Data for (Study ST002457)
(Analysis AN004009)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 |
---|---|---|---|
10-HAD | 1.0870 | 0.8248 | 1.1648 |
10-Hydroxydecanoic acid | 0.9791 | 0.8113 | 1.2777 |
14-Methylhexadecanoic acid | 0.9700 | 1.0382 | 0.9737 |
1-Aminocyclopropanecarboxylate | 0.8504 | 1.0928 | 1.0033 |
1-Methyladenosine | 0.9820 | 1.1875 | 0.7580 |
2,4-Dihydroxypteridine | 1.3134 | 0.8803 | 0.8903 |
2-Acetamido-2-Deoxy-Beta-D-Glucosylamine | 0.7688 | 0.8494 | 1.4093 |
2-Aminoadipate | 0.6014 | 1.3529 | 0.8635 |
2-Aminoisobutyrate | 0.7668 | 1.1448 | 1.0049 |
2-Aminophenol | 0.8779 | 1.1008 | 0.9577 |
2^-Deoxy-5^-Adenosine Monophosphate (dAMP) | 1.4457 | 0.5295 | 1.2570 |
2-hydroxy glutarate | 1.1613 | 0.9627 | 0.9101 |
2-Hydroxyhexadecanoic acid | 1.0684 | 0.9625 | 0.9918 |
2-Methylmaleate | 0.9948 | 1.0191 | 0.9783 |
2-Phosphoglycerate | 0.6339 | 1.3088 | 0.8957 |
3-(2-Hydroxyphenyl)Propanoate | 0.9990 | 0.7358 | 1.3641 |
3-(4-Hydroxyphenyl)Pyruvate | 0.4409 | 1.0949 | 1.3587 |
3-Hydroxybutanoate | 0.9206 | 1.0437 | 1.0094 |
3-hydroxybutyric acid | 0.8285 | 1.0368 | 1.0994 |
3-Hydroxymethylglutarate | 0.8841 | 0.9526 | 1.1667 |
3-Hydroxyoctanoic acid | 0.9351 | 0.9578 | 1.1148 |
3-Methyl-2-Oxovalerate | 0.8344 | 1.0358 | 1.0957 |
3-Methyl-L-Histidine | 0.7510 | 1.0986 | 1.0823 |
4-Acetamidobutanoate | 0.5894 | 1.1854 | 1.1043 |
4-Guanidinobutanoate | 0.8728 | 1.0973 | 0.9776 |
4-Imidazoleacetate | 0.7924 | 0.9742 | 1.2171 |
4-Pyridoxate | 0.9475 | 1.1324 | 0.8639 |
5-Aminolevulinate | 1.5156 | 0.8328 | 0.7788 |
5-Hydroxylysine | 0.4581 | 1.0841 | 1.3585 |
5-Methylcytosine | 0.8399 | 1.1161 | 0.9805 |
5(Z),8(Z),11(Z)-Eicosatrienoic Acid | 1.0125 | 1.0488 | 0.9220 |
6-Carboxyhexanoate | 1.2240 | 1.1388 | 0.5622 |
9-Decenoic acid | 1.0356 | 1.0378 | 0.9169 |
Acetylcholine | 0.7815 | 0.9712 | 1.1973 |
Acetyl CoA | 0.9443 | 1.1507 | 0.8415 |
Acetyl-L-carnitine | 0.9017 | 1.0820 | 0.9733 |
Adenine | 0.8378 | 1.0878 | 1.0213 |
Adenosine | 1.3657 | 0.6428 | 1.1712 |
Adenosine 3^,5^-cyclic monophosphate (cAMP) | 1.0028 | 1.0983 | 0.8624 |
Adenosine 5^-Diphosphate (ADP) | 0.9701 | 1.0586 | 0.9457 |
Adenosine 5^-triphosphate (ATP) | 0.9179 | 1.2194 | 0.7702 |
Adenosine Diphosphate Ribose | 0.9771 | 1.0821 | 0.9071 |
Adenosine-Monophosphate (AMP) | 1.0409 | 0.9147 | 1.0815 |
Adp-Glucose | 1.0482 | 1.0117 | 0.9418 |
