Data for (Study ST002531)

(Analysis AN004165)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4
2-aminobutyrate 0.9072 0.9133 1.0679 1.0817
2-aminobutyrate-13C 1.0071 1.0020 1.0140 0.9769
2-hydroxybutyrate 0.1296 0.4664 3.4040 0.0000
2-hydroxybutyrate-13C4 NA NA NA NA
2-hydroxyglutarate 0.0422 0.1008 1.9140 1.9429
2-hydroxyglutarate-13C5 1.1513 1.0898 0.8922 0.8666
3-hydroxybutyrate 0.0034 0.0028 1.9907 1.8370
3-hydroxybutyrate-13C4 NA NA NA NA
3-hydroxyisobutyric-acid 0.0154 0.0150 1.4070 1.4135
3-hydroxyisobutyric_acid-13C4 0.1602 1.1280 1.3047 0.7619
3-methyl-2-oxobutyrate 0.0287 0.2635 1.9371 1.2850
3-methyl-2-oxobutyrate-13C5 0.9214 1.2110 0.9265 0.9411
3methyl2-oxopentanoic-acid 0.0272 2.1827 0.2561 1.5341
3methyl2-oxopentanoic-acid-13C 1.0625 1.0341 1.0509 0.8525
3-phosphoglycerate 0.0040 0.0435 1.6950 1.4275
3-phosphoglycerate-13C3 1.1674 1.0960 0.8793 0.8573
a-aminobutyrate 1.0992 3.0830 1.2230 0.0000
a-aminobutyrate-13C4 NA NA NA NA
acetylalanine 0.1150 0.2418 1.6630 1.6012
acetylalanine-13C5 0.9507 1.0829 0.9811 0.9853
acetylaspartate NA NA 0.6376 1.3624
acetylaspartate-13C6 NA NA NA NA
acetylcarnitine 0.0025 0.0039 2.0831 1.9105
acetylcarnitine-13C9 1.3387 1.4380 0.5589 0.5973
acetylglutamate NA 0.0394 1.3143 1.6463
acetylglutamate-13C7 0.9990 1.0096 0.9925 0.9989
acetylglutamine 0.1314 0.1708 1.8430 1.8547
acetylglutamine-13C7 0.9769 0.9784 1.0332 1.0114
acetylglycine 0.0904 0.1058 1.5031 1.3937
acetylglycine-13C4 NA NA NA NA
acetylmethionine NA 1.0000 NA NA
acetylmethionine-13C7 NA NA NA NA
ADP NA NA NA NA
ADP-13C10 1.5112 1.3250 0.6104 0.5533
AHB 0.0243 0.0897 1.7371 2.1489
AHB-13C4 NA NA NA NA
AKB 0.5348 0.5351 2.2801 0.6500
AKB-13C4 0.8061 1.2609 1.0693 0.7774
akg 0.0160 0.9811 1.1948 1.8081
akg-13C 1.2001 1.0587 0.9437 0.7974
alanine 0.0170 0.2780 1.8592 1.8458
alanine-13C3 1.6615 1.6801 0.3562 0.3022
allantoin 0.0098 0.0052 1.8629 1.9563
allantoin-13C4 NA NA NA NA
Aminoadipate 0.0270 0.1237 1.3007 1.2996
aminoadipate-13C6 1.1469 1.1603 0.8733 0.8195
AMP NA NA 1.0000 NA
AMP-13C10 1.0000 NA NA NA
arginine 2.2456 1.7357 0.0161 0.0026
arginine-13C6 0.5335 0.6467 1.4154 1.4044
argininosuccinate NA NA NA NA
argininosuccinate-13C10 0.9969 0.8151 1.5641 NA
ascorbate 0.3356 1.9912 0.2242 0.5377
ascorbate-13C 0.9851 1.1981 0.9673 0.8577
asparagine 1.5330 1.4984 0.4757 0.4929
asparagine-13C4 0.8885 1.0139 1.0231 1.0745
aspartate 0.6947 0.6928 1.3014 1.3111
