Data for (Study ST002264)
(Analysis AN003699)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3-(2-Hydroxyphenyl)propanoic acid | 0.6960 | 1.1630 | 1.1847 | 1.5564 | 1.0041 | 0.7452 | 0.8547 | 0.9285 | 1.8409 | 0.7337 | 1.1359 | 0.9252 | 0.8214 | 0.8900 | 1.2737 | 0.9107 | 0.7510 |
| 3-Phosphoglyceric acid | 1.6523 | 1.5327 | 0.8642 | 1.5807 | 0.9227 | 0.4108 | 0.6984 | 0.8848 | 0.7232 | 1.8365 | 0.2253 | 1.8198 | 1.4425 | 1.0810 | 0.7861 | 2.1384 | 0.0252 |
| 3-Sulfinoalanine | 1.6966 | 1.7648 | 0.8263 | 2.1868 | 1.3658 | 0.8695 | 1.0411 | 0.9769 | 0.3021 | 1.1888 | 0.1244 | 1.5175 | 0.8999 | 1.1095 | 0.3682 | 2.4159 | 0.0047 |
| 5-Hydroxyindoleacetic acid | 1.1143 | 1.4700 | 0.9725 | 0.9786 | 0.7624 | 1.1259 | 0.9958 | 0.5807 | 1.0876 | 0.7991 | 0.8944 | 1.3043 | 0.6521 | 1.0483 | 0.5922 | 0.5235 | 1.4119 |
| 5-Hydroxymethyluracil | 0.8500 | 1.1356 | 0.7561 | 0.9213 | 0.9586 | 0.9630 | 0.9061 | 2.0508 | 0.6766 | 0.7276 | 0.8937 | 0.7201 | 0.7631 | 1.0399 | 1.0190 | 0.7837 | 1.3130 |
| Acetylcysteine | 0.7178 | 1.9372 | 0.7997 | 1.5517 | 1.7135 | 0.5132 | 1.1913 | 0.5044 | 1.0662 | 1.4964 | 1.3332 | 0.5886 | 0.4615 | 1.8099 | 0.6910 | 0.5068 | 0.6691 |
| Adenine | 1.4470 | 1.1828 | 1.4410 | 1.4744 | 1.3496 | 1.2106 | 1.4450 | 1.2217 | 0.9019 | 0.7833 | 0.5058 | 1.1386 | 1.1546 | 0.6738 | 0.9698 | 1.1030 | 0.2489 |
| ADP-glucose | 1.5173 | 1.4190 | 1.2329 | 1.4912 | 1.3255 | 0.9187 | 1.1829 | 0.9010 | 0.7335 | 1.1545 | 0.5492 | 1.0510 | 1.0041 | 1.0258 | 0.9319 | 1.1555 | 0.0436 |
| All-trans-retinoic acid | 1.2491 | 1.0443 | 1.1029 | 1.6657 | 1.0716 | 1.0229 | 1.7221 | 0.9788 | 1.4140 | 0.5942 | 0.5824 | 0.6426 | 0.8360 | 1.1930 | 0.8535 | 0.8994 | 0.6728 |
| Aminoadipic acid | 1.1469 | 0.8441 | 0.9793 | 0.9961 | 1.2657 | 0.8503 | 1.2349 | 0.7786 | 0.8572 | 1.4608 | 1.2849 | 1.3330 | 1.4923 | 1.1191 | 1.0846 | 1.4011 | 0.2017 |
| Arachidic acid | 1.0661 | 1.1741 | 1.2272 | 1.3131 | 1.2253 | 1.0970 | 1.1438 | 1.1623 | 0.9819 | 0.8369 | 0.9620 | 0.6704 | 1.2171 | 0.9405 | 0.9473 | 0.7073 | 0.7479 |
| Aspartic acid | 1.4129 | 1.2512 | 0.9529 | 1.4066 | 1.3398 | 1.1513 | 1.0116 | 1.0834 | 0.7991 | 1.3254 | 0.4746 | 1.7543 | 0.8644 | 1.4449 | 0.7555 | 1.6258 | 0.0049 |
