Data for (Study ST002224)

(Analysis AN003633)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4
2/3-phosphoglycerate 1.1664 1.0677 0.8222 0.9437
2-hydroxyglutarate 1.0382 1.1379 1.1169 0.7070
2-oxoglutarate 1.1333 1.0524 1.2381 0.5763
4-guanidinobutanoate 0.5861 0.9876 0.7074 1.7188
4-hydroxyphenyllactate 0.7071 0.7952 0.7539 1.7438
4-hydroxyproline 0.4291 0.4680 0.4162 2.6867
5-aminolevulinate 0.8706 0.9806 0.8698 1.2790
6-phosphogluconate 0.8523 1.0582 0.7857 1.3038
acetyl-CoA 0.8187 1.0431 1.0571 1.0811
aconitate 1.0264 1.0698 1.1806 0.7232
adenosine 0.7261 1.0365 1.1304 1.1070
ADP 0.8085 1.0780 0.9125 1.2010
ADP-ribose 0.9622 0.9953 0.9239 1.1186
AICAR 1.3279 0.4074 1.3635 0.1110
alanine 0.5436 0.5492 0.5446 2.3626
aminoadipate 0.9197 0.7974 1.2066 1.0763
AMP 0.9038 1.0688 0.9651 1.0623
arginine 1.0133 1.0340 0.9473 1.0054
argininosuccinate 1.1440 0.8207 0.2613 1.7741
asparagine 0.5392 0.6151 0.4587 2.3870
aspartate 1.0160 1.1480 0.9121 0.9239
ATP 0.7527 1.0724 0.9236 1.2513
beta-alanine 0.6282 0.7196 0.6850 1.9673
beta-citrylglutamate 0.8528 1.0128 0.7865 1.3479
betaine 0.6795 0.6723 0.9150 1.7331
carnitine 0.9196 0.8648 1.3542 0.8614
carnitine C14 0.3575 0.3031 0.9693 2.3701
carnitine C18 0.7504 1.1321 1.2967 0.8208
carnitine C2 0.8469 0.8727 1.2050 1.0753
carnitine C3 0.8392 0.8829 1.1129 1.1649
carnitine C4 0.8671 0.7087 0.9850 1.4392
carnitine C5 0.9509 1.1129 1.2709 0.6653
carnitine C6 0.7248 0.7329 1.0714 1.4709
carnosine 1.0191 1.0706 0.7896 1.1207
CDP 0.8749 0.9775 1.0054 1.1422
CDP-ethanolamine 0.3470 0.8768 0.1709 2.6054
choline 0.8933 1.2415 0.5319 1.3334
citicoline 0.4848 0.9781 0.2658 2.2713
citrate 1.0303 1.0068 1.0635 0.8995
citrulline 0.8151 0.8930 0.7796 1.5123
CMP 0.9348 0.9068 1.1419 1.0165
CMP-N-acetylneuraminate 0.8689 0.9887 1.0274 1.1150
creatine 1.0558 0.9340 1.0792 0.9310
creatinine 0.9653 1.0026 0.9343 1.0978
CTP 0.8346 1.0011 0.9955 1.1689
cyclic ADP-ribose 0.9321 1.0170 0.8982 1.1527
cyclic AMP 0.7295 0.9586 1.0848 1.2271
cystathionine 0.1905 0.1175 0.3219 3.3701
cysteate 1.1281 1.3482 1.0782 0.4454
cysteinylglycine 0.6974 0.6903 0.9821 1.6302
cytidine 0.8336 1.1344 0.7945 1.2376
cytosine 0.9313 1.0311 0.9382 1.0994
dATP 0.6027 0.9786 0.7975 1.6212
dCTP 0.8512 1.0241 0.7669 1.3578
deoxyadenosine 0.7750 1.0341 1.0224 1.1685
deoxycarnitine 0.7540 0.7131 1.1672 1.3657
deoxycytidine 0.8572 0.9331 0.9798 1.2299