AICAR | 1.0821 | 0.9295 | 1.0252 |
Alanine | 0.8942 | 1.0712 | 0.9947 |
Alanine-IS | 0.9968 | 0.9995 | 1.0035 |
Allantoin | 0.7848 | 1.0773 | 1.0820 |
all-cis-4,7,10,13,16-Docosapentaenoic acid | 0.8982 | 1.0703 | 0.9923 |
Allothreonine | 0.8929 | 1.0689 | 0.9991 |
Alpha-Hydroxyisobutyrate | 0.9073 | 1.0053 | 1.0738 |
Aminoisobutanoate | 0.8002 | 1.1153 | 1.0163 |
Arachidic acid | 0.9020 | 1.1984 | 0.8129 |
Arachidonic acid | 0.9836 | 1.0115 | 0.9984 |
Arginine | 0.8838 | 1.1117 | 0.9481 |
Argininosuccinate | 0.8833 | 1.0699 | 1.0059 |
Asparagine | 0.9589 | 0.9769 | 1.0677 |
Aspartate | 0.8347 | 1.1679 | 0.9138 |
Behenic acid | 0.3994 | 1.4588 | 0.8796 |
Beta-Alanine | 0.8570 | 0.9862 | 1.1441 |
Beta-Glycerophosphate | 0.7523 | 1.1782 | 0.9717 |
beta-Hydroxyisovaleric acid | 0.9885 | 0.8758 | 1.1809 |
Betaine | 1.2191 | 0.9476 | 0.8804 |
Beta-Nicotinamide Adenine Dinucleotide | 0.7783 | 1.1654 | 0.9666 |
Butyryl-L-carnitine | 1.1875 | 0.8829 | 0.9969 |
Carnitine | 0.9370 | 1.0354 | 1.0064 |
Carnosine | 0.9930 | 1.1773 | 0.7623 |
CDP-Ethanolamine | 1.1317 | 0.9265 | 0.9858 |
cis-11-Eicosenoic acid | 1.1276 | 0.9909 | 0.9008 |
Cis-4-Hydroxy-D-Proline | 0.6858 | 1.0882 | 1.1536 |
cis-5-Dodecenoic acid | 1.0782 | 0.9422 | 1.0110 |
cis-7,10,13,16-Docosatetraenoic acid | 0.9014 | 1.1027 | 0.9450 |
cis-Aconitate | 0.8184 | 1.1475 | 0.9561 |
Citicoline | 0.8919 | 0.9399 | 1.1773 |
Citrate | 0.8663 | 1.0522 | 1.0452 |
Citrulline | 0.6399 | 1.2680 | 0.9466 |
Coenzyme A | 1.0101 | 1.0263 | 0.9549 |
Corticosterone | 0.5073 | 1.2367 | 1.0441 |
Creatine | 0.9111 | 1.0633 | 0.9907 |
Creatinine | 0.7480 | 1.1634 | 0.9958 |
Cyclic AMP | 1.0449 | 1.0239 | 0.9278 |
Cystathionine | 0.6134 | 1.3167 | 0.9028 |
Cystine | 0.6712 | 0.8364 | 1.5126 |
Cytidine | 1.1896 | 0.8635 | 1.0218 |
Cytidine 2^,3^-Cyclic Phosphate | 0.4700 | 1.7178 | 0.0503 |
Cytidine Diphosphate (CDP) | 0.9389 | 1.1491 | 0.8485 |
Cytidine Monophosphate (CMP) | 1.3610 | 0.8880 | 0.8381 |
Decanoic acid | 1.0883 | 0.8156 | 1.1762 |
Deoxycarnitine | 1.0588 | 0.9457 | 1.0232 |
Deoxycytidine | 0.7349 | 1.2509 | 0.8869 |
Deoxycytidine-Diphosphate (dCDP) | 0.5975 | 1.1561 | 1.1164 |
Deoxycytidine Monophosphate (dCMP) | 1.5673 | 0.7778 | 0.8091 |
Deoxyguanosine | 1.3657 | 0.6428 | 1.1712 |
Deoxyguanosine diphosphate (dGDP) | 0.9670 | 1.0711 | 0.9312 |
Deoxyguanosine-Monophosphate (dGMP) | 1.0409 | 0.9147 | 1.0815 |
