Data for (Study ST002805)
(Analysis AN004561)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 |
---|---|---|---|---|
1,3-diphopshateglycerate | 1.4053 | 0.9495 | 1.2571 | 0.5654 |
1-Methyladenosine | 1.2209 | 0.7438 | 0.7429 | 1.2748 |
1-Methyl-Histidine | 1.4100 | 0.5961 | 0.9074 | 1.0896 |
2,3-dihydroxybenzoic acid | 1.1777 | 0.2850 | 1.3310 | 0.9376 |
2,3-Diphosphoglyceric acid | NA | 0.9677 | 1.0161 | NA |
2-Aminooctanoic acid | 1.4183 | 0.9311 | 0.7396 | 1.0857 |
2-dehydro-D-gluconate | 0.8791 | 1.2826 | 1.1388 | 0.7803 |
2-deoxyglucose-6-phosphate | 0.8930 | 0.5381 | 1.2860 | 0.9984 |
2-Hydroxy-2-methylbutanedioic acid | 0.9714 | 0.7506 | 1.1341 | 1.0049 |
2-hydroxygluterate | 1.0976 | 1.0461 | 1.0336 | 0.8946 |
2-Isopropylmalic acid | 0.4861 | 3.4989 | 0.4832 | 0.5243 |
2-ketohaxanoic acid | 0.9330 | NA | 1.1348 | 0.8987 |
2-keto-isovalerate | 0.8361 | 0.9509 | 1.1990 | 0.9076 |
2-oxo-4-methylthiobutanoate | 0.8882 | 1.7368 | 0.5362 | 1.1513 |
2-oxobutanoate | 0.7170 | 1.4734 | 1.1096 | 0.7952 |
3-hydroxybuterate | 0.5202 | 1.3125 | 0.8921 | 1.1915 |
3-methylphenylacetic acid | 0.5428 | 0.2813 | 1.0598 | 1.5281 |
3-phosphoglycerate | 0.6820 | 1.0538 | 1.0937 | 1.0384 |
3-phospho-serine | NA | 0.8891 | 1.1109 | 0.8890 |
3-S-methylthiopropionate | NA | 1.4998 | 0.5002 | NA |
4-aminobutyrate | NA | NA | NA | 1.0000 |
4-phosphopantothenate | NA | 0.5003 | 1.1247 | 1.2503 |
4-Pyridoxic acid | 0.7974 | 1.3543 | 1.0607 | 0.8634 |
5-methoxytryptophan | 0.4289 | 1.9998 | 0.5713 | 1.0000 |
5-methyl-THF | NA | NA | NA | NA |
5-phosphoribosyl-1-pyrophosphate | NA | NA | NA | 1.0000 |
6-phospho-D-gluconate | 1.0753 | 1.2313 | 1.3854 | 0.3079 |
7,8-dihydrofolate | NA | NA | NA | NA |
7-methylguanosine | 0.7200 | 1.1390 | 1.1405 | 0.9299 |
acadesine | 1.0000 | NA | NA | NA |
acetoacetate | 0.6919 | 1.0692 | 1.0051 | 1.1143 |
acetoacetyl-CoA-posi | NA | NA | NA | NA |
Acetylcarnitine DL | 0.9485 | 1.0533 | 1.3872 | 0.6119 |
acetyl-CoA-posi | NA | NA | NA | NA |
Acetyllysine | 0.4471 | 0.9618 | 0.8909 | 1.4046 |
acetylphosphate | 1.6041 | NA | 0.2734 | 1.1224 |
aconitate | 0.7565 | 0.7641 | 1.0863 | 1.1534 |
adenine | 0.9527 | 0.8572 | 1.0239 | 1.0712 |
adenosine | 0.6856 | 0.5401 | 1.8613 | 0.5259 |
adenosine 5-phosphosulfate | NA | NA | NA | NA |
Adenylosuccinate | 0.7905 | 1.1368 | 1.1782 | 0.8582 |
ADP-D-glucose | NA | NA | NA | 1.0000 |
ADP-nega | NA | NA | 1.0000 | NA |
a-ketoglutarate | 1.1800 | 0.6967 | 1.0346 | 1.0270 |
