Data for (Study ST002179)

(Analysis AN003568)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
10-hydroxy capric acid 1.1013 0.9100
12-Hydroxydodecanoic acid 1.4322 0.6158
1-Aminocyclopropane-1-carboxylic acid 0.9814 1.0166
1-Methyladenosine 1.0041 0.9963
1-methylhistidine 0.9122 1.0780
2-Aminoisobutyric acid 1.0105 0.9907
2-Deoxy-D-Ribose 1.1462 0.8701
2-Deoxyglucose 0.8115 1.1676
2-Methylglutaric acid 1.1557 0.8616
3,4-Dihydroxybenzoic acid 0.9718 1.0251
3-Amino-4-hydroxybenzoic acid 1.0002 0.9999
3-hydroxy-3-methyl-Glutaric acid 0.9316 1.0608
3-Hydroxyphenylacetic acid 2.1248 0.0002
3-Methoxy-4-hydroxyphenylethylene glycol 1.0488 0.9566
3-Methyladenine 0.9600 1.0355
3-Methylglutaric acid 1.1580 0.8596
3-Ureidopropionic acid 0.7745 1.2004
4-acetamidobutanoate 0.8343 1.1473
4-Hydroxy-L-phenylglycine 0.8942 1.0940
4-Hydroxyphenylpyruvic acid 0.9387 1.0544
4-Pyridoxic acid 1.0778 0.9309
5?-Deoxy-5?-(methylthio)adenosine 0.9458 1.0482
5-Hydroxyindoleacetic acid 0.8583 1.1259
5-Methylcytosine 2.1199 0.0045
6-Deoxy-L-galactose 0.8152 1.1642
Acetyl-L-tyrosine 1.9095 0.1916
Adenine 0.9720 1.0249
Adenosine 1.1814 0.8387
Adenosine5^-monophosphate 1.1840 0.8364
Adipic acid 1.1634 0.8548
AHBA 1.0002 0.9999
Allothreonine 0.9619 1.0338
?-Aminobutryic acid 1.0034 0.9970
a-N-Acetylglucosamine 0.9291 1.0630
Caffeine 0.8945 1.0938
Carnitine 1.1309 0.8836
Chenodeoxycholic Acid 0.9927 1.0065
Citrulline 0.7857 1.1905
Cortexolone 1.3045 0.7293
Corticosterone 1.3110 0.7236
Creatine 1.0210 0.9813
Creatinine 0.9844 1.0139
Cytidine 0.9567 1.0385
Cytosine 0.9613 1.0344
D-Alanine 1.0202 0.9820
D-Aspartic acid 0.9149 1.0757
Deoxycytidine 0.8978 1.0908
Deoxyguanosine 1.1794 0.8405
Deoxyuridine monophosphate (dUMP) 1.0030 0.9974
D-Fructose 6-phosphate 1.0581 0.9483
?-D-Galactose 1-phosphate 1.0581 0.9483
D-Glucosamine 6-phosphate 0.9199 1.0712
?-D-Glucose 1-phosphate 1.0581 0.9483
D-Glucose 6-phosphate 1.0581 0.9483
Diacetyl 1.0104 0.9908
Diaminopimelic acid 0.8284 1.1526
Diethanolamine 0.9273 1.0646
Dihydrouracil 2.1236 0.0013
Dihydroxyphenylacetic acid 1.1455 0.8707
DL-3-amino-isobutanoic acid 1.0020 0.9982
DL-Homoserine 0.9619 1.0338
DL-pipecolic acid 0.9601 1.0355
D-(-)-Lyxose 0.8981 1.0906
D-(+)-Malic acid 1.0547 0.9514
D-Mannitol 0.7747 1.2003
D-MANNOSAMINE 0.9225 1.0689
D-Mannose 6-phosphate 1.0581 0.9483
D-Ornithine 0.9735 1.0235
D-Ribose 0.8980 1.0906
D-Ribose 5-phosphate 1.0402 0.9643
D-Sorbitol 0.7747 1.2003
D-Tryptophan 0.8861 1.1013
Dulcitol 0.7747 1.2002
D-(+)-Xylose 0.8981 1.0906
(-)-Epinephrine 1.0583 0.9482
Erythritol 1.1567 0.8607
Ethylmalonic acid 1.0803 0.9286
Glucosamine 0.9225 1.0689
Glutamine 0.9294 1.0628
Glutamyl-Tyrosine 1.6833 0.3927
Glyceraldehyde 1.2019 0.8206
Glycerol 2-phosphate 1.0017 0.9985
Glyceryl phosphate 1.0018 0.9984
Guanine 1.2956 0.7373
Hippuric acid 0.8134 1.1658
Histamine 1.7198 0.3602
