Data for (Study ST002316)

(Analysis AN003783)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4
10-HYDROXYDECANOATE NA NA 0.8841 1.1391
10-Hydroxydecanoic acid NA NA 0.9328 1.0672
10-Undecenoic acid 1.0355 0.9574 NA NA
1-METHYLADENOSINE 0.6647 1.4024 NA NA
1-METHYL-L-HISTIDINE 1.8585 2.0904 0.1207 0.1121
2,3-DIHYDROXYBENZOATE 1.0217 0.9739 NA NA
2,5-DIHYDROXYBENZOATE 1.0202 0.9758 NA NA
2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOSYLAMINE 0.8104 1.2276 NA NA
2-Ethyl-2-hydroxybutyric acid 2.0856 1.9410 0.0684 0.0619
2-HYDROXY-4-(METHYLTHIO)BUTANOATE 0.8980 1.1225 NA NA
2-HYDROXYBUTYRATE 1.3169 2.2495 0.3435 0.2984
2-HYDROXYGLUTARIC 2.7578 1.2203 0.0337 0.0249
2-Hydroxyhexadecanoic acid 1.9232 1.8695 0.1712 0.1810
2-Hydroxyhexanoic acid 1.0343 0.9588 NA NA
2-Hydroxytetradecanoic acid 1.8882 1.8977 0.1012 0.1150
3,3-Dimethylglutaric acid NA NA 0.9527 1.0473
3,4-Dihydroxyhydrocinnamic acid 0.8986 1.1216 NA NA
3,4-DIHYDROXYPHENYLACETATE-2 1.3417 0.5900 NA NA
(3ALPHA,5BETA,7ALPHA)-3,7-DIHYDROXY-12-OXOCHOLAN-24-OIC ACID 3.7695 0.0731 0.0015 0.0014
3-HYDROXYBENZALDEHYDE NA NA 1.0867 0.9133
3-HYDROXYBENZYL ALCOHOL 0.9564 1.0523 NA NA
3-HYDROXYMETHYLGLUTARATE 1.3930 1.4719 0.8483 0.3654
3-Hydroxyoctanoic acid 2.1108 1.5403 0.2092 0.2298
3-Hydroxysebacic acid 1.0586 0.7831 1.2828 0.8393
3-METHYL-2-OXINDOLE 0.8187 1.2175 NA NA
3-METHYLADENINE-3 1.1369 0.8358 NA NA
3-Methylglutarylcarnitine 1.1746 0.8254 NA NA
3-METHYLHISTAMINE 1.0855 0.8975 NA NA
3-PHOSPHOGLYCERATE 1.1701 0.7958 NA NA
[(3R)-3-Hydroxydodecanoyl]-L-carnitine 1.3856 0.5372 NA NA
[(3R)-3-Hydroxyhexadecanoyl]-L-carnitine 1.5346 0.3585 NA NA
3-SULFINOALANINE 0.9514 1.0584 NA NA
4-ACETYLBUTYRATE 1.9546 2.0558 0.0988 0.0667
4-GUANIDINOBUTANOATE 1.3461 0.5847 NA NA
4-HYDROXYBENZALDEHYDE 1.9601 1.8915 0.1387 0.1583
4-HYDROXYBENZOATE 1.9457 1.9855 0.1311 0.1020
4-Hydroxyphenyl-2-propionic acid 0.8986 1.1217 NA NA
4-HYDROXYPHENYLPYRUVATE 1.9857 1.8880 0.1191 0.1552
4-METHYLCATECHOL 0.6568 1.4118 NA NA
4-PYRIDOXATE NA NA 0.9242 1.0758
5,6 DIMETHYLBENZIMIDAZOLE 1.2024 0.7976 NA NA
5-Aminopentanoic acid 1.0468 0.8119 0.9835 1.1264
5^-DEOXYADENOSINE 1.2767 0.6680 NA NA
5-HYDROXYINDOLEACETATE 0.7949 1.2461 NA NA
5-HYDROXYTRYPTOPHAN 1.0646 0.9224 NA NA
6-CARBOXYHEXANOATE NA NA 0.9881 1.0119
6-HYDROXYDOPAMINE 0.8424 1.1892 NA NA
6-PHOSPHOGLUCONATE 0.9773 1.0272 NA NA
7-Hydroxy-3-oxo-Cholest-4-en-26-oic Acid 1.7133 0.1440 NA NA
