Data for (Study ST002451)
(Analysis AN003999)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| Aspartic acid | 1.0799 | 0.9069 | 1.0206 | 0.9172 |
| Aspartic acid_13C_1 | 0.9177 | 0.9923 | 1.0104 | 1.1336 |
| Aspartic acid_13C_2 | 0.8392 | 1.2818 | 0.9192 | 1.1410 |
| Aspartic acid_13C_3 | 0.7054 | 1.4259 | 0.9024 | 1.2604 |
| Aspartic acid_13C_4 | NA | NA | NA | NA |
| beta-Alanine | 1.0034 | 0.9848 | 1.0142 | 0.9928 |
| beta-Alanine_13C_1 | NA | -6.9156 | NA | NA |
| beta-Alanine_13C_2 | NA | NA | NA | NA |
| beta-Alanine_13C_3 | 1.1335 | 1.2368 | 0.7661 | 0.8297 |
| Citric acid | 1.2411 | 0.9563 | 0.9586 | 0.7851 |
| Citric acid_13C_1 | 0.7092 | 0.9365 | 1.1783 | 1.2644 |
| Citric acid_13C_2 | 0.9067 | 1.0207 | 1.0408 | 1.0492 |
| Citric acid_13C_3 | 0.5740 | 1.0886 | 1.1412 | 1.2852 |
| Citric acid_13C_4 | 0.8727 | 1.1041 | 0.7334 | 1.3420 |
| Citric acid_13C_5 | NA | 1.0899 | 2.2792 | 4.3121 |
| Citric acid_13C_6 | NA | NA | NA | NA |
| Ethanolamine | 1.0012 | 0.9983 | 1.0004 | 1.0002 |
| Ethanolamine_13C_1 | NA | NA | NA | NA |
| Ethanolamine_13C_2 | NA | NA | NA | NA |
| Fumaric acid | 1.1120 | 0.9380 | 1.0204 | 0.9224 |
| Fumaric acid_13C_1 | 0.7910 | 1.7409 | 0.5618 | 0.8303 |
| Fumaric acid_13C_2 | 0.6698 | 0.9986 | 1.1039 | 1.2751 |
| Fumaric acid_13C_3 | 0.6348 | 1.4286 | 0.8472 | 1.0804 |
| Fumaric acid_13C_4 | -0.5954 | NA | NA | NA |
| Glutamic acid | 1.1153 | 0.8678 | 0.9499 | 0.9690 |
| Glutamic acid_13C_1 | 0.8810 | 1.1120 | 1.1825 | 0.8030 |
| Glutamic acid_13C_2 | 0.9472 | 1.0524 | 0.9728 | 1.1253 |
| Glutamic acid_13C_3 | 0.8261 | 1.2677 | 1.0884 | 0.9300 |
| Glutamic acid_13C_4 | 0.2034 | 1.5574 | 1.2423 | 1.8965 |
| Glutamic acid_13C_5 | NA | NA | NA | NA |
| Glycine | 0.9976 | 1.0243 | 0.9886 | 0.9998 |
| Glycine_13C_1 | NA | NA | NA | NA |
| Glycine_13C_2 | NA | NA | NA | NA |
| Glyoxylic acid | 1.0403 | 0.9864 | 0.9933 | 0.9819 |
| Glyoxylic acid_13C_1 | 0.2971 | 1.3961 | 0.9668 | 1.2834 |
| Glyoxylic acid_13C_2 | NA | NA | NA | NA |
| Isoleucine | 1.0046 | 0.9972 | 1.0013 | 0.9952 |
| Isoleucine_13C_1 | NA | NA | NA | NA |
| Isoleucine_13C_2 | NA | NA | NA | NA |
| Isoleucine_13C_3 | 0.6625 | 1.2650 | 0.9126 | 1.2385 |
| Isoleucine_13C_4 | 1.9613 | 0.1262 | 1.4271 | 0.2619 |
| Isoleucine_13C_5 | 0.9542 | 0.9693 | 1.0501 | 1.0523 |
| Isoleucine_13C_6 | 6.3023 | 0.8797 | NA | NA |
| Lactic acid | 1.2184 | 1.0101 | 0.9377 | 0.7679 |
| Lactic acid_13C_1 | 2.0000 | 0.6663 | 0.0890 | 1.1744 |