Deoxyguanosine triphosphate (dGTP) | 0.9326 | 1.2033 | 0.7794 |
Deoxyribose | 0.9076 | 0.9166 | 1.1955 |
Deoxyuridine | 0.6301 | 1.0729 | 1.2234 |
Dethiobiotin | 0.7333 | 1.1078 | 1.0852 |
D-Glucosamine 6-phosphate | 1.2208 | 0.8823 | 0.9686 |
Dihydrobiopterin | 1.1642 | 0.9077 | 0.9832 |
Dihydronicotinamide-adenine dinucleotide phosphate (NADPH) | 0.8242 | 1.4058 | 0.5959 |
Dihydroorotate | 1.0276 | 1.0818 | 0.8633 |
Dihydroxyacetone Phosphate (DHAP) | 1.2683 | 0.8851 | 0.9232 |
Dimethylarginine | 0.6561 | 1.1930 | 1.0356 |
Dimethylglycine | 0.9295 | 0.9856 | 1.0816 |
Docosahexaenoic Acid | 0.9369 | 1.0568 | 0.9771 |
Docosatrienoic Acid | 0.9999 | 1.2602 | 0.6655 |
D-Ribose 5-Phosphate | 1.2466 | 0.8289 | 1.0195 |
D-Sedoheptulose | 0.8621 | 0.9965 | 1.1254 |
Eicosapentaenoate | 0.9860 | 0.9477 | 1.0842 |
Erucic acid | 0.9282 | 1.1609 | 0.8416 |
FAD (Flavin adenine dinucleotide) | 1.0237 | 1.0166 | 0.9565 |
Fructose 6-Phosphate | 0.8494 | 1.0454 | 1.0693 |
Galactosamine | 1.0404 | 0.9883 | 0.9807 |
Galactose 1-Phosphate | 0.8430 | 1.0506 | 1.0679 |
Galacturonate | 0.2396 | 1.0548 | 1.5899 |
gamma-Glutamylcysteine | 0.6166 | 0.9971 | 1.3395 |
Glucosamine | 1.0395 | 0.9886 | 0.9811 |
Glucose | 1.0167 | 0.9884 | 1.0013 |
Glucose 6-Phosphate | 0.8646 | 1.0512 | 1.0481 |
Glucose-IS | 0.9947 | 1.0028 | 1.0008 |
Glutamate | 0.9010 | 1.0532 | 1.0135 |
Glutamate -IS | 1.0255 | 0.9799 | 1.0054 |
Glutamine | 0.7884 | 1.2088 | 0.8981 |
Glutamine - IS | 1.0882 | 0.9261 | 1.0244 |
Glutarate | 0.7253 | 1.1012 | 1.1012 |
Glutarylcarnitine | 0.3861 | 1.4226 | 0.9560 |
Glutathione disulfide (GSSG) | 1.5044 | 0.8256 | 0.7985 |
Glutathione Reduced (GSH) | 1.0384 | 1.0712 | 0.8685 |
Glyceraldehyde 3-phosphate | 1.6522 | 0.7045 | 0.8356 |
Glycerol | 0.9367 | 0.9521 | 1.1213 |
Glycerol 3-Phosphate | 0.7473 | 1.1795 | 0.9744 |
Glycine | 0.9145 | 0.9961 | 1.0801 |
Glycolate | 1.0036 | 0.9979 | 0.9996 |
Guadinoacetate | 0.7484 | 1.1558 | 1.0059 |
Guanidinoacetate | 0.7484 | 1.1558 | 1.0059 |
Guanidinosuccinate | 0.2302 | 1.2159 | 1.2805 |
Guanine | 1.1683 | 0.9247 | 0.9563 |
Guanosine | 1.3370 | 0.7177 | 1.0934 |
Guanosine Diphosphate (GDP) | 0.8508 | 1.1144 | 0.9732 |
Guanosine Diphosphate Mannose | 1.0396 | 0.9905 | 0.9783 |
Guanosine Monophosphate (GMP) | 1.1315 | 0.9627 | 0.9362 |
Gulonolactone | 0.4746 | 1.2621 | 1.0993 |
Hippurate | 0.9947 | 0.9931 | 1.0141 |
