Data for (Study ST002228)
(Analysis AN003637)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1,5-Anhydrosorbitol | 1.5903 | 0.3254 | 1.1471 | 1.6900 | 0.4429 | 1.0944 | 1.3968 | 0.5192 | 1.0873 | 1.3868 | 0.4608 | 0.9536 |
1-Hexadecanol | 0.8181 | 1.0308 | 0.7168 | 0.7004 | 1.4062 | 0.9392 | 0.6195 | 1.1225 | 0.7717 | 1.7662 | 1.0304 | 1.1283 |
2,3-Dihydroxybutanedioic acid | 0.9120 | 0.4139 | 1.6747 | 0.8170 | 0.6017 | 1.4842 | 0.9073 | 0.6023 | 1.4056 | 0.9675 | 0.5964 | 1.6212 |
2-Aminoheptanedioic acid | 1.0421 | 0.4782 | 0.7493 | 1.2624 | 0.6935 | 1.3358 | 1.5783 | 1.0131 | 1.1947 | 1.1100 | 0.9446 | 0.7760 |
2-Hydroxy-3-methylbutyric acid | 0.9416 | 0.1428 | 0.3998 | 0.9033 | 0.2277 | 0.4285 | 2.7000 | 1.0418 | 1.4802 | 2.7534 | 0.9831 | 1.4373 |
2-Hydroxybutyric acid | 1.1942 | 0.2934 | 1.3390 | 1.6713 | 0.5537 | 1.3250 | 0.9983 | 0.3638 | 1.2096 | 1.1461 | 0.4132 | 1.4050 |
2-Phosphoglyceric acid | 0.7138 | 0.2128 | 0.1246 | 0.9277 | 0.1939 | 0.1201 | 2.8404 | 0.1363 | 0.1119 | 7.9755 | 0.2532 | 0.1526 |
3-aminoglutaric acid_1 | 0.8112 | 0.1722 | 2.0197 | 0.6194 | 0.3946 | 2.0976 | 0.4602 | 0.2467 | 2.1512 | 0.3821 | 0.2958 | 2.1673 |
3-aminoglutaric acid_2 | 0.9693 | 0.7946 | 0.9858 | 0.8157 | 0.7865 | 0.9784 | 0.8921 | 1.4551 | 0.9368 | 0.9670 | 1.9164 | 0.8111 |
3-Hydroxyanthranilic acid | 0.5262 | 0.1578 | 1.5440 | 0.3769 | 0.1484 | 1.5394 | 1.1745 | 0.1231 | 2.2226 | 2.3819 | 0.1601 | 2.2956 |
3-Hydroxybutyric acid | 1.8230 | 0.4754 | 1.6527 | 1.5904 | 0.5802 | 0.9562 | 0.8931 | 0.3421 | 1.0548 | 1.0774 | 0.3754 | 1.0055 |
3-Hydroxyisovaleric acid | 1.0748 | 0.4939 | 1.1839 | 0.9896 | 0.5554 | 1.2470 | 1.1865 | 0.5997 | 1.6483 | 1.1144 | 0.6556 | 1.4876 |
3-Phosphoglyceric acid | 0.7241 | 0.2111 | 0.1533 | 0.9734 | 0.1780 | 0.1499 | 3.0671 | 0.1233 | 0.1362 | 7.5996 | 0.2528 | 0.1546 |
4-Hydroxybenzoic acid | 0.4716 | 0.3753 | 0.4428 | 0.7742 | 3.7986 | 0.3305 | 0.5228 | 1.4805 | 0.3543 | 0.8318 | 1.6492 | 0.3597 |
4-Hydroxyproline | 1.0080 | 0.1117 | 0.7196 | 1.0225 | 0.1208 | 0.7792 | 3.1513 | 0.4343 | 1.0814 | 3.3667 | 0.3033 | 1.0180 |
5-Aminopentanoic acid | 1.2393 | 0.5550 | 0.8992 | 1.0095 | 0.4944 | 0.8194 | 1.6617 | 0.9630 | 1.1169 | 2.0308 | 0.8403 | 0.9489 |
5-Methoxytryptamine | 1.1834 | 0.2258 | 1.7304 | 1.3690 | 0.2529 | 1.3358 | 0.8198 | 0.1356 | 1.7752 | 1.0653 | 0.2093 | 1.9775 |
7-Methylguanine | 1.5995 | 0.3813 | 0.8625 | 1.4664 | 1.1992 | 0.7854 | 1.4703 | 0.6961 | 0.6588 | 1.6719 | 0.5230 | 0.6909 |
Acetoacetic acid | 1.0703 | 0.8717 | 1.0694 | 1.1340 | 0.8970 | 0.9873 | 1.0436 | 0.8937 | 1.0433 | 1.0967 | 0.9079 | 1.0106 |
Acetylglycine | 1.0372 | 0.3506 | 0.8937 | 0.9460 | 0.5027 | 0.9144 | 1.6690 | 0.7592 | 1.8314 | 1.6226 | 0.6084 | 1.5309 |
Adenine | 0.7492 | 0.0760 | 1.9852 | 0.6001 | 0.0855 | 2.1571 | 0.6020 | 0.0928 | 2.5645 | 0.6587 | 0.0792 | 2.3898 |