7-HYDROXYOCTANOATE 0.9772 1.0273 NA NA
8-HYDROXY-DEOXYGUANOSINE 0.8253 1.2097 NA NA
ACETOACETATE 1.2872 0.6554 NA NA
ACETOIN 2.2227 0.3472 0.7075 0.6138
ADENINE 2.3049 1.5961 0.0989 0.0994
ADENOSINE 1.9154 2.0671 0.0967 0.0987
ADENOSINE-MONOPHOSPHATE 2.2382 1.5367 0.1731 0.1414
ADIPATE 2.0478 0.8965 0.6139 0.4246
Adipoyl-L-carnitine 0.9460 1.0648 NA NA
AICAR 1.1957 0.7651 NA NA
ALLANTOIN 2.0388 1.9351 0.0879 0.0941
ALPHA-KETOISOVALERATE NA NA 1.1221 0.8779
AMINOADIPATE 0.9905 0.8445 0.9132 1.2260
ARABINOSE 0.9479 1.0625 NA NA
ARABITOL 1.0291 0.9651 NA NA
ARGININE 2.1922 1.8254 0.0473 0.0726
ASCORBATE 1.1687 2.1734 0.4509 0.4026
ASPARAGINE 1.1111 0.8666 NA NA
ASPARTATE 2.6482 1.3241 0.0403 0.0415
AZELATE 1.8008 1.4364 0.3167 0.5187
BENZOATE 1.7478 1.8148 0.2718 0.3014
BENZYL ALCOHOL 0.9392 1.0729 NA NA
BETAINE 1.9589 2.0116 0.0985 0.0997
BETAINE ALDEHYDE 2.2714 1.7604 0.0524 0.0425
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE-2 1.3563 0.5724 NA NA
BIOTIN NA NA 1.2211 0.7789
BIS(2-ETHYLHEXYL)PHTHALATE 1.7543 2.4598 0.0137 0.0155
BUTANOATE 2.2909 1.6430 0.1111 0.0623
Butyrylcarnitine 0.9113 1.1064 NA NA
CAPRYLOYLGLYCINE 1.3685 0.5578 NA NA
CARNOSINE 1.7285 2.2512 0.1197 0.1091
CDP-ETHANOLAMINE 1.0937 0.8875 NA NA
Chenodeoxycholic acid 3.5634 0.1447 0.0030 0.0037
CHOLATE 3.7744 0.0669 0.0011 0.0021
CITICOLINE-1 2.0851 1.8674 0.1027 0.0894
CITRATE 1.9643 1.6351 0.2409 0.2656
CITRULLINE 2.4053 1.6177 0.0380 0.0420
CORTEXOLONE 1.2413 0.7104 NA NA
CORTISOL 0.8303 1.7658 0.6452 0.8863
Cortisone NA NA 0.8661 1.1339
CREATINE 2.1809 1.9163 0.0298 0.0257
CREATININE 2.1868 1.9421 0.0158 0.0123
Cyclic ADP-ribose 0.9861 1.0166 NA NA
CYCLIC AMP NA NA 0.9810 1.0190
CYSTATHIONINE 1.0580 0.9304 NA NA
CYTIDINE NA NA 0.8785 1.1215
CYTIDINE 2^,3^-CYCLIC PHOSPHATE-1 0.9420 1.0696 NA NA
CYTIDINE DIPHOSPHATE 1.0667 0.9200 NA NA
CYTIDINE MONOPHOSPHATE 1.7401 1.5938 0.3486 0.4164
CYTOSINE 2.1280 1.8119 0.1055 0.0899
decanoylcarnitine 1.5244 0.3707 NA NA
DEOXYADENOSINE 1.2923 0.6492 NA NA
DEOXYCARNITINE 2.5000 1.5590 0.0191 0.0151
DEOXYCHOLATE 3.7236 0.1241 0.0029 0.0034
DEOXYGUANOSINE 0.9219 1.0937 NA NA
DEOXYGUANOSINE-MONOPHOSPHATE 1.9779 1.3568 0.4189 0.3059
DEOXYURIDINE 0.9334 1.0799 NA NA
D-GLUCURONOLACTONE 0.6137 1.4636 NA NA
DIAMINOPIMELATE 1.3553 0.5736 NA NA
DIHYDROURACIL-1 1.0970 0.8836 NA NA
DIMETHYLGLYCINE 1.2919 0.6497 NA NA
DL-2-AMINOCTANOATE 1.1360 0.7733 NA NA
