Data for (Study ST002876)

(Analysis AN004713)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Metabolite	F1	F2	F3	F4	F5	F6
1-phenylethylamine	0.5283	2.1445	0.3434	2.0343	0.5489	0.3459
2- / 3-phosphoglycerate	1.7266	1.0826	0.8742	0.7575	0.5825	0.9765
2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine	1.0207	1.0101	1.0776	0.6959	0.9254	1.2704
2-HG	0.5384	0.7786	0.7923	1.4189	1.4143	1.0575
2-hydroxybutanoic acid	1.9670	0.7342	0.6002	0.8285	0.9203	0.9499
2-keto-isovaleric acid	1.6146	1.1174	0.7674	1.0601	0.9004	0.5401
3- / 7-methylguanine	1.3713	0.8273	0.9466	1.0014	0.9645	0.8889
3-hydroxypropanoic acid	0.4857	1.0037	1.0160	1.4558	1.0047	1.0342
3-phosphohydroxypyruvic acid	1.5652	0.9122	0.2131	1.2091	1.0774	0.2824
3-ureidopropionic acid	1.4055	0.9839	1.2461	0.6547	1.1078	0.6019
4-hydroxybutanoic acid	1.6339	0.8361	0.8297	0.8856	0.9385	0.8762
4-hydroxyproline / 5-aminolevulinate	1.0783	1.0641	1.0462	0.7867	1.0026	1.0221
5-aminopentanoic acid	1.0531	1.0846	0.8463	0.8912	1.5075	0.6174
5-methylcytosine	0.8021	0.8682	1.1063	0.9172	0.9718	1.3344
5^-methylthioadenosine	0.8636	0.9799	0.8798	1.1249	1.3137	0.8380
6-aminohexanoate	1.1103	1.0797	1.2523	0.7179	1.1647	0.5126
6-phosphogluconic acid	1.1254	0.8557	0.9851	1.2285	NA	0.5076
acetoin	0.5139	0.5160	0.4439	1.5648	1.8357	1.1257
acetylcarnitine+	1.9331	1.6746	0.9256	0.4970	0.5348	0.4350
acetylcholine+	1.0835	1.1054	1.1811	0.8072	0.8940	0.9288
aconitic acid	0.1568	0.4969	0.9655	1.0818	1.5996	1.6995
adenine	0.8019	0.6984	0.6803	1.3650	1.6690	0.7854
adenosine	0.6398	0.3852	0.2820	1.5918	1.6078	1.4934
adenylosuccinate	0.0376	0.0547	NA	1.7378	1.1568	1.0621
ADP / dGDP	0.6721	0.8690	0.8387	1.1919	1.2754	1.1529
a-KG	1.6674	1.1748	0.5070	1.2840	1.1422	0.2246
alanine	1.2651	1.2868	0.8618	0.8275	1.0217	0.7370
allantoin	1.2553	1.0538	0.9471	0.8831	1.0456	0.8151
AMP / dGMP	0.3814	0.3053	0.2231	1.8571	1.6275	1.6057
anserine	1.1678	0.7140	1.4798	0.7371	0.8866	1.1231
arginine	0.8713	1.0330	0.9200	0.9623	1.1559	1.0574
asparagine	1.1125	1.2211	0.9204	0.7906	1.0300	0.9255
aspartic acid	0.8235	0.8606	1.5417	0.7410	0.8150	1.2183
ATP / dGTP	0.8390	1.5890	2.0391	0.5063	0.5234	0.5032
b-alanine	0.9247	0.8920	1.0108	0.9979	1.1510	1.0236
betaine+	1.1670	0.9848	0.9349	0.9059	1.0698	0.9375
bilirubin	1.6211	0.4604	0.7837	0.6265	0.6357	3.6179
biotin	0.8857	1.0091	0.6470	1.1710	1.3670	0.9202
butyric acid / (iso)	0.9309	1.0826	0.9635	1.1428	0.9691	0.9111
"cAMP(2^,3^) / cAMP(3^,5^)"	0.6819	0.6141	1.0897	1.0089	1.1410	1.1011
carnitine+	1.1804	1.2348	1.3028	0.6934	0.7652	0.8235
carnosine	1.5887	1.6470	0.5858	0.6832	0.6569	0.8384
CDP	0.5142	0.8530	0.8066	1.2494	1.3395	1.2373
CDP-choline+	0.8990	1.0615	0.8959	1.1682	1.1137	0.8617
choline+	0.4612	0.5037	1.3313	0.9074	0.9912	1.8052
citraconic acid	0.9393	0.9437	0.9322	1.7277	0.8253	0.6318
citramalic acid	0.5778	1.3862	0.8401	1.1759	1.0596	0.9605
citrate / citrate(iso)	0.7972	0.9769	1.0368	0.9878	1.2064	0.9949
citrulline	1.0385	1.0718	0.8592	1.0008	1.0397	0.9901
CMP	0.2980	0.2817	0.2390	1.7944	1.7672	1.6197
coenzyme A	1.0529	1.4790	0.7393	1.4705	0.5284	0.5948
creatine	1.2622	1.2127	0.9493	0.8572	0.9784	0.7402
creatinine	1.3460	1.0118	0.8957	0.9011	1.0542	0.7911
CTP	0.8231	1.4330	2.1988	0.6329	0.5113	0.4009
cystathionine	1.0164	1.2637	0.7570	0.7985	0.8023	1.3621
cysteine	0.9436	0.8714	0.8182	1.1412	1.2897	0.9360
cystine	0.9707	0.8815	0.9810	1.0714	1.1406	0.9548
cytidine	0.5748	0.1182	0.0736	1.8873	1.7242	1.6219
cytosine	1.4845	1.2581	0.8214	0.8254	0.9203	0.6903