Adenosine | 0.0393 | 0.0060 | 1.4760 | 0.0521 | 0.0165 | 2.2340 | 0.0956 | 0.0125 | 4.1800 | 0.1287 | 0.0150 | 4.3725 |
Adipic acid | 1.0476 | 0.6429 | 1.2720 | 0.9261 | 0.9050 | 1.1287 | 1.3045 | 0.8296 | 1.2886 | 0.8494 | 0.7552 | 1.0842 |
Allantoin | 1.7599 | 0.0628 | 0.9904 | 1.4847 | 0.2394 | 0.7797 | 2.2827 | 0.3066 | 1.1549 | 2.2590 | 0.2429 | 0.9196 |
Alpha-Hydroxyisobutyric acid | 0.6843 | 0.2402 | 0.5514 | 0.7110 | 0.2838 | 0.5109 | 2.5173 | 1.0419 | 1.7974 | 2.4508 | 1.0121 | 1.5842 |
Aminoadipic acid | 0.8120 | 0.8016 | 0.6063 | 0.8352 | 1.2899 | 0.5981 | 0.8412 | 2.1743 | 0.5421 | 0.9770 | 2.3909 | 0.5391 |
Arachidonic acid | 0.6832 | 0.5106 | 1.9171 | 0.7585 | 0.5820 | 1.7552 | 0.6954 | 0.6196 | 1.6758 | 0.7561 | 0.5524 | 1.2806 |
Azelaic acid | 0.8876 | 0.6753 | 1.4927 | 0.8514 | 0.8740 | 1.0646 | 1.0451 | 0.9827 | 0.9982 | 1.0248 | 0.9793 | 1.1759 |
Benzoic acid | 0.8243 | 1.2149 | 0.8453 | 0.8999 | 1.1231 | 1.0309 | 0.9284 | 1.1866 | 0.7247 | 0.9807 | 1.2352 | 0.9648 |
Beta-Alanine | 0.9828 | 0.0590 | 0.1756 | 1.0880 | 0.0885 | 0.1464 | 5.1299 | 0.1970 | 0.3851 | 5.0211 | 0.1448 | 0.3153 |
Beta-Glycerophosphoric acid | 0.8545 | 0.2691 | 1.3455 | 0.8490 | 0.3492 | 1.5328 | 1.2016 | 0.3309 | 1.7347 | 1.8384 | 0.3104 | 1.6983 |
Cadaverine | 0.9975 | 0.0950 | 1.2548 | 0.9536 | 0.1829 | 1.0087 | 2.0863 | 0.1741 | 1.8344 | 2.5347 | 0.3178 | 1.3244 |
Capric acid | 0.8714 | 0.9195 | 1.0693 | 0.9117 | 0.9664 | 1.1453 | 0.9278 | 1.0667 | 0.9812 | 1.0673 | 0.9686 | 1.1035 |
Caprylic acid | 0.8421 | 1.0735 | 0.8704 | 0.9393 | 1.2388 | 0.9887 | 0.8465 | 1.2198 | 0.7971 | 0.9506 | 1.2347 | 0.9403 |
Cholesterol | 1.3507 | 0.2255 | 1.5844 | 1.1154 | 0.3046 | 1.5922 | 1.1601 | 0.3014 | 1.4615 | 1.0302 | 0.3803 | 1.5154 |
cis-Aconitic acid | 1.0219 | 0.3612 | 0.8917 | 1.3879 | 0.5982 | 1.3967 | 1.4477 | 1.0185 | 1.2215 | 1.1489 | 0.7700 | 0.8784 |
Citramalic acid | 2.1977 | 0.2115 | 0.7000 | 2.5919 | 0.3685 | 0.7000 | 1.5030 | 0.4474 | 0.7246 | 1.6990 | 0.2809 | 0.6934 |
Citric acid | 1.0198 | 0.4961 | 0.7472 | 1.2521 | 0.7179 | 1.3220 | 1.5212 | 1.0588 | 1.1922 | 1.0991 | 0.9691 | 0.7785 |
Creatinine | 2.3497 | 0.1123 | 0.7661 | 2.2508 | 0.0793 | 0.8346 | 2.0941 | 0.1264 | 0.7706 | 2.1926 | 0.0751 | 0.6785 |
D-Alpha-aminobutyric acid | 1.5719 | 0.2527 | 1.1844 | 2.5852 | 0.4230 | 1.5595 | 1.0296 | 0.2106 | 0.6583 | 1.1580 | 0.1890 | 0.6648 |
D-Arabitol | 1.3331 | 0.0778 | 1.6521 | 1.0139 | 0.1169 | 1.5408 | 1.4216 | 0.1398 | 1.8044 | 1.3686 | 0.1277 | 1.6446 |
D-Fucose | 1.1716 | 0.5421 | 1.2370 | 0.8853 | 0.6705 | 0.9830 | 1.4686 | 1.0631 | 0.9101 | 1.4142 | 0.8789 | 1.0834 |
D-Galactose | 1.3375 | 0.7350 | 0.8483 | 0.9222 | 0.8769 | 0.4017 | 1.0805 | 1.7898 | 0.6475 | 1.2571 | 2.1778 | 0.4888 |
Dihydrouracil | 0.8036 | 0.4681 | 1.1073 | 0.9065 | 0.6092 | 0.9701 | 1.5682 | 1.2622 | 1.2625 | 1.4026 | 0.9215 | 1.2171 |
Dimethylglycine | 1.0100 | 0.6360 | 0.8847 | 0.9343 | 1.1802 | 0.9019 | 1.4050 | 0.9355 | 1.0321 | 1.2983 | 0.9901 | 0.9587 |