Hypoxanthine 1.0470 0.9582
Inosine 0.9869 1.0117
Inosine 5^-monophosphate (IMP) 1.8351 0.2577
Isocitrate 0.9138 1.0766
Ketoleucine 1.0492 0.9562
Kynurenine 0.6844 1.2806
L-Alanine 1.0196 0.9826
L-Anserine 0.9782 1.0194
L-(-)-Arabitol 0.8953 1.0931
L-Arginine 0.8768 1.1095
L-Asparagine 1.1278 0.8864
L-Aspartic Acid 0.9155 1.0751
L-Histidine 1.0305 0.9729
L-Isoleucine 0.9656 1.0306
L-Leucine 0.9587 1.0367
L-Lysine 0.9893 1.0095
L-Methionine 0.9841 1.0141
L-Norleucine 0.9646 1.0315
L-Norvaline 1.0021 0.9981
L-Ornithine 0.9734 1.0236
L-Phenylalanine 0.9415 1.0520
L-Pipecolic acid 0.9598 1.0357
L-Proline 0.8614 1.1232
L-Serine 1.0452 0.9598
L-(-)Sorbose 0.5430 1.4062
L-Threonine 0.9619 1.0338
L-Tryptophan 0.8861 1.1013
L-Tyrosine 1.8259 0.2659
L-Valine 0.9361 1.0568
Maleamic acid 1.0523 0.9535
Malic acid 1.0594 0.9472
METHYL BETA-D-GALACTOSIDE 1.0481 0.9573
Methyl jasmonate 1.0464 0.9588
Methyl N-(a-methylbutyryl)glycine 1.0389 0.9654
Monomethyl glutaric acid 1.4102 0.6354
myo-Inositol 0.6444 1.3161
N-acetylaspartate 0.9460 1.0480
N-Acetyl-D-galactosamine 0.9291 1.0630
N-Acetyl-DL-methionine 0.8583 1.1259
N-Acetyl-DL-serine 0.9987 1.0012
N-Acetyl-?-D-mannosamine 0.9291 1.0630
N-Acetyl-L-alanine 0.9665 1.0298
N-Acetyl-L-glutamic acid 0.7345 1.2360
N-Acetylneuraminic Acid 0.9392 1.0540
N-ALPHA-ACETYL-L-ASPARAGINE 0.8928 1.0953
N-Formylmethionine 0.9180 1.0729
Niacinamide 0.9564 1.0388
N-Methyl-D-aspartic acid 1.1307 0.8839
N-Methylhistamine 0.8290 1.1520
N?,N?,N?-Trimethyllysine 0.9441 1.0497
O-Acetylserine 0.9869 1.0117
Octopamine (p-Hydroxyphenylethanolamine) 0.8976 1.0910
Oleic Acid 0.7511 1.2213
O-Phosphorylethanolamine 1.0309 0.9725
Pantothenic Acid 0.9094 1.0805
Petroselinic acid 0.7508 1.2215
Phosphocreatine 0.9429 1.0507
p-Hydroxyphenylacetic acid 2.1248 0.0002
Pimelic acid 1.2365 0.7897
Pyridoxal Phosphate 0.7040 1.2631
Pyridoxamine 1.0615 0.9454
Pyroglutamic acid 0.9724 1.0245
Quinic acid 0.8255 1.1551
RAC-GLYCEROL 1-MYRISTATE 1.1450 0.8711
Ribitol 0.8953 1.0931
Riboflavin (Vitamin B2) 0.9456 1.0483
R-(-)-Mandelic acid 1.1026 0.9088
S-(5-ADENOSYL)-L-METHIONINE 1.0490 0.9564
S-Adenosylhomocysteine 0.9496 1.0448
salsolinol 0.6400 1.3200
Sarcosine 1.0207 0.9816
Spermidine 0.8657 1.1194
Suberic acid 1.2810 0.7503
Succinylacetone HT-1 1.3297 0.7069
Taurine 1.3037 0.7301
Theobromine 0.9654 1.0308
Theophylline 0.8095 1.1693
Thiamine monophosphate 0.9764 1.0209
Thymidine 1.0215 0.9809
Trigonelline 0.7122 1.2559
Uracil 1.0669 0.9406
Uridine 0.9306 1.0617
Uridine monophosphate (UMP) 1.3507 0.6883
Urocanic acid 0.8299 1.1512
Xanthine 0.9858 1.0126
Xanthosine 0.9845 1.0138
Xanthurenic acid 0.4506 1.4884
Xylitol 0.8953 1.0931
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Factors:

F1Treatment group:Nitisinone
F2Treatment group:No Treatment (control)
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