Data for (Study ST002729)
(Analysis AN004424)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 1-Methylhistidine | 1.1142 | 1.1650 | 0.2731 | 1.2985 |
| 3-Cyano-L-alanine | 0.7162 | 1.4840 | 1.0378 | 0.9081 |
| 4-Guanidinobutanoate | 0.3481 | 1.6859 | 1.1741 | 0.7751 |
| 4-Hydroxy-L-proline | 1.1880 | 0.6681 | 0.8321 | 1.2079 |
| 5^-Methylthioadenosine | 0.9210 | 0.7977 | 1.2130 | 1.0456 |
| Acetylglycine | 1.9764 | 0.8915 | 0.0748 | 1.0382 |
| Adenine | 1.2898 | 0.7388 | 0.9069 | 1.0700 |
| Adenosine | 0.3586 | 0.9491 | 1.4696 | 1.1484 |
| Adenylosuccinic acid | 1.0821 | 0.9594 | 0.6588 | 1.3205 |
| Allantoin | 1.5202 | 0.9948 | 0.3993 | 1.0571 |
| Amino adipic acid | 1.2351 | 1.2754 | 0.4362 | 1.0355 |
| Beta-Alanine | 0.9202 | 0.7024 | 1.3381 | 1.0263 |
| Beta-glutamic acid | 0.3559 | 1.3775 | 1.3536 | 0.9420 |
| Betaine | 1.6673 | 1.5258 | 0.2160 | 0.7273 |
| Carnitine | 0.6169 | 1.2643 | 1.0492 | 1.0464 |
| Carnosine | 2.1942 | 0.3115 | 0.9628 | 0.6877 |
| Choline | 1.0771 | 1.3369 | 0.8587 | 0.8182 |
| Creatine | 0.8784 | 0.6709 | 1.4206 | 1.0200 |
| Creatinine | 0.9632 | 0.8833 | 0.6753 | 1.3188 |
| Cytidine | 1.5492 | 1.2007 | 0.4315 | 0.8790 |
| Cytosine | 1.0199 | 1.1592 | 0.8698 | 0.9690 |
| Dimethylglycine | 1.2999 | 1.2500 | 0.4019 | 1.0321 |
| DL-2-Hydroxybutyric acid | 3.1849 | 0.7138 | 0.0637 | 0.3584 |
| Ethanolamine | 1.1772 | 1.2290 | 0.5860 | 1.0052 |
| Glycerol | 0.8945 | 1.0474 | 1.0240 | 1.0051 |
| Glycerophosphocholine | 0.6909 | 1.2872 | 1.3036 | 0.8122 |
| Glycine | 1.1439 | 1.0950 | 0.7027 | 1.0389 |
| Glycolic acid | 0.5313 | 1.8436 | NA | 0.6251 |
| Glycylglycine | 0.8283 | 0.9308 | 1.3128 | 0.9521 |
| Guanine | 0.4756 | 1.0860 | 1.4557 | 0.7635 |
| Guanosine | 0.1406 | 0.3874 | 0.3801 | 2.0847 |
| Histamine | 0.7818 | 0.9327 | 1.2015 | 1.0140 |
| Hydroxybutyric acid (3-Hydroxybutyric acid, 2-Hydroxyisobutyric acid) | 2.0047 | 1.4626 | 0.0748 | 0.6386 |
| Hypotaurine | 0.5330 | 0.9490 | 1.3629 | 1.1034 |
| Hypoxanthine | 0.5391 | 1.3219 | 0.8737 | 1.1740 |
| Imidazole lactate | 0.7844 | 1.0906 | 0.5586 | 1.3416 |
| Indoxyl sulfate | 1.2369 | 1.8948 | 0.0072 | 0.9074 |
| Inosine | 0.4927 | 1.1188 | 0.8966 | 1.2888 |
| L-Alanine | 0.6553 | 1.0150 | 1.2358 | 1.0626 |
| L-Arginine | 1.1172 | 1.5545 | 0.4684 | 0.9065 |
| L-Argininosuccinate | 0.4268 | 1.4349 | 1.0848 | 1.0357 |
| L-Asparagine | 0.8706 | 1.2027 | 0.5106 | 1.2774 |
| L-Asparate | 0.4285 | 0.9150 | 1.2233 | 1.2889 |
| L-Citrulline | 1.2404 | 1.3353 | 0.6377 | 0.8577 |
| L-Cysteine | NA | NA | NA | NA |
| L-Cystine | 0.5416 | 1.0743 | NA | 1.3841 |
| L-Glutamic acid | 0.3068 | 1.3680 | 1.3834 | 0.9612 |
| L-Glutamine | 0.5884 | 1.0457 | 1.2465 | 1.0796 |
| L-Histidine | 1.0509 | 1.3422 | 0.7797 | 0.8848 |