deoxyribose 5-phosphate 1.1185 1.4291 1.0187 0.4337
dihydroorotate 0.5191 1.5532 1.0124 0.9153
dihydroxyacetone phosphate 0.9427 1.1835 0.9299 0.9439
dTTP 0.7740 0.9649 0.9597 1.3015
epsilon-(gamma-glutamyl)lysine 0.9212 1.0939 0.7359 1.2490
FAD 0.7824 1.2670 1.1884 0.7623
fructose 6-Phosphate 0.8229 1.2345 0.9082 1.0345
fructose bisphosphate 0.9319 1.0604 0.8862 1.1215
fumarate 0.9358 0.9048 0.9810 1.1784
gamma-glutamylcysteine 0.6765 0.4980 1.0951 1.7304
gamma-glutamylglutamate 0.9392 1.0283 1.0830 0.9494
GDP 0.8170 1.1379 1.0102 1.0349
GDP-glucose 0.9775 1.1654 0.8994 0.9576
gluconate 0.3262 0.2645 0.4722 2.9371
glucose 1.0177 1.2134 0.8903 0.8785
glucose 1-phosphate 0.7640 0.9188 0.7560 1.5612
glucose 6-phosphate 0.7305 1.3210 0.9527 0.9957
glucuronate 0.9106 0.7239 1.4110 0.9546
glutamate 0.9965 1.0373 0.9974 0.9688
glutamine 0.9350 0.9896 0.7188 1.3565
glutathione reduced 0.7484 0.7242 1.0090 1.5185
glyceraldehyde 3-phosphate 0.8748 0.8038 1.2218 1.0997
glycerol 3-phosphate 0.8179 1.2129 0.4356 1.5336
glycerophosphoethanolamine 0.7027 1.1142 0.4691 1.7141
glycerylphosphorylcholine 0.8456 1.6895 0.4788 0.9861
glycine 0.3350 0.4226 0.2728 2.9696
GMP 0.8261 1.0906 0.9806 1.1027
GTP 0.8098 1.1226 1.0003 1.0673
guanosine 0.8607 1.2339 0.9057 0.9997
histidine 0.7922 0.8121 0.7834 1.6123
homoarginine 1.0218 0.8967 1.0680 1.0135
hypotaurine 0.9647 0.9220 1.3815 0.7318
hypoxanthine 0.8587 0.6483 1.2391 1.2539
IMP 1.3024 0.7663 1.0944 0.8369
inosine 0.7539 0.8702 1.2453 1.1305
inositol 1.1610 1.3452 1.0116 0.4822
isoleucine 0.8696 0.9736 0.7838 1.3731
ketoleucine+ketoisoleucine 0.9614 1.0000 0.9299 1.1087
lactate 1.0294 1.0401 0.8407 1.0899
leucine 0.8205 0.9719 0.7381 1.4696
lysine 1.0258 0.9791 0.9823 1.0128
malate 0.9514 0.9054 0.9814 1.1619
malonate 0.9817 0.9464 0.9250 1.1407
malonylcarnitine 1.1012 1.0644 1.6458 0.1886
methionine 0.7239 0.9134 0.6021 1.7607
methionine sulfoxide 0.8080 0.7199 0.9093 1.5628
methylhistidine 0.8538 0.9495 0.7950 1.4016
methylmalonylcarnitine/succinylcarnitine 1.2532 1.4192 1.0194 0.3081
methylthioadenosine 0.7914 0.8459 0.9020 1.4607
mevalonate 5-pyrophosphate 0.8002 0.8832 1.4172 0.8994
N6,N6,N6-trimethyllysine 0.8692 0.8001 1.1327 1.1980
N-acetylalanine 0.8077 0.8560 0.8687 1.4675
N-acetylarginine 0.4191 0.2655 0.5012 2.8143
N-acetylaspartate 0.0605 0.0718 0.3615 3.5062
N-acetylaspartylglutamate 0.0104 0.0152 0.0618 3.9126