Histamine | 0.8503 | 1.2133 | 0.8377 |
Histidine | 0.9446 | 0.9006 | 1.1852 |
Homocysteine | 0.6906 | 1.3511 | 0.7879 |
Homoserine | 0.8929 | 1.0689 | 0.9991 |
Hydroxyproline | 0.6858 | 1.0882 | 1.1536 |
Hypotaurine | 1.0521 | 0.9472 | 1.0270 |
Hypoxanthine | 1.1870 | 0.9028 | 0.9700 |
Indoxyl Sulfate | 1.1071 | 0.8297 | 1.1405 |
Inosine | 1.2327 | 0.8006 | 1.0706 |
Inosine-Monophosphate (IMP) | 1.2634 | 0.8269 | 1.0076 |
Isoleucine | 0.7610 | 1.0713 | 1.1111 |
Kynurenate | 0.4112 | 1.4736 | 0.8640 |
Kynurenine | 0.8486 | 1.0224 | 1.1017 |
Lactate | 1.0484 | 0.9866 | 0.9761 |
Lactate -IS | 1.0062 | 0.9973 | 0.9983 |
Lauric acid | 1.8403 | 0.6242 | 0.7815 |
Lauroylcarnitine | 0.8000 | 1.1324 | 0.9930 |
L-Cysteic Acid | 0.9969 | 0.9733 | 1.0394 |
L-Dopa (3,4-Dihydroxyphenylalanine) | 1.4027 | 0.9817 | 0.7231 |
Leucine | 0.8597 | 0.9622 | 1.1747 |
Lignoceric acid | 0.6299 | 1.4082 | 0.7625 |
Linoleic acid | 1.2649 | 0.9422 | 0.8476 |
Linolenic acid | 1.4086 | 0.8117 | 0.9014 |
Lumichrome | 0.9954 | 0.8111 | 1.3015 |
Lysine | 0.8913 | 1.0120 | 1.0786 |
Malate | 0.9278 | 0.9742 | 1.0987 |
Mannitol/Sorbitol | 0.2331 | 0.3179 | 2.6089 |
Methionine | 0.8634 | 1.0698 | 1.0235 |
Methylarginine | 0.8017 | 1.0775 | 1.0669 |
Methyl Galactoside | 1.5073 | 0.5967 | 1.1107 |
Methylthioadenosine | 1.0085 | 0.9877 | 1.0095 |
Methyl Vanillate | 1.0909 | 0.9090 | 1.0455 |
Mevalonate | 0.7437 | 0.9536 | 1.2881 |
Monoethylmalonate | 1.1571 | 0.9116 | 0.9841 |
Myo-Inositol | 0.9532 | 1.0170 | 1.0176 |
Myristic acid | 0.9661 | 0.9924 | 1.0401 |
Myristoleic acid | 1.1301 | 0.7849 | 1.1819 |
Myristoyl-carnitine | 0.8688 | 1.1283 | 0.9384 |
N6-(Delta2-Isopentenyl)-Adenine | 0.9237 | 1.0643 | 0.9782 |
N(6)-Methyllysine | 0.7939 | 1.1241 | 1.0097 |
N-Acetylalanine | 1.0636 | 0.9647 | 0.9930 |
N-Acetylasparagine | 0.5164 | 1.3522 | 0.9389 |
N-Acetylaspartate | 0.9638 | 0.9785 | 1.0612 |
N-Acetylcysteine | 0.8797 | 1.3590 | 0.5966 |
N-Acetylglucosamine | 0.5511 | 1.1009 | 1.2541 |
N-Acetylglutamate | 1.0025 | 1.1030 | 0.8562 |
N-Acetylglycine | 0.7728 | 1.1470 | 0.9967 |
N-Acetylleucine | 0.3554 | 1.4470 | 0.9494 |
N-Acetyl-L-glutamine | 0.1928 | 1.5996 | 0.8818 |
N-Acetylmethionine | 0.7295 | 1.2651 | 0.8723 |
N-Acetylneuraminate | 0.3046 | 1.2549 | 1.2579 |
N-Acetylphenylalanine | 0.7863 | 1.0675 | 1.0941 |
N-Acetylputrescine | 0.6682 | 1.4328 | 0.6952 |
