Data for (Study ST002248)

(Analysis AN003674)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

MetaboliteF1F2F3F4
11a-Hydroxyprogesterone 1.6147 0.6874 0.6700 0.8979
1,3,5-Trimethoxybenzene 0.9405 0.9728 1.0841 1.0026
17a-Ethynylestradiol 1.0376 0.9515 1.1066 0.9043
17-Hydroxyprogesterone 1.1344 1.1056 0.9233 0.8499
1-Butanol 1.1058 0.6568 0.7045 1.5329
1-Methylhistidine 1.1032 1.0738 0.8826 0.9404
1-Methylnicotinamide NA NA 1.1356 0.5931
2,3-Diaminopropionic acid 1.1484 0.7261 0.9390 1.1864
2,5-Furandicarboxylic acid 0.9915 0.8910 1.0103 1.1072
2-Hydroxy-3-methylbutyric acid 1.0281 1.0603 0.9020 1.0096
2-Hydroxyadenine 0.9980 1.0630 1.0726 0.8662
2-Hydroxybutyric acid 0.9913 1.0607 0.8256 1.1213
2-Hydroxycaproic acid 0.2427 0.4243 0.6364 2.4139
2-Isopropylmalic acid 0.9350 1.0443 1.0593 0.9614
2-Phenylglycine 1.4464 0.6857 0.9225 0.9060
2-Pyrrolidinone 0.9121 0.8611 0.9233 1.3035
3,4,5-Trimethoxycinnamic acid 0.9949 0.9394 0.7066 1.3591
3,4-Dihydroxyphenylglycol 0.6844 2.0339 0.7135 0.4966
3-Methoxyphenylacetic acid 1.0339 0.9942 0.9632 1.0086
3-Methylindole 1.1318 0.8111 0.8918 1.1518
3-Phenoxypropionic acid 0.7290 0.8915 1.3597 1.0198
4-Aminohippuric acid 0.8585 0.8653 1.2860 0.9901
5-Dodecenoic acid 0.8246 0.9208 1.0203 1.2343
5-Methoxytryptophol 0.8816 0.8598 1.2276 1.0309
5-Phenylvaleric acid 0.9348 1.0745 0.9138 1.0863
5-Thymidylic acid 0.4058 0.3458 0.3400 2.9084
6-Dimethylaminopurine 0.7777 0.9158 0.8893 1.4172
7-Ketocholesterol 1.2775 0.5545 0.4197 1.5991
7-Methylguanosine 0.8475 0.8598 1.4412 1.0546
Acetaminophen 1.0371 1.0486 0.9419 0.9632
Acetic acid 0.9186 1.0140 0.9796 1.0878
Acetylcysteine 1.1518 0.5715 1.1932 1.0835
Adenine 1.1482 1.2215 0.6954 0.9349
Adenosine monophosphate 1.3162 0.8924 1.0683 0.6836
Alloxan 1.0861 0.8234 1.0029 1.0876
Alpha-Aspartyl-lysine 0.9838 0.9658 0.9567 1.1070
Alpha-ketoisovaleric acid 1.1539 0.8103 0.9027 1.1330
Alpha-N-phenylacetyl-L-glutamine 0.8863 0.7911 1.3160 1.0067
Anserine 0.7067 1.1757 1.0500 1.1020
Aspartame 0.8985 0.5481 1.8676 0.6293
Asymmetric dimethylarginine 1.4487 0.6396 0.6127 1.3292
Azythromycin 0.7603 1.8312 1.0811 0.3578
Benzaldehyde 1.2753 0.6397 1.1165 0.9685
Benzoic acid 1.2046 0.5601 1.2547 0.9805
Biotin 1.0256 1.0274 0.9463 1.0008
Caffeine 0.9040 1.0674 0.9958 1.0412
Cinnamic acid 1.2582 0.5464 1.1077 1.0309
Cis-Aconitic acid 0.8475 1.0674 0.9930 1.1053
Citramalic acid 1.0373 0.9593 1.0084 0.9950
Cortisol 1.0670 1.0102 1.0503 0.8822
