Data for (Study ST002160)
(Analysis AN003539)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 |
|---|---|---|---|
| 11(E)-Eicosenoic Acid | 1.6155 | 1.2508 | 0.3503 |
| 11(Z),14(Z)-Eicosadienoic Acid | 1.4763 | 1.1540 | 0.5273 |
| 13Z,16Z-Docosadienoic Acid | 1.7853 | 1.0564 | 0.3687 |
| 16-Hydroxyhexadecanoic acid | 1.1895 | 1.2094 | 0.7008 |
| 1-Methylhistamine | 1.3731 | 0.9452 | 0.7613 |
| 1-Methylnicotinamide | 1.1865 | 1.1254 | 0.7660 |
| 2-Arachidonyl glycerol ether | 1.2705 | 1.0891 | 0.7303 |
| 2^-Deoxycytidine | 1.0040 | 1.0239 | 0.9790 |
| 3-Hydroxy-3-methylglutaric acid | 1.2436 | 0.9925 | 0.8229 |
| 3-Methylhistidine | 1.1270 | 0.9745 | 0.9238 |
| 3-Phosphoglyceric acid | 1.1966 | 1.1383 | 0.7488 |
| 3-Ureidopropionic acid | 1.6863 | 1.0147 | 0.4742 |
| 4-Guanidinobutyric acid | 1.0049 | 0.9762 | 1.0142 |
| 4-Hydroxyproline | 0.9990 | 1.0269 | 0.9806 |
| 4-Oxoproline | 1.2012 | 1.2206 | 0.6836 |
| 4-tert-Octylphenol | 1.1912 | 1.0748 | 0.8005 |
| 5-Aminolevulinic acid | 1.3704 | 0.9090 | 0.7904 |
| 5-Thymidylic acid | 1.0768 | 1.2073 | 0.7869 |
| 7-Methylguanine | 1.6515 | 1.0475 | 0.4758 |
| (±)9-HpODE | 0.2834 | 0.9495 | 1.5754 |
| 9-Oxo-ODE | 0.1842 | 0.9456 | 1.6527 |
| Acetyl-CoA | 1.1011 | 1.0468 | 0.8890 |
| Adenine | 0.8204 | 1.7936 | 0.5395 |
| Adenosine | 1.0088 | 1.4705 | 0.6406 |
| Adenosine diphosphate ribose | 1.2390 | 1.2769 | 0.6130 |
| Adenosine monophosphate | 1.0535 | 1.0991 | 0.8856 |
| Adenosine triphosphate | 1.0355 | 0.9590 | 1.0041 |
| ADP | 1.0117 | 0.9452 | 1.0323 |
| Allantoin | 1.0296 | 1.0122 | 0.9687 |
| Aminoadipic acid | 0.6991 | 1.0010 | 1.2250 |
| Arachidonic acid | 1.0289 | 1.3249 | 0.7346 |
| Argininosuccinic acid | 1.1401 | 1.2471 | 0.7096 |
| Ascorbic acid | 1.1712 | 0.9672 | 0.8962 |
| Azelaic acid | 0.9710 | 1.6269 | 0.5515 |
| Betaine | 0.8266 | 0.9572 | 1.1622 |
| CDP | 1.0996 | 1.0294 | 0.9032 |
| Choline | 1.3089 | 0.9888 | 0.7767 |
| cis-Aconitic acid | 1.1806 | 0.9857 | 0.8753 |
| Citraconic acid | 1.5479 | 1.1225 | 0.4972 |
| Citric acid | 1.1113 | 1.0026 | 0.9146 |
| Citrulline | 1.0502 | 1.0248 | 0.9437 |
| Creatine | 0.9340 | 1.0080 | 1.0436 |
| Creatinine | 1.1771 | 1.0424 | 0.8354 |
| Cystathionine | 0.6802 | 0.8825 | 1.3280 |
| Cytidine | 1.7586 | 1.0159 | 0.4192 |
| Cytidine 5^-diphosphocholine | 1.3230 | 1.0506 | 0.7198 |
| Cytidine 5^-monophosphate (hydrate) | 1.0885 | 1.0267 | 0.9136 |
| Cytidine monophosphate | 1.1973 | 1.0068 | 0.8469 |
| D-2-Hydroxyglutaric acid | 1.1334 | 1.0157 | 0.8882 |
| Deoxyadenosine monophosphate | 1.1187 | 1.4068 | 0.6059 |
| Deoxyribose 5-phosphate | 1.0031 | 0.9826 | 1.0107 |
| D-Fructose | 1.1046 | 1.0391 | 0.8922 |
| DHAP/GAP | 1.3570 | 1.5140 | 0.3467 |
| Diaminopimelic acid | 1.2299 | 1.0607 | 0.7821 |