alanine | 1.1005 | 0.6022 | 1.0144 | 1.1342 |
allantoate | NA | NA | 1.5084 | 0.7458 |
allantoin | 1.1608 | 0.6786 | 0.5532 | 1.5271 |
Aminoadipic acid | 0.9225 | 0.4342 | 1.2255 | 1.0961 |
aminoimidazole carboxamide ribonucleotide | NA | NA | NA | NA |
AMP | NA | NA | 1.0000 | NA |
anthranilate | 0.4915 | 0.9602 | 1.1190 | 1.1552 |
arginine | 1.0161 | 0.8386 | 0.9772 | 1.0954 |
arginosuccinic acid | 1.2877 | 0.9863 | 0.9907 | 0.8723 |
Ascorbic acid | 0.9050 | 0.5996 | 1.1788 | 1.0689 |
asparagine | 1.1334 | 0.7245 | 1.0638 | 1.0073 |
aspartate | 0.8063 | 1.1786 | 1.0563 | 0.9513 |
ATP-nega | NA | NA | 1.0000 | NA |
Atrolactic acid | 1.0489 | 1.3607 | 0.5876 | 1.2076 |
betaine | 0.7961 | 1.2315 | 1.1352 | 0.8509 |
betaine aldehyde | 0.6096 | 1.0334 | 1.2506 | 0.9279 |
biotin | 0.7949 | 2.2624 | 0.6271 | 0.8443 |
Carbamoyl phosphate | 2.0596 | 0.5108 | 0.8468 | 0.8680 |
carnitine | 0.9602 | 1.0027 | 0.8391 | 1.1795 |
CDP-choline | NA | NA | NA | NA |
CDP-ethanolamine | NA | NA | NA | NA |
CDP-nega | 2.0909 | 0.6615 | 0.8815 | 0.4846 |
Cellobiose | NA | NA | NA | NA |
cholesterol | 1.1025 | 1.5983 | 0.8181 | 0.8315 |
cholesteryl sulfate | 1.1218 | 0.4649 | 1.1088 | 1.0979 |
Cholic acid | 1.4461 | 0.4245 | 1.1796 | 0.8851 |
choline | 1.2697 | 0.0001 | 1.1976 | 1.1675 |
Citraconic acid/itaconic acid | 1.5544 | 0.1708 | 1.2628 | 0.8746 |
citrate | 1.1221 | 0.2425 | 1.4184 | 0.8993 |
citrate-isocitrate | 1.4766 | 0.2657 | 1.5036 | 0.6253 |
citrulline | 1.0785 | 0.0058 | 1.2042 | 1.2536 |
CMP | NA | NA | NA | 1.0000 |
coenzyme A-posi | 0.5957 | 1.3905 | NA | 1.0069 |
creatine | 1.5838 | 0.5397 | 0.8666 | 1.0716 |
Creatinine | 1.1981 | 1.1933 | 0.9732 | 0.6621 |
CTP-nega | NA | NA | 1.0000 | NA |
cyclic-AMP | 0.8607 | 0.4430 | 1.4748 | 0.8733 |
cyclic bis(3->5) dimeric GMP | 1.0000 | NA | NA | NA |
cystathionine | 0.8256 | NA | 1.3331 | 0.5081 |
cysteine | 1.2994 | 0.8898 | 0.8112 | 1.0942 |
cysteine sulfinate | 1.0237 | 0.7315 | 0.8773 | 1.2451 |
Cystine | 0.8995 | 0.5860 | 1.0364 | 1.2209 |
cytidine | 1.1666 | 0.3480 | 1.8122 | 0.4305 |
cytosine | 1.2163 | 0.6575 | 0.9909 | 1.0723 |
dAMP | NA | NA | NA | NA |
dATP-nega | NA | NA | NA | NA |
dCDP-nega | NA | NA | NA | NA |
dCMP | NA | NA | NA | NA |
dCTP-nega | 1.0000 | 1.0000 | NA | NA |
dehydroascorbic acid | 0.9896 | 2.7473 | 0.2468 | 0.8847 |
deoxyadenosine | NA | 1.1427 | 0.4762 | 1.9049 |
Deoxycholic acid | NA | NA | NA | NA |