aspartate-13C4 1.1210 1.1124 0.8817 0.8850
asymmetric-dimethylarginine 0.1194 2.0608 0.2013 1.6184
asymmetric-dimethylarginine٨_1 0.9596 0.9881 1.0637 0.9991
ATP NA NA NA NA
ATP-13C10 0.9871 1.0215 NA NA
beta-Alanine 0.0244 0.0345 1.7691 1.8502
beta-alanine-13C3 0.9478 1.0876 0.9804 0.9842
betaine 0.0196 0.0256 3.9548 0.0000
betaine-13C5 1.0047 0.9953 NA NA
biotin 1.9852 1.8910 0.1237 0.0000
biotin-13C10 NA NA NA NA
Carbamoylaspartate 0.0148 0.5451 1.6885 1.7515
carbamoylaspartate-13C5 1.4067 1.3265 0.6069 0.6599
carnitine 0.0011 0.0018 1.9582 2.0389
carnitine-13C7 0.9693 0.9728 1.0577 1.0002
carnosine 0.0668 0.1492 2.4391 0.0000
carnosine-13C9 NA NA NA NA
CDP NA NA NA NA
CDP-13C9 NA NA NA NA
CDP-choline NA NA NA NA
CDP-choline-13C14 NA NA NA NA
choline 0.6473 0.4749 2.8778 0.0000
choline-D9 0.9643 0.9533 1.2472 NA
cis-aconitic-acid 0.0085 0.1737 1.7078 2.1099
cis-aconitic-acid-13C6 1.1391 1.1045 0.8917 0.8647
citrate 0.0279 0.2921 1.8916 1.7885
citrate-13C6 1.7112 1.2685 0.5300 0.4903
citrulline 0.0158 0.0207 2.0001 1.9635
Citrulline-13C 1.1813 1.1905 0.8027 0.8255
citrulline-13C6 1.1813 1.1905 0.8027 0.8255
CMP NA NA 1.0000 NA
CMP-13C9 1.0892 0.9108 NA NA
CoA NA NA NA NA
CoA-13C21 NA NA NA NA
creatine 0.0510 0.0179 3.9311 0.0000
creatine-13C4 NA NA NA NA
creatinine 0.0172 0.0092 1.8651 2.1085
creatinine-D3 1.0053 0.9973 1.0150 0.9823
CTP NA NA NA NA
CTP-13C9 NA NA NA NA
cys-gly 1.0210 0.8099 1.1755 0.9936
cys-gly-13C5 1.2148 0.4741 1.2634 0.9160
Cystathionine NA NA NA NA
cystathionine-13C7 0.8571 0.9729 1.1346 1.0354
Cysteic-acid NA 0.9128 1.0872 NA
cysteic-acid-13C3 NA NA NA NA
cystine 1.1934 2.2466 0.3011 0.2588
cystine-13C2 0.4674 1.0852 1.2812 1.1663
cystine-13C6-15N2 0.4674 1.0852 1.2812 1.1663
cystine-13C615N2 0.4674 1.0852 1.2812 1.1663
cytidine 0.0457 0.1324 3.8219 0.0000
cytidine-13C9 1.0502 0.8577 1.3184 NA
dATP NA NA NA NA
dATP-13C10 NA NA NA NA
dCTP NA NA NA NA
dCTP-13C9 NA NA NA NA
deoxycytidine 0.0027 1.2383 1.6128 0.8137
deoxycytidine-13C9 NA NA NA NA
DHAP 0.0271 0.0267 1.9833 0.6654
DHAP-13C3 1.0000 NA NA NA
dimethylglycine 1.0485 0.7235 1.2067 0.9753
dTMP NA NA NA NA
dTMP-13C10 NA NA NA NA
FAD NA NA NA NA
FAD-13C27 NA NA NA NA
folate 1.0059 0.9941 NA NA
folate-13C19 NA NA NA NA
formyl-methionine 0.1544 0.2568 2.3596 1.2292
formyl-methionine-13C6 NA NA NA NA
Fructose 1.6188 2.2710 0.2134 0.0000
Fructose-13C6 NA NA NA NA
Fructose-1-6-bisphosphate NA NA NA NA