N-Acetylserine | 0.9691 | 0.9556 | 1.0881 |
N-Alpha-Acetyllysine | 0.4272 | 1.2527 | 1.1538 |
N-Amidino-L-Aspartate | 0.2302 | 1.2159 | 1.2805 |
Nervonic acid | 0.5708 | 1.3465 | 0.8991 |
N-Formyl-L-Methionine | 0.4826 | 1.3674 | 0.9476 |
Nicotinamide | 1.1214 | 0.9311 | 0.9885 |
Nicotinamide adenine dinucleotide phosphate (NADP+) | 0.7601 | 1.2840 | 0.8195 |
Nicotinamide adenine dinucleotide reduced (NADH) | 0.8072 | 1.1927 | 0.9038 |
N-Metyl-Alanine | 0.8555 | 0.9983 | 1.1287 |
Norvaline | 0.9166 | 0.9808 | 1.0994 |
Oleic acid | 1.1356 | 0.9543 | 0.9442 |
Omega-Hydroxydodecanoate | 0.8158 | 0.9810 | 1.1849 |
O-Phosphoethanolamine | 1.1033 | 0.9813 | 0.9354 |
O-Phosphoserine | 0.7509 | 1.3443 | 0.7445 |
Ophthalmate | 0.4263 | 1.4362 | 0.9023 |
Ornithine | 0.8786 | 1.0068 | 1.0969 |
Orotate | 1.0638 | 0.9470 | 1.0171 |
O-Succinyl-Homoserine | 0.4741 | 1.1429 | 1.2636 |
Oxoglutarate | 0.6225 | 1.0512 | 1.2599 |
Oxoproline | 0.7041 | 1.0239 | 1.2261 |
Palmitate | 0.9004 | 1.1262 | 0.9137 |
Palmitoleic acid | 1.0977 | 0.8936 | 1.0608 |
Pantothenate | 0.8426 | 1.0790 | 1.0291 |
Pentadecanoic acid | 1.0180 | 0.9092 | 1.1091 |
Pentanoate | 1.0841 | 0.9227 | 1.0326 |
Phenylalanine | 0.8940 | 1.0632 | 1.0058 |
Phenylpyruvate | 0.3384 | 0.6915 | 1.8818 |
Phosphocreatine | 0.4338 | 1.5640 | 0.7198 |
Phosphoenolpyruvate | 0.6305 | 1.2505 | 0.9789 |
Phosphorylcholine | 1.2749 | 0.8691 | 0.9395 |
Phosphoserine | 0.7509 | 1.3443 | 0.7445 |
Pipecolate | 0.8288 | 1.0416 | 1.0926 |
Proline | 0.8569 | 1.0190 | 1.0991 |
Propionyl-carnitine | 0.6079 | 1.2012 | 1.0665 |
Pterin | 1.2177 | 0.9791 | 0.8654 |
Pyridoxal | 0.9709 | 1.0098 | 1.0119 |
Pyrophosphomevalonate | 1.1478 | 1.0922 | 0.7439 |
Pyruvate | 1.1709 | 0.7978 | 1.1285 |
Pyruvate - IS | 1.0274 | 0.9871 | 0.9937 |
Quinolinate | 0.9323 | 1.0631 | 0.9726 |
Quinoline | 0.5671 | 1.4803 | 0.7184 |
Raffinose | 1.3458 | 0.9096 | 0.8216 |
Retinoate | 0.7254 | 1.0570 | 1.1619 |
Rhamnose | 1.0087 | 0.9420 | 1.0721 |
Riboflavin | 1.0101 | 1.1592 | 0.7723 |
Ribose | 0.8011 | 1.0374 | 1.1227 |
Ricinoleic acid | 0.9940 | 1.0053 | 0.9980 |
S-Adenosylhomocysteine | 1.0504 | 0.9443 | 1.0324 |
S-Adenosylmethionine | 0.8979 | 1.0583 | 1.0091 |
Sarcosine | 1.0263 | 0.9894 | 0.9915 |
Sedoheptulose-7-phosphate (D) | 0.9007 | 1.0056 | 1.0792 |
Serine | 0.9039 | 1.0265 | 1.0477 |
Serotonin | 1.2249 | 0.3917 | 1.6396 |