deoxyguanosine | 1.5392 | 1.5015 | 0.7101 | 0.7695 |
deoxyinosine | 0.5333 | 2.0003 | 0.7995 | 0.6668 |
deoxyribose-phosphate | NA | NA | 0.6693 | 1.3307 |
deoxyuridine | NA | NA | NA | NA |
dephospho-CoA-nega | 1.8378 | NA | 0.4324 | 0.8649 |
dephospho-CoA-posi | NA | NA | NA | NA |
D-erythrose-4-phosphate | 1.3816 | 0.4612 | 1.0879 | 0.9907 |
dGDP-nega | 0.7058 | NA | 1.2353 | 1.0589 |
D-glucarate | NA | 0.7447 | 0.7478 | 1.5075 |
D-gluconate | 0.9547 | 0.9353 | 1.1159 | 0.9391 |
D-glucono-?-lactone-6-phosphate | 0.7172 | 0.6272 | 0.9962 | 1.3316 |
D-glucosamine-1-phosphate | NA | 1.0000 | NA | NA |
D-glucosamine-6-phosphate | NA | NA | 1.0908 | 0.9092 |
D-glyceraldehdye-3-phosphate | 0.6390 | 1.1191 | 1.1169 | 1.0625 |
dGMP | NA | 1.2002 | NA | 0.7998 |
dGTP | 0.7510 | NA | 1.1245 | NA |
dihydroorotate | 0.6133 | 1.7728 | 1.0892 | 0.7178 |
dihydroxy-acetone-phosphate | 1.9567 | NA | 0.5676 | 0.9082 |
Diiodothyronine | NA | NA | NA | NA |
dimethylglycine | 1.2643 | 0.0003 | 1.2188 | 1.1489 |
DL-Pipecolic acid | 0.9587 | 0.6288 | 1.1694 | 1.0368 |
D-sedoheptulose-1-7-phosphate | 0.8439 | 0.3253 | 1.8578 | 0.5576 |
dTDP-nega | NA | 0.5494 | NA | 1.2253 |
dTMP | NA | NA | NA | 1.0000 |
dTMP-nega | 0.2603 | 4.0516 | 0.4339 | 0.4101 |
dTTP-nega | NA | NA | NA | NA |
dUMP-nega | NA | 1.0000 | NA | NA |
dUTP-nega | NA | NA | 1.0000 | NA |
ethanolamine | NA | NA | NA | NA |
FAD | NA | NA | NA | NA |
Flavone | 1.1281 | 1.1365 | 1.0256 | 0.8421 |
FMN | NA | NA | NA | NA |
folate | 0.6714 | 0.8334 | 0.8196 | 1.4281 |
fructose-1,6-bisphosphate | 0.6803 | 0.6849 | 1.1095 | 1.2079 |
fructose-6-phosphate | NA | 1.0197 | 0.7457 | 1.4889 |
fumarate | 1.2129 | 0.9069 | 1.1017 | 0.8384 |
GDP-nega | NA | NA | NA | NA |
Geranyl-PP | NA | NA | NA | NA |
glucono-?-lactone | 1.2738 | 0.6365 | 1.0449 | NA |
glucosamine | 1.1093 | 0.7957 | 1.0213 | 1.0262 |
glucose-1-phosphate | 0.9689 | 1.0496 | 1.0575 | 0.9332 |
glucose-6-phosphate | 0.9802 | 1.5269 | 0.6008 | 0.9460 |
glutamate | 0.9311 | 0.7479 | 1.1280 | 1.0325 |
glutamine | 1.0220 | 0.8079 | 1.0755 | 1.0095 |
glutathione | 0.7913 | 1.6007 | 0.9782 | 0.8258 |
glutathione disulfide-nega | 1.2511 | 0.7474 | 0.8940 | 1.1067 |
glutathione disulfide-posi | 1.2867 | 1.2195 | 0.8367 | 0.8204 |
glutathione-nega | 0.8492 | 0.8422 | 1.1401 | 1.0143 |
glycerate | 1.0325 | 0.7375 | 1.0139 | 1.1011 |
Glycerophosphocholine | 1.3183 | 0.8013 | 0.9545 | 0.9857 |
glycine | NA | NA | NA | NA |