D-Leucic acid | 1.7071 | 0.0845 | 1.0503 | 1.4121 | 0.0882 | 1.0436 | 2.9242 | 0.2708 | 0.8519 | 2.3108 | 0.0952 | 0.7220 |
D-Mannose | 1.3440 | 0.7654 | 0.8375 | 0.9732 | 0.9206 | 0.4086 | 1.0941 | 1.7175 | 0.6425 | 1.1854 | 2.1220 | 0.4924 |
Docosahexaenoic acid | 1.0669 | 0.1670 | 2.0020 | 1.0660 | 0.1550 | 1.9000 | 1.0646 | 0.2110 | 1.6471 | 1.0773 | 0.2003 | 1.3024 |
Dodecanoic acid | 0.8533 | 0.7629 | 1.2884 | 0.7840 | 0.8083 | 1.1108 | 1.0635 | 1.1162 | 1.1380 | 1.1176 | 0.9777 | 1.1230 |
Dopamine | 0.3181 | 0.2181 | 0.4897 | 0.5733 | 5.1997 | 0.1894 | 0.1688 | 0.9314 | 0.5847 | 0.6326 | 1.1344 | 0.3503 |
D-Sedoheptulose 7-phosphate | 0.1279 | 0.5460 | 2.4194 | 0.1693 | 0.8247 | 1.8464 | 0.3456 | 0.6270 | 2.2416 | 0.5495 | 0.9644 | 1.0563 |
D-Tagatose | 1.4070 | 0.4858 | 0.9703 | 1.4450 | 0.9005 | 0.8853 | 1.2257 | 0.9815 | 0.8617 | 1.1976 | 0.9225 | 0.8037 |
D-Threitol | 1.2834 | 0.3555 | 1.4160 | 1.3329 | 0.4851 | 1.1732 | 1.5102 | 0.8586 | 1.0546 | 1.3644 | 0.4408 | 0.8321 |
D-Xylitol | 1.2381 | 0.1739 | 1.8968 | 1.0466 | 0.2572 | 1.2919 | 1.3160 | 0.3650 | 1.9081 | 1.2659 | 0.3751 | 1.0413 |
D-Xylose | 2.1652 | 0.3710 | 0.6298 | 2.4710 | 0.3226 | 0.4988 | 2.0304 | 0.6793 | 0.5552 | 1.6649 | 0.3494 | 0.5478 |
Eicosapentaenoic acid | 0.7474 | 0.4824 | 1.8483 | 0.8100 | 0.5459 | 1.7088 | 0.7949 | 0.5967 | 1.6313 | 0.8854 | 0.5340 | 1.2566 |
Elaidic acid | 0.6568 | 1.4870 | 1.2725 | 0.8034 | 1.2805 | 0.9628 | 0.5873 | 1.2013 | 0.9436 | 0.5862 | 1.1952 | 0.7208 |
Ethanolamine | 1.0619 | 0.3205 | 1.4152 | 1.2303 | 0.4844 | 1.5469 | 1.2347 | 0.3496 | 1.4120 | 1.3381 | 0.2965 | 1.2922 |
Ethylmalonic acid | 1.3111 | 0.8131 | 0.9935 | 1.2560 | 0.8172 | 0.8045 | 1.3655 | 0.9540 | 0.9286 | 1.3618 | 0.8759 | 0.6585 |
Fructose 1-phosphate | 0.8397 | 0.2291 | 1.5331 | 0.6482 | 0.2834 | 0.8168 | 0.9692 | 0.2412 | 0.9238 | 5.5099 | 0.1882 | 0.6252 |
Fructose 6-phosphate | 0.1826 | 0.1663 | 1.5897 | 0.2465 | 0.0380 | 0.7641 | 0.7037 | 0.0546 | 0.7001 | 8.0857 | 0.0735 | 0.6765 |
Fumaric acid | 1.4500 | 0.0778 | 1.5238 | 1.3020 | 0.0940 | 1.3817 | 1.3151 | 0.1024 | 1.7219 | 1.3787 | 0.1059 | 1.8098 |
Galacturonic acid | 0.9043 | 0.3920 | 0.7601 | 0.6651 | 0.5540 | 0.5741 | 1.5118 | 2.0674 | 1.0509 | 1.9755 | 1.7239 | 0.8362 |
Gamma-Aminobutyric acid | 0.6793 | 0.0316 | 2.2899 | 0.4668 | 0.0686 | 2.0440 | 0.8354 | 0.1274 | 2.5243 | 0.7688 | 0.0942 | 2.1509 |
Gluconic acid | 0.9651 | 0.5716 | 1.4061 | 0.8204 | 0.9420 | 0.8248 | 1.0085 | 1.0848 | 1.1181 | 1.4379 | 1.0802 | 0.9684 |
Glucose 6-phosphate | 0.1969 | 0.2016 | 1.5413 | 0.2318 | 0.0493 | 0.7237 | 1.0194 | 0.0613 | 0.6683 | 7.9109 | 0.1114 | 0.5912 |
Glutamate, gamma-methyl ester | 0.9054 | 0.3429 | 1.6681 | 0.9405 | 0.3072 | 1.9130 | 1.0954 | 0.1487 | 1.5314 | 1.3270 | 0.1460 | 1.5805 |
Glutaric acid | 1.0515 | 0.6673 | 1.0853 | 1.0241 | 0.7960 | 1.0227 | 1.2313 | 1.1033 | 0.9226 | 1.1735 | 1.1365 | 0.9738 |
