Data for (Study ST002242)

(Analysis AN003660)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

MetaboliteF1F2F3F4F5F6
1-methyladenosine 0.1302 0.8840 1.0579 0.2452 1.7679 1.9147
1-methylnicotinamide 0.1286 0.5628 1.3513 0.2949 0.7484 2.9140
2/3-phosphoglycerate 0.1442 3.2144 0.5472 0.1890 1.4516 0.4536
2-oxoglutarate 0.0797 1.2955 0.7728 0.1473 1.9547 1.7501
4-hydroxybenzaldehyde 0.0813 0.3903 1.4107 0.2726 0.7237 3.1214
4-hydroxyphenyllactate 0.0814 0.3324 0.5933 0.5423 1.0955 3.3551
4-hydroxyproline 0.2115 0.2410 0.9408 0.6786 0.8652 3.0629
4-imidazolone-5-propanoate 0.0272 0.2447 0.3299 0.3709 1.3315 3.6958
5-hydroxyindoleacetate NA 0.3313 0.7386 0.3091 0.8541 2.7669
7-methylguanine 0.0081 1.4865 0.2254 0.0507 3.4465 0.7828
acetyl-CoA 0.0565 0.3865 1.4627 0.0609 0.7239 3.3095
aconitate 0.1056 0.4328 0.6546 0.2670 1.7968 2.7432
adenosine NA 1.8312 0.1804 NA 1.3865 0.6019
ADP 0.0966 1.8784 0.8230 0.1593 2.1149 0.9278
ADP-ribose 0.0775 2.5360 0.8424 0.0719 2.0844 0.3878
alanine 0.4163 0.6336 1.6781 0.5005 0.7258 2.0457
allantoin 0.2154 0.5161 0.6620 0.5706 0.8935 3.1425
AMP 0.0546 2.5244 0.4178 0.0379 2.6665 0.2988
anserine NA 0.1773 0.7113 NA 0.3241 2.7874
arginine 0.1655 0.7317 1.0490 0.5066 1.1897 2.3575
argininosuccinate 0.1035 0.4748 1.1856 0.4944 0.8405 2.9013
asparagine 0.1662 0.3968 1.0714 0.5534 0.9063 2.9059
aspartate 0.1623 1.2508 1.3572 0.4385 1.2091 1.5821
ATP 0.1487 0.3916 1.4535 0.2724 0.7937 2.9400
beta-alanine 0.2093 0.3377 1.2385 0.4688 0.6208 3.1249
betaine 0.0580 0.5311 0.6007 0.3119 1.2384 3.2599
carnitine 0.1004 0.3987 1.4925 0.2705 0.7730 2.9649
carnitine C16 NA 0.9604 0.2407 NA 2.0933 0.7056
carnitine C18 NA 1.0532 0.1985 NA 2.0526 0.6956
carnitine C2 0.0845 0.2465 0.7053 0.4014 0.8853 3.6769
carnitine C3 0.0986 0.1816 0.9669 0.4501 0.7827 3.5201
carnitine C3-DC 0.1980 1.1116 1.1295 0.2506 1.2429 2.0675
carnitine C4 0.1666 0.2291 2.4492 0.2074 0.2106 2.7371
carnitine C4-OH 0.0286 0.0823 0.4162 0.4784 0.8651 4.1294
carnitine C5-OH 0.1924 0.7645 2.1264 0.2225 0.6170 2.0771
carnosine 0.0832 0.3374 1.0087 0.5184 0.6783 3.3740
CDP-ethanolamine NA 0.3658 1.6089 0.1610 0.3889 2.4754
choline 0.1227 2.7640 0.8753 0.0838 1.3709 0.7833
cinnamate 0.1737 0.6316 0.8283 0.5716 1.3802 2.4146
citicoline 0.1474 0.4182 1.9634 0.3280 0.4859 2.6570
citrate 0.1204 0.4601 0.4308 0.2491 2.4847 2.2549