glycolate | 0.7324 | 0.4971 | 1.6451 | 0.7402 |
glyoxylate | 1.5062 | 0.5492 | 0.8238 | 1.1484 |
GMP | NA | NA | NA | NA |
GTP-nega | NA | NA | 1.0000 | NA |
Guanidoacetic acid | 1.0262 | 0.5917 | 1.1713 | 1.0197 |
guanine | 0.7005 | 0.7456 | 1.1210 | 1.1559 |
guanosine | 1.2539 | 0.6948 | 1.0802 | 0.9856 |
guanosine 5-diphosphate,3-diphosphate | NA | NA | NA | 1.0000 |
hexose-phosphate | 0.9397 | 0.8336 | 1.0921 | 1.0213 |
histidine | 1.1685 | 0.7040 | 1.0279 | 1.0359 |
histidinol | NA | NA | 1.0000 | NA |
HMG-CoA_pos | NA | NA | NA | NA |
homocysteic acid | 1.6009 | 0.4307 | 0.6763 | 1.3079 |
homocysteine | 0.8738 | NA | 0.9533 | 1.1098 |
homoserine | 1.6444 | 0.5654 | 0.9303 | 0.9648 |
Hydroxyisocaproic acid | 1.1435 | 0.9013 | 0.9992 | 0.9784 |
Hydroxyphenylacetic acid | 1.3527 | 0.0685 | 0.9421 | 1.3472 |
hydroxyphenylpyruvate | 1.0340 | 0.9250 | 1.0116 | 1.0089 |
hydroxyproline | 1.4231 | 0.4351 | 0.6779 | 1.3930 |
hypoxanthine | 0.8268 | 2.0907 | 0.6872 | 0.7081 |
IDP-nega | NA | NA | NA | NA |
Imidazoleacetic acid | 0.8578 | 0.8721 | 1.0548 | 1.0803 |
IMP | NA | NA | NA | NA |
indole | 0.8568 | 0.3230 | 1.3533 | 1.0568 |
Indole-3-carboxylic acid | 0.7532 | 0.4489 | 1.4642 | 0.9347 |
Indoleacrylic acid | 0.9615 | 0.5880 | 0.9973 | 1.2280 |
inosine | 1.0841 | 0.7652 | 0.8997 | 1.1757 |
isocitrate | 0.9061 | 1.3851 | 0.7697 | 1.0847 |
itaconic acid | 1.6536 | 0.3674 | 1.0748 | 0.9147 |
Kynurenic acid | 1.1745 | 0.0122 | 0.4230 | 1.9836 |
Kynurenine | 0.6669 | 0.5466 | 0.9940 | 1.3962 |
lactate | 1.2274 | 0.7268 | 0.7103 | 1.3126 |
L-arginino-succinate | 0.7918 | 0.8429 | 0.9909 | 1.1917 |
leucine-isoleucine | 1.0546 | 0.7134 | 1.0902 | 1.0258 |
lipoate | NA | NA | NA | NA |
lysine | 0.9921 | 0.5893 | 1.2117 | 0.9976 |
malate | 0.6811 | 0.7287 | 0.9894 | 1.3057 |
Maleic acid | 0.6747 | 0.9913 | 1.1466 | 1.0204 |
malonyl-CoA-posi | NA | NA | NA | NA |
methionine | 0.9248 | 0.9531 | 1.1291 | 0.9319 |
Methionine sulfoxide | 1.0676 | 0.8443 | 1.0096 | 1.0344 |
Methylcysteine | 0.9527 | 0.8572 | 1.0239 | 1.0712 |
Methylmalonic acid | 0.8810 | 0.8978 | 1.4591 | 0.6515 |
methylnicotinamide | 1.1930 | NA | 1.1000 | 0.8035 |
myo-inositol | 1.1488 | 0.8573 | 0.9512 | 1.0458 |
N6-Acetyl-L-lysine | 1.4188 | 0.4946 | 1.1884 | 0.7097 |
N-acetyl-glucosamine | NA | 0.9239 | 1.0761 | NA |
N-acetyl-glucosamine-1-phosphate | 1.7619 | 0.8926 | 0.3953 | 1.2775 |
N-acetyl-glutamate | 1.1611 | 0.0795 | 1.2275 | 1.1522 |
