Data for (Study ST002814)
(Analysis AN004705)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|
| 1-methylnicotinamide | NA | NA | 0.9772 | NA | NA | NA | NA | 1.0208 | NA | NA |
| 3-hydroxy-trimethyllysine | 2.1397 | 0.4484 | 0.3684 | 0.8998 | 0.3636 | 2.3318 | 0.4151 | 0.5446 | 1.0973 | 0.3086 |
| 5^-methylthioadenosine | 0.8444 | 0.4029 | 1.6776 | 1.1499 | 0.0174 | 1.1291 | 0.3826 | 1.9568 | 0.9195 | 0.0170 |
| acetyl-carnitine | 0.3493 | 0.2484 | 0.4715 | 2.9677 | 0.3038 | 0.4282 | 0.2397 | 0.5666 | 3.0534 | 0.3096 |
| adenosine | 0.3857 | 1.3526 | 1.5388 | 0.9228 | 0.0204 | 0.4574 | 1.3638 | 1.6278 | 0.8572 | 0.0197 |
| AIR | 0.5429 | 1.4396 | 1.6455 | 0.2585 | NA | 0.3946 | 1.5057 | 1.4817 | 0.3938 | NA |
| alanine | 0.8149 | 1.0593 | 1.0574 | 0.8975 | 1.5859 | 0.8747 | 1.0149 | 1.1992 | 0.8516 | 1.2666 |
| arginine | 1.1158 | 0.7253 | 0.7813 | 0.9417 | 1.7446 | 1.2518 | 0.7068 | 0.9962 | 1.0588 | 1.7175 |
| asparagine | 0.8580 | 0.8613 | 1.2253 | 0.8787 | 1.3640 | 0.9660 | 0.8618 | 1.4451 | 0.7977 | 0.9750 |
| aspartate-pos | 0.6555 | 1.3451 | 0.8582 | 1.1475 | 0.0743 | 0.8632 | 1.3117 | 1.2022 | 1.0726 | 0.0768 |
| betaine | 0.2339 | 0.2077 | 0.5785 | 3.0939 | 0.2502 | 0.2690 | 0.1835 | 0.6167 | 3.1874 | 0.2128 |
| caffeine | NA | NA | NA | 1.0686 | NA | NA | NA | NA | 0.9409 | NA |
| carnitine | 0.3033 | 0.4148 | 0.4388 | 2.8864 | 0.1031 | 0.3633 | 0.3738 | 0.5357 | 3.1101 | 0.1096 |
| CDP-choline | 0.8490 | NA | 1.1580 | 0.9753 | NA | 0.9501 | NA | 1.2901 | 0.7752 | NA |
| choline | 0.4057 | 0.4681 | 0.7456 | 2.5524 | 0.3436 | 0.2345 | 0.5256 | 0.9333 | 2.4419 | 0.3396 |
| citrulline | 0.9255 | 0.7569 | 0.5681 | 0.7747 | 4.2773 | 1.0493 | 0.6330 | 0.6710 | 0.8760 | 4.2474 |
| creatine | 1.5232 | 0.7085 | 0.8273 | 1.0018 | 0.4594 | 1.6672 | 0.6576 | 0.8287 | 1.0456 | 0.5288 |
| creatinine | 0.8981 | 0.5596 | 0.7124 | 1.1816 | 3.0039 | 1.0754 | 0.5189 | 0.8615 | 1.1164 | 2.9716 |
| cystathionine | 0.9065 | 0.0570 | 2.9926 | 0.2267 | 0.3493 | 1.1343 | 0.0558 | 2.8649 | 0.2175 | 0.2843 |
| gamma-butyrobetaine | 0.3244 | 0.3060 | 0.3795 | 2.5803 | 0.1107 | 0.3765 | 0.3047 | 0.5317 | 3.5507 | 0.1347 |
| glycerophosphocholine | 0.9962 | 0.9695 | 1.4722 | 1.1730 | 0.0514 | 0.9571 | 0.8213 | 1.4416 | 0.7218 | 0.0454 |
| glycine | 0.8206 | 0.6945 | 1.7809 | 0.4979 | 0.1223 | 0.8290 | 0.6399 | 2.2530 | 0.5330 | 1.4505 |
| kynurenic acid | 0.2595 | 0.4255 | 1.4781 | 1.8293 | 1.6067 | 0.2243 | 0.2945 | 1.5229 | 1.6677 | 1.3809 |
