Data for (Study ST002435)

(Analysis AN003967)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Metabolite	F1	F2	F3	F4	F5	F6	F7	F8	F9
3-AMINO-4-HYDROXYBENZOIC_ACID	0.8082	1.0900	1.5337	0.8549	1.1698	0.7162	0.9934	1.1784	1.2103
3-METHYLADENINE	1.1918	1.2726	1.0605	1.3556	1.1231	0.4547	1.3754	0.4300	0.5161
3-UREIDOPROPIONATE	1.8827	0.2458	0.7197	0.7161	0.8756	1.4305	2.0152	0.1110	0.1916
4-AMINOBUTANOATE	1.5979	0.6758	0.9450	0.7361	0.9212	1.3157	1.7566	0.1757	0.3247
4-HYDROXY-L-PROLINE	1.3066	0.5604	2.5535	0.7698	0.8490	0.9296	2.3340	0.1541	0.2973
4-IMIDAZOLEACETIC_ACID	1.0321	0.5918	1.2745	0.5877	0.7986	0.5188	3.8428	0.2446	0.3571
5,6-DIHYDROURACIL	1.8350	0.2948	0.8117	0.7500	0.9596	1.3957	1.8145	0.1477	0.2380
5-AMINOPENTANOATE	1.0359	2.4217	0.5927	0.8975	0.9465	0.7172	1.2062	0.0811	0.5135
5-OXO-L-PROLINE	0.7024	0.5512	1.1052	0.4719	0.7884	0.5744	4.5845	0.1883	0.2878
Acetylcholine	0.7810	1.1979	0.7022	0.9275	1.4116	0.5216	1.6540	0.5389	0.9091
ADENINE	1.2671	0.9909	0.7028	1.3004	1.1913	1.1991	0.6263	0.3980	0.5539
ADENOSINE	1.1800	1.1187	0.6105	1.8633	1.1575	0.6996	0.8378	0.2730	0.4114
ADENOSINE_5^-MONOPHOSPHATE	1.2317	0.7675	1.1860	2.0789	0.8288	0.8020	0.5308	0.1977	0.6808
ALLANTOIN	1.1853	0.8432	1.2251	0.9539	1.2227	0.7325	1.5976	0.3909	0.6710
BETA-ALANINE	0.9873	0.8291	1.1506	0.9646	0.9731	1.0491	2.0915	0.2582	0.4832
BETAINE	0.9888	0.8250	1.3204	1.0312	1.2118	1.0988	1.3513	0.5487	0.5699
C10-CARNITINE	1.4342	1.1892	0.4216	1.0187	1.1572	0.8869	1.2792	0.3147	0.5374
C14-CARNITINE	0.9346	1.1088	0.5116	0.9410	1.5268	0.8472	1.1794	0.6340	0.7478
C2-CARNITINE	0.8882	0.8520	1.3587	0.8474	1.3128	0.7544	2.3306	0.2802	0.4005
C3-CARNITINE	0.7929	0.5493	0.6776	0.8126	1.1887	0.6276	3.6940	0.1298	0.1939
C4-CARNITINE	0.6923	0.5465	0.2746	0.5815	1.5461	0.4068	4.1230	0.1151	0.1737
C5-CARNITINE	1.1586	0.7055	0.6522	0.7656	0.9999	0.9363	2.7830	0.1775	0.3158
C8-CARNITINE	1.3940	1.1798	0.1601	1.1866	1.5175	0.9314	0.6469	0.3107	0.4828
CARNOSINE	0.6274	0.7039	1.0404	0.5982	0.8309	0.4004	4.6378	0.0530	0.2636
CHOLESTERYL_ACETATE	1.0392	0.8241	1.0712	0.7816	1.4273	1.0276	0.7428	1.3934	0.9330
CITRULLINE	1.0227	1.0116	0.7845	0.8788	1.1260	0.5993	2.6293	0.1394	0.4114
CREATINE	0.9580	0.8293	1.1780	0.9482	0.9455	1.0327	2.2222	0.2472	0.4706
CREATININE	1.2940	0.8914	0.9598	0.7930	1.2220	0.8275	1.6026	0.3784	0.6585
CYTOSINE	1.2264	0.6689	0.9698	0.7292	1.0421	0.9514	2.3699	0.3082	0.4523