N-acetyl-glutamine | 0.4106 | 0.1051 | 1.2470 | 1.4951 |
N-Acetyl-L-alanine | 1.8470 | 0.2693 | 1.0750 | 0.8669 |
N-acetyl-L-aspartic acid | 1.3256 | NA | NA | 0.6744 |
N-acetyl-L-aspartylglutamic acid | NA | NA | NA | NA |
N-acetyl-L-ornithine | 0.8736 | 0.7272 | 1.2764 | 0.9232 |
N-Acetylputrescine | NA | 0.9539 | 0.9820 | 1.0411 |
N-acetyl spermidine | NA | NA | 0.5568 | 1.2216 |
N-acetyl spermine | 0.7144 | 1.5642 | 0.5837 | 1.2770 |
NADH | NA | NA | NA | NA |
NADH-nega | NA | NA | NA | NA |
NAD+_nega | 1.0000 | NA | NA | NA |
NADPH | NA | NA | NA | NA |
NADPH-nega | NA | NA | NA | NA |
NADP+_nega | NA | NA | NA | NA |
NAD+_posi | NA | NA | NA | NA |
NADP+_posi | NA | NA | NA | NA |
N-carbamoyl-L-aspartate | NA | NA | NA | NA |
N-carbamoyl-L-aspartate-nega | NA | NA | 1.0632 | 0.9368 |
Ng,NG-dimethyl-L-arginine | 1.4827 | 0.4336 | 0.8824 | 1.1595 |
nicotinamide | 1.1604 | 0.7228 | 1.0003 | 1.0581 |
Nicotinamide Riboside | 0.9683 | 1.8485 | 0.7044 | 0.8872 |
Nicotinamide ribotide | 1.2136 | 1.3651 | 0.9098 | 0.6018 |
nicotinate | 1.2486 | 0.5809 | 1.0254 | 1.0599 |
O8P-O1P | 0.6600 | 0.6605 | 1.4313 | 0.9084 |
O-acetyl-L-serine | NA | NA | 1.0000 | NA |
OBP | 0.8882 | 1.1595 | 1.0739 | 0.9022 |
ornithine | 1.0662 | 0.2795 | 1.2113 | 1.1158 |
orotate | 0.6411 | 0.2414 | 0.7172 | 1.8415 |
orotidine-5-phosphate | NA | 1.1480 | 1.1275 | 0.5970 |
oxaloacetate | 1.7724 | 0.5887 | 1.3528 | 0.4666 |
p-aminobenzoate | 1.2318 | 0.4477 | 1.5343 | 0.6259 |
pantothenate | 0.7516 | 1.2685 | 0.9703 | 1.0196 |
phenylalanine | 1.0804 | 0.3967 | 1.2529 | 1.0086 |
Phenyllactic acid | 0.8739 | 0.8363 | 1.1359 | 1.0090 |
Phenylpropiolic acid | 0.0561 | 5.7485 | 0.0481 | 0.0496 |
phenylpyruvate | 1.1480 | 0.8497 | 0.8686 | 1.1326 |
phosphocreatine | 1.0093 | 1.3422 | 0.8539 | 0.9704 |
phosphoenolpyruvate | 1.2442 | 0.7558 | NA | NA |
Phosphorylcholine | 1.1783 | 1.3552 | 0.9379 | 0.7953 |
p-hydroxybenzoate | 0.6447 | 0.4777 | 1.2239 | 1.2149 |
prephenate | NA | NA | NA | NA |
proline | 1.2442 | 0.7660 | 0.9865 | 1.0084 |
propionyl-CoA-posi | NA | NA | NA | NA |
purine | 1.1549 | 0.5463 | 1.1081 | 1.0413 |
putrescine | 0.9458 | 1.2761 | 1.6022 | 0.5880 |
Pyridoxamine | NA | 0.6320 | 1.1840 | NA |
pyridoxine | 1.3023 | 0.5733 | 1.0815 | 0.9807 |
Pyroglutamic acid | 1.0376 | 0.8527 | 1.0800 | 0.9748 |
Pyrophosphate | 0.3528 | 3.4191 | 0.7077 | 0.4064 |
pyruvate | 0.8257 | 0.4550 | 1.3456 | 1.0141 |
quinolinate | 1.9868 | 1.8384 | 0.8791 | 0.2083 |