| Dihomo-?-Linolenic Acid | 1.4875 | 1.0640 | 0.5864 |
| DL-4-Hydroxyphenyllactic acid | 1.3211 | 1.0748 | 0.7031 |
| Docosahexaenoic Acid | 1.6041 | 0.8974 | 0.6239 |
| D-(-)-Quinic acid | 0.1776 | 0.8578 | 1.7234 |
| D-Saccharic acid | 1.2568 | 1.0458 | 0.7730 |
| D-Sedoheptulose 7-phosphate | 1.3257 | 1.0341 | 0.7301 |
| Erucic acid | 1.7498 | 1.1798 | 0.3028 |
| FAD | 1.0399 | 0.9251 | 1.0263 |
| Fructose 1,6-bisphosphate | 1.4134 | 1.4270 | 0.3697 |
| Glucosamine | 1.5794 | 1.2116 | 0.4067 |
| Glucose 1-phosphate | 1.3568 | 1.0508 | 0.6943 |
| Glucose 6-phosphate | 1.1543 | 1.1273 | 0.7888 |
| Glutathione | 1.1392 | 1.0065 | 0.8907 |
| Glycerol 3-phosphate | 1.1935 | 1.0556 | 0.8132 |
| Glycine | 1.0662 | 1.0228 | 0.9332 |
| Glycyl-L-leucine | 1.2277 | 1.0585 | 0.7853 |
| Guanidineacetic acid | 1.2448 | 1.0138 | 0.8061 |
| Guanidinoethyl sulfonate | 1.0721 | 0.9910 | 0.9527 |
| Guanosine 5^-diphospho-D-mannose | 1.0649 | 1.0663 | 0.9016 |
| Guanosine 5^-diphospho-ß-L-fucose | 1.1341 | 0.9705 | 0.9216 |
| Guanosine diphosphate | 0.9747 | 0.9290 | 1.0722 |
| Guanosine monophosphate | 1.0605 | 1.1329 | 0.8550 |
| Guanosine triphosphate | 1.1324 | 0.9115 | 0.9671 |
| Guvacoline | 1.0545 | 0.9997 | 0.9594 |
| Hexanoylcarnitine | 1.3339 | 0.9751 | 0.7683 |
| Hippuric acid | 1.4698 | 1.5456 | 0.2384 |
| Histamine | 1.7476 | 0.9932 | 0.4444 |
| Hypotaurine | 0.8473 | 0.9662 | 1.1399 |
| Hypoxanthine | 1.1692 | 1.4939 | 0.5027 |
| Indole-3-lactic acid | 1.2698 | 1.1013 | 0.7217 |
| Inosine | 1.1333 | 1.5707 | 0.4720 |
| Inosinic acid | 1.2472 | 1.0219 | 0.7982 |
| L-Acetylcarnitine | 1.2596 | 0.9877 | 0.8146 |
| L-Alanine | 1.1073 | 1.0293 | 0.8976 |
| L-Arginine | 1.0908 | 1.1156 | 0.8452 |
| L-Asparagine | 1.0824 | 1.0735 | 0.8830 |
| L-Aspartic acid | 1.0521 | 1.0256 | 0.9417 |
| Lauric acid | 0.1867 | 2.8621 | 0.2134 |
| L-Carnitine | 1.1537 | 0.9669 | 0.9096 |
| L-Cysteinesulfinic acid | 1.2824 | 1.0528 | 0.7486 |
| L-Ergothioneine | 0.8773 | 0.9907 | 1.0990 |
| Leucylproline | 1.3366 | 1.1603 | 0.6273 |
| L-Glutamic acid | 1.0326 | 1.0375 | 0.9475 |
| L-Glutamine | 0.8482 | 1.1094 | 1.0318 |
| L-Glutathione oxidized | 0.9666 | 1.1975 | 0.8770 |
| Lignoceric Acid | 1.1455 | 0.9692 | 0.9139 |
| Linoleic Acid | 1.1715 | 1.2305 | 0.6986 |
| ?-Linolenic Acid | 1.2268 | 0.9391 | 0.8756 |
| L-Isoleucine | 1.3229 | 1.0349 | 0.7317 |
| L-Lactic acid | 1.3121 | 1.1771 | 0.6331 |
| L-Leucine | 1.2261 | 1.1181 | 0.7418 |
| L-Lysine | 1.1927 | 1.0278 | 0.8346 |
| L-Methionine | 1.1359 | 1.0518 | 0.8592 |
| L-Phenylalanine | 1.2359 | 1.1116 | 0.7394 |
| L-Proline | 1.2623 | 1.0229 | 0.7861 |
| L-Serine | 1.0704 | 1.0654 | 0.8982 |
| L-(+)-Tartaric acid | 0.0271 | 3.2775 | 0.0216 |
| L-Threonine | 1.0568 | 1.0349 | 0.9312 |