fructose-1,6-bisphosphate-13C6 NA NA NA NA
Fumarate 0.4841 0.4802 1.5384 1.4974
fumarate-13C4 NA NA NA NA
gaba 0.1252 0.2051 1.8301 1.6938
gaba-13C4 1.0299 1.0922 0.9619 0.9160
gamma-glutamyl-alanine NA NA 0.3277 1.6723
gamma-glutamyl-alanine-13C8 0.6315 0.6651 1.3202 1.3832
GDP NA NA NA NA
GDP-13C10 NA NA NA NA
Glucose 1.8232 1.2796 0.6716 0.2256
glucose-13C6 0.9921 1.0275 0.9939 0.9865
glucose-1-phosphate NA 0.2312 2.3844 0.0000
glucose-1-phosphate-13C6 NA NA NA NA
Glucose-6-phosphate 0.0170 0.0045 1.7058 1.4536
glucose-6-phosphate-13C6 1.1975 1.1883 0.7956 0.8186
glutamate 0.3070 0.4641 1.5023 1.7265
glutamate-13C 1.2375 0.8531 NA 0.3094
glutamate-13C5 1.0910 1.0062 0.7086 NA
glutamine 1.6064 1.1071 0.7268 0.5597
glutamine-13C5 0.8586 1.0600 1.0049 1.0766
glycerate 0.1196 0.2036 1.5358 2.1410
glycerate-13C3 NA 0.9755 1.1613 0.8878
Glycerol-3-phosphate NA NA NA NA
glycerol-3-phosphate-13C3 NA NA NA NA
Glycerophosphocholine 0.0323 0.0993 2.0197 1.8487
glycerophosphocholine-13C8 1.7747 1.6017 0.3414 0.2823
glycine 0.1324 0.1250 1.8385 1.9041
glycine-13C2 1.1148 1.1577 0.8712 0.8562
gly-gly 1.5239 1.4931 0.4832 0.4998
gly-gly-13C 0.9368 1.0861 0.9594 1.0178
GMP NA NA 1.0000 NA
GMP-13C10 NA NA NA NA
gsh 1.1908 0.6508 1.0264 NA
gsh-13C10 1.0461 1.0405 0.7403 NA
gssg NA NA 1.0501 0.9499
gssg-13C20 0.6595 0.9609 1.2233 1.1563
GTP NA NA NA NA
GTP-13C10 NA NA NA NA
Guanidinoacetate 0.0017 0.0139 1.5289 1.6235
guanidinoacetate-13C3 NA NA NA NA
histidine 1.3136 1.1414 0.7854 0.7596
histidine-13C6 1.0631 1.0932 0.5311 NA
homocitrulline NA NA 1.0042 0.9958
homocitrulline-13C7 NA NA NA NA
homocysteine 1.4617 1.0901 0.7503 0.6980
homocysteine-13C4 NA NA NA NA
hydroxyproline 1.0154 0.9846 NA NA
hydroxyproline-13C5 NA NA NA NA
hypotaurine NA NA 0.9836 1.0164
hypotaurine-13C2 NA NA NA NA
hypoxanthine 0.0053 0.0058 1.8095 2.1794
hypoxanthine-13C5 1.2287 1.1253 0.8666 0.7794
IMP NA 0.7340 1.1330 NA
IMP-13C10 NA NA NA NA
indolelactate 0.5885 0.6272 1.3546 1.4297
indolelactate-13C11 1.0860 1.3049 0.3837 1.2253
Inosine 0.0044 0.0092 1.9608 1.0308
inosine-13C10 0.9444 1.0556 NA NA
isoleucine 1.5631 1.2665 0.6114 0.5590
isoleucine-13C 1.0320 1.0023 0.9770 0.9887
isoleucine-13C6 1.0320 1.0023 0.9770 0.9887
itaconate-13C 1.3527 1.2496 0.6470 0.6919
itaconic-acid 0.0116 0.0789 1.7865 1.9583
Kynurenine 0.4261 0.4021 1.6328 1.5391
kynurenine-13C10 1.2226 1.0871 0.8719 0.8183
lactate 0.0049 1.2735 0.7872 1.9343