| L-Homoarginine | 1.4767 | 1.1645 | 0.4765 | 1.0407 |
| L-Homocitrulline | 1.5770 | 1.2688 | 0.3922 | 0.8413 |
| L-Isoleucine | 1.5437 | 1.7541 | 0.1920 | 0.6734 |
| L-Kynurenine | 1.5595 | 1.5508 | 0.0782 | 0.8743 |
| L-Leucine | 1.4935 | 1.8668 | 0.2074 | 0.6215 |
| L-Lysine | 0.8702 | 1.4172 | 0.7758 | 0.9579 |
| L-Methionine | 1.0658 | 1.3137 | 0.2459 | 1.2497 |
| L-Norvaline | 1.4098 | 1.8506 | 0.2229 | 0.6779 |
| L-Phenylalanine | 1.4145 | 1.7195 | 0.2462 | 0.7465 |
| L-Proline | 1.0650 | 1.4926 | 0.5268 | 0.9437 |
| L-Pyroglutamic acid | 0.9620 | 1.2426 | 0.6438 | 1.1011 |
| L-Serine | 0.7650 | 1.2613 | 0.8491 | 1.0831 |
| L-Threonine | 0.6697 | 1.0950 | 0.9525 | 1.1885 |
| L-Tryptophan | 1.3325 | 1.8243 | 0.0450 | 0.8654 |
| L-Tyrosine | 1.1824 | 1.5887 | 0.2544 | 0.9830 |
| L-Valine | 1.4111 | 1.8637 | 0.2167 | 0.6724 |
| N2-Acetyl- L-lysine | 1.1423 | 1.3154 | 0.3800 | 1.1082 |
| N2-Acetyl-L-ornithine | 2.2532 | 1.1899 | 0.3992 | 0.4385 |
| N6,N6,N6-Trimethyl-L-lysine | 0.9502 | 0.9341 | 1.0855 | 1.0202 |
| N-Acetyl-L-aspartic acid | 1.1730 | 0.9910 | 0.8588 | 1.0107 |
| N-Acetyl-L-glutamate | 1.0629 | 1.1926 | NA | 0.7444 |
| N-Acetyl-L-glutamine | 0.7002 | 1.0286 | NA | 1.2712 |
| Nicotinamide | 0.7956 | 0.8666 | 1.1862 | 1.1011 |
| Nicotinamide mononucleotide | 0.6611 | 1.4011 | 0.8816 | 1.0872 |
| N-methylethanolamine | 1.2880 | 1.1973 | 0.0523 | 0.6938 |
| N,N-Dimethylarginine | 1.2294 | 1.2733 | 0.5145 | 0.9885 |
| O-Phosphoethanolamine | 0.7269 | 1.0629 | 1.2291 | 0.9875 |
| O-Phospho-L-serine | 0.4449 | 1.6849 | 0.9543 | 0.9808 |
| Oxidized glutathione | 0.3089 | 1.6728 | 1.3274 | 0.7909 |
| Pantothenate | 0.2818 | 0.9517 | 1.5536 | 1.1419 |
| Phosphocholine | 0.8733 | 0.9173 | 1.3035 | 0.9373 |
| Propionic acid | 1.2687 | 1.1232 | 0.8903 | 0.8119 |
| Pyridoxal | 0.9637 | 1.3037 | NA | 0.7327 |
| Pyruvic acid | 0.9597 | 1.9400 | 0.1319 | 0.9789 |
| rac 3-Hydroxyisobutyric acid | 2.1974 | 1.3468 | 0.0824 | 0.5823 |
| Reduced glutathione | 0.8983 | 0.6961 | 1.4310 | 0.9831 |
| S-Adenosyl-L-homocysteine | 1.1142 | 0.8527 | 1.1269 | 0.9375 |
| S-Adenosylmethionine | 0.8884 | 0.7257 | 1.3581 | 1.0186 |
| Taurine | 0.7025 | 0.8666 | 1.3651 | 1.0438 |
| Thymidine | NA | NA | NA | NA |
| Trigonelline | 1.6998 | 0.8230 | 0.0580 | 1.0294 |
| Uracil | 1.1533 | 1.1227 | NA | 0.7240 |
| Uridine | 1.2288 | 1.3196 | 0.4133 | 1.0255 |
| Urocanic acid | 0.9632 | 1.2358 | 1.0454 | 0.8403 |
| Xanthine | 0.2199 | 0.4898 | 0.3203 | 2.0599 |
| Xanthosine | 1.8911 | 0.8349 | 0.1200 | 1.2222 |
Factors:
| F1 | Animal:db/db | Treatment:Cana |
| F2 | Animal:db/db | Treatment:vehicle |
| F3 | Animal:db/+ | Treatment:Cana |
| F4 | Animal:db/+ | Treatment:vehicle |