| Caffeic acid | 0.8061 | 0.6045 | 1.0819 | 0.9498 | 0.7948 | 0.9599 | 1.0345 | 1.3438 | 2.7492 | 0.8055 | 2.2462 | 0.6551 | 0.7880 | 0.5233 | 0.8336 | 0.5769 | 0.7176 |
| CDP | 1.5790 | 0.8825 | 1.6251 | 1.2413 | 1.1117 | 0.4804 | 0.8506 | 0.5984 | 1.1945 | 0.7805 | 1.0701 | 1.0101 | 1.0734 | 0.6193 | 1.0851 | 1.1030 | 0.0847 |
| Citramalic acid | 1.2313 | 1.4839 | 1.0602 | 1.2926 | 1.3626 | 1.1988 | 1.2544 | 1.0434 | 0.7943 | 1.3347 | 0.5156 | 1.3791 | 1.0399 | 1.1689 | 0.8793 | 1.5265 | 0.0380 |
| Citrulline | 1.5111 | 1.0670 | 1.7838 | 1.3416 | 1.2553 | 0.8091 | 1.1017 | 0.8995 | 1.3036 | 0.9264 | 0.6680 | 1.0117 | 1.2203 | 0.8194 | 1.5225 | 0.9494 | 0.1786 |
| Cortisol | 0.0447 | 0.6099 | 0.5544 | 0.9144 | 0.1353 | 1.6224 | 0.4199 | 1.7561 | 0.4293 | 0.0786 | 0.5236 | 0.1728 | NA | 0.0067 | NA | NA | 2.0221 |
| Creatinine | 0.7767 | 0.7486 | 0.8042 | 0.3471 | 0.5907 | 1.0510 | 0.9610 | 1.3763 | 0.7711 | 0.8494 | 0.6575 | 0.5928 | 1.0946 | 1.0153 | 1.5848 | 0.7934 | 1.7447 |
| Cyclic AMP | 1.5325 | 1.2540 | 1.0081 | 1.8487 | 0.8842 | 0.8290 | 0.6886 | 0.8465 | 0.4617 | 1.1473 | NA | 1.2846 | 0.6677 | 1.0018 | 0.5447 | 0.6695 | NA |
| Cystine | 0.8059 | 0.4388 | 1.2597 | 0.3464 | 0.8691 | 0.4422 | 0.7425 | 0.3111 | 1.9356 | 0.2505 | 3.9549 | 0.2148 | 1.9597 | 0.3061 | 1.8900 | 0.3120 | 0.8871 |
| Cytidine monophosphate | 1.3094 | 1.0165 | 1.1563 | 1.6558 | 0.8908 | 0.5198 | 0.9496 | 0.7330 | 0.7062 | 1.3152 | 0.7172 | 2.0236 | 0.5632 | 0.9313 | 0.6748 | 1.1565 | 0.0423 |
| Cytidine triphosphate | 2.1572 | 0.5759 | 2.3336 | 0.7687 | 1.1383 | 0.2089 | 0.5446 | 0.5727 | 2.1516 | 0.1400 | 0.7314 | 0.4206 | 1.6808 | 0.3663 | 1.4047 | 0.8046 | NA |
| Diaminopimelic acid | 1.2910 | 1.2462 | 0.8841 | 1.4366 | 1.7054 | 1.4374 | 1.3459 | 0.5684 | 1.0598 | 1.0534 | 0.4697 | 1.2456 | 0.6041 | 1.1904 | 0.9476 | 1.0382 | 0.4286 |
| Docosahexaenoic acid | 0.9074 | 1.4627 | 1.0717 | 1.0201 | 1.1404 | 2.0332 | 1.1440 | 0.9503 | 1.1108 | 0.7977 | 0.9027 | 0.8340 | 1.1637 | 0.9670 | 1.0804 | 0.7763 | 0.4891 |
| Gamma-Linolenic acid | 0.7747 | 1.0154 | 0.9104 | 0.6848 | 1.2580 | 1.2292 | 1.2029 | 0.6196 | 0.8944 | 0.6066 | 0.6445 | 0.5488 | 1.1575 | 1.0341 | 1.3777 | 0.8237 | 1.4566 |