lactate-13C3 0.9661 1.0058 1.0631 0.9650
L-Alpha-aminobutyric-acid-13C4 1.0053 0.9981 1.0132 0.9834
L-Alpha-aminobutyric-acid-2ߕ_4 0.7225 0.6824 1.3018 1.2933
leucine 1.2618 0.9119 0.9751 0.8513
leucine-13C6 1.0388 1.0004 1.0023 0.9585
lysine 1.2832 0.9090 0.9260 0.8817
lysine-13C6 0.9515 0.9595 1.0550 1.0340
Malate 0.0174 0.0981 1.9638 1.9207
malate-13C4 1.1224 1.0962 0.9121 0.8694
mannose 1.1943 0.8173 NA 0.5882
mannose-13C6 0.4207 0.9432 1.9092 0.7836
methionine 1.1735 0.9323 0.9556 0.9385
methionine-13C5 0.9615 1.0342 0.9918 1.0124
methionine-sulfoxide 0.7710 0.7795 1.2173 1.2322
Methionine_sulfoxide-13C 0.9634 0.9594 1.0441 1.0330
methionine-sulfoxide-13C5 0.9590 0.9574 1.0460 1.0376
methylthioadenosine NA 1.0361 1.4635 0.4281
methylthioadenosine-13C11 1.0731 1.0505 0.9514 0.9250
myo-inositol 0.6296 0.5775 1.4240 1.3689
myo-inositol-13C6 1.0000 NA NA NA
N6-acetyllysine 0.0840 0.1187 1.9186 1.8787
N6-acetyllysine-13C8 0.9948 0.9477 1.0654 0.9921
NAD NA NA NA NA
NAD-13C21 1.2043 1.1494 0.8320 0.8142
NADP NA NA NA NA
NADP-13C21 0.8880 NA NA 1.0560
Niacinamide 0.3871 0.3544 1.5978 1.6607
niacinamide-13C6 1.0808 1.0408 0.9339 0.9445
o-phosphoethanolamine 0.1308 NA 2.1449 0.0000
o-phosphoethanolamine-13C2 NA NA NA NA
ornithine 0.4995 1.2572 1.1180 1.1253
ornithine-13C5 1.3832 0.8035 0.9179 0.8954
Orotate 0.0052 0.2494 1.8441 1.9013
orotate-13C5 0.9956 0.9834 1.0257 0.9953
Oxoglutarate NA NA NA NA
oxoglutarate-13C5 1.1659 1.0531 0.9679 0.8131
p-aminobenzoate 1.0216 0.4605 1.3036 0.6070
p-aminobenzoate-13C7 NA NA NA NA
Pantothenate 0.5633 0.5083 1.4631 1.4652
pantothentate-13C9 1.0333 1.0064 1.0020 0.9583
phenylacetylglutamine 0.4226 0.4313 2.4305 NA
phenylacetylglutamine-13C13 NA NA NA NA
phenylalanine 1.0983 0.7693 1.0661 1.0663
phenylalanine-13C9 0.9090 0.9268 1.0757 1.0885
phosphocholine 0.0017 0.0248 2.2948 1.6787
phosphocholine-13C5 1.0194 1.0166 0.9643 0.9996
phosphocreatine NA NA 1.2791 0.7209
phosphocreatine-13C4 NA NA NA NA
Phosphoenolpyruvate 0.0006 0.0361 2.0361 1.4275
phosphoenolpyruvate-13C3 1.2480 1.1436 0.7495 0.8590
Phosphoserine NA NA NA NA
phosphoserine-13C3 NA NA NA NA
picolinate NA NA NA NA
picolinate-13C6 NA NA NA NA
pipecolate 0.0111 0.8965 1.5250 1.5673
pipecolate-13C6 0.9680 0.9523 1.0402 1.0396
proline 1.1015 1.1266 0.8465 0.9254
proline-13C 0.9691 0.9601 1.0515 1.0193
proline-13C5 0.9691 0.9601 1.0515 1.0193
pyridoxal 0.2883 3.6725 0.0392 0.0000
pyridoxal-13C8 1.2521 0.8132 0.8040 NA