DOCOSAHEXAENOATE 1.8867 1.2708 0.0373 0.0587
EICOSAPENTAENOATE 2.6757 1.3652 0.0107 0.0092
ETHANOLAMINE PHOSPHATE 2.3829 1.1680 0.2353 0.2419
FAD 1.2162 0.7406 NA NA
FERULATE 1.0562 0.9325 NA NA
Fructose 1,6-bisphosphate NA NA 0.9563 1.0437
FRUCTOSE 6-PHOSPHATE 1.1065 1.7942 0.5359 0.6958
FUMARATE 2.0602 1.9936 0.0651 0.0467
GAMMA-LINOLENATE 1.4701 0.4359 NA NA
GLUCONATE 0.1166 0.1016 1.9254 1.7067
GLUCURONATE 1.6275 2.4071 0.0993 0.1006
GLUTAMATE 2.3380 1.5380 0.1016 0.1121
GLUTAMINE 1.8765 2.0991 0.1042 0.1035
GLUTARATE 3.0629 0.4974 0.2014 0.1546
GLUTATHIONE REDUCED 1.8466 2.1527 0.1053 0.0876
GLYCERALDEHYDE 3-PHOSPHATE 1.0572 0.9313 NA NA
GLYCERATE 2.1525 1.9682 0.0209 0.0197
GLYCEROL 3-PHOSPHATE 1.8125 1.4596 0.4092 0.3953
GLYCEROPHOSPHOCHOLINE 2.3883 1.5967 0.0623 0.0522
GLYCOCHENODEOXYCHOLATE 0.9604 1.0476 NA NA
GLYCOCHOLATE 2.0629 2.0636 0.0205 0.0302
Glycocholic acid hydrate 2.0604 2.0679 0.0194 0.0303
Glycohyodeoxycholic Acid 1.1514 0.8183 NA NA
GLYCOLATE 1.0482 0.9421 NA NA
GUANIDINOSUCCINATE 0.5679 3.8958 0.0119 0.0070
GUANINE-1 1.0107 0.9872 NA NA
GUANOSINE 1.6348 2.4464 0.0810 0.0789
GUANOSINE MONOPHOSPHATE 1.7816 1.5331 0.4479 0.3263
hexanoylcarnitine 1.0898 0.8923 NA NA
HEXANOYLGLYCINE 1.0486 0.9416 NA NA
HEXOSE NA NA 1.0429 0.9571
HIPPURATE 1.7442 2.4723 0.0134 0.0155
HISTIDINE 1.8759 2.2085 0.0656 0.0515
HOMOCYSTEIC 0.8227 1.2128 NA NA
HOMOGENTISATE 1.4248 0.4902 NA NA
HOMOSERINE 2.1038 1.9063 0.0676 0.0732
HYDROQUINONE 1.0191 0.9771 NA NA
HYDROXYISOCAPROIC 1.9773 1.8330 0.1587 0.1699
HYDROXYPHENYLLACTATE 1.7889 2.2261 0.0939 0.0955
HYDROXYPYRUVATE 0.8429 1.1885 NA NA
Hyodeoxycholic acid 1.6399 0.0402 NA NA
HYPOTAURINE 0.9681 1.0383 NA NA
HYPOXANTHINE 2.8215 0.8655 0.1622 0.1284
INDOLE-3-ETHANOL 0.5641 1.5231 NA NA
INOSINE 2.3296 1.3969 0.1712 0.1685
INOSINE MONOPHOSPHATE 0.6940 1.3672 NA NA
ISOCITRATE 1.0799 0.9041 NA NA
ISOLEUCINE 1.6970 2.2869 0.1103 0.1203
Isovalerylcarnitine 0.9372 1.0754 NA NA
ITACONATE 1.4938 0.6050 NA NA
KYNURENINE 0.8687 1.1576 NA NA
LACTATE 1.6136 1.7111 0.4216 0.3723
LACTOSE 0.8825 1.1410 NA NA
Lactoylglutathione NA NA 1.0231 0.9769
L-ALANINE 1.8733 1.3945 0.3796 0.4183
LAUROYLCARNITINE 1.6160 0.2608 NA NA
L-CARNITINE 2.1783 1.8192 0.0712 0.0679
LEUCINE 1.7424 2.2135 0.1103 0.1361
L-GULONOLACTONE 1.6147 2.2832 0.1737 0.1423
LINOLEATE 1.4290 0.4852 NA NA
L-ORNITHINE 2.2120 1.2307 0.2145 0.3813