| Gluconic acid | 0.8160 | 0.8757 | 0.8270 | 0.8316 | 0.7814 | 0.6336 | 0.6713 | 0.4507 | 1.5154 | 1.7108 | 1.3251 | 1.5213 | 1.5576 | 1.5818 | 1.4026 | 1.8321 | 0.1249 |
| Glutamine | 1.4749 | 1.3330 | 1.6724 | 1.2630 | 0.8144 | 0.6543 | 0.7967 | 0.5813 | 1.5329 | 1.1205 | 0.8510 | 1.0273 | 1.5095 | 0.9445 | 1.9229 | 0.9453 | 0.0835 |
| Glycocholic acid | NA | NA | NA | NA | NA | NA | 1.6143 | NA | 0.5535 | NA | NA | NA | NA | NA | NA | 0.8081 | 1.0048 |
| Guanine | 1.7762 | 1.2098 | 1.9067 | 1.1890 | 1.3683 | 0.7567 | 1.3035 | 0.8007 | 1.1823 | 0.6748 | 0.7101 | 0.7021 | 1.3144 | 0.8894 | 1.4895 | 1.0406 | 0.1321 |
| Guanosine monophosphate | 0.6090 | 1.2722 | 0.5038 | 1.6756 | 0.7026 | 0.9840 | 0.8649 | 1.0206 | 0.5696 | 2.2097 | 0.5419 | 2.0921 | 0.5507 | 1.8805 | 0.5657 | 1.6179 | 0.0035 |
| Histidine | 1.4703 | 1.3015 | 1.4838 | 1.1781 | 1.2862 | 0.7854 | 1.3036 | 0.6944 | 1.4121 | 0.7788 | 1.0944 | 0.8595 | 1.0467 | 0.7692 | 1.3286 | 0.8106 | 0.3988 |
| Hydroxypyruvic acid | 0.9819 | 1.4478 | 1.4386 | 0.7089 | 1.0939 | 1.0946 | 1.0067 | 1.1289 | 0.8361 | 1.8562 | 0.3867 | 1.6448 | 0.6693 | 2.3053 | 0.5644 | 1.0434 | 0.1722 |
| Hypoxanthine | 1.6730 | 1.5182 | 1.3535 | 1.3569 | 1.9880 | 1.2229 | 1.4338 | 1.4947 | 0.6421 | 0.9217 | 0.2924 | 0.9442 | 0.8838 | 0.8526 | 0.6764 | 1.0798 | 0.1247 |
| Imidazoleacetic acid | 0.6769 | 0.7381 | 0.8527 | 0.6929 | 0.8176 | 1.7411 | 1.2872 | 1.6604 | 0.6197 | 0.6208 | 0.7490 | 0.5981 | 1.0768 | 1.1238 | 1.5509 | 0.7917 | 1.1508 |
| Inosinic acid | 1.2178 | 1.0351 | 1.1450 | 1.3602 | 1.0465 | 0.6183 | 0.9945 | 0.9398 | 0.5586 | 1.5920 | 0.6180 | 2.8201 | 0.7676 | 1.4858 | 0.6295 | 1.4927 | 0.0050 |
| Kynurenic acid | 0.0624 | 0.3728 | 0.2911 | 0.5303 | 0.3965 | 1.2978 | 1.2909 | 0.3551 | 0.5393 | 0.1486 | 0.2471 | 0.2152 | 0.1386 | 0.1408 | 0.3623 | 0.1785 | 4.5373 |
| Linoleic acid | 0.8131 | 1.0081 | 0.8425 | 0.6873 | 1.0531 | 1.0597 | 1.1438 | 0.6881 | 1.0049 | 0.6585 | 0.7324 | 0.5965 | 1.1809 | 1.0519 | 1.2504 | 0.8794 | 1.5060 |
| Lysine | 1.8177 | 1.9863 | 2.5092 | 1.7215 | 1.6208 | 0.8502 | 1.1949 | 0.6739 | 0.4451 | 0.3245 | 0.7801 | 0.2580 | 1.5684 | 0.3328 | 0.9748 | 0.3605 | 0.4680 |
| Methionine | 1.3116 | 1.7797 | 1.1186 | 1.4674 | 1.1498 | 1.1773 | 1.0913 | 1.1062 | 1.0010 | 1.1216 | 0.5590 | 0.9318 | 0.9591 | 0.9654 | 0.9719 | 0.9153 | 0.3899 |