pyridoxine 2.0501 1.8568 0.0530 0.0400
pyridoxine-13C8 1.4794 0.6889 0.8520 1.1052
pyroglutamate-5-oxoproline 0.6028 2.0564 0.3443 0.9964
pyroglutamate-5-oxoproline-13C5 0.9994 0.8990 1.0971 1.0045
pyruvate 0.0139 2.9278 0.3926 0.6656
pyruvate-13C3 0.9966 0.9960 1.0448 0.9627
Riboflavin 1.5129 1.4605 0.0281 0.0237
riboflavin-13C17 NA NA NA NA
ribose-5-phosphate 0.0007 0.0037 2.4334 0.7295
ribose-5-phosphate-13C5 1.2091 0.7737 0.5990 NA
sah NA 0.0399 1.5044 1.4558
SAH-13C14 0.9974 0.9757 1.0262 1.0007
sarcosine 0.0725 0.0520 1.8414 1.8795
sarcosine-13C3 NA NA NA NA
serine 1.3588 0.8388 0.9363 0.8660
serine-13C3 1.0102 1.0190 1.0032 0.9676
sorbitol 0.3155 0.4360 1.4488 1.5717
sorbitol-13C6 1.0276 0.8967 1.0977 0.9736
Succinate 0.0401 0.0650 1.8943 2.0005
succinate-13C4 0.9864 0.9821 1.0310 1.0006
taurine 0.0015 0.0033 1.4158 1.4157
taurine-13C2-15N 1.2935 1.2826 0.7285 0.6954
thiamine NA NA NA NA
thiamine-13C12 NA NA NA NA
threonine 1.0716 0.7809 1.1219 1.0256
Threonine-13C 1.1264 0.9827 0.6727 NA
threonine-13C4 1.2176 1.1837 0.8423 0.7563
thymidine 0.1650 0.0188 1.5650 1.5554
thymidine-13C10 NA NA NA NA
trans-urocanate 1.2620 1.8421 0.8959 0.0000
trans-urocanate-13C6 NA NA NA NA
trimethyllysine 0.6132 1.2567 0.7837 1.3465
trimethyllysine-13C9 0.9481 1.0048 1.0613 0.9858
tryptophan 0.9550 0.7312 1.1496 1.1642
tryptophan-13C11 1.0331 1.1416 0.8510 0.9743
tyrosine 1.3399 1.0196 0.8366 0.8040
tyrosine-13C9 1.1114 0.9443 0.9840 0.9603
UDP NA NA 1.0000 NA
UDP-13C9 NA NA 1.0248 0.9752
UDP-GlcNAc NA NA 1.0000 NA
UDP-GlcNAc-13C17 1.0168 1.0123 0.9933 0.9777
UDP-glucose NA NA 1.0000 NA
UDP-glucose-13C15 1.0653 1.0369 0.9917 0.9061
UMP NA NA 1.0000 NA
UMP-13C9 NA NA NA NA
Uracil 0.0053 0.0060 1.6979 2.2909
uracil-13C NA NA NA NA
uracil-13C4 1.0264 1.0099 1.0226 0.9411
Uric-acid 0.1415 0.1892 1.3421 2.3272
uric-acid-13C5 1.0000 NA NA NA
uridine 0.0431 0.0036 1.2866 1.9170
uridine-13C9 NA NA 0.8894 1.0553
UTP NA NA NA NA
UTP-13C9 NA NA NA NA
valine 0.8097 1.6695 0.7641 0.7568
valine-13C 0.9539 0.9487 1.0632 1.0342
valine-13C5 0.9539 0.9487 1.0632 1.0342
xanthine 0.0107 0.1680 3.6564 0.0000
xanthine-13C5 NA NA NA NA
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Factors:

F1Media:RPMI | Collection_Time:Day_1
F2Media:RPMI | Collection_Time:Day_2
F3Media:TIFM | Collection_Time:Day_1
F4Media:TIFM | Collection_Time:Day_2
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