DEOXYCARNITINE	0.9729	0.7764	1.4536	0.7250	1.1981	0.7053	2.8017	0.2092	0.2994
GAMMA-LINOLENIC_ACID	0.9173	0.3855	0.8387	0.9928	1.3408	1.1563	0.8784	1.4383	1.0756
GLYCINE	1.0369	0.5758	1.4326	0.8050	1.0468	0.8309	2.8229	0.1856	0.3268
GUANIDINOACETATE	0.9543	1.0162	1.5370	0.9469	0.8711	0.6732	2.5960	0.3032	0.3853
GUANINE	2.1744	0.6563	0.6592	0.9693	1.2425	0.8394	0.9827	0.1591	0.3406
HIPPURATE	1.0166	0.4826	0.8690	0.8822	1.5956	0.3524	2.7044	0.2266	0.4890
HISTAMINE	0.6451	1.3271	0.6513	0.8454	1.3025	1.0057	2.1878	0.1440	0.3662
L-ALANINE	1.6725	0.4617	1.1569	1.0367	1.0388	1.0212	1.7048	0.1609	0.2763
L-ANSERINE	0.3767	0.5703	0.9524	0.5737	0.7471	0.2474	5.5974	0.0605	0.1762
L-ARGININE	1.0947	0.9024	1.3797	0.7895	1.0591	0.6059	2.7471	0.0820	0.3483
L-ASPARAGINE	1.4959	0.5654	1.5560	0.9193	0.8993	0.9605	2.1255	0.1193	0.2879
LAUROYLCARNITINE	0.9524	1.0790	0.4842	0.9474	1.4774	0.8299	1.4373	0.4903	0.6621
L-CARNITINE	0.9737	0.8546	1.6621	0.8816	1.2137	0.8336	1.7757	0.4244	0.6031
LEUCINE_NORLEUCINE	1.0732	0.7173	0.9449	0.9381	1.3375	0.7715	2.0436	0.4288	0.4656
L-GLUTAMIC_ACID	0.9832	0.4810	1.8255	0.8916	0.8010	0.6715	3.5266	0.0859	0.1691
L-GLUTAMINE	1.2047	0.5822	1.5662	0.7513	0.9692	1.0710	2.3335	0.2682	0.3584
L-HISTIDINE	1.2316	0.6448	1.5038	0.8844	1.1121	0.7372	2.2799	0.1772	0.4209
L-LYSINE	1.2849	0.6181	1.4663	0.7799	1.0300	0.3728	3.2238	0.0846	0.2632
L-METHIONINE	1.3438	1.0340	1.0166	1.0219	1.2359	0.7203	1.3755	0.3059	0.5402
LPC(14:0)	0.7050	1.0124	1.0083	0.8495	1.3916	0.6497	1.0673	1.8978	1.1180
LPC(16:0)	0.7954	0.8975	1.0621	0.8947	1.3084	0.8923	0.9481	1.3294	1.1271
LPC(16:1)	0.5790	0.8605	1.4668	0.8532	1.3824	0.4622	0.9697	2.4691	1.3666
LPC(18:0)	0.8198	0.9370	0.9144	0.7747	1.3688	0.8890	0.9176	1.3603	1.1881
LPC(18:1)	0.6296	1.0104	1.2124	0.8957	1.4051	0.6103	0.9665	2.0005	1.1735
LPC(18:2)	0.8726	0.8468	1.1943	0.9716	1.3395	0.8273	1.0247	1.0096	1.0343
LPC(18:3)	1.0753	0.9764	1.3600	0.9277	1.0551	0.6899	1.4232	0.4441	1.0013
LPC(18:4)	0.5755	0.7216	1.2812	0.7018	1.8844	0.3681	1.0329	1.3003	1.5090
LPC(19:1)	1.1943	0.8845	0.5086	0.9622	1.2271	1.0486	1.0399	1.0988	0.7037
LPC(20:0)	0.4780	0.4470	2.3031	0.8748	1.3643	0.4284	0.4072	2.2887	2.0659
LPC(20:2)	0.4542	1.0075	1.3059	1.0888	1.3026	0.4413	0.8872	1.8310	1.5079
LPC(20:3)	0.6296	0.9228	1.2909	0.8981	1.4083	0.6317	1.0104	1.1301	1.3772
LPC(20:4)	0.9072	0.7674	0.8082	0.8764	1.4187	0.8213	1.2444	0.4163	1.1615