LPC(16:0) 2.2147 1.9055 0.0183 0.0124
LPC(18:1) 2.5435 1.5407 0.0034 0.0026
LPE(16:0) 2.0920 2.0847 0.0025 0.0015
LPE(18:1) 1.0622 0.9254 NA NA
LUMICHROME 1.8810 1.8637 0.2012 0.1980
LYSINE 1.8257 1.5330 0.2686 0.4615
MALATE 1.6574 1.4769 0.4706 0.4746
MANDELATE 0.9109 1.1070 NA NA
METHIONINE-1 0.9732 1.0322 NA NA
METHIONINE-2 NA NA 1.1266 0.8734
METHIONINE SULFOXIDE 0.9874 1.0151 NA NA
METHYLTHIOADENOSINE 1.0183 0.9780 NA NA
Muricholic Acid 3.7458 0.1012 0.0015 0.0016
Murideoxycholic Acid 1.8028 0.0366 NA NA
N-a-Acetyl-L-arginine 1.1966 0.7640 NA NA
N-ACETYLASPARAGINE 1.1618 0.8058 NA NA
N-ACETYLASPARTATE 1.7416 2.3146 0.0919 0.0710
N-ACETYLCYSTEINE 1.5122 2.4279 0.0942 0.0528
N-ACETYLGLUTAMATE NA NA 1.0239 0.9761
N-ACETYLGLYCINE NA NA 1.0854 0.8976
N-ACETYLLEUCINE 0.9927 2.9812 0.1690 0.1873
N-ACETYLMETHIONINE 1.3806 2.8322 0.0470 0.0455
N-ACETYLNEURAMINATE 2.2569 1.7331 0.0605 0.0717
N-ACETYLPHENYLALANINE 1.2982 2.4910 0.2093 0.2501
N-ACETYLTRYPTOPHAN 1.8571 2.1938 0.0617 0.0864
NAD+ 2.1281 1.6197 0.1802 0.1753
N-ALPHA-ACETYLLYSINE 1.8970 2.0215 0.0399 0.0518
N-FORMYL-L-METHIONINE 3.0794 0.8455 0.0288 0.0205
NICOTINAMIDE-1 0.9687 1.0375 NA NA
NICOTINAMIDE-2 1.5073 1.6524 0.4591 0.4900
NICOTINAMIDE MONONUCLEOTIDE 1.2811 0.6626 NA NA
N-METHYLGLUTAMATE 1.8683 1.8050 0.2251 0.2357
N,N-DIMETHYLARGININE 2.5310 1.0503 0.2373 0.1897
N,N,N-TRIMETHYLLYSINE 1.1148 0.8623 NA NA
NORADRENALINE 0.8394 1.1927 NA NA
Nor-Desoxycholic Acid 1.3705 1.8785 0.0615 0.0261
O-ACETYLCARNITINE 1.4633 2.1756 0.2774 0.2797
O-ACETYLSERINE 2.3969 1.6518 0.0334 0.0265
octanoylcarnitine 1.2783 0.6660 NA NA
OLEATE 1.4033 0.5160 NA NA
Oleoyl-L-carnitine 1.5932 0.2881 NA NA
OMEGA-HYDROXYDODECANOATE 1.9688 2.1048 0.0558 0.0546
OPHTHALMATE-2 2.2753 1.1919 0.2395 0.3254
O-Succinyl-L-carnitine 0.8257 1.1743 NA NA
OXIDIZED GLUTATHIONE 1.8702 2.0579 0.1492 0.0991
OXOPROLINE NA NA 1.1739 0.8261
PALMITATE 1.2129 0.7445 NA NA
PALMITOYLCARNITINE 1.6924 0.1692 NA NA
PANTOTHENATE 1.6685 2.1439 0.1908 0.1874
PHENYLALANINE 1.9366 2.1780 0.0408 0.0410
PHENYLLACTATE 2.0123 2.1092 0.0287 0.0347
PHOSPHOCREATINE 0.9215 1.0942 NA NA
PHOSPHORYLCHOLINE 2.5127 1.5283 0.0246 0.0224
PIPECOLATE 2.6252 1.3702 0.0349 0.0314
PREPHENATE 0.6768 1.2585 NA NA
PROLINE 1.8456 2.3098 0.0310 0.0319
PROPIONYLCARNITINE 1.1082 0.8702 NA NA
PUTRESCINE-NH3 0.9668 1.0399 NA NA
PYRIDOXAL-PHOSPHATE 1.3604 2.3158 0.3374 0.2056
PYROCATECHOL 0.6821 1.3815 NA NA