Glutathione | 1.7752 | 0.1451 | 0.8787 | 1.8262 | 0.3172 | 0.9520 | 1.8546 | 0.1489 | 1.3343 | 1.9901 | 0.2430 | 0.8781 |
Glyceraldehyde | 1.0283 | 0.9811 | 1.0291 | 1.0148 | 0.9544 | 0.9988 | 1.0316 | 0.9512 | 0.9999 | 1.0622 | 0.9954 | 0.9657 |
Glyceric acid | 0.8904 | 0.6070 | 0.7326 | 1.0498 | 1.0933 | 0.8053 | 1.1982 | 0.9734 | 0.7447 | 2.5468 | 0.8681 | 0.8174 |
Glycerol | 1.3217 | 0.8289 | 0.9860 | 1.2538 | 0.8390 | 0.7885 | 1.3516 | 0.9639 | 0.8955 | 1.3616 | 0.9175 | 0.6235 |
Glycerol 3-phosphate | 0.4864 | 0.1687 | 1.6144 | 0.3708 | 0.1983 | 1.6255 | 1.2164 | 0.1587 | 2.2734 | 1.9277 | 0.2199 | 2.2867 |
Glycine | 1.7971 | 0.2124 | 0.6153 | 1.7167 | 0.2603 | 0.5836 | 2.7952 | 0.3052 | 0.6361 | 2.9499 | 0.2666 | 0.5781 |
Glycolic acid | 1.2809 | 0.5425 | 1.1588 | 1.3559 | 0.7782 | 1.1552 | 1.1623 | 0.7872 | 1.0191 | 1.1199 | 0.6628 | 0.9382 |
Glycyl-glycine | 1.2166 | 0.2958 | 1.5919 | 0.9129 | 0.4137 | 1.3673 | 1.3368 | 0.5000 | 1.7893 | 1.1314 | 0.5316 | 1.0807 |
Guanine | 0.9489 | 0.2202 | 1.2098 | 0.9390 | 0.5402 | 1.3201 | 1.0989 | 2.2425 | 1.2652 | 0.8733 | 0.2936 | 1.3947 |
Guanosine | 0.1769 | 0.2327 | 1.9718 | 0.2409 | 0.7021 | 1.8510 | 0.3978 | 0.5600 | 2.8470 | 0.2593 | 0.4340 | 2.3811 |
Heptadecanoic acid | 0.7367 | 0.8421 | 1.3188 | 0.8064 | 0.9498 | 1.3139 | 0.8539 | 0.8616 | 1.1964 | 0.8736 | 1.0411 | 1.1131 |
Histamine | 1.1094 | 0.8003 | 0.1930 | 2.1512 | 1.6777 | 0.1434 | 1.5425 | 0.6586 | 0.2115 | 1.7741 | 1.6413 | 0.1248 |
Homocysteine | 1.2022 | 0.1767 | 2.0151 | 0.8935 | 0.3044 | 1.3594 | 1.1377 | 0.4910 | 1.1057 | 1.8672 | 0.4235 | 1.1507 |
Hydroxylamine | 1.0774 | 0.7955 | 1.1443 | 1.1557 | 0.8193 | 0.9413 | 1.1544 | 0.8199 | 0.9819 | 1.4597 | 0.8332 | 0.9075 |
Hydroxyphenyllactic acid | 1.4930 | 0.1200 | 1.4792 | 1.1128 | 0.2129 | 1.5514 | 1.3482 | 0.2274 | 1.3463 | 1.6183 | 0.2240 | 1.4246 |
Hydroxypropionic acid | 0.8963 | 0.7552 | 1.1501 | 0.9262 | 0.8830 | 1.1651 | 1.0426 | 0.9698 | 1.2194 | 1.0181 | 0.8305 | 1.2027 |
Hypotaurine | 0.9653 | 0.0783 | 1.2847 | 0.9472 | 0.1580 | 1.0265 | 2.0936 | 0.1522 | 1.9169 | 2.5144 | 0.2807 | 1.3545 |
Hypoxanthine | 0.4259 | 0.2079 | 2.2239 | 0.5161 | 0.5020 | 2.0170 | 0.7160 | 0.3990 | 2.3144 | 0.5079 | 0.3636 | 1.6303 |
Inosine | 0.3278 | 0.1123 | 2.5514 | 0.4167 | 0.2582 | 2.1122 | 0.8767 | 0.3203 | 2.4099 | 0.6381 | 0.2064 | 1.6501 |
Isocitric acid | 0.7477 | 0.5545 | 1.1692 | 0.7202 | 0.7537 | 1.5002 | 1.0527 | 1.5300 | 1.4375 | 0.6377 | 1.1322 | 0.8851 |
Isomaltose | 2.2261 | 0.2044 | 0.2541 | 1.5354 | 0.2194 | 0.2429 | 3.3756 | 0.1859 | 0.2455 | 4.1730 | 0.1540 | 0.2636 |
Itaconic acid | 1.4560 | 0.0950 | 1.4211 | 1.3605 | 0.1204 | 1.2762 | 1.4650 | 0.1519 | 1.5659 | 1.5099 | 0.2751 | 1.6231 |
L-2-Hydroxyglutaric acid | 0.5549 | 0.0286 | 2.7588 | 0.5238 | 0.0558 | 2.2372 | 0.6590 | 0.1488 | 2.6176 | 0.4638 | 0.0418 | 1.6987 |
