Data for (Study ST002852)

(Analysis AN004673)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4
6-phosphogluconic acid 1.3227 0.8266 0.9156 0.8356
acetyl-CoA 1.5282 0.9226 0.6002 0.6485
adenylosuccinic acid 1.3892 0.8281 0.6880 0.9499
ADP 1.3587 0.9409 0.7147 0.7859
AICAR 1.4553 1.0468 0.6074 0.5557
alpha-ketoglutarate 1.1323 1.2897 0.4387 0.8579
AMP 1.3168 0.9756 0.6828 0.8299
arachidic acid 0.4570 0.6411 1.6701 1.8331
argininosuccinate 1.6665 0.8167 0.5944 0.6002
ascorbate 1.4075 1.0250 0.4696 0.8095
aspartate 1.1999 0.8250 0.8606 1.0979
ATP 1.2430 1.0414 0.7989 0.7272
CAIR 0.8162 1.3805 0.6435 1.0286
carbamoyl-aspartate 0.7808 0.9516 0.6670 1.6680
CDP 1.1160 0.9751 0.8387 1.0095
CDP-ethanolamine 1.3851 0.9668 0.6131 0.8003
cis-aconitate 1.0311 1.0391 0.6131 1.2698
citrate / isocitrate 1.0953 1.1011 0.4849 1.1877
CMP 1.0546 0.9284 0.8567 1.1716
CoA 1.4648 0.8917 0.6889 0.7168
CTP 1.0704 1.0094 0.8154 1.0517
cysteine 0.6358 0.9882 1.4031 1.2236
cystine 0.9780 1.0348 1.1922 0.7864
cytidine 1.1013 0.9625 0.9363 0.9574
dCTP 1.0440 0.7635 1.3583 0.9625
dihydroorotate 0.5618 0.7788 0.9842 1.9634
dihydroxyacetone-phosphate 1.0130 1.1092 0.9586 0.8377
dTMP 0.8374 0.8041 1.2837 1.3139
dTTP 0.6377 0.8195 1.1398 1.5141
FGAR 0.5651 0.9275 0.3915 1.9615
fructose 1.2597 1.2137 0.4610 0.7499
fructose-1;6-bisphosphate 1.5037 0.8876 0.7235 0.6244
fructose-1-phosphate 1.5361 0.9330 0.4750 0.7431
fructose-6-phosphate 1.7475 0.8099 0.6346 0.4365
fumarate 1.3206 0.8750 0.8246 0.8495
gamma-amino-butyrate 1.2291 1.0039 0.7224 0.8894
GAR 1.3289 1.1906 0.4390 0.6952
GDP 1.3913 1.0327 0.5917 0.7015
glucose 1.2536 1.2156 0.4649 0.7532
glucose-6-phosphate 1.5297 0.8545 0.9030 0.4568
glutamate 1.2644 0.9604 0.7453 0.8801
glutamine 1.2795 0.8976 0.9172 0.7876
glyceraldehyde-3-phosphate 1.2208 1.4319 0.2805 0.6317
glycerol-3-phosphate 1.2790 0.9419 0.6664 0.9654
GSH 1.4590 0.9243 0.6034 0.7577
GSSG 1.0394 0.9009 0.8447 1.2549
GTP 1.2498 1.1304 0.6872 0.6791
guanosine 1.4971 1.0329 0.5616 0.5551
histidine 1.1439 1.0305 0.6872 1.0221
hydroxyglutarate 0.8541 0.8541 1.0544 1.4320
hypotaurine 1.3669 0.9775 0.5533 0.8727
IMP 1.0467 1.0635 0.7705 1.0458
inosine 1.3508 0.9969 0.8238 0.5967
lactate 1.3085 0.8676 0.8013 0.9053
lauric acid 0.9339 0.8654 0.9361 1.3984
malate 1.3091 0.8771 0.8564 0.8333
myristic acid 0.9481 0.8521 1.2268 1.1061
N-acetylglucosamine-phosphate 1.1651 1.0320 0.7588 0.9128
N-acetylglutamate 1.5957 1.1444 0.2719 0.4946
NADH 1.3023 0.7823 1.1013 0.7577
oleic acid 0.6871 1.2420 1.1181 1.0001
orotate 0.5546 0.8283 1.0916 1.9369
palmitic acid 0.9120 0.9746 1.1372 1.0519
phosphate 1.0108 0.9733 1.0414 0.9851
phosphatidylethanolamine 0.8091 0.7858 NA 1.4051
phosphocreatine 1.3435 0.6937 0.7098 1.2282
phosphoenolpyruvate 0.7385 1.7943 0.3253 0.7868
phosphoglycerate 1.1567 0.9580 1.0474 0.7614
phosphoribosylamine 1.0432 1.0995 0.9189 0.8764
phosphorylethanolamine 1.5014 1.1199 0.3500 0.6144
phosphoserine 1.0995 0.7553 1.0569 1.2040
pyruvate 1.1620 1.0775 0.6733 0.9275
quinolinic acid 0.9670 0.9477 0.7998 1.3424
rib/ribul/xylul-ose-phosphate 0.9955 1.1135 1.0283 0.7899
S-(1;2-Dicarboxyethyl)glutathione 1.2846 0.8128 1.0183 0.8254
S-(2-Succinyl)-L-cysteine 1.0025 1.1487 0.6194 1.1286
saccharopine 1.5736 1.0826 0.3360 0.5703
S-adenosyl-homocysteine 1.2149 0.9607 0.8256 0.8816
sedoheptulose-7-phosphate 1.5639 0.8703 0.7303 0.5461
sorbitol 1.8461 0.8541 0.2874 0.5457
stearic acid 0.8520 0.9127 1.2686 1.1236
succinate 1.1923 0.6835 0.9801 1.2270
taurine 1.1356 0.9445 0.7604 1.1061
trifluoromethanesulfonate 0.9418 1.0212 1.0016 1.0601
tryptophan 1.2151 0.9542 0.7974 0.9205
tyrosine 1.2923 0.9675 0.7002 0.8668
UDP-glucuronic acid 1.3969 0.9196 0.6762 0.7962
UDP-N-acetylglucosamine 1.4561 1.0964 0.4553 0.6238
UMP 1.2607 0.9017 0.7073 1.0220
uric acid 1.0627 1.1325 0.6583 1.0162
UTP 1.3195 0.9129 0.8314 0.7812
XMP 0.7219 1.0320 0.8916 1.4258
xylonic acid 1.0458 1.0613 0.7099 1.1116
xylulose 1.2057 0.9887 0.7451 0.9309
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Factors:

F1Treatment:Enzalutamide | Technical Replicate (Region of Tumor):1
F2Treatment:Enzalutamide | Technical Replicate (Region of Tumor):2
F3Treatment:Vehicle | Technical Replicate (Region of Tumor):1
F4Treatment:Vehicle | Technical Replicate (Region of Tumor):2
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