| kynurenine | 1.1492 | 0.8117 | 0.8333 | 1.3200 | 0.6519 | 1.2749 | 0.6525 | 0.9166 | 1.2040 | 0.7449 |
| leucine / isoleucine | 1.0682 | 0.8792 | 1.0033 | 0.9380 | 1.6364 | 1.1749 | 0.7451 | 1.1202 | 0.7938 | 1.4369 |
| lysine | 0.8728 | 0.6150 | 1.1199 | 0.8708 | 2.2137 | 0.9992 | 0.5833 | 1.2746 | 0.9929 | 2.1900 |
| melatonin | NA | NA | 0.8630 | 1.2182 | NA | NA | NA | 0.8399 | 0.9617 | NA |
| methionine | 1.2332 | 0.9153 | 1.0833 | 0.5306 | 1.0933 | 1.4418 | 0.8819 | 1.3566 | 0.4824 | 1.0875 |
| methioninesulfoxide | 0.7715 | 0.8592 | 1.3013 | 1.0255 | 0.9905 | 0.8086 | 0.9092 | 1.4503 | 0.8819 | 0.9356 |
| NAD+ | 0.8343 | 1.0307 | 0.8290 | 1.0966 | NA | 1.0441 | 0.9779 | 1.0922 | 1.0642 | NA |
| NADP+ | 0.4794 | 0.7270 | 1.6541 | 0.9917 | NA | 0.6005 | 0.6606 | 1.9777 | 1.0244 | NA |
| nicotinamide | 0.3218 | 0.4756 | 1.4141 | 1.7445 | 0.7582 | 0.3603 | 0.8475 | 1.4444 | 1.4942 | 0.7281 |
| N-trimethyllysine | 1.0730 | 0.5733 | 0.7405 | 1.5220 | 0.4224 | 1.2464 | 0.5029 | 0.9109 | 1.6865 | 0.4636 |
| ornithine | 0.9277 | 0.6227 | 1.5000 | 0.6278 | 1.2274 | 1.0771 | 0.6412 | 1.7513 | 0.7059 | 1.1619 |
| phenylalanine | 1.0623 | 0.7861 | 0.9180 | 1.0053 | 1.4023 | 1.2352 | 0.7053 | 1.1822 | 0.8976 | 1.3107 |
| phosphocholine | 1.5681 | 0.9026 | 0.6301 | 0.9499 | 0.0068 | 1.8186 | 0.8642 | 0.8541 | 0.9156 | 0.0071 |
| proline | 1.3104 | 0.9793 | 1.0184 | 0.7932 | 0.6212 | 1.4199 | 0.8524 | 1.1247 | 0.7196 | 0.5721 |
| propionyl-carnitine | 0.2591 | 0.2338 | 0.7784 | 3.2262 | 0.1417 | 0.2854 | 0.1793 | 0.6047 | 2.9010 | 0.1434 |
| riboflavin | 0.4460 | NA | 0.7129 | 0.6356 | 5.9368 | 0.4881 | NA | 0.6786 | 0.5570 | 5.0574 |
| S-adenosyl-methionine | 0.5915 | NA | 1.8137 | 0.6790 | 0.0033 | 0.7301 | NA | 1.9124 | 0.7078 | 0.0040 |
| sarcosine | NA | NA | 1.5524 | 0.4090 | NA | NA | NA | 1.6537 | 0.3795 | NA |
| serine | 0.7867 | 0.8686 | 1.4907 | 0.8122 | 1.2151 | 0.8387 | 0.7552 | 1.6423 | 0.6918 | 1.2030 |
| threonine | 1.0608 | 0.6762 | 0.8848 | 0.7507 | 2.2096 | 1.3880 | 0.6490 | 1.1371 | 0.7950 | 2.1023 |
| valine | 0.2876 | 0.2122 | 2.5549 | NA | 0.4860 | 0.2899 | 0.1786 | 2.7323 | NA | 0.4172 |
Factors:
| F1 | Genotype:AK | Tissue:brain |
| F2 | Genotype:AK | Tissue:heart |
| F3 | Genotype:AK | Tissue:liver |
| F4 | Genotype:AK | Tissue:placenta |
| F5 | Genotype:AK | Tissue:serum |
| F6 | Genotype:WT | Tissue:brain |
| F7 | Genotype:WT | Tissue:heart |
| F8 | Genotype:WT | Tissue:liver |
| F9 | Genotype:WT | Tissue:placenta |
| F10 | Genotype:WT | Tissue:serum |