Labelled compound_Taurine | 1.5931 | 0.0986 | 1.2768 | 1.5258 | 0.1211 | 1.2856 | 1.7151 | 0.1637 | 1.3747 | 1.6534 | 0.1470 | 1.3221 |
Lactitol | 2.2053 | 0.1823 | 1.2986 | 1.3785 | 0.2377 | 0.8411 | 1.9376 | 0.3094 | 0.9239 | 2.0731 | 0.3404 | 0.6401 |
L-Alanine | 1.4612 | 0.1291 | 1.3171 | 1.3628 | 0.1585 | 1.2117 | 1.8224 | 0.2286 | 1.3036 | 1.8039 | 0.1897 | 1.3734 |
L-Arginine | 1.1119 | 0.2466 | 1.5120 | 1.0481 | 0.2976 | 1.4435 | 1.4292 | 0.4125 | 1.4551 | 1.5333 | 0.3873 | 1.3332 |
L-Asparagine | 1.8175 | 0.0887 | 1.0266 | 1.7848 | 0.0859 | 1.0279 | 2.1981 | 0.1026 | 1.0505 | 2.3391 | 0.0857 | 0.8007 |
L-Aspartic acid | 0.8162 | 0.1724 | 2.0166 | 0.6231 | 0.3962 | 2.0922 | 0.4624 | 0.2480 | 2.1447 | 0.3826 | 0.2967 | 2.1679 |
L-Cystathionine | 0.9570 | 0.1624 | 1.2824 | 0.9236 | 0.3939 | 0.9326 | 2.1065 | 0.4667 | 1.3778 | 2.2566 | 0.6382 | 1.1679 |
L-Cysteine | 0.8217 | 0.5813 | 1.0175 | 0.7411 | 1.0803 | 1.1072 | 1.1679 | 0.9417 | 1.2365 | 1.0656 | 1.1850 | 1.2415 |
L-Erythrulose | 0.6290 | 0.2212 | 2.5042 | 0.4958 | 0.2874 | 1.9811 | 0.6051 | 0.3082 | 2.3424 | 0.5591 | 0.2496 | 1.6414 |
L-Glutamic acid | 0.5667 | 0.1310 | 2.3134 | 0.4763 | 0.2453 | 2.2983 | 0.3837 | 0.1858 | 2.3956 | 0.3786 | 0.1800 | 2.2375 |
L-Glutamine | 0.7578 | 0.0812 | 2.6654 | 0.7170 | 0.1058 | 1.8883 | 0.6999 | 0.1277 | 2.2915 | 0.7805 | 0.1599 | 1.5914 |
L-Histidine | 1.7355 | 0.0218 | 1.3372 | 1.0751 | 0.0351 | 1.0207 | 2.4835 | 0.0121 | 1.5923 | 2.0765 | 0.1483 | 0.7419 |
L-Homoserine | 1.6468 | 0.1205 | 1.1806 | 1.5081 | 0.1381 | 1.2811 | 1.4940 | 0.1626 | 1.5453 | 1.4512 | 0.1260 | 1.6409 |
Linoleic acid | 0.3935 | 1.1853 | 1.7118 | 0.4239 | 1.0370 | 1.2124 | 0.4559 | 1.2811 | 1.4676 | 0.4369 | 1.2670 | 0.9707 |
L-Isoleucine | 1.2732 | 0.3201 | 1.1433 | 1.2798 | 0.4295 | 0.9911 | 1.6925 | 0.5130 | 1.2294 | 1.8477 | 0.4446 | 1.2317 |
L-Kynurenine | 1.1053 | 1.4835 | 1.0965 | 0.7564 | 2.3843 | 0.7817 | 0.7845 | 0.2309 | 0.7286 | 0.8310 | 0.4417 | 0.5204 |
L-Lactic acid | 2.0227 | 0.1537 | 0.9829 | 1.9524 | 0.1721 | 0.8416 | 2.0107 | 0.2816 | 0.9966 | 1.8743 | 0.1931 | 0.8700 |
L-Leucine | 1.0220 | 0.4498 | 1.2366 | 1.0232 | 0.5929 | 0.9986 | 1.4937 | 0.6987 | 1.3697 | 1.5566 | 0.6491 | 1.2659 |
L-Lysine | 1.4159 | 0.1927 | 1.2635 | 1.2542 | 0.1994 | 1.2237 | 1.8256 | 0.3009 | 1.2317 | 1.9888 | 0.2960 | 1.1865 |
L-Methionine | 1.5741 | 0.3706 | 1.0056 | 1.6560 | 0.4594 | 0.9108 | 1.5923 | 0.4100 | 1.0830 | 1.7596 | 0.4775 | 0.9511 |
L-Phenylalanine | 1.3272 | 0.3420 | 1.0995 | 1.3188 | 0.5446 | 0.9744 | 1.5941 | 0.5557 | 1.1711 | 1.7675 | 0.5547 | 1.0694 |
L-Proline | 1.3852 | 0.2952 | 0.8063 | 1.4499 | 0.4254 | 0.7649 | 2.2265 | 0.6237 | 0.9077 | 2.2440 | 0.5365 | 0.9231 |
L-Serine | 1.1304 | 0.2354 | 1.2240 | 1.1929 | 0.3125 | 1.2779 | 1.7503 | 0.4484 | 1.3889 | 1.6527 | 0.4129 | 1.3325 |
L-Sorbose | 1.1830 | 0.2907 | 0.8843 | 1.1434 | 0.4104 | 0.5396 | 1.2055 | 1.9789 | 0.5284 | 2.6253 | 1.6938 | 0.3829 |
