Data for (Study ST002434)
(Analysis AN003964)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 |
|---|---|---|---|---|---|
| 1-METHYLADENOSINE | 1.8819 | 1.5075 | 0.0000 | 0.9764 | 0.6438 |
| 2,6-DIAMINOHEPTANEDIOATE | 0.3214 | 1.0049 | 0.0000 | 1.8345 | 1.5422 |
| 2-AMINO-2-METHYLPROPANOATE | 1.2915 | 1.3944 | 0.0000 | 2.0357 | 0.5670 |
| 3-AMINO-4-HYDROXYBENZOIC_ACID | 1.2649 | 1.3235 | 0.0000 | 1.1797 | 1.0792 |
| 3-AMINOISOBUTANOATE | 0.7453 | 0.6862 | 0.0000 | 1.5797 | 1.7763 |
| 3-UREIDOPROPIONATE | 0.4227 | 0.6494 | 0.0000 | 3.3127 | 1.1079 |
| 4-GUANIDINOBUTANOATE | 1.3091 | 1.1220 | 0.0000 | 1.7505 | 0.9732 |
| 4-HYDROXY-L-PROLINE | 1.1986 | 1.7130 | 0.0000 | 0.9467 | 0.8393 |
| 5-AMINOPENTANOATE | 0.7516 | 2.5167 | 0.0000 | 0.5496 | 0.4577 |
| 5-METHYLTHIOADENOSINE | 1.4041 | 1.6539 | 0.0000 | 0.9753 | 0.7814 |
| 5-OXO-L-PROLINE | 1.0897 | 0.9757 | 0.0000 | 1.6811 | 1.2639 |
| ADENINE | 1.1885 | 0.8895 | 0.0000 | 1.9814 | 1.1505 |
| ADENOSINE | 1.8625 | 1.0233 | 0.0000 | 1.6130 | 0.8639 |
| ALPHA-TOCOPHEROL | 1.4519 | 1.3919 | 0.0000 | 1.0802 | 0.9671 |
| BETA-ALANINE | 1.2138 | 1.2424 | 0.0000 | 1.3633 | 1.0940 |
| BETAINE | 1.6361 | 1.6571 | 0.0000 | 0.9537 | 0.6730 |
| CARNOSINE | 1.7412 | 2.5574 | 0.0000 | 0.1245 | 0.1347 |
| CHOLESTERYL_ACETATE | 1.7806 | 1.4042 | 0.0000 | 1.2622 | 0.6994 |
| CITRULLINE | 1.2553 | 1.1227 | 0.0000 | 1.5160 | 1.1166 |
| CREATINE | 1.1968 | 1.2383 | 0.0000 | 1.3826 | 1.0971 |
| CREATININE | 1.2178 | 1.1766 | 0.0000 | 1.6424 | 1.0183 |
| CYTIDINE | 1.8273 | 1.4025 | 0.0000 | 1.0476 | 0.7851 |
| CYTOSINE | 1.7943 | 1.4113 | 0.0000 | 1.0525 | 0.7903 |
| DEOXYCARNITINE | 1.0036 | 1.1253 | 0.0000 | 1.6543 | 1.1708 |
| DEOXYCYTIDINE | 1.7175 | 1.5093 | 0.0000 | 1.0557 | 0.7290 |
| DIETHANOLAMINE | 1.3622 | 1.6134 | 0.0000 | 1.0809 | 0.7900 |
| ETHANOLAMINE | 2.0082 | 1.4221 | 0.0000 | 0.9589 | 0.7194 |
| GAMMA-LINOLENIC_ACID | 0.5770 | 0.9795 | 0.0000 | 2.1686 | 1.2727 |
| GLUCURONIC_ACID | 0.9576 | 1.4505 | 0.0000 | 1.3138 | 1.0388 |
| GLUCURONOLACTONE | 0.9576 | 1.4505 | 0.0000 | 1.3138 | 1.0388 |
| GLYCERO-3-PHOSPHOCHOLINE | 1.3190 | 1.5958 | 0.0000 | 1.3010 | 0.7192 |
| GLYCINE | 1.8707 | 1.7611 | 0.0000 | 0.7205 | 0.5683 |
| GLYCOLALDEHYDE_DIMER | 1.7434 | 1.3818 | 0.0000 | 1.0183 | 0.8623 |
| GUANIDINOACETATE | 1.1263 | 1.4658 | 0.0000 | 1.4002 | 0.8960 |
| GUANINE | 2.2597 | 1.7884 | 0.0000 | 0.6300 | 0.3917 |
| GUANOSINE | 2.3523 | 1.7495 | 0.0000 | 0.6160 | 0.3913 |
| HISTAMINE | 1.8515 | 1.6983 | 0.0000 | 0.8512 | 0.5753 |
| HYPOXANTHINE | 1.5034 | 1.3566 | 0.0000 | 1.0668 | 0.9833 |
| INOSINE | 1.8213 | 1.6811 | 0.0000 | 0.6636 | 0.7015 |
| L-ALANINE | 1.4859 | 1.3461 | 0.0000 | 1.2248 | 0.9236 |
