Data for (Study ST002729)
(Analysis AN004423)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 1,5-Anhydro-D-glucitol | 0.4422 | 0.3472 | 0.0374 | 2.4488 |
| 1,6-Anhydro-beta-D-glucose | 1.1992 | 2.3785 | 0.0550 | 0.5782 |
| 2,3-Bisphosphoglycerate | 1.0637 | 1.4515 | 0.5542 | 0.9538 |
| 2,3-Pyridinedicarboxylic acid | 0.7759 | 1.1123 | NA | 1.1118 |
| 2^-Deoxycytidine 5^-monophosphate | NA | NA | NA | NA |
| 2-deoxyribose 5-phosphate | NA | NA | NA | NA |
| 2^-Deoxyuridine 5^-phosphate | NA | NA | NA | NA |
| 2-Ethylhexanoic acid | 1.0596 | 1.2982 | NA | 0.6422 |
| 2-Hydroxy-3-methylbutyric acid | 1.0289 | 1.7711 | 0.0659 | 1.0894 |
| 2-Hydroxy glutaric acid | 0.6700 | 1.2542 | 1.0520 | 1.0158 |
| 2-Ketoadipic acid | 0.8888 | 1.2966 | NA | 0.8145 |
| 2-Ketoglutaric acid | 1.3868 | 1.6329 | 0.3052 | 0.7834 |
| 2-Phospho-D-glyceric acid | 0.8858 | 0.8016 | 1.3432 | 0.9796 |
| 3-Hydroxy-3-methylglutaric acid | 1.4837 | 1.3177 | 0.1446 | 1.0360 |
| 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5^-monophosphate | NA | 1.4720 | 0.7086 | 0.9767 |
| 6-Phosphogluconic acid | 1.1979 | 0.9098 | 0.9521 | 0.9940 |
| Acetylglycine | 1.7460 | 0.8663 | 0.0694 | 1.2122 |
| Adenosine 3^,5^-cyclic monophosphate | 0.7996 | 1.0811 | 1.1406 | 0.9191 |
| Adenosine 5^-diphosphate | 1.5627 | 0.9735 | 1.1521 | 0.7199 |
| Adenosine 5^-diphosphate ribose | 0.8238 | 0.8258 | 0.8364 | 1.3388 |
| Adenosine 5^-monophosphate | 1.1741 | 1.0048 | 0.9028 | 1.0078 |
| Adenosine 5^-triphosphate | 1.4422 | 0.8381 | 1.1687 | 0.7941 |
| Adenylosuccinic acid | 0.8798 | 0.8720 | 0.5847 | 1.5394 |
| Allantoic acid | 1.1308 | 1.1690 | 0.1085 | 1.3944 |
| Allantoin | 1.3614 | 1.1858 | 0.0670 | 1.2571 |
| Alpha-Ketovaline | 1.1975 | 1.5407 | 0.0605 | 1.2013 |
| Azelaic acid | 0.9506 | 1.1045 | 0.8060 | 1.0926 |
| Beta-Lactose | 0.8511 | 1.9552 | 0.6100 | 0.7224 |
| Caproic acid | 1.1885 | 1.5224 | 0.5493 | 0.8266 |
| cis-Aconitic acid | 1.2599 | 1.3157 | 0.1843 | 1.1601 |
| Citric acid | 1.2921 | 1.3904 | 0.2315 | 1.0573 |
| Coenzyme A | 0.7309 | 0.8017 | 1.0438 | 1.1899 |
| Creatine phosphate | 0.8320 | 0.4512 | 1.3862 | 1.2204 |
| Cytidine 5^-diphosphate | 0.8449 | 1.2857 | 0.9928 | 0.9419 |
| Cytidine-5^-monophosphate | 0.7623 | 1.2461 | 0.7668 | 1.2291 |
| Cytidine 5^-triphosphate | 1.1089 | 0.8567 | 1.0401 | 0.9771 |
| D-Arabitol | 1.3105 | 1.5472 | 0.3689 | 0.8489 |
| Deoxyadenosine 5^-triphosphate | 0.9363 | 0.7773 | 0.9662 | 1.2319 |
| Deoxycytidine 5^-triphosphate | 0.8064 | 0.8060 | 1.0992 | 1.0954 |
| Deoxythymidine 5^-diphosphate | 0.6814 | 0.9897 | NA | 1.2467 |
| Deoxythymidine 5^-monophosphate | NA | NA | NA | NA |