L-Threonine | 1.1451 | 0.2023 | 1.2144 | 1.1612 | 0.2764 | 1.2567 | 1.6927 | 0.3620 | 1.5083 | 1.7942 | 0.3702 | 1.4366 |
L-Tryptophan | 1.4814 | 0.1768 | 1.6935 | 1.3994 | 0.4047 | 1.2183 | 1.2759 | 0.3221 | 1.2070 | 1.5690 | 0.4466 | 0.8276 |
L-Tyrosine | 1.5330 | 0.2722 | 1.0854 | 1.4743 | 0.4539 | 0.8648 | 1.7299 | 0.4826 | 1.0899 | 1.9068 | 0.5219 | 0.9548 |
L-Valine | 1.3689 | 0.3298 | 0.9889 | 1.3527 | 0.4305 | 0.8684 | 1.8765 | 0.5835 | 1.1081 | 1.9297 | 0.5317 | 1.1094 |
Maleic acid | 1.5545 | 0.2681 | 1.3832 | 1.2762 | 0.3136 | 1.1167 | 1.4262 | 0.2992 | 1.5032 | 1.4290 | 0.2707 | 1.4193 |
Malic acid | 1.3875 | 0.1067 | 1.7179 | 1.1154 | 0.1357 | 1.4588 | 1.1695 | 0.1471 | 1.8968 | 1.1222 | 0.1303 | 1.8017 |
Maltitol | 1.7152 | 0.0345 | 1.3849 | 1.0692 | 0.0509 | 1.2970 | 1.6982 | 0.0428 | 1.8141 | 1.3253 | 0.0539 | 1.5860 |
Mannose 6-phosphate | 0.4740 | 0.1770 | 1.3634 | 0.3612 | 0.0530 | 0.5988 | 1.0761 | 0.0844 | 0.6022 | 7.9368 | 0.1069 | 0.5197 |
Mesaconic acid | 2.6559 | 0.0761 | 0.3283 | 3.5419 | 0.0762 | 0.3076 | 2.2184 | 0.1130 | 0.3001 | 2.2701 | 0.1075 | 0.2650 |
Methylmalonic acid | 0.7248 | 0.4369 | 1.7090 | 0.5662 | 0.5098 | 1.8382 | 0.5289 | 0.4804 | 2.2776 | 0.4035 | 0.5393 | 1.9467 |
Methylsuccinic acid | 0.7036 | 0.2576 | 2.1051 | 0.7588 | 0.3061 | 2.0358 | 0.5709 | 0.3749 | 1.8763 | 0.6162 | 0.3956 | 1.8046 |
MG(18:0e/0:0/0:0) | 0.8491 | 0.6075 | 1.4351 | 0.8888 | 0.6934 | 1.4724 | 0.9715 | 0.7575 | 1.2617 | 0.9880 | 0.6915 | 1.3415 |
myo-Inositol | 0.6923 | 1.5747 | 0.6598 | 0.7487 | 1.6235 | 0.6722 | 0.5233 | 1.7508 | 0.6554 | 0.6044 | 1.7942 | 0.5914 |
N-Acetyl-D-glucosamine | 0.6380 | 1.5493 | 0.6061 | 0.6831 | 1.7070 | 0.6211 | 0.4902 | 1.8905 | 0.6054 | 0.5531 | 2.0545 | 0.5416 |
N-Acetylgalactosamine | 0.6242 | 1.5720 | 0.5921 | 0.6743 | 1.7303 | 0.6037 | 0.4720 | 1.9241 | 0.5881 | 0.5396 | 2.0888 | 0.5305 |
N-Acetylglutamine | 1.3540 | 0.2489 | 1.2335 | 1.2447 | 0.2444 | 1.1665 | 1.8340 | 0.4347 | 1.1706 | 1.8441 | 0.3919 | 1.2245 |
N-Acetyl-L-alanine | 0.8908 | 0.4394 | 1.4898 | 0.9033 | 0.5977 | 1.3771 | 1.1454 | 0.5933 | 1.4571 | 1.2104 | 0.5804 | 1.4191 |
N-Acetyl-L-alanine_2 | 1.0274 | 0.4463 | 1.2336 | 1.0291 | 0.5880 | 0.9953 | 1.5019 | 0.6935 | 1.3653 | 1.5734 | 0.6439 | 1.2632 |
N-Acetyl-L-aspartic acid | 2.0822 | 0.4038 | 0.7729 | 1.8536 | 0.4136 | 0.7446 | 1.6227 | 0.9264 | 0.7152 | 1.0928 | 0.9248 | 0.7240 |
N-Acetylserine | 1.2885 | 0.2082 | 0.8047 | 1.3313 | 0.3621 | 0.8021 | 2.5382 | 0.5811 | 0.9191 | 2.5190 | 0.4724 | 0.8794 |
N-Formyl-L-Methionine | 1.5566 | 0.1113 | 1.3010 | 1.5039 | 0.1375 | 1.2934 | 1.6532 | 0.1842 | 1.3951 | 1.6315 | 0.1645 | 1.3314 |
Niacinamide | 1.1217 | 0.0888 | 1.9007 | 0.9814 | 0.1231 | 1.7730 | 1.0747 | 0.1726 | 2.0293 | 0.9017 | 0.1392 | 1.7434 |
Nicotinic acid | 1.1398 | 0.4827 | 1.0094 | 1.2578 | 0.6021 | 1.0647 | 1.2656 | 0.9216 | 0.9375 | 1.8215 | 0.7562 | 1.0131 |