N-acetylglutamate 0.5375 0.5429 0.5785 2.3411
N-acetylglutamine 0.4954 0.4915 0.4702 2.5430
N-acetylhexosamine phosphate 1.0773 0.9517 1.2028 0.7681
N-acetylhistidine 0.8879 1.0138 0.6699 1.4284
N-acetylmethionine 0.6320 0.6363 0.6434 2.0883
N-acetylneuraminate 1.2855 1.0668 1.0046 0.6430
N-acetylserine 0.7569 0.7172 0.8290 1.6970
NAD 0.9347 1.0297 0.9108 1.1249
NADH 1.1677 0.6465 0.3379 1.8479
NADP 0.6047 1.2060 1.2251 0.9642
NADPH 1.0754 1.2142 0.8746 0.8358
N-carbamoylaspartate 0.5942 1.9472 0.5841 0.8745
N,N-dimethylarginine 0.9099 0.8751 1.0916 1.1233
ophthalmate 0.6548 0.8667 0.5191 1.9594
ornithine 0.6542 0.6005 0.5367 2.2086
orotate 0.3657 2.3094 0.3107 1.0141
orotidine 1.3495 0.8981 1.4444 0.3080
oxidized glutathione 0.6509 0.6024 0.9435 1.8032
pantothenate 0.9802 0.9761 1.1919 0.8518
pentose phosphate 0.9663 0.9210 0.9753 1.1373
phenylalanine 0.8169 0.9649 0.7566 1.4617
phosphocreatine 0.0238 0.0053 0.0141 3.9568
phosphoenolpyruvate 1.2951 1.0912 0.8005 0.8133
phosphoethanolamine 0.0398 0.2170 0.0337 3.7095
phosphorylcholine 0.4996 0.6247 0.8472 2.0286
proline 0.7843 0.7725 0.7638 1.6793
pyroglutamate 0.9778 0.9151 0.9525 1.1546
pyruvate 0.9887 1.1685 0.9313 0.9115
S-(2-succinyl)cysteine 0.4015 0.3484 0.3730 2.7685
S-adenosylhomocysteine 0.8268 0.7921 0.9366 1.4445
S-adenosylmethionine 1.0836 1.2119 1.0198 0.6847
SAICAR 0.9449 0.3019 1.2878 NA
sedoheptulose 7-phosphate 1.0498 0.9273 0.5835 1.4393
serine 0.3695 0.4615 0.3102 2.8588
S-lactoylglutathione 0.9303 0.7827 1.0767 1.2104
S-succinylglutathione 0.5405 0.4685 0.5774 2.4136
succinate 0.7691 0.8438 0.8580 1.5291
taurine 1.0249 0.9789 1.3632 0.6329
thiamine 0.7937 0.8664 0.8861 1.4538
threonine 0.4974 0.5566 0.4663 2.4797
tryptophan 0.8365 0.9329 0.7890 1.4416
tyrosine 0.8939 0.9067 0.8323 1.3671
UDP 0.9219 0.9521 1.0748 1.0512
UDP-GlcNac 0.8112 0.9238 0.9157 1.3494
UDP-glucose 0.9147 0.8942 1.0223 1.1688
UMP 1.0277 1.0039 1.1457 0.8228
uric acid 1.0055 0.9922 0.9685 1.0339
uridine 0.7738 0.9541 1.2064 1.0657
UTP 0.8929 0.9649 1.1115 1.0308
valine 0.8958 1.0066 0.8264 1.2711
xanthine 0.9337 1.0280 0.7635 1.2748
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Factors:

F1Cell line:786-M1A | Treatment:Plasmax + 2.5% FBS
F2Cell line:786-M2A | Treatment:Plasmax + 2.5% FBS
F3Cell line:786-O | Treatment:Plasmax + 2.5% FBS
F4Cell line:HK2 | Treatment:Plasmax + 2.5% FBS
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