citrulline 0.0455 0.4900 0.9655 0.1946 1.1158 3.1888
CMP 0.1201 1.1846 1.4653 0.2112 1.1238 1.8950
CMP-N-Acetylneuraminate 0.1700 0.9891 1.5510 0.3568 1.0450 1.8881
creatine 0.1726 0.8360 1.3303 0.4264 1.0773 2.1573
creatinine 0.1971 0.1342 0.8602 0.4639 0.4807 3.8638
cyclic AMP 0.0470 0.8978 1.5292 0.0764 1.5559 1.8936
cysteinylglycine 0.0370 1.0741 0.7798 0.2563 1.5842 2.2686
cytidine 0.1463 0.5029 1.1866 0.2968 0.7100 3.1574
deoxycarnitine 0.0994 0.3602 1.4618 0.2565 0.6208 3.2012
deoxycytidine 0.1174 0.5750 1.4122 0.2933 0.8179 2.7842
deoxyuridine 0.0823 0.0454 0.5545 0.3926 0.4048 4.5203
dihydroxyacetone phosphate 0.1568 0.6306 2.0314 0.4351 0.8429 1.9032
dipalmitoylphosphatidylcholine 0.1409 NA 2.4494 0.0854 NA 1.3243
dissaccharide 1.8927 1.1629 0.0491 1.1749 0.8942 0.8262
dTMP NA 2.1747 0.3117 NA 1.2909 0.2226
epsilon-(gamma-glutamyl)lysine 0.1923 0.5210 2.1840 0.2153 0.6016 2.2859
erythritol 0.1091 NA 0.5554 0.3223 0.5901 3.2004
FAD 0.0178 2.3387 0.5815 0.0295 2.3689 0.6636
fumarate 0.0703 0.5527 1.2501 0.1461 1.6681 2.3128
gamma-glutamylalanine 0.0476 3.5127 0.7520 0.0843 0.6318 0.9716
gamma-glutamylcysteine 0.1080 0.9981 0.7748 0.2992 2.0344 1.7855
gamma-glutamylglutamate 0.0398 1.1512 0.7473 0.1770 1.3139 2.5709
gamma-glutamylglycine 0.0408 0.9564 0.9667 0.1666 1.3483 2.5213
GDP 0.2326 1.0462 1.3536 0.3303 1.0476 1.9897
GDP-fucose 0.1714 1.5980 1.8866 0.1669 0.8550 1.3221
gluconate 0.1029 0.4302 1.3525 0.3308 0.6512 3.1325
glucosamine 6-phosphate 0.2199 1.3164 1.2398 0.5051 1.0942 1.6246
glutamate 0.1661 0.4954 1.6267 0.3979 0.8658 2.4481
glutamine 0.4073 0.7565 2.4064 0.2872 0.5057 1.6369
glutathione reduced 0.0540 1.0734 0.8313 0.2730 1.5486 2.2196
glyceraldehyde 3-phosphate NA 0.6601 0.6093 NA 1.5934 1.1371
glycerol 2-phosphate 0.1752 1.4344 1.4382 0.3052 0.9006 1.7465
glycerol 3-phosphate 0.0544 0.7257 0.9482 0.1902 1.8769 2.2046
glycerophosphocholine 0.1099 1.5870 1.4157 0.2358 0.9806 1.6710
glycine 0.2070 0.3590 1.1771 0.4376 0.5828 3.2366
GMP 0.0752 2.1316 1.1492 0.0735 1.5272 1.0432
guanidinoacetate 0.1267 0.7213 0.7507 0.5311 0.6726 3.1977
guanine 0.3161 1.8375 0.7630 0.5736 1.3205 1.1893
guanosine 0.0234 2.0496 1.2747 0.0102 0.8721 1.7700
hexitol 0.1012 0.1272 1.2929 0.2532 0.1975 4.0279
hexose phosphate 0.0952 1.9079 1.2290 0.1071 1.2653 1.3956
histidine 0.1480 0.4762 1.0010 0.6023 0.9644 2.8081
