Data for (Study ST002467)

(Analysis AN004023)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
1,3-bisphospho-D-glycerate 1.1040 0.8960
1-methylnicotinamide+ NA 1.0000
1-phenylethylamine 1.1947 0.8053
2,3-bisphospho-D-glycerate NA NA
2- / 3-phosphoglycerate 0.8901 1.1099
2-aminobutanoate / 2-aminoisobutanoate 1.5405 0.4595
2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine NA NA
2-HG 1.3407 0.6593
2-hydroxybutanoic acid 0.9322 1.0678
2-keto-isovaleric acid 0.8121 1.1879
2-ketovaleric acid NA NA
2-oxoadipic acid 1.0892 0.8662
2-oxobutanoic acid 0.5642 1.4358
3,4-dihydroxymandelic acid NA NA
3,4-dihydroxyphenylpropanoate 1.1784 0.7324
3- / 4 -hydroxybutanoic acid 0.8618 1.1382
3- / 4-hydroxyphenylacetic acid / vanillin / 1.1382 0.8618
3- / 7-methylguanine 1.5982 0.4018
3-aminoisobutanoate NA NA
3-hydroxy-anthranilic acid 1.1975 0.8025
3-hydroxykynurenine NA NA
3-hydroxypropanoic acid NA NA
3-methoxytyramine NA NA
3-phosphohydroxypyruvic acid 1.0000 NA
3-phospho-serine 0.8202 1.1798
3-ureidopropionic acid 0.3440 1.6560
4-hydroxyphenylpyruvic acid NA 1.0000
4-hydroxyproline / 5-aminolevulinate / N-acetyl-b-alanine 1.6881 0.3119
4-phosphopantothenate NA NA
4-trimethylammoniobutanoate+ 1.4154 0.5846
5,6-dihydroxyindole NA NA
5-HIAA 0.8099 1.1901
5-methylcytosine 1.1083 0.8917
5-methyl-THF NA NA
5^-methylthioadenosine 1.2364 0.7636
6-aminocaproic acid 1.1044 0.8956
6-methylnicotinamide 1.7287 0.2713
6-O-methylguanine NA NA
6-phosphogluconic acid 1.1254 0.8746
6-phosphoglucono-D-lactone NA NA
acetoacetic acid / succinic semialdehyde 1.1713 0.8287
acetylcholine+ 1.6178 0.3822
acetyl-CoA NA NA
aconitic acid 1.0698 0.9302
adenine 1.1290 0.8710
adenosine 0.8571 1.1429
adenylosuccinate 0.9879 1.0121
ADP / dGDP 0.7033 1.2967
ADP-D-glucose NA NA
agmatine 1.2511 0.2468
AICA ribonucleotide 0.2263 1.7737
a-KG 1.2136 0.7864
alanine 1.4379 0.5621
alanine methyl ester 1.2424 0.7576
allantoin 1.2016 0.7984
AMP / dGMP 1.5369 0.4631
anandamide NA NA
arginine 1.1018 0.8982
ascorbic acid 1.5441 0.4559
asparagine 1.0952 0.9048
aspartic acid 1.0690 0.9310
ATP / dGTP 0.2870 1.7130
b-alanine 1.5339 0.4661
betaine 1.0731 0.9269
butyric acid 0.7256 1.2744
butyric acid(iso) 1.2268 0.7732
carbamoyl phosphate 1.0281 0.9578
carnitine+ 1.3106 0.6894
CDP 0.8909 1.1091
CDP-choline 1.3852 0.6148
cGMP 0.8436 1.4691
choline+ 1.1023 0.8977
citraconic acid 1.0783 0.9217
citramalic acid 1.0253 0.9747
citrate / citrate(iso) 0.9943 1.0057
citrulline NA 1.0000
CMP 1.3464 0.6536