LPC(22:1)	0.5903	0.6440	1.9392	0.9216	1.4158	0.4870	0.4920	1.7956	1.7996
LPC(22:4)	0.6459	1.0574	0.8917	0.9489	1.5604	0.4669	0.8307	0.7320	1.5559
LPC(22:6)	0.8272	0.8443	0.9759	0.8978	1.4258	0.7987	1.2532	0.3275	1.1515
LPE(16:0)	0.6461	1.2900	0.8675	1.0390	1.4993	0.6396	0.7742	1.0530	1.1478
LPE(18:2)	0.4856	1.4461	0.7585	0.9315	1.4690	0.5634	1.0273	0.8445	1.2948
L-PHENYLALANINE	1.4404	0.8140	0.4587	1.1102	1.4803	0.9460	0.6094	0.5018	0.7154
L-PROLINE	1.4438	0.6289	1.2067	0.9806	1.1080	0.9789	1.7349	0.1918	0.3662
L-SERINE	1.1593	0.5870	1.8549	0.8483	1.0044	0.7781	2.5680	0.1979	0.3304
L-THREONINE	1.3056	0.5795	1.3590	0.9381	1.0307	0.7808	2.3754	0.1572	0.3496
L-TRYPTOPHAN	1.3279	1.0355	0.5037	0.9883	1.3385	1.1100	1.1696	0.2137	0.4022
L-TYROSINE	1.1985	0.7048	0.9178	1.1911	1.2161	0.6720	1.7127	0.3409	0.5945
L-VALINE	1.0558	0.6161	1.0958	0.7900	1.1048	0.7139	2.8286	0.2974	0.4037
METHYLGUANIDINE	1.8982	0.7903	0.8329	1.0351	1.4531	0.8747	0.3301	0.3036	0.6144
N-ACETYLPUTRESCINE	1.2980	0.8602	1.7507	0.9721	0.9981	0.6941	1.6677	0.4776	0.5847
NALPHA-ACETYL-L-LYSINE	1.0282	0.4608	0.8688	0.7625	1.2134	0.8084	2.6393	0.2048	0.5941
NEPSILON,NEPSILON,NEPSILON-TRIMET	1.3225	0.4355	1.6598	0.7184	1.0317	1.0032	2.5288	0.1285	0.2539
NICOTINAMIDE	0.7700	0.9891	0.6795	1.2079	1.2480	1.0927	0.9971	0.8605	0.8067
N(PAI)-METHYL-L-HISTIDINE	0.3560	1.1356	1.1370	0.5209	1.0692	0.0477	4.2372	0.0660	0.2767
O-ACETYL-L-CARNITINE	0.8798	0.8424	1.3467	0.8333	1.2928	0.7460	2.4200	0.2810	0.3944
PAF-C16	0.8823	0.8800	1.0188	0.8148	1.4740	0.6916	1.0488	1.0188	1.1813
PAF-C18	0.4179	0.3801	2.1012	0.8261	1.4811	0.3147	0.4280	2.3472	2.2420
PANTOTHENIC_ACID	1.2861	0.6311	0.9654	0.5641	1.0567	0.6611	3.3434	0.1021	0.1843
PC(21:0)	0.9117	0.5218	0.5734	0.7588	1.4365	1.3098	0.8117	1.4901	1.0672
PC(25:0)	0.5183	0.7142	0.5258	0.7668	1.1905	1.2973	1.0576	2.3443	1.1807
PC(30:0)	0.8500	1.1015	0.7898	1.0507	1.3620	0.8044	0.7290	1.0567	1.0984
PC(31:0)	0.8658	1.0806	0.5756	1.0588	1.3534	1.0052	0.6448	0.6679	1.1118
PC(32:0)	0.8684	1.0525	0.5988	0.9171	1.3699	1.2307	0.6611	0.7674	0.9871
PC(32:1)	0.5601	0.8424	1.3806	1.0242	1.3048	0.5981	0.5755	2.5103	1.4766
PC(32:2)	0.5899	0.8011	1.5831	1.0187	1.3774	0.6217	0.5246	2.1814	1.4569
PC(33:0)	0.7033	1.2308	0.7073	1.0330	1.1658	0.9580	0.8193	1.0389	1.1658
PC(33:2)	0.8256	0.8883	0.9569	1.1476	1.2954	0.7838	0.5451	0.9000	1.4083
PC(34:1)	0.7416	1.0644	1.2484	0.9719	1.2797	0.6948	0.6884	1.6902	1.2628