retinoic acid | NA | NA | NA | NA |
riboflavin | 0.9752 | 0.7020 | 1.2512 | 0.9102 |
ribose-phosphate | 1.2932 | 0.2849 | 0.9378 | 1.2731 |
S-adenosyl-L-homocysteine-nega | 2.2859 | NA | 0.7857 | 0.5714 |
S-adenosyl-L-homoCysteine-posi | NA | NA | 0.8571 | 1.0714 |
S-adenosyl-L-methioninamine | 1.1163 | 1.2176 | NA | 0.6661 |
S-adenosyl-L-methionine | NA | NA | NA | NA |
sarcosine | 1.1504 | 0.6803 | 0.9589 | 1.1257 |
SBP | 1.3682 | 0.4660 | 1.2032 | 0.8796 |
serine | 1.0113 | 0.6313 | 1.0591 | 1.1196 |
shikimate | 2.0056 | 0.3235 | 0.7293 | 1.1061 |
shikimate-3-phosphate | NA | NA | NA | NA |
S-methyl-5-thioadenosine | 0.7652 | NA | 1.1175 | 1.1174 |
sn-glycerol-3-phosphate | 1.0397 | 1.4943 | 0.7928 | 0.9402 |
spermidine | 0.8850 | 1.1994 | 0.7805 | 1.1773 |
spermine | NA | 2.6329 | 0.4014 | 0.5644 |
S-ribosyl-L-homocysteine-nega | NA | NA | NA | 1.0000 |
S-ribosyl-L-homocysteine-posi | 1.0446 | 0.9400 | 0.9084 | 1.0993 |
succinate | 1.3327 | 0.7697 | 1.2695 | 0.6794 |
succinyl-CoA-posi | NA | NA | NA | NA |
taurine | 0.9057 | 1.1096 | 1.0288 | 0.9636 |
Taurodeoxycholic acid | 1.0711 | 0.7063 | 0.9742 | 1.1371 |
thiamine | NA | NA | NA | NA |
thiamine-phosphate | NA | NA | NA | NA |
Thiamine pyrophosphate | NA | 0.6643 | NA | 1.1679 |
threonine | 1.0862 | 0.6411 | 1.0834 | 1.0530 |
thymidine | NA | NA | NA | NA |
thymine | NA | 2.9213 | 0.4316 | 0.6078 |
trans, trans-farnesyl diphosphate | 1.1110 | NA | 0.8890 | NA |
trehalose-6-Phosphate | NA | NA | NA | 1.0000 |
trehalose-sucrose | NA | NA | NA | 1.0000 |
tryptophan | 0.9749 | 0.4223 | 1.2439 | 1.0575 |
tyrosine | 0.9068 | 0.7622 | 1.1720 | 0.9935 |
UDP-D-glucose | NA | NA | NA | NA |
UDP-D-glucuronate | NA | NA | NA | 1.0000 |
UDP-N-acetyl-glucosamine | NA | NA | NA | NA |
UDP-nega | NA | NA | 1.0000 | NA |
UMP | NA | 1.1147 | 0.8853 | NA |
uracil | 1.0586 | 0.9393 | 1.0235 | 0.9775 |
Urea | 1.1249 | 1.3589 | 0.9223 | 0.8357 |
Uric acid | 0.4197 | 2.0962 | 0.4215 | 1.0313 |
uridine | 1.9932 | 0.6975 | 0.7629 | 0.8918 |
UTP-nega | 1.2408 | NA | 0.8796 | NA |
valine | 0.7728 | 0.8431 | 1.0944 | 1.0977 |
xanthine | 1.7052 | 0.4267 | 0.8996 | 1.0344 |
xanthosine | 1.2573 | 1.1279 | 0.7959 | 1.0115 |
xanthosine-5-phosphate | NA | NA | NA | NA |
Xanthurenic acid | 1.3262 | 1.5931 | 0.8021 | 0.7382 |
Factors:
F1 | Sex:F | Treatment:Control |
F2 | Sex:F | Treatment:IL-1B |
F3 | Sex:M | Treatment:Control |
F4 | Sex:M | Treatment:IL-1B |