Sn-Glycero-3-Phosphocholine | 1.2293 | 0.9598 | 0.8547 |
Sphinganine | 0.9098 | 1.2908 | 0.6790 |
Sphingomyelin | 0.8112 | 1.1553 | 0.9516 |
Stachydrine (nv) | 1.0420 | 0.8119 | 1.2219 |
Stachyose | 1.4994 | 0.9016 | 0.6984 |
Stearic acid | 0.8616 | 1.1532 | 0.9104 |
Succinate | 0.9341 | 1.0201 | 1.0300 |
Succinyladenosine | 0.7142 | 1.0506 | 1.1806 |
Succinylaminoimidazole carboxamide riboside (SAICAr) | 1.1263 | 0.9473 | 0.9619 |
Succinylcysteine | 0.7766 | 1.0962 | 1.0631 |
Sucrose | 1.0390 | 0.9601 | 1.0207 |
Tartrate | 0.5616 | 1.1521 | 1.1744 |
Taurine | 1.0478 | 0.9923 | 0.9687 |
Thiamine Monophosphate | 1.0221 | 0.9730 | 1.0178 |
Thiamine Pyrophosphate | 0.7834 | 1.1749 | 0.9490 |
Threitol | 0.8264 | 1.0542 | 1.0774 |
Threonine | 0.8929 | 1.0689 | 0.9991 |
Thymidine | 0.7713 | 1.2050 | 0.9182 |
Thymidine-Monophosphate (TMP) | 1.6977 | 0.6148 | 0.9192 |
Thymine | 0.8973 | 1.0677 | 0.9968 |
Trans-4-Hydroxy-L-Proline | 0.6858 | 1.0882 | 1.1536 |
Trehalose | 1.0468 | 0.9688 | 1.0020 |
Tridecanoic acid | 1.0651 | 0.7824 | 1.2422 |
Trigonelline | 0.9543 | 1.0189 | 1.0140 |
Trimethyllysine | 0.9347 | 1.0059 | 1.0490 |
Tryptophan | 0.7967 | 1.2362 | 0.8531 |
Tyrosine | 0.8964 | 1.0333 | 1.0448 |
Undecanoic acid | 1.1998 | 0.7116 | 1.2217 |
Uracil | 1.1491 | 0.8214 | 1.1151 |
Urate | 0.8694 | 0.9779 | 1.1447 |
Ureidopropionate | 0.7191 | 1.0923 | 1.1189 |
Uridine | 0.9733 | 0.8958 | 1.1666 |
Uridine 5^-Diphosphate (UDP) | 0.9311 | 1.0742 | 0.9582 |
Uridine-5-triphosphate (UTP) | 0.8851 | 1.2440 | 0.7650 |
Uridine Diphosphategalactose | 1.2471 | 0.9419 | 0.8637 |
Uridine Diphosphate Glucose | 1.2471 | 0.9419 | 0.8637 |
Uridine Diphosphate Glucuronic Acid | 1.1329 | 1.0214 | 0.8543 |
Uridine Diphosphate-N-Acetylgalactosamine | 1.0906 | 0.9498 | 0.9898 |
Uridine Diphosphate-N-Acetylglucosamine | 1.0906 | 0.9498 | 0.9898 |
Uridine Monophosphate (UMP) | 1.4019 | 0.8273 | 0.8858 |
Urocanate | 0.5487 | 1.2707 | 1.0227 |
Valine | 0.9167 | 0.9807 | 1.0995 |
Xanthosine | 0.6865 | 1.2751 | 0.8960 |
Xanthosine-Monophosphate | 0.1834 | 0.8720 | 1.7884 |
Xanthurenate | 0.5657 | 1.6267 | 0.5183 |
Ximeninic Acid | 1.4086 | 0.8117 | 0.9014 |
Xylitol/Ribitol/Arabitol | 0.7985 | 1.1307 | 0.9966 |
Factors:
F1 | Genotype:Tsc1-knockout | Treatment:none |
F2 | Genotype:Tsc1-knockout | Treatment:rapamycin |
F3 | Genotype:Wild-type | Treatment:none |