Norvaline | 1.0736 | 0.3781 | 0.9859 | 1.5331 | 0.4630 | 1.0038 | 1.5157 | 0.4865 | 1.0650 | 2.1195 | 0.5663 | 1.1559 |
Oleic acid | 0.4278 | 1.6068 | 1.4045 | 0.5186 | 1.3951 | 0.9894 | 0.4218 | 1.3388 | 1.0644 | 0.3988 | 1.4264 | 0.6796 |
O-Phosphoethanolamine | 0.5269 | 0.6442 | 1.2704 | 0.4899 | 1.3179 | 1.4956 | 0.5195 | 1.1854 | 1.2715 | 0.5168 | 1.3566 | 1.2500 |
Ornithine | 1.2493 | 0.1846 | 1.4363 | 1.0611 | 0.2150 | 1.5966 | 1.4562 | 0.2986 | 1.5822 | 1.4343 | 0.2562 | 1.4199 |
Oxalacetic acid | 0.8507 | 0.1347 | 1.9038 | 0.6917 | 0.1845 | 1.7297 | 1.0212 | 0.3535 | 2.0421 | 1.1344 | 0.2564 | 1.8864 |
Oxalic acid | 0.9101 | 0.6324 | 1.1815 | 0.9523 | 0.9363 | 1.1727 | 1.0767 | 0.7557 | 1.2012 | 1.1861 | 0.8473 | 1.1938 |
Palmitic acid | 0.9353 | 0.8129 | 1.3187 | 1.0036 | 0.8733 | 1.1356 | 0.9930 | 0.8670 | 1.1084 | 1.0384 | 0.9095 | 0.9576 |
Palmitoleic acid | 0.6903 | 2.0400 | 0.5251 | 0.9630 | 1.5884 | 0.3716 | 0.7036 | 1.8731 | 0.3681 | 0.7297 | 1.7471 | 0.2748 |
Pantothenic acid | 0.9591 | 0.4146 | 2.2317 | 0.8643 | 0.5365 | 2.0687 | 0.6400 | 0.4223 | 1.0698 | 0.6419 | 0.4156 | 1.1765 |
Pelargonic acid | 0.8300 | 1.1663 | 0.8922 | 0.9031 | 1.1801 | 1.0401 | 0.9007 | 1.2380 | 0.7585 | 0.9039 | 1.1767 | 0.9274 |
Phenylacetic acid | 1.1697 | 0.7193 | 1.2279 | 0.9755 | 1.1360 | 1.0342 | 0.9532 | 1.0258 | 0.8631 | 0.8443 | 1.0619 | 0.8839 |
Phenyllactic acid | 1.2639 | 0.4008 | 0.9387 | 1.2473 | 0.5583 | 0.9972 | 1.9240 | 0.6964 | 0.9604 | 1.9105 | 0.6042 | 0.8775 |
Phosphoenolpyruvic acid | 1.1518 | 1.0659 | 0.1604 | 1.1270 | 1.7534 | 0.1581 | 0.8243 | 1.0602 | 0.1506 | 2.9540 | 1.7492 | 0.1265 |
p-Hydroxyphenylacetic acid | 1.2504 | 0.4850 | 0.9243 | 1.3414 | 0.8307 | 0.8305 | 1.3303 | 1.0846 | 0.8659 | 1.4032 | 0.8833 | 1.0234 |
Pimelic acid | 0.9047 | 0.7394 | 1.5697 | 0.9296 | 0.8544 | 1.0893 | 1.1276 | 0.7805 | 1.1988 | 1.0402 | 0.7559 | 0.9673 |
p-Octopamine | 0.8429 | 0.1127 | 1.9073 | 0.8021 | 0.1677 | 1.5008 | 1.4853 | 0.3150 | 1.8154 | 1.7588 | 0.2568 | 1.3367 |
Psicose_2 | 1.1295 | 0.2774 | 0.9305 | 1.0203 | 0.3989 | 0.5530 | 1.1863 | 2.0263 | 0.5615 | 2.6613 | 1.7713 | 0.3953 |
Putrescine | 2.2109 | 0.2017 | 0.6132 | 2.1226 | 0.2856 | 0.4858 | 2.8483 | 0.3077 | 0.5123 | 2.2011 | 0.3025 | 0.4284 |
Pyroglutamic acid | 0.9257 | 0.1042 | 1.7945 | 0.8670 | 0.1398 | 2.1824 | 0.9703 | 0.1689 | 1.8574 | 0.7940 | 0.1541 | 1.9570 |
Pyruvic acid | 1.5399 | 0.3394 | 0.9680 | 1.0101 | 0.5077 | 0.7805 | 2.0399 | 0.3514 | 1.0964 | 2.8845 | 0.3668 | 0.7075 |
Rhamnose | 1.2467 | 0.5319 | 1.1395 | 0.8404 | 0.6537 | 0.9322 | 1.4413 | 1.2069 | 1.1638 | 1.2749 | 1.0085 | 0.9262 |
Ribitol | 2.1257 | 0.1302 | 1.0669 | 1.7359 | 0.2585 | 0.8880 | 1.8760 | 0.3469 | 1.0610 | 1.6974 | 0.2805 | 0.8468 |
(S)-3-Hydroxyisobutyric acid | 1.6558 | 0.4390 | 1.5070 | 1.4922 | 0.5828 | 0.9388 | 1.0131 | 0.4622 | 1.1079 | 1.1730 | 0.5319 | 1.0770 |