| L-ANSERINE | 1.3477 | 1.6764 | 0.0000 | 1.3238 | 0.6129 |
| L-ARGININE | 1.2479 | 1.3977 | 0.0000 | 1.0641 | 1.0713 |
| L-ASPARAGINE | 1.6287 | 1.7472 | 0.0000 | 0.7768 | 0.6750 |
| LAUROYLCARNITINE | 0.6651 | 0.4109 | 0.0000 | 3.1052 | 1.3289 |
| L-CARNITINE | 0.9079 | 0.7946 | 0.0000 | 1.9781 | 1.3874 |
| LEUCINE | 1.5930 | 1.5581 | 0.0000 | 1.0625 | 0.7392 |
| L-GLUTAMIC_ACID | 1.0399 | 1.1997 | 0.0000 | 1.6481 | 1.0813 |
| L-GLUTAMINE | 1.0067 | 1.0545 | 0.0000 | 1.5227 | 1.3058 |
| L-HISTIDINE | 1.4627 | 1.3973 | 0.0000 | 1.0575 | 0.9676 |
| L-ISOLEUCINE | 1.5155 | 1.5784 | 0.0000 | 1.0236 | 0.7771 |
| L-LYSINE | 1.3236 | 1.5484 | 0.0000 | 1.0320 | 0.8988 |
| L-METHIONINE | 2.0290 | 1.6673 | 0.0000 | 0.7006 | 0.5929 |
| L-ORNITHINE | 0.9945 | 2.1060 | 0.0000 | 0.9216 | 0.5609 |
| L-PHENYLALANINE | 2.2608 | 1.4438 | 0.0000 | 0.8364 | 0.6326 |
| L-PROLINE | 1.8164 | 1.8564 | 0.0000 | 0.7341 | 0.4933 |
| L-SERINE | 1.7811 | 1.6857 | 0.0000 | 0.8128 | 0.6424 |
| L-THREONINE | 2.0387 | 1.5675 | 0.0000 | 0.8354 | 0.6205 |
| L-TRYPTOPHAN | 1.4847 | 1.4338 | 0.0000 | 1.3449 | 0.7764 |
| L-TYROSINE | 1.3290 | 1.4259 | 0.0000 | 1.1764 | 0.9464 |
| L-VALINE | 1.5176 | 1.6185 | 0.0000 | 1.0494 | 0.7230 |
| METHYL-GUANIDINE | 0.7755 | 0.8713 | 0.0000 | 2.2508 | 1.2405 |
| N-ACETYL-LYSINE | 0.9231 | 1.2512 | 0.0000 | 1.6853 | 1.0696 |
| NICOTINAMIDE | 1.1881 | 1.0961 | 0.0000 | 1.4626 | 1.2036 |
| N,N,N-TRIMETHYL-LYSINE | 1.0237 | 1.6451 | 0.0000 | 1.0344 | 0.9509 |
| NORLEUCINE | 0.2376 | 1.6281 | 0.0000 | 0.5625 | 1.5969 |
| O-ACETYL-CARNITINE | 0.5788 | 0.7939 | 0.0000 | 1.9474 | 1.5680 |
| PANTOTHENIC_ACID | 1.5786 | 0.7090 | 0.0000 | 2.4536 | 0.8999 |
| PYRIDOXINE | 0.9575 | 0.9990 | 0.0000 | 2.0053 | 1.1446 |
| RIBOFLAVIN | 1.5165 | 1.3248 | 0.0000 | 1.3446 | 0.8696 |
| SARCOSINE | 1.4662 | 1.7817 | 0.0000 | 1.0991 | 0.5607 |
| SEROTONINE | 1.0258 | 2.3447 | 0.0000 | 0.4054 | 0.5647 |
| TAURINE | 1.1968 | 1.1556 | 0.0000 | 1.4118 | 1.1651 |
| Thiamine | 2.2874 | 1.2328 | 0.0000 | 0.9919 | 0.7525 |
| TRIGONELLINE | 1.7696 | 2.2233 | 0.0000 | 0.3907 | 0.3215 |
| TRIMETHYLAMINE | 1.8687 | 1.2439 | 0.0000 | 1.2267 | 0.8334 |
| TYRAMINE | 1.3161 | 1.3886 | 0.0000 | 1.2619 | 0.9474 |
| URACIL | 2.3781 | 1.3826 | 0.0000 | 0.9403 | 0.5832 |
| UROCANATE | 1.4906 | 1.3238 | 0.0000 | 1.8527 | 0.6295 |
Factors:
| F1 | Genotype:CHCHD10S59L/+ | Gender:female | Stage:Symptomatic |
| F2 | Genotype:CHCHD10S59L/+ | Gender:Male | Stage:Symptomatic |
| F3 | Genotype:QC | Gender:QC | Stage:QC |
| F4 | Genotype:Wild-type | Gender:female | Stage:Symptomatic |
| F5 | Genotype:Wild-type | Gender:Male | Stage:Symptomatic |