| Mevalonic acid | NA | 0.7991 | 0.5673 | 0.7774 | NA | NA | NA | NA | NA | 1.6461 | 1.2685 | 0.1643 | 0.9286 | NA | 1.4600 | NA | NA |
| Myristic acid | 0.6291 | 1.0967 | 0.8262 | 0.7869 | 1.2522 | 1.0894 | 1.1610 | 0.6920 | 0.8209 | 0.5097 | 0.6122 | 0.4883 | 1.0682 | 0.9898 | 1.3766 | 1.0309 | 1.5887 |
| N-Acetylasparagine | 1.8390 | 1.0927 | 1.0562 | 0.8643 | 0.9497 | 0.7993 | 1.0675 | 1.2553 | 0.8608 | 0.8752 | 1.0046 | 1.0402 | 1.5295 | 0.8927 | 0.8000 | 1.3816 | 0.5093 |
| N-Acetyl-L-aspartic acid | 1.0791 | 1.9940 | 0.7996 | 2.2345 | 1.3142 | 1.3222 | 1.1535 | 1.4017 | 0.8552 | 0.9793 | 1.1775 | 1.0967 | 0.4479 | 0.9470 | 0.7164 | 1.0202 | 0.0479 |
| N-Acetyl-L-methionine | 1.5111 | 2.6079 | 0.9426 | 1.1801 | 0.7983 | 0.7050 | 0.6923 | 0.5900 | 1.2754 | 1.6387 | 0.8402 | 1.1931 | 1.1096 | 1.2725 | 0.7877 | 1.1203 | 0.1508 |
| N-Acetylneuraminic acid | 0.9391 | 1.8757 | 0.8573 | 1.6837 | 0.8377 | 1.0932 | 0.9937 | 0.9669 | 0.6606 | 1.9008 | 0.4457 | 1.7850 | 0.6825 | 1.4590 | 0.6675 | 1.5225 | 0.1110 |
| N-Alpha-acetyllysine | 0.8277 | 1.8833 | 0.5701 | 1.2753 | 0.8356 | 1.3739 | 0.9049 | 0.4000 | 1.5066 | 2.1477 | 0.6423 | 0.7554 | 0.6841 | 2.2648 | 0.6597 | 0.6242 | 0.4917 |
| N-Formyl-L-methionine | 1.5052 | NA | 0.6021 | NA | 0.5280 | 0.2057 | 1.2845 | 1.4243 | 0.9609 | NA | 1.3008 | NA | 0.6139 | 1.9535 | 1.0927 | 2.9295 | 0.2875 |
| Orotic acid | 1.1954 | 1.0749 | 0.9081 | 0.9516 | 1.3908 | 1.1069 | 1.0460 | 1.0864 | 1.0796 | 1.0673 | 0.6407 | 1.2489 | 1.1270 | 1.0184 | 0.7854 | 1.0286 | 0.7164 |
| Palmitoleic acid | 0.8442 | 1.3632 | 1.0361 | 0.9392 | 1.2443 | 1.0416 | 1.2542 | 0.6899 | 0.8221 | 0.6297 | 0.6852 | 0.4640 | 1.0648 | 0.8587 | 1.3015 | 0.7113 | 1.3938 |
| Pantothenic acid | 2.4922 | 1.0335 | 1.8042 | 1.0607 | 0.9483 | 0.4737 | 0.7114 | 0.4874 | 1.2646 | 1.1724 | 1.3139 | 1.2798 | 1.5924 | 0.7040 | 1.4294 | 0.8261 | 0.0272 |
| Phenylalanine | 1.2945 | 1.4796 | 1.4108 | 1.1347 | 1.0208 | 0.8554 | 1.1108 | 0.5860 | 1.2841 | 0.6144 | 1.1210 | 0.4842 | 0.9200 | 0.6606 | 1.1922 | 0.5344 | 1.1112 |
| Phosphocreatine | 0.9065 | 2.5975 | 2.0766 | NA | 0.2254 | NA | 0.1381 | 1.6529 | 0.8707 | NA | 0.8374 | NA | 0.6465 | NA | 0.4277 | NA | NA |