| Deoxythymidine 5^-triphosphate | 1.2589 | 0.9122 | 0.8766 | 1.0299 |
| D-Fructose 1,6-bisphosphate | 1.2788 | 0.9575 | 1.1319 | 0.8182 |
| D-Fructose 1-phosphate | 0.9510 | 1.3429 | 1.2291 | 0.6240 |
| D-Fructose 6-phosphate | 0.3165 | 0.7092 | 1.7025 | 1.1242 |
| D-Galactosamine | 1.2050 | 2.3088 | 0.0705 | 0.6105 |
| D-Galactose 1-phosphate | 0.8855 | 1.3573 | 1.1552 | 0.8197 |
| D-Glucaric acid | 1.2663 | 1.4196 | 0.4717 | 0.8950 |
| D-Gluconic acid | 1.0817 | 2.0294 | 0.1101 | 0.8526 |
| D-Glucose 1-phosphate | 0.5611 | 0.9068 | 1.0523 | 1.2138 |
| D-Glucose 6-phosphate | 0.2825 | 0.5255 | 1.7004 | 1.3278 |
| D-Glucuronic acid | 1.0800 | 1.7396 | 0.0358 | 1.0964 |
| DL-4-Hydroxyphenyllactic acid | 0.9312 | 1.6743 | 0.3311 | 1.0423 |
| DL-Beta-Phenyllactic acid | 0.5404 | 1.8252 | NA | 0.6343 |
| D-Mannose 6-phosphate | 0.4908 | 0.5472 | 1.7760 | 1.1240 |
| D-Sedoheputulose 7-phosphate | 0.5952 | 1.5143 | 1.0753 | 0.8699 |
| D-Sorbitol 6-phosphate | 0.7165 | 1.6280 | 0.9351 | 0.8926 |
| Flavin adenine dinucleotide | 0.6354 | 1.2154 | 1.0197 | 1.0549 |
| Fumaric acid | 0.8375 | 1.3362 | 1.1635 | 0.7752 |
| Galactitol | 0.6257 | 2.3716 | 0.4766 | 0.6841 |
| GDP-D-mannose | 0.9116 | 1.0618 | 1.0213 | 0.9920 |
| Glycerol | 1.3890 | 1.3565 | 0.5612 | 0.7955 |
| Glycerol 3-phosphate | 0.8408 | 0.7890 | 1.3946 | 0.9838 |
| Guanosine 5^-diphosphate | 0.7097 | 1.3382 | 0.9568 | 1.0193 |
| Guanosine 5^-monophosphate | 0.5624 | 1.4070 | 0.7847 | 1.2050 |
| Guanosine 5^-triphosphate | 1.0575 | 0.9575 | 1.0317 | 0.9608 |
| Hexose | 1.1887 | 2.3794 | 0.0530 | 0.5859 |
| Hippuric acid | 1.0504 | 1.7022 | 0.0957 | 1.1012 |
| Hydrocinnamate | 1.1206 | 1.4286 | NA | 0.4508 |
| Hydroxybutyric acid (2-Hydroxybutyric acid, 3-Hydroxybutyric acid, 2-Hydroxyisobutyric acid, 3-Hydroxyisobutyric acid) | 2.7341 | 0.9194 | 0.0542 | 0.5282 |
| Hypoxanthine | 0.8435 | 1.0012 | 0.9908 | 1.0868 |
| Inosine 5^-diphosphate | 0.6717 | 0.9291 | 1.2259 | 0.9650 |
| Inosine 5^-monophosphate | 0.9608 | 1.1853 | 1.1686 | 0.8389 |
| Inosine 5^-triphosphate | 0.3012 | NA | 1.3659 | 0.9003 |
| Isocitric acid | 1.2255 | 1.3328 | 0.1912 | 1.1670 |
| Ketoisoleucine | 1.2931 | 1.6717 | 0.0442 | 0.9928 |
| Ketoleucine | 1.2864 | 1.9057 | 0.0527 | 0.8042 |
| Lactic acid | 1.1392 | 1.6504 | 0.4445 | 0.8439 |
| Lactitol | 0.5866 | 0.5394 | 0.5663 | 1.7340 |
| L-Cysteic acid | 0.8278 | 1.5089 | 0.4245 | 1.1592 |
| Leucinic acid | 1.2911 | 1.5222 | 0.0597 | 1.0847 |
| L-Homocysteic acid | 1.0178 | 0.8923 | 1.0983 | 1.0004 |
| L-Pyroglutamic acid | 0.9351 | 1.3546 | 0.7003 | 1.0066 |
| L-Threonic acid | 1.1492 | 1.5215 | 0.5213 | 0.8720 |
| Maleic acid | 1.4960 | 1.3582 | 0.3250 | 0.8805 |