Creatine 0.9246 0.6254 0.9576 1.4924
Cyclic AMP 0.9724 1.2586 0.7018 1.0996
Dehydroascorbic acid 0.8953 1.1148 0.9688 1.0212
Deoxyadenosine 0.9390 1.1206 0.6722 1.1938
Deoxycholic acid glycine conjugate 1.0492 0.9916 0.9207 1.0385
Deoxycorticosterone 1.5654 0.8358 0.7210 0.8778
Deoxyguanosine 1.2244 1.0258 0.9794 0.7704
Dextromethorphan 1.2646 0.7966 0.8617 1.0517
D-Glucurono-6,3-lactone 0.8555 1.0076 1.1059 1.0805
Diaminopimelic acid 1.0157 0.9609 1.0510 0.9723
Diphenhydramine 1.1799 0.8324 0.9841 1.0275
DL-a-glycerophosphate 1.0059 0.9676 0.9764 1.0501
Doxylamine 1.0091 1.0867 0.9369 0.9594
Elaidic acid 0.9306 0.9669 0.8247 1.2778
Erythrose 0.9375 1.0592 0.9948 1.0085
Estrone 0.9522 1.0620 1.0017 0.9842
Gluconolactone 1.1711 0.9560 1.0536 0.8193
Glucosamine 1.0406 0.9954 1.0008 0.9632
Glutathione 1.1529 0.9818 1.0369 0.8284
Glycerophosphocholine 0.9792 1.0356 1.0266 0.9586
Glycine 1.3386 0.4087 1.2614 0.9914
Glycyl-L-leucine 0.9539 1.0932 1.0078 0.9519
Guanine 0.9673 0.9277 1.1687 0.9363
Guanosine 1.1990 1.0431 0.9202 0.8377
Heptadecanoic acid 0.9834 1.0524 1.0372 0.9252
Homoveratric acid 0.9630 1.1299 0.9936 0.9135
Hypoxanthine 1.1087 0.8080 0.9358 1.1475
Ibuprofen 0.8631 1.1092 0.8982 1.1294
Indole 1.3509 0.5362 1.1387 0.9742
Indole-3-carbinol 1.2132 0.6624 1.0895 0.9901
Indole-3-carboxylic acid 1.3016 0.5318 1.1035 1.0631
Indoleacetic acid 1.8808 0.2326 1.3616 0.5250
Indoleacrylic acid 1.2737 0.5533 1.1762 0.9968
Inosine 0.9105 0.8443 1.1907 1.0545
Isobutyric acid 1.0264 0.8843 1.0438 1.0455
Isoguanine 0.9588 1.0075 0.9857 1.0480
Isovalerylcarnitine 1.1772 0.8217 1.0877 0.9134
L-Acetylcarnitine 1.3305 0.8666 0.9460 0.8568
L-Arginine 1.0308 0.4809 1.2341 1.2542
L-Dopa 0.9222 1.2704 0.9932 0.8141
L-Glutamic acid 2.3183 0.5435 0.8104 1.9379
L-Glutamine 0.9445 1.0551 0.8388 1.1616
Linoleic acid 1.0427 0.9638 1.0272 0.9662
L-Malic acid 0.8253 1.0737 1.0850 1.0266
L-Methionine 1.1974 0.7001 1.0447 1.0204
L(-)-Nicotine pestanal 0.9485 1.0593 0.9895 1.0027
L-Norleucine 1.1837 0.5385 1.2497 1.0281
L-Phenylalanine 1.2419 0.5987 1.1242 1.0352
L-Proline 0.5049 0.4334 2.4729 0.5269
L-Tryptophan 1.2164 0.5695 1.1944 1.0197
L-Tyrosine 1.1849 0.5582 1.2664 0.9905
L-Valine 0.9632 0.5459 1.5025 0.9883
m-Coumaric acid 1.2230 0.5492 1.2617 0.9661
Medroxyprogesterone 0.9990 1.1217 0.9746 0.9047
Melatonin 0.9799 1.0370 1.0015 0.9816
Methylhippuric acid 1.1834 0.4751 1.2769 0.9990
Metoprolol 1.0357 1.0209 0.9984 0.9449
N1-Acetylspermine 1.0446 0.9878 1.0181 0.9487