PYROGLUTAMATE 1.6878 2.1920 0.1873 0.1315
PYRUVATE 0.8979 1.5739 0.8545 0.7693
RAFFINOSE 1.5097 2.7018 0.0504 0.0218
RIBOFLAVIN 2.3048 1.5758 0.1192 0.0961
SACCHARATE 1.5115 2.2518 0.2238 0.2215
S-ADENOSYLHOMOCYSTEINE-1 1.7923 1.9219 0.2355 0.2039
S-ADENOSYLMETHIONINE 2.2009 1.8784 0.0321 0.0349
SALICYLATE 1.0253 0.9747 NA NA
SALSOLINOL-2 0.6411 1.4307 NA NA
SARCOSINE 2.1308 1.6160 0.1940 0.1618
S-CARBOXYMETHYLCYSTEINE 0.8168 1.2198 NA NA
SEBACATE NA NA 0.7868 1.2132
SEDOHEPTULOSE-7-PHOSPHATE 1.2689 1.6726 0.6034 0.5672
SERINE 2.0839 1.6471 0.1606 0.2162
SEROTONIN 0.9902 1.0118 NA NA
Sodium glycochenodeoxycholate 0.9591 1.0491 NA NA
Sodium taurochenodeoxycholate 1.0264 0.9684 NA NA
Sodium tauroursodeoxycholate 1.0078 0.9906 NA NA
SPERMIDINE 2.1452 1.9552 0.0313 0.0275
SPERMINE 1.8561 2.3486 0.0120 0.0081
STEAROYLCARNITINE 1.4789 0.4254 NA NA
SUBERATE 1.8080 1.5928 0.3394 0.3586
SUCCINATE 2.0593 1.9737 0.0723 0.0570
TAURINE 1.6632 1.8684 0.3172 0.2959
Tauro-?-muricholic acid 0.9304 1.0835 NA NA
TETRADECANOYLCARNITINE 1.7397 0.1123 NA NA
TETRAHYDROBIOPTERIN 1.1714 3.0994 0.0441 0.0350
THIAMINE MONOPHOSPHATE 3.0987 0.8749 0.0042 0.0014
THREONINE 2.0837 1.8158 0.1227 0.1138
THYMIDINE 1.4827 2.7944 0.0087 0.0132
THYMIDINE-MONOPHOSPHATE NA NA 1.0193 0.9807
trans-2-Dodecenoyl-L-carnitine 1.6593 0.2088 NA NA
TRANS-CINNAMALDEHYDE 0.9097 1.1084 NA NA
Traumatic acid 1.0859 0.8969 NA NA
TRIGONELLINE 1.3378 2.9863 0.0039 0.0031
TRYPTOPHAN 1.9079 2.1283 0.0847 0.0672
TYROSINE NA NA 1.1484 0.8516
undecanedioic acid 2.0375 1.9713 0.0662 0.0869
URACIL-1 1.1721 0.7934 NA NA
URACIL-2 NA NA 0.7402 1.2165
URATE-1 2.1233 1.8596 0.0972 0.0632
UREA 0.8763 1.1485 NA NA
URIDINE 1.9078 2.0897 0.0895 0.0946
URIDINE 5^-DIPHOSPHATE 0.8215 1.2142 NA NA
URIDINE DIPHOSPHATE GLUCOSE 0.8800 1.1440 NA NA
URIDINE DIPHOSPHATE-N-ACETYLGLUCOSAMINE 2.1572 2.0017 0.0008 0.0072
URIDINE MONOPHOSPHATE NA NA 1.2137 0.7863
UROCANATE 0.9547 1.0679 NA NA
Ursocholic Acid 3.7130 0.0888 0.0164 0.0299
URSODEOXYCHOLATE 1.6412 0.0382 NA NA
VALINE 2.2098 1.7134 0.0872 0.1085
XANTHINE-1 1.3121 0.6255 NA NA
XANTHINE-2 NA NA 1.2589 0.7411
XANTHOSINE 2.0358 1.7853 0.1788 0.1310
XANTHURENATE 1.0617 0.9260 NA NA
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Factors:

F1Genotype:cox10-/-
F2Genotype:Cox10f/f
F3Genotype:ndufa9-/-
F4Genotype:ndufa9f/f
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