cortisol 1.1550 0.9225
creatine 1.2522 0.7478
creatinine 1.0807 0.9193
CTP 0.2142 1.7858
cystathionine 0.5540 1.4460
cysteine 1.1857 0.8143
cysteine-S-sulfate 0.8827 1.1173
cystine 1.0523 0.9477
cytidine 1.2688 0.7312
cytosine 0.9774 1.0226
dADP NA NA
dAMP NA NA
D-arabinono-1,4-lactone 1.6454 0.3546
dATP NA NA
dCDP 0.8962 1.3113
dCMP 1.1026 0.8974
dCTP 0.3683 1.6317
dehydroascorbic acid 1.2568 0.7432
deoxyguanosine NA NA
deoxyinosine 1.5723 0.4277
deoxyuridine 1.7511 0.2489
D-erythrose-4-phosphate 0.9547 1.0453
D-galactonic acid / D-gluconic acid 1.4867 0.5133
D-galactosamine/glucosamine-1/6-phosphate 0.3856 1.6144
dihydroorotate 1.3305 0.6695
dimethylglycine NA NA
DL-DOPA 1.0848 0.9152
DOPAC 0.8365 1.2453
dopamine NA NA
D-ribose-1/5-phosphate / D-ribulose 5-phosphate 1.2971 0.7029
D-sedoheptulose-7-phosphate 0.8644 1.1356
dTMP 1.0000 NA
dTTP NA NA
dUMP NA NA
dUTP NA NA
epinephrine 0.8521 1.1479
ethyl acetate 0.9115 1.0885
F-1,6/2,6-DP 0.6449 1.3551
F1P 0.7849 1.2151
F6P / G1P / G6P 0.5882 1.4118
FAD NA NA
FMN NA NA
folic acid NA NA
fructose / mannose 1.1044 0.8956
fumaric acid 1.3276 0.6724
GABA 0.6462 1.3538
galactosamine / glucosamine 1.1213 0.8787
galactose / glucose 0.9725 1.0275
GalNAC/GlcNAC/ManNAC 0.7734 1.2266
GAP / DHAP 0.6697 1.3303
GDP 0.6838 1.3162
GDP-L-fucose 1.1586 0.8414
glucono-lactone 1.1615 0.8385
glutaconic acid 1.2948 0.7052
glutamine 1.5047 0.4953
glutaminic acid 1.0288 0.9712
glutathione 1.3248 0.6752
glutathione disulfide 1.1379 0.8621
glyceraldehyde NA NA
glyceric acid 0.7012 1.2988
glycerol 2/3-phosphate 0.9348 1.0652
glycine 1.6539 0.3461
glycylglycine 1.0000 NA
GMP 1.3073 0.6927
GTP 0.2673 1.7327
guanidine 1.1392 0.8608
guanidinoacetate 1.8094 0.1906
guanine 1.7217 0.2783
guanosine 1.7244 0.2756
gulonic-lactone 0.9852 1.0148
histamine 0.3851 1.6149
histidine 1.4400 0.5600
homocysteine NA NA
homoserine / theronine 1.4369 0.5631
hydroxyphenyllactic acid / HVA 1.2485 0.7515
hypoxanthine 1.4813 0.5187
IDA 0.4722 1.5278
IDP 0.5333 1.4667
imidazole-4-acetate 1.1034 0.8966
IMP 1.0327 0.9673
inosine 1.6529 0.3471
isonictinic acid 1.3834 0.6166
itaconic acid 1.6621 0.3379
kynurenic acid 0.9458 1.1084
kynurenine 0.7622 1.2378
lactic acid 0.7003 1.2997
L-arginino-succinate 0.3036 1.6964
L-cysteic acid NA NA
leucine / leucine(iso) 1.3258 0.6742
levulinic acid NA NA
L-NMMA 1.5053 0.4947
L-tyrosine methyl ester NA NA
lysine 1.3330 0.6670
maleic acid NA NA
malic acid 1.4496 0.5504
malonyl-CoA NA NA
mesaconic acid 1.0000 NA
methionine 1.3549 0.6451