| Malic acid | 0.9517 | 1.2711 | 0.9629 | 0.8762 |
| Maltotetraose | 0.4322 | 1.6176 | 0.9755 | 0.9996 |
| Na-Acetyl-L-asparagine | 1.3251 | 1.3779 | 0.1070 | 1.1266 |
| N-Acetyl-D-galactosamine | NA | NA | NA | NA |
| N-Acetyl-D-glucosamine 1-phosphate | 0.7297 | 1.2373 | 1.0788 | 0.9695 |
| N-Acetyl-D-glucosamine 6-phosphate | 1.0063 | 1.2759 | 0.9011 | 0.9180 |
| N-Acetyl-DL-alanine | 1.3048 | 1.4535 | 0.2436 | 0.9987 |
| N-Acetyl-L-aspartic acid | 1.1060 | 0.7052 | 1.0913 | 1.0650 |
| N-Acetyl-L-glutamate | 1.1617 | 1.8558 | 0.1574 | 0.8834 |
| N-Acetyl-L-glutamine | 1.0657 | 1.4201 | 0.0689 | 1.2969 |
| N-Acetyl-L-leucine | 0.7538 | 1.7212 | NA | 0.5250 |
| N-Carbamoyl-L-aspartate | 1.3373 | 1.5013 | 0.4129 | 0.8260 |
| Nicotinamide adenine dinucleotide | 1.0479 | 0.8302 | 1.0474 | 1.0136 |
| O-Acetyl-L-homoserine | 1.3731 | 1.3832 | 0.2158 | 1.0186 |
| O-Acetyl-L-serine | 1.1575 | 1.4754 | 0.2929 | 1.0494 |
| O-Phospho-L-serine | 0.6920 | 1.2716 | 1.1027 | 0.9155 |
| Orotic acid | 0.8554 | 1.7947 | 0.0526 | 1.1982 |
| Pantothenate | 0.5498 | 1.4191 | 1.0250 | 1.0040 |
| Pentose | 1.2015 | 2.2167 | 0.0591 | 0.6818 |
| Pentose monophosphate | 1.0621 | 0.8898 | 1.3713 | 0.7806 |
| Phosphoenolpyruvic acid | 1.4940 | 0.5379 | 0.8895 | 1.0945 |
| Phosphoribosyl pyrophosphate | 1.6600 | 0.3247 | 0.9410 | 1.0666 |
| Phosphoric acid | 1.2953 | 1.2765 | 0.6496 | 0.8524 |
| Pyridoxal 5^-phosphate | 1.0437 | 1.0840 | 1.0036 | 0.9045 |
| Pyrophosphate | 1.2894 | 1.2441 | 0.6912 | 0.8502 |
| Pyruvic acid | 0.8276 | 1.7287 | 0.1648 | 1.1860 |
| S-Sulfo-L-cysteine | 0.6428 | 1.2170 | NA | 1.1402 |
| Suberic acid | 1.2934 | 1.3457 | 0.5271 | 0.8892 |
| Succinic acid | 1.2149 | 1.3082 | 0.7759 | 0.8007 |
| Tartaric acid | 0.9213 | 1.3531 | 0.9175 | 0.8722 |
| Taurine | 0.8395 | 0.9021 | 1.2605 | 0.9986 |
| Thiamine pyrophosphate | 0.7392 | 1.1986 | 0.9288 | 1.1023 |
| Thymidine | 0.7217 | 1.3780 | NA | 0.9335 |
| UDP-alpha-D-galactose | 0.9483 | 0.9809 | 0.9096 | 1.1259 |
| UDP-N-acetyl-alpha-D-glucosamine | 0.8332 | 1.2053 | 0.9887 | 0.9920 |
| Uric acid | 1.3342 | 1.6961 | 0.0280 | 0.9611 |
| Uridine | 1.0351 | 1.3336 | 0.6475 | 0.9892 |
| Uridine 5^-diphosphate | 0.7772 | 1.3761 | 1.0066 | 0.9168 |
| Uridine 5^-diphosphate glucose | 0.8980 | 1.1282 | 0.9502 | 1.0368 |
| Uridine 5’-diphosphate (UDP)-D-glucuronate | 0.9272 | 1.2184 | 0.9754 | 0.9519 |
| Uridine 5^-monophosphate | 0.6753 | 1.2656 | 0.8397 | 1.1898 |
| Uridine 5^-triphosphate | 1.0687 | 0.9556 | 1.0620 | 0.9258 |
Factors:
| F1 | Animal:db/db | Treatment:Cana |
| F2 | Animal:db/db | Treatment:vehicle |
| F3 | Animal:db/+ | Treatment:Cana |
| F4 | Animal:db/+ | Treatment:vehicle |