| Proline | 1.1637 | 1.2718 | 0.7380 | 1.2695 | 0.7693 | 1.2693 | 0.7996 | 0.8635 | 0.9138 | 1.0749 | 1.1120 | 1.3899 | 1.2002 | 0.4920 | 0.8233 | 0.5088 | 1.1277 |
| Pyrrole-2-carboxylic acid | 0.4696 | 0.5989 | 0.9881 | 0.4522 | 0.7310 | 1.5401 | 1.0811 | 1.5388 | 0.7219 | 0.8243 | 0.8463 | 0.9454 | 1.0069 | 1.2863 | 1.1898 | 1.0551 | 1.2715 |
| Pyruvic acid | 1.5556 | 1.3593 | 1.5510 | 1.4181 | 1.3269 | 0.8020 | 1.1867 | 0.7989 | 1.1501 | 1.0273 | 0.8876 | 1.2699 | 1.0053 | 0.8258 | 1.0954 | 1.0782 | 0.1231 |
| Ribose 5-phosphate | 1.5732 | 1.8123 | 1.3045 | 1.5220 | 1.2149 | 0.8684 | 1.1521 | 0.7592 | 0.8585 | 1.1742 | 0.4202 | 1.2790 | 1.1801 | 1.0020 | 1.1759 | 1.3535 | 0.0062 |
| S-Adenosylhomocysteine | 1.3728 | 1.4457 | 0.9805 | 1.6824 | 1.2796 | 1.2970 | 0.7180 | 0.9159 | 0.4951 | 0.8771 | 0.2990 | 1.0224 | 0.5549 | 1.3506 | 0.5146 | 1.1944 | NA |
| Serine | 1.5222 | 2.0276 | 1.2636 | 1.4654 | 1.2541 | 0.8399 | 1.1382 | 0.8059 | 1.1310 | 1.2423 | 0.4593 | 1.0120 | 1.1749 | 0.8232 | 1.1909 | 0.9146 | 0.1506 |
| trans-Aconitic acid | 1.4439 | 1.6651 | 1.1932 | 1.9109 | 1.1073 | 0.8464 | 1.1838 | 0.7943 | 1.0328 | 1.1547 | 1.0497 | 1.1525 | 0.8691 | 1.0096 | 1.0185 | 1.1156 | 0.0447 |
| trans-Cinnamic acid | 1.0909 | 1.4045 | 1.4440 | 0.9920 | 0.7598 | 1.0600 | 0.9275 | 0.7982 | 1.7358 | 0.9330 | 1.2254 | 0.3382 | 0.9553 | 0.4636 | 1.0659 | 0.3708 | 1.1631 |
| Tyrosine | 1.1451 | 1.4474 | 1.0266 | 1.1087 | 1.1153 | 0.8869 | 1.0694 | 0.7852 | 1.1163 | 0.8476 | 0.8255 | 0.7861 | 0.7507 | 0.7179 | 0.8531 | 0.7640 | 1.2829 |
| Uracil | 1.4322 | 1.3514 | 0.8229 | 1.1717 | 1.6954 | 1.0878 | 1.5365 | 0.7838 | 0.6804 | 1.0322 | 0.5481 | 0.6945 | 1.0632 | 1.2814 | 0.8514 | 1.3590 | 0.4779 |
| Uric acid | 0.4861 | 1.4523 | 0.7995 | 1.5525 | 0.5882 | 1.1582 | 0.4895 | 0.8134 | 0.8257 | 1.1607 | 0.8491 | 0.5554 | 0.3307 | 1.1844 | 0.4082 | 1.3617 | 1.7442 |
| Uridine | 2.3569 | 1.3095 | 1.9296 | 1.3474 | 1.1956 | 0.4792 | 0.9634 | 0.4634 | 1.3532 | 0.6992 | 0.8759 | 1.2213 | 1.1275 | 0.7263 | 1.3130 | 0.8065 | 0.1870 |
| Uridine 5-monophosphate | 0.8595 | 1.0569 | 0.9045 | 1.7882 | 0.7361 | 0.6890 | 0.7371 | 0.8078 | 1.1105 | 1.8166 | 1.1283 | 2.6065 | 0.6943 | 1.1830 | 0.8255 | 1.0461 | 0.0050 |