methyl acetoacetate 1.0456 0.9089
methylglyoxal 0.8888 1.1112
methylmalonic acid 1.2045 0.6932
mevalonic acid 0.6196 1.3804
N1/N8-acetylspermidine 1.1098 0.8902
N-acetylaspartic acid 1.0036 0.9964
N-acetylaspartylglutamic acid 0.9211 1.0789
N-acetyl-DL-alanine 1.1174 0.8826
N-acetyl-DL-serine 1.5502 0.4498
N-acetyl-dopamine 0.7689 1.2311
N-acetylglucosamine 1/6-phosphate 0.8348 1.1652
N-acetyl-L-glutamic acid 1.0000 NA
NAD+ 1.4409 0.5591
NADH NA NA
NADP+ 0.9679 1.0321
NADPH 0.9988 1.0012
N-carbamoyl-L-aspartate NA NA
nebularine 1.0943 0.9057
nicotinamide 1.1543 0.8457
nicotinamide riboside+ NA NA
nicotinic acid 1.2233 0.7767
N-methyltryptamine 1.0401 0.9399
NMN 1.0216 0.9784
norepinephrine 1.0138 0.9908
O-acetyl-L-serine 1.4583 0.5417
octopamine 1.0934 0.9066
ornithine 1.5413 0.4587
orotic acid 0.3392 1.6608
orotidylic acid NA 1.0000
oxalacetic acid 1.0000 NA
pantothenic acid 0.7086 1.2914
phenethylamine NA NA
phenylalanine 1.6082 0.3918
phenylephrine / synephrine 1.3132 0.6868
phosphocreatine 0.4105 1.5895
phosphoenolpyruvate 1.0772 0.9228
phosphorylcholine+ 1.4123 0.5877
picolinic acid 0.8202 1.1798
proline 1.0917 0.9083
propionic acid NA NA
PRPP 1.0000 NA
pseudouridine 1.0832 0.9168
putrescine 1.0640 0.9360
pyridoxine 0.7852 1.2148
pyroglutamic acid 0.6517 1.3483
pyrroline hydroxycarboxylic acid 1.3463 0.4805
pyruvic acid 0.7657 1.2343
quinolinic acid 1.5717 0.4283
(S)-4-hydroxymandelonitrile 0.6621 1.3379
S-adenosyl-L-homocysteine NA NA
S-adenosyl-L-methionine+ 1.1227 0.8773
S-adenosylmethioninamine+ NA NA
SAICAR 0.1963 1.2679
sarcosine 0.6991 1.3009
serine 1.2754 0.7246
serotonin NA 1.0000
sorbitol / galactitol / L-iditol / manitol 1.0019 0.9981
spermidine 1.4569 0.5431
spermine 1.2540 0.7460
succinic acid 1.1166 0.8834
succinyl-CoA 0.8918 1.3247
taurine 1.1176 0.8824
thiamine+ 0.7128 1.2872
thymidine 1.0696 0.9304
thymine 0.7008 1.2992
tryptamine 1.2575 0.7425
tryptophan 1.5274 0.4726
tyramine 1.1840 0.8160
tyrosine 1.3018 0.6982
UDP 0.8809 1.1191
UDP-D-glucose 1.0274 0.9726
UDP-N-acetyl-galactosamine/UDP-N-acetyl-glucosamine 1.2865 0.7135
UMP 1.3434 0.6566
uracil 1.1110 0.8890
urea 1.4262 0.5738
uric acid 0.8835 1.1165
uridine 1.5909 0.4091
UTP 0.3262 1.6738
valine 1.0390 0.9610
xanthine 1.4806 0.5194
xanthosine 0.8276 1.1724
xanthurenic acid NA NA
XMP 1.2283 0.7717
y-glutamylcysteine NA NA
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Factors:

F1Treatment:IR
F2Treatment:IR + LNP
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