PC(34:2)	0.9464	0.8328	1.1456	1.0359	1.3306	0.8285	0.5759	1.0277	1.2587
PC(34:3)	0.7075	0.7796	1.4736	1.0285	1.3201	0.6891	0.5420	1.4327	1.5371
PC(35:1)	0.8444	1.2059	0.9092	1.0260	1.1901	0.6980	0.7254	1.3385	1.2311
PC(35:2)	0.9622	0.9970	0.8446	1.0940	1.2061	0.7341	0.6557	1.0021	1.3024
PC(35:3)	0.8143	0.8875	1.1509	1.1543	1.2802	0.6859	0.5720	1.0672	1.4162
PC(36:1)	0.8785	1.0512	0.9565	0.9219	1.2597	0.7354	0.7435	1.4001	1.2693
PC(36:2)	0.9196	0.9545	0.9495	0.9654	1.2990	0.7561	0.6806	1.1140	1.3177
PC(36:3)	0.7330	0.9421	1.0798	1.0514	1.4196	0.5569	0.6078	1.3133	1.4785
PC(36:4)	0.9723	0.6643	0.6957	0.9651	1.4864	0.7055	0.5590	0.5213	1.6490
PC(36:5)	0.7964	0.8290	1.0490	1.0235	1.3260	0.6900	0.6973	0.7740	1.5638
PC(37:4)	0.9788	0.7829	0.5407	0.9915	1.5109	0.6871	0.5405	0.4339	1.5955
PC(38:2)	0.6174	0.8185	1.2334	1.0252	1.2912	0.4392	0.5506	1.7922	1.8437
PC(38:5)	0.7022	0.9383	0.9045	0.9999	1.4758	0.5556	0.6239	0.6400	1.7087
PC(38:6)	0.7375	0.8504	0.9029	1.0183	1.4940	0.5944	0.6190	0.5144	1.6994
PC(40:6)	0.7916	0.9293	0.6579	0.8155	1.4867	0.6335	0.6975	0.3749	1.7945
PC(40:7)	0.4910	1.2135	0.7604	0.9188	1.4703	0.4484	0.7374	0.4835	1.8974
PC(8:0)	0.9440	0.6068	1.2170	0.9460	1.4420	0.8255	1.3111	0.9001	0.8748
PC(O-12:0/2:0)	0.7902	1.1860	1.3626	0.8479	1.2921	0.7934	0.9541	1.8709	0.8628
PC(O-14:0/2:0)	0.8070	0.9075	1.1288	0.8943	1.3758	0.7764	0.7900	1.5051	1.2148
PC(O-14:1/2:0)	0.5447	0.9314	1.5380	0.8976	1.3080	0.4886	1.0385	2.5616	1.2685
PC(O-16:1/2:0)	0.7310	0.9353	1.5339	0.9526	1.4296	0.5723	0.8421	1.6782	1.1784
PC(O-16:2/2:0)	0.8872	0.7934	1.1722	0.9959	1.3967	0.8391	0.8261	0.9299	1.1410
PC(O-16:3/2:0)	0.9454	1.0522	1.1342	0.7262	1.6735	0.7392	0.8230	1.0549	0.9621
PC(O-18:2/2:0)	0.4971	0.9564	1.2915	1.0209	1.4217	0.4546	1.1447	1.2438	1.3960
PC(O-18:3/2:0)	0.7573	1.1041	1.2102	0.7211	1.9442	0.5091	1.2643	0.9612	0.7492
PC(O-18:4/2:0)	0.9844	0.7136	0.7945	0.8368	1.4736	0.8386	1.2708	0.2795	1.1099
PC(O-20:4/2:0)	0.7042	0.9399	0.5787	0.7904	1.6807	0.5118	0.8773	0.5189	1.6757
PC(O-20:6/2:0)	0.7022	0.7108	0.7508	0.7492	1.3580	0.7456	2.1253	0.2628	1.0646
PHOSPHOCHOLINE	0.9378	0.1904	2.4495	0.9512	0.5744	0.6606	3.9642	0.0971	0.1233
REICHSTEINS_SUBSTANCE_S	0.8929	2.6076	0.2836	0.7872	1.1374	0.6096	0.6123	0.1609	1.0469
SARCOSINE	1.7095	0.5230	1.8297	0.9534	0.9250	1.4589	0.6351	0.4487	0.5150
SM(32:1)	1.0347	1.1900	0.7893	0.8472	1.5277	0.8960	0.7340	0.8228	0.8485
