 0.9224 | 1.1153 | 0.8047 |
| γ-Glu-Asn | 1.3254 | 0.9773 | 0.9674 | 0.7300 |
| γ-Glu-Asp | 1.1715 | 1.0251 | 0.8787 | 0.9372 |
| γ-Glu-Citrulline | 1.1296 | 0.7841 | 1.1694 | 0.9169 |
| γ-Glu-Gln | 1.2227 | 0.8847 | 1.0512 | 0.8126 |
| γ-Glu-Glu | 1.2339 | 0.7260 | 1.3100 | 0.7301 |
| γ-Glu-Gly | 1.2570 | 0.9196 | 0.9801 | 0.8433 |
| γ-Glu-His | 1.2490 | 1.0114 | 1.0419 | 0.6976 |
| "γ-Glu-Ile γ-Glu-Leu" | 1.1761 | 0.9744 | 1.0188 | 0.8308 |
| γ-Glu-Lys_divalent | 1.1804 | 0.9737 | 1.0088 | 0.8371 |
| γ-Glu-Met | 1.1840 | 0.9120 | 1.0800 | 0.8240 |
| γ-Glu-Ornitine | 1.2439 | 0.8434 | 1.0629 | 0.7279 |
| γ-Glu-Phe | 1.1594 | 1.0104 | 1.0518 | 0.7785 |
| γ-Glu-Ser | 1.1790 | 0.9910 | 0.9837 | 0.8463 |
| γ-Glu-Taurine | 1.2242 | 0.9825 | 0.8655 | 0.9279 |
| γ-Glu-Thr | 1.1564 | 0.8720 | 1.0995 | 0.8720 |
| γ-Glu-Trp | 1.2126 | 0.9369 | 1.1462 | 0.7043 |
| γ-Glu-Tyr | 1.3825 | 0.8203 | 1.1060 | 0.6912 |
| γ-Glu-Val | 1.2676 | 0.7742 | 1.1157 | 0.8425 |
| γ-Glu-Val-Gly | 1.0607 | 1.0193 | 0.9304 | 0.9896 |
Factors:
| F1 | Model:Alzheimer’s disease model | Intervention:B. breve MCC1274 |
| F2 | Model:Alzheimer’s disease model | Intervention:Saline |
| F3 | Model:Wild type | Intervention:B. breve MCC1274 |
| F4 | Model:Wild type | Intervention:Saline |