homoarginine 0.0773 0.7742 0.8223 0.3175 1.3377 2.6710
homocitrulline NA 0.6828 0.7558 0.2172 0.9967 2.3475
hypotaurine 0.4116 0.2292 2.2107 0.5040 0.3390 2.3055
hypoxanthine 0.0925 1.4462 0.5550 0.6308 1.7108 1.5647
IMP 0.0593 0.4159 1.1255 0.3393 1.0011 3.0588
Indole-3-acrylate 0.1325 0.5043 1.1548 0.3600 0.8742 2.9742
Indole-3-aldehyde 0.1182 0.4142 1.2079 0.2823 0.8237 3.1536
inosine 0.0324 2.8743 0.5206 0.0434 1.2228 1.3065
isoleucine 0.1869 0.5786 1.3336 0.3855 0.7433 2.7721
kynurenine 0.1198 0.4238 0.8367 0.3823 1.0347 3.2027
lactate 0.0932 0.1753 0.4601 0.4031 0.5980 4.2702
leucine 0.1909 0.9497 1.3173 0.3341 0.8325 2.3754
lysine 0.0879 0.4461 1.1441 0.2339 0.8221 3.2658
malate 0.1106 0.5224 1.2715 0.1900 1.4914 2.4142
methionine 0.1875 0.2856 1.6993 0.3077 0.4366 3.0833
methionine sulfone 0.2823 0.2916 1.0876 0.4449 0.7306 3.1631
methionine sulfoxide 0.0424 0.0760 1.3410 0.1142 0.1980 4.2284
methylhistidine 0.1570 0.3394 0.8698 0.2462 0.6790 3.7086
N2-gamma-glutamylglutamine 0.0841 1.4002 1.3918 0.2107 0.9582 1.9549
N3,N4-dimethylarginine 0.0759 0.6467 0.9762 0.2442 0.9937 3.0633
N6-methyllysine 0.0471 0.2921 1.4211 0.1358 0.5893 3.5147
N6,N6,N6-trimethyllysine 0.1005 0.3699 1.4975 0.2393 0.5653 3.2274
N-acetylaspartate 0.1162 0.5934 2.3446 0.1668 0.4941 2.2849
N-acetylglutamine 0.1283 1.1457 1.8854 0.1923 0.9804 1.6679
N-acetylhistidine 0.0695 0.0906 0.5501 0.3056 0.3516 4.6326
N-acetylmethionine 0.2079 0.1633 1.4189 0.4102 0.4940 3.3056
N-acetylneuraminate 0.0999 1.8181 1.1349 0.1007 1.8446 1.0018
N-acetylserine 0.1038 0.3370 1.0638 0.3272 0.6112 3.5570
NAD 0.1041 2.1367 1.2052 0.1184 1.5376 0.8980
NADH 0.0536 NA 0.5541 0.1875 1.4128 2.7920
NADP 0.0560 2.5649 0.5216 0.1004 2.1148 0.6424
NADPH NA 0.4466 0.8614 0.0507 1.8705 1.7708
N-formylmethionine 0.1129 0.2973 0.8814 0.3623 0.8901 3.4559
nicotinamide mononucleotide 0.0197 2.1397 0.8320 0.0319 1.8937 1.0830
nicotinamide riboside 0.1883 0.8669 1.6185 0.2191 1.0799 2.0273
ophthalmate 0.0433 0.4512 1.1904 0.2396 0.9605 3.1150
ornithine 0.0990 0.1991 1.2272 0.3228 0.7684 3.3834
orotate NA 0.4046 1.0052 0.2439 0.6534 2.6929
oxidized glutathione 0.0296 0.7116 0.5145 0.2048 1.1399 3.3996
palmitoyl sphingomyelin 0.1256 0.8166 2.0661 0.1438 0.8330 2.0149
pantothenate 0.1439 0.3026 1.3042 0.4564 0.6987 3.0942
pentitol 0.1739 0.4807 0.9464 0.3550 0.7826 3.2614