SM(32:2)	0.7737	1.2397	1.0171	0.8215	1.4766	0.5065	0.8833	1.2746	1.2274
SM(33:1)	1.3129	1.1376	0.6859	0.8750	1.4099	1.0952	0.6269	0.6423	0.6515
SM(34:0)	1.0903	1.2747	0.5180	0.9050	1.4429	0.9394	0.7399	0.4842	0.8609
SM(34:1)	1.0875	1.2698	0.5321	0.8983	1.4389	0.9382	0.7513	0.4911	0.8655
SM(34:2)	0.9783	1.1342	0.8535	0.9573	1.3888	0.8240	0.5635	0.9945	1.1164
SM(35:1)	1.2747	1.1888	0.3602	0.8544	1.4235	1.0493	0.9132	0.2689	0.6426
SM(36:1)	1.4004	1.2875	0.3653	0.8532	1.4192	1.2389	0.5634	0.2960	0.5347
SM(36:2)	1.3042	1.1929	0.5541	0.7995	1.6264	1.0399	0.5330	0.5004	0.6719
SM(38:1)	1.0390	0.8603	0.7548	1.0519	1.4095	0.9917	0.7084	0.5519	0.9319
SM(38:2)	1.1590	0.9958	0.8760	0.9573	1.3670	0.8957	0.7284	0.6792	0.8711
SM(39:1)	0.6985	0.4782	1.6975	1.4600	1.1146	0.5950	0.3958	1.2402	1.5909
SM(40:2)	0.6922	0.6857	1.4233	1.2054	1.3761	0.5635	0.3883	1.2120	1.6985
SM(40:3)	0.5466	0.6349	1.5392	1.1217	1.2701	0.3695	0.4326	1.9382	1.8804
SM(41:2)	1.1291	1.1163	0.7842	1.0834	1.2867	0.9331	0.6306	0.6216	0.9062
SM(42:2)	1.0870	1.1793	0.5964	1.0943	1.2305	0.9587	0.8860	0.4381	0.8219
SM(42:3)	1.0831	1.1777	0.7501	1.0520	1.2817	0.8511	0.6216	0.7102	1.0176
SN-GLYCERO-3-PHOSPHOCHOLINE	0.9655	0.6730	2.1326	0.8406	1.2066	0.6854	2.4358	0.1994	0.3872
SPERMIDINE	0.4583	1.0305	0.5459	1.2849	1.2051	1.1064	2.0380	0.4198	0.4026
TAURINE	0.8858	0.6081	1.2438	0.9677	1.2977	0.6694	2.6316	0.2537	0.3754
Thiamine	2.1656	0.3404	0.0574	0.7232	0.6936	2.8314	0.3659	0.0196	0.0371
THYMINE	0.9380	0.9138	0.8099	0.7438	0.9790	0.6680	2.6298	0.5538	0.6726
TRIGONELLINE	1.8071	0.9281	1.2516	0.7419	1.1273	0.6783	1.1786	0.4823	0.6317
URACIL	1.2605	0.4677	0.6065	0.9820	1.4604	1.6592	1.1675	0.1367	0.2257
URIDINE	1.2954	0.4481	0.5418	1.0076	1.4488	1.7546	1.0616	0.1211	0.1956
UROCANATE	0.5476	0.2878	1.1397	0.6015	1.4529	0.2650	4.3438	0.2242	0.3183

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Factors:

F1	Genotype:CHCHD10S59L/+ | Gender:female | Stage:Pre-symptomatic
F2	Genotype:CHCHD10S59L/+ | Gender:female | Stage:Symptomatic
F3	Genotype:CHCHD10S59L/+ | Gender:Male | Stage:Pre-symptomatic
F4	Genotype:CHCHD10S59L/+ | Gender:Male | Stage:Symptomatic
F5	Genotype:QC | Gender:QC | Stage:QC
F6	Genotype:Wild-type | Gender:female | Stage:Pre-symptomatic
F7	Genotype:Wild-type | Gender:female | Stage:Symptomatic
F8	Genotype:Wild-type | Gender:Male | Stage:Pre-symptomatic
F9	Genotype:Wild-type | Gender:Male | Stage:Symptomatic