N-Acetylputrescine 0.8669 0.8907 0.9192 1.3233
NADH 0.8550 0.9892 1.0070 1.1506
Niacinamide 1.2245 0.7678 1.0376 0.9702
N,N-Dimethylformamide 1.0735 0.5124 1.0313 1.3218
Norepinephrine 1.2207 0.4551 0.8883 1.4360
Normetanephrine 1.2866 0.7570 1.0398 0.9166
Nutriacholic acid 1.3345 0.4493 0.6909 1.5253
Octadecanedioic acid 1.1590 0.8557 1.0041 0.9580
o-Tyrosine 1.0131 0.9703 1.0916 0.9251
Oxypurinol 1.0975 0.8706 1.4064 0.6255
Pantothenic acid 1.3718 0.5708 1.1497 0.9076
PC(16:0/16:0) 4.2349 0.5965 1.1068 0.2679
PC(18:1(9Z)/18:1(9Z)) 0.1650 1.7117 1.3054 0.5601
Perillic acid 0.9878 0.7378 1.2431 1.0314
Phenylacetaldehyde 1.1388 0.8601 0.8896 1.1115
Phenylacetic acid 1.2790 1.0479 0.8991 0.7740
Phenylpropanolamine 0.8038 0.9683 1.2870 0.9409
Phosphoric acid 1.0110 0.9801 0.9660 1.0429
Propanal 0.8519 0.9578 0.9322 1.2581
Protocatechuic acid 0.8061 0.5201 0.7030 2.0680
Pyridine 0.9708 0.8767 0.9952 1.1573
Pyridoxal 0.8416 0.7938 1.4146 0.9302
Pyridoxal 5^-phosphate 0.8469 1.0176 0.9714 1.1630
Pyrimidine 1.0692 0.7504 1.3504 0.8300
Pyroglutamic acid 1.1291 0.4295 1.2560 1.1854
Quercetin 1.5598 0.2812 0.9628 0.9267
Rhamnose 0.6800 1.4204 0.8791 1.0205
Rutin 1.0597 0.7616 0.9392 1.2396
Sorbitol 0.9604 0.9928 1.0744 0.9724
Spermine 1.8179 1.0560 0.7023 0.3416
Sphinganine 0.8310 1.0504 1.0310 1.0876
Sphingosine 0.9800 0.9628 0.8521 1.2051
Succinic acid 1.1183 1.2607 0.7615 0.8595
Succinylacetone 1.0841 0.7759 0.8865 1.2535
Syringic acid 0.9713 1.0389 1.0070 0.9732
Taurodeoxycholic acid NA 0.8914 1.2698 0.9737
Terephthalic acid 1.1566 0.4323 0.7511 1.5891
Tetrahydrocortisone 1.0256 1.0787 1.0464 0.8493
Threonic acid 1.1973 0.9850 1.2914 0.5263
Thymidine 0.8008 0.5887 1.6524 0.9582
Trans-Cinnamic acid 0.9949 1.0334 0.9779 0.9938
Traumatic acid 1.0300 0.8690 1.1058 0.9951
Tricosanoic acid 1.3945 NA 0.9957 0.4125
Triethylamine 0.8818 0.8951 1.0468 1.1763
Trimethylamine 0.8348 0.6416 1.6645 0.8591
Tryptamine 0.9748 0.8874 1.0759 1.0619
Ureidosuccinic acid 0.9437 0.9988 1.0893 0.9681
Uridine 0.9519 1.0435 1.0867 0.9179
Uridine 5^-monophosphate 1.9406 0.2365 0.8885 0.8390
Uridine diphosphate-N-acetylglucosamine 0.8891 0.7980 0.9948 1.2922
Urocanic acid 0.9874 1.0287 1.0168 0.9670
Verapamil 1.3627 0.7823 0.8349 1.0200
Vitamin D3 0.9148 0.7944 0.9247 1.3662
Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1Treatment:Control
F2Treatment:Drug Free PLGA Nanoparticle
F3Treatment:Free PTX
F4Treatment:PTX-PLGA Nanoparticle
  logo