pentose phosphate 0.1435 1.0491 1.7965 0.3535 1.2440 1.4134
phenylacetylglycine 0.2488 0.1434 0.6273 0.7161 0.5585 3.7059
phenylalanine 0.2115 0.6440 0.7955 0.5933 1.3913 2.3644
phosphocreatine 0.1653 0.6095 1.7315 0.3279 0.6455 2.5203
phosphoenolpyruvate 0.0327 4.0297 0.3787 0.0311 1.4067 0.1210
phosphoethanolamine 0.0937 1.3501 2.1988 0.1384 0.6080 1.6111
phosphorylcholine 0.0435 2.4031 2.2643 0.0302 0.5186 0.7403
proline 0.1411 0.3125 1.1326 0.5635 0.9203 2.9300
pseudouridine 0.1335 0.2094 0.7366 0.5042 0.7947 3.6217
pyroglutamate 0.0617 1.6477 0.7431 0.2743 0.7174 2.5559
pyruvate 0.0561 2.5073 0.4051 0.0489 2.4565 0.5262
S-(2-succinyl)cysteine NA 0.1359 1.3703 NA 0.2317 2.2621
S-adenosylhomocysteine 0.0788 1.0612 0.9877 0.1913 1.4214 2.2596
S-adenosylmethionine 0.3505 1.0435 1.1335 0.6642 1.3994 1.4090
sedoheptulose 7-phosphate 0.2005 0.4909 2.3728 0.2100 0.4406 2.2853
serine 0.3727 0.6721 1.6424 0.3841 0.8432 2.0855
S-lactoylglutathione 0.0613 2.5204 0.5028 0.1877 1.8205 0.9072
sphinganine 0.0094 2.5484 0.8078 0.0039 2.0078 0.6226
succinate NA 0.7703 1.0743 NA 0.7532 1.4021
targinine 0.0553 0.5262 0.9127 0.2042 0.9498 3.3519
taurine 0.3407 0.5002 1.6019 0.4619 0.6978 2.3974
thiamine 0.0485 0.1552 0.4398 0.2750 0.6496 4.4320
thiamine pyrophosphate 0.0126 2.1583 0.6204 0.0381 2.3833 0.7873
threonine 0.1165 0.2377 1.0538 0.4159 0.7266 3.4494
tryptophan 0.1451 0.5038 1.1663 0.3541 0.8719 2.9588
tyrosine 0.1025 0.3999 1.4067 0.2942 0.7362 3.0606
UDP 0.1509 1.0236 1.3933 0.2458 1.3051 1.8813
UDP-GlcNAc 0.0656 1.4340 1.3744 0.1525 1.2257 1.7477
UDP-glucose 0.1443 1.0200 2.8707 0.0940 0.2171 1.6540
UDP-glucuronate 0.1901 1.4365 1.7031 0.2273 0.6211 1.8219
UMP 0.0749 2.8956 0.9595 0.0808 1.3656 0.6237
uric acid 0.0557 0.1314 1.9921 0.1414 0.1959 3.4835
uridine 0.1189 1.1180 0.8868 0.2720 0.7287 2.8756
urocanate 0.6455 1.8106 1.4923 0.4106 0.7242 0.9168
valine 0.1790 0.3876 1.2815 0.4218 0.6561 3.0740
xanthine 0.2729 1.0276 1.2909 0.5503 0.8736 1.9847
Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1Treatment:hypoxia | Cellular fraction:cytosolic
F2Treatment:hypoxia | Cellular fraction:mitochondrial
F3Treatment:hypoxia | Cellular fraction:whole cell
F4Treatment:normoxia | Cellular fraction:cytosolic
F5Treatment:normoxia | Cellular fraction:mitochondrial
F6Treatment:normoxia | Cellular fraction:whole cell
  logo