Sarcosine | 1.3922 | 0.4562 | 0.8577 | 1.5678 | 0.5264 | 0.8806 | 1.9014 | 0.7043 | 0.8659 | 1.7717 | 0.5247 | 0.8759 |
Spermidine | 0.8907 | 0.4184 | 1.1414 | 0.8734 | 0.8781 | 1.0612 | 0.9007 | 1.7278 | 1.0515 | 0.8605 | 1.4257 | 1.0555 |
Stearic acid | 0.6172 | 0.7031 | 1.5317 | 0.6573 | 0.8730 | 1.5502 | 0.7348 | 0.7683 | 1.4473 | 0.7991 | 0.8141 | 1.3697 |
Succinic acid | 1.5979 | 0.1912 | 0.6928 | 1.5921 | 0.2010 | 0.8954 | 1.7519 | 0.3060 | 1.4348 | 2.0139 | 0.2846 | 1.6706 |
Sucrose | 1.2961 | 0.4192 | 2.0728 | 0.4403 | 0.5841 | 1.8266 | 1.0715 | 1.0314 | 0.4828 | 1.3388 | 0.7251 | 0.4329 |
Threonic acid | 0.7427 | 0.6305 | 1.1195 | 0.6540 | 1.0965 | 1.2047 | 0.8313 | 1.0976 | 1.3141 | 0.7691 | 1.2696 | 1.3797 |
Thymine | 0.8990 | 0.3324 | 1.2954 | 1.1180 | 0.6272 | 1.3020 | 1.0529 | 0.5947 | 1.5057 | 1.4990 | 0.4642 | 1.4738 |
Trehalose | 2.0729 | 0.2286 | 1.2924 | 1.3405 | 0.3000 | 0.8525 | 1.8429 | 0.3766 | 0.8743 | 2.0771 | 0.4349 | 0.6568 |
Triethanolamine | 1.0608 | 0.7583 | 1.0825 | 1.0229 | 0.9394 | 1.0641 | 1.1415 | 0.8169 | 1.0668 | 1.3035 | 0.8190 | 0.9645 |
Tryptamine | 1.0659 | 0.3595 | 2.1800 | 0.9006 | 0.4707 | 1.9896 | 0.7920 | 0.3700 | 1.0995 | 0.7829 | 0.3714 | 1.1523 |
Tyramine | 1.4062 | 0.1958 | 1.2636 | 1.2552 | 0.2036 | 1.2322 | 1.7998 | 0.3107 | 1.2406 | 1.9687 | 0.3034 | 1.1917 |
Uracil | 0.3693 | 0.6123 | 1.8488 | 0.3493 | 0.8725 | 1.4392 | 0.5568 | 0.6599 | 2.2631 | 0.6550 | 0.6472 | 1.7414 |
Urea | 1.3469 | 0.3855 | 0.9284 | 1.2709 | 0.5118 | 0.8835 | 1.7125 | 0.8297 | 1.1106 | 1.7419 | 0.6881 | 1.0497 |
Uric acid | 1.0010 | 0.6187 | 0.5236 | 1.0278 | 1.3073 | 0.4698 | 1.6391 | 1.3108 | 0.7009 | 1.7963 | 1.4718 | 0.5985 |
Uridine | 0.4551 | 0.3105 | 1.8226 | 0.5724 | 0.4713 | 1.8280 | 0.8555 | 0.6819 | 1.7388 | 0.6756 | 0.6779 | 1.9576 |
Xanthine | 0.4685 | 0.2792 | 1.8027 | 0.6026 | 0.8405 | 1.6526 | 0.7533 | 0.6481 | 2.0748 | 0.6129 | 0.6795 | 1.5218 |
Xanthosine | 0.3534 | 0.4803 | 1.4047 | 0.3920 | 0.8406 | 1.3011 | 0.6416 | 2.0463 | 1.7928 | 0.5961 | 0.9221 | 1.5627 |
Factors:
F1 | Sex:Female | Genotype:ERalpha-knockout | Tissue:Skeletal muscle |
F2 | Sex:Female | Genotype:ERalpha-knockout | Tissue:Subcutaneous fat |
F3 | Sex:Female | Genotype:ERalpha-knockout | Tissue:Ventricles |
F4 | Sex:Female | Genotype:Floxed Control | Tissue:Skeletal muscle |
F5 | Sex:Female | Genotype:Floxed Control | Tissue:Subcutaneous fat |
F6 | Sex:Female | Genotype:Floxed Control | Tissue:Ventricles |
F7 | Sex:Male | Genotype:ERalpha-knockout | Tissue:Skeletal muscle |
F8 | Sex:Male | Genotype:ERalpha-knockout | Tissue:Subcutaneous fat |
F9 | Sex:Male | Genotype:ERalpha-knockout | Tissue:Ventricles |
F10 | Sex:Male | Genotype:Floxed Control | Tissue:Skeletal muscle |
F11 | Sex:Male | Genotype:Floxed Control | Tissue:Subcutaneous fat |
F12 | Sex:Male | Genotype:Floxed Control | Tissue:Ventricles |