| Lactic acid_13C_2 | 0.7619 | 0.6852 | 1.1940 | 1.5108 |
| Lactic acid_13C_3 | 0.6380 | 1.0125 | 1.1159 | 1.3309 |
| Leucine | 0.9960 | 1.0037 | 1.0009 | 0.9993 |
| Leucine_13C_1 | NA | NA | NA | NA |
| Leucine_13C_2 | NA | NA | NA | NA |
| Leucine_13C_3 | 1.0963 | 0.9720 | 0.8053 | 1.1632 |
| Leucine_13C_4 | 1.3577 | 1.1172 | 0.8949 | 0.3873 |
| Leucine_13C_5 | 0.9774 | 0.8714 | 0.9716 | 1.2817 |
| Leucine_13C_6 | 3.3914 | 0.2476 | 0.2063 | NA |
| Malic acid | 1.1903 | 0.9243 | 0.9260 | 0.9430 |
| Malic acid_13C_1 | NA | 1.4413 | 1.7995 | 1.0842 |
| Malic acid_13C_2 | 0.6664 | 1.0612 | 1.1587 | 1.1526 |
| Malic acid_13C_3 | 1.3840 | 1.5101 | NA | 2.3455 |
| Malic acid_13C_4 | NA | NA | NA | NA |
| Phenylalanine | 1.0109 | 0.9887 | 1.0019 | 0.9983 |
| Phenylalanine_13C_1 | NA | 3.1212 | 1.6925 | NA |
| Phenylalanine_13C_2 | NA | NA | NA | NA |
| Phenylalanine_13C_3 | 1.0809 | 0.9151 | 0.9659 | 1.0451 |
| Phenylalanine_13C_4 | 1.1461 | 0.8760 | 1.0993 | 0.8546 |
| Phenylalanine_13C_5 | NA | NA | NA | NA |
| Phenylalanine_13C_6 | 0.6594 | 1.6024 | 0.3087 | 1.4576 |
| Phenylalanine_13C_7 | 0.6199 | 1.2309 | 0.9281 | 1.2828 |
| Phenylalanine_13C_8 | 0.9310 | 0.7432 | 1.3586 | 1.0161 |
| Phenylalanine_13C_9 | 0.6110 | 1.5235 | 0.6891 | 1.1833 |
| Pyroglutamic acid | 1.0435 | 1.0080 | 0.9914 | 0.9545 |
| Pyroglutamic acid_13C_1 | 0.9025 | 1.1029 | 1.2193 | 0.8378 |
| Pyroglutamic acid_13C_2 | 0.6847 | 1.0409 | 0.9939 | 1.2787 |
| Pyroglutamic acid_13C_3 | 0.5779 | 0.5343 | 1.3869 | 1.6115 |
| Pyroglutamic acid_13C_4 | NA | 0.7033 | 0.3189 | 3.0010 |
| Pyroglutamic acid_13C_5 | 4.9027 | NA | NA | NA |
| Pyruvic acid | 1.0612 | 1.0164 | 0.9729 | 0.9383 |
| Pyruvic acid_13C_1 | NA | NA | NA | NA |
| Pyruvic acid_13C_2 | NA | NA | NA | NA |
| Pyruvic acid_13C_3 | 0.9545 | 0.9777 | 1.0332 | 1.0443 |
| Serine | 1.0052 | 0.9846 | 1.0027 | 1.0126 |
| Serine_13C_1 | NA | -5.2254 | NA | NA |
| Serine_13C_2 | NA | NA | NA | NA |
| Serine_13C_3 | 1.7573 | 0.0432 | 0.8440 | 1.5376 |
| Urea | 1.0200 | 1.0006 | 0.9885 | 0.9879 |
| Urea_13C_1 | 0.7054 | 0.9910 | 1.1697 | 1.1774 |
Factors:
| F1 | Group:E3_control | APOE genotype:E3/E3 | Treatment:Control |
| F2 | Group:E3_proinflammatory | APOE genotype:E3/E3 | Treatment:Proinflammatory |
| F3 | Group:E4_control | APOE genotype:E4/E4 | Treatment:Control |
| F4 | Group:E4_proinflammatory | APOE genotype:E4/E4 | Treatment:Proinflammatory |