| L-Tryptophan | 1.2890 | 1.0809 | 0.7226 |
| L-Tyrosine | 1.2151 | 1.0948 | 0.7675 |
| L-Valine | 0.9385 | 0.9773 | 1.0631 |
| Malic acid | 1.1272 | 0.9879 | 0.9137 |
| Methionine sulfoxide | 1.2782 | 1.2170 | 0.6286 |
| Mevalonic acid | 1.7540 | 0.8803 | 0.5243 |
| Myo-inositol | 1.1210 | 0.9939 | 0.9138 |
| N6-Acetyl-L-lysine | 1.0853 | 1.0550 | 0.8948 |
| N6,N6,N6-Trimethyl-L-lysine | 1.4167 | 1.0009 | 0.6868 |
| N-Acetyl-D-galactosamine 4-sulfate | 0.9306 | 0.9815 | 1.0659 |
| N-Acetyl-D-glucosamine | 1.1601 | 0.9526 | 0.9155 |
| N-Acetyl-L-aspartic acid | 0.8745 | 1.0037 | 1.0913 |
| N-Acetylneuraminic acid | 0.9569 | 1.0330 | 1.0076 |
| N-Acetylornithine | 1.1926 | 1.0104 | 0.8477 |
| N-Acetylputrescine | 1.4151 | 0.9889 | 0.6970 |
| N-Acetyl-α-D-glucosamine 1-phosphate | 1.0701 | 1.0603 | 0.9022 |
| NAD | 1.0273 | 1.0147 | 0.9685 |
| NADH | 1.1130 | 1.0238 | 0.8974 |
| NADP | 1.0567 | 0.8885 | 1.0410 |
| NADPH | 0.9921 | 1.0450 | 0.9721 |
| Nervonic acid | 1.6888 | 1.0208 | 0.4678 |
| N-Glycolylneuraminic acid | 1.3121 | 1.1077 | 0.6852 |
| Nicotinamide | 1.5455 | 1.1122 | 0.5067 |
| Oleic Acid | 1.2427 | 1.2249 | 0.6493 |
| Oleoyl-L-α-lysophosphatidic acid | 1.3948 | 0.6921 | 0.9348 |
| O-Phosphorylethanolamine | 1.0113 | 0.9725 | 1.0122 |
| Ornithine | 1.0925 | 1.0221 | 0.9141 |
| Oxoglutaric acid | 0.9792 | 0.9942 | 1.0200 |
| Palmitoylcarnitine | 1.1853 | 1.0441 | 0.8279 |
| Pantothenic acid | 1.1848 | 0.9749 | 0.8802 |
| Phosphoenolpyruvic acid | 1.0301 | 1.0330 | 0.9526 |
| Pipecolic acid | 1.1042 | 0.8897 | 1.0046 |
| Prolylleucine | 2.0966 | 1.1094 | 0.0955 |
| Propionylcarnitine | 1.2279 | 0.9469 | 0.8689 |
| Pseudouridine | 1.3752 | 1.0454 | 0.6846 |
| Pyruvic acid | 1.6490 | 1.0177 | 0.5000 |
| S-Adenosylhomocysteine | 1.1625 | 0.9902 | 0.8855 |
| S-Adenosylmethionine | 0.9645 | 0.9991 | 1.0273 |
| Sarcosine | 1.1620 | 0.9823 | 0.8918 |
| Succinic acid | 1.3990 | 1.0380 | 0.6722 |
| Symmetric dimethylarginine | 1.3490 | 1.0218 | 0.7219 |
| Taurine | 1.0248 | 1.0431 | 0.9491 |
| Thiamine pyrophosphate | 0.9953 | 1.0015 | 1.0024 |
| UDP-N-acetylglucosamine | 1.0406 | 1.0256 | 0.9504 |
| Uracil | 1.6794 | 0.9543 | 0.5247 |
| Uric acid | 1.2888 | 1.1895 | 0.6413 |
| Uridine | 0.9680 | 1.0561 | 0.9820 |
| Uridine 5^-diphosphate (UDP) | 0.8649 | 0.9899 | 1.1089 |
| Uridine 5^-diphosphogalactose | 1.1159 | 0.9971 | 0.9153 |
| Uridine 5^-diphosphoglucuronic acid | 0.9660 | 1.0407 | 0.9950 |
| Uridine 5^-monophosphate | 0.9877 | 1.0253 | 0.9903 |
| Xanthosine | 1.3048 | 1.3264 | 0.5266 |
| Xanthosine 5^-monophosphate | 1.4772 | 1.0433 | 0.6096 |
| Υ-L-Glutamyl-L-glutamic acid | 1.4552 | 1.0505 | 0.6207 |
Factors:
| F1 | Alox12/15 Status:KO |
| F2 | Alox12/15 Status:n/a |
| F3 | Alox12/15 Status:WT |