| Uridine triphosphate | 1.7973 | 0.7228 | 2.1591 | 0.7925 | 1.3778 | 0.3215 | 0.7053 | 0.7400 | 1.4539 | 0.3492 | 0.7291 | 0.6279 | 1.4237 | 0.4659 | 1.3576 | 0.9763 | NA |
| Xanthine | 1.1993 | 2.2619 | 0.7290 | 1.7839 | 1.3855 | 0.9856 | 1.0179 | 0.9063 | 0.5469 | 1.3385 | 0.3294 | 1.5518 | 0.5533 | 1.5814 | 0.5354 | 1.6644 | 0.1110 |
Factors:
| F1 | sample type:Mouse Lung Study Sample | Animal:C3H/Hen | Sex:Female | Treatment1:ATG | Treatment2:95hr 100% O2 |
| F2 | sample type:Mouse Lung Study Sample | Animal:C3H/Hen | Sex:Female | Treatment1:ATG | Treatment2:Room Air |
| F3 | sample type:Mouse Lung Study Sample | Animal:C3H/Hen | Sex:Female | Treatment1:Saline | Treatment2:95hr 100% O2 |
| F4 | sample type:Mouse Lung Study Sample | Animal:C3H/Hen | Sex:Female | Treatment1:Saline | Treatment2:Room Air |
| F5 | sample type:Mouse Lung Study Sample | Animal:C3H/Hen | Sex:Male | Treatment1:ATG | Treatment2:95hr 100% O2 |
| F6 | sample type:Mouse Lung Study Sample | Animal:C3H/Hen | Sex:Male | Treatment1:ATG | Treatment2:Room Air |
| F7 | sample type:Mouse Lung Study Sample | Animal:C3H/Hen | Sex:Male | Treatment1:Saline | Treatment2:95hr 100% O2 |
| F8 | sample type:Mouse Lung Study Sample | Animal:C3H/Hen | Sex:Male | Treatment1:Saline | Treatment2:Room Air |
| F9 | sample type:Mouse Lung Study Sample | Animal:C57Bl6 | Sex:Female | Treatment1:ATG | Treatment2:95hr 100% O2 |
| F10 | sample type:Mouse Lung Study Sample | Animal:C57Bl6 | Sex:Female | Treatment1:ATG | Treatment2:Room Air |
| F11 | sample type:Mouse Lung Study Sample | Animal:C57Bl6 | Sex:Female | Treatment1:Saline | Treatment2:95hr 100% O2 |
| F12 | sample type:Mouse Lung Study Sample | Animal:C57Bl6 | Sex:Female | Treatment1:Saline | Treatment2:Room Air |
| F13 | sample type:Mouse Lung Study Sample | Animal:C57Bl6 | Sex:Male | Treatment1:ATG | Treatment2:95hr 100% O2 |
| F14 | sample type:Mouse Lung Study Sample | Animal:C57Bl6 | Sex:Male | Treatment1:ATG | Treatment2:Room Air |
| F15 | sample type:Mouse Lung Study Sample | Animal:C57Bl6 | Sex:Male | Treatment1:Saline | Treatment2:95hr 100% O2 |
| F16 | sample type:Mouse Lung Study Sample | Animal:C57Bl6 | Sex:Male | Treatment1:Saline | Treatment2:Room Air |
| F17 | sample type:plasma | Animal:- | Sex:- | Treatment1:- | Treatment2:- |