dCMP	1.0886	1.1879	0.9877	1.0577	0.8871	0.7909
dehydroascorbic acid	1.4279	1.0942	0.1591	1.0552	1.0878	0.4229
deoxyadenosine	2.2854	1.5107	0.8139	0.2266	0.1633	NA
deoxycarnitine+	0.8903	0.9940	1.1785	0.8844	0.8470	1.2059
deoxycytidine	1.6204	1.3388	0.7723	0.7742	0.8671	0.6272
deoxyguanosine	0.8397	1.3074	0.6150	0.8270	0.9436	1.4486
deoxyinosine	1.5188	0.6355	0.3839	0.6105	1.4657	0.8450
D-galactonic acid / D-gluconic acid	0.7773	0.7546	0.6208	1.2524	1.4578	1.1371
D-galactosamine/glucosamine-1/6-phosphate	1.4700	1.0172	1.4803	0.9050	0.3650	0.3263
D-glucuronolactone / D-galacturonolactone	1.2992	1.0982	0.8801	1.0396	0.9964	0.6865
dihydroorotate	1.9105	0.7109	0.3647	1.3731	1.3725	0.2682
dimethylglycine	1.0696	1.1342	1.0110	0.9593	1.0366	0.7894
D-ribose-1/5-phosphate / D-ribulose 5-phosphate	1.3475	1.3822	1.5696	0.6318	0.5893	0.3427
D-sedoheptulose	0.6997	1.0245	1.1854	NA	0.6463	1.3492
D-sedoheptulose-7-phosphate	1.1650	1.8674	1.2404	0.7147	0.7107	0.3017
dTMP	0.7895	0.8879	0.5321	1.4355	1.4599	0.8951
epinephrine / normetanephrine	1.0439	0.9132	0.9495	0.8734	1.0285	1.1914
"F-1,6/2,6-DP"	2.3909	1.1899	1.3526	0.3135	0.2218	0.2969
F1P	0.6453	0.9811	0.9316	1.0915	1.0816	1.1443
F6P / G1P / G6P	0.7303	1.0750	1.5107	0.8315	0.8890	0.9634
FAD	0.7307	0.7667	1.0077	0.9107	1.6244	0.9300
fructose / mannose	0.5803	1.0153	0.9488	0.6964	1.1621	1.5972
fumaric acid	1.4214	0.9777	0.9369	1.1003	0.9658	0.5979
GABA	0.5932	1.4306	1.1397	0.6703	1.1346	1.0316
galactosamine / glucosamine / mannosamine	1.2530	0.9912	0.8611	0.8918	0.9376	1.0652
galactose / glucose	1.7377	0.7830	0.9167	0.7942	0.8544	0.9140
GalNAC / GlcNAC	1.1684	0.8981	1.2461	0.8831	1.0441	0.7603
GAP / DHAP	0.8887	1.3254	1.2426	1.1726	0.7659	0.6048
GDP	0.5441	0.7859	0.9402	1.1376	1.2424	1.3499
GDP-L-fucose	0.7190	0.9572	0.9829	1.2197	1.0249	1.0963
glutamate	1.0871	1.1305	0.9919	0.9427	1.0302	0.8177
glutamine	1.3219	1.5478	1.1957	0.4018	0.5478	0.9849
glutathione	0.8137	0.6135	0.6221	1.5045	1.6211	0.8250
glutathione disulfide	1.7194	0.9671	0.6483	0.7705	1.3964	0.4982
glyceric acid	1.3953	0.5984	0.5164	1.2296	1.2507	1.0096
glycerol 2/3-phosphate	0.8441	0.6422	2.9514	0.4677	0.4636	0.6309
glycine	1.0227	1.0942	0.9844	0.9204	1.0256	0.9526
GMP	0.2854	0.2526	0.2145	1.7988	1.7405	1.7082
GTP	0.5844	1.4793	2.1467	0.5737	0.5839	0.6321
guanidine	1.3380	0.9262	0.9563	0.8976	0.8691	1.0129
guanidinoacetate	2.3236	1.3292	1.8319	0.1876	0.1681	0.1596
guanine	0.6139	0.1773	0.0725	1.5773	1.8685	1.6905
guanosine	0.9536	0.5951	0.4234	1.8954	0.9653	0.8401
histidine	1.0908	1.0999	0.9316	0.8825	1.0685	0.9267
homocysteine	1.8618	1.4113	0.9037	0.7895	0.8420	0.1917
homoserine / threonine / allothreonine	1.0963	1.2972	1.0862	0.7857	0.9109	0.8237
hydroxyphenyllactic acid / HVA	1.2345	1.2202	0.7500	0.9141	1.1036	0.7776
hydroxypyruvic acid	1.1345	0.6970	0.9263	1.0230	1.1271	1.0922
hypoxanthine	0.4973	0.1656	0.0885	1.9547	2.2017	1.0923
imidazole-4-acetate	0.9973	0.9568	0.9977	0.9670	0.8952	1.1861
IMP	0.7011	0.5264	0.4251	2.0943	1.7170	0.5362
inosine	0.6326	0.1735	0.1092	1.8854	1.8860	1.3132
kynurenine	1.2694	1.0964	0.7977	0.8769	1.1265	0.8331
lactic acid	1.4364	0.7561	0.7956	1.3673	0.9202	0.7243
L-arginino-succinate	1.0617	1.0026	0.7988	1.1770	1.1909	0.7691
L-cysteic acid	0.7965	0.9530	0.8246	1.6851	0.8127	0.9125
leucine / leucine(iso) / norleucine	1.2172	1.1092	0.9164	0.8368	1.0049	0.9155
L-NMMA	0.6306	1.0445	0.9784	0.7970	1.3391	1.2103
lysine	0.7434	0.9263	1.2077	0.8448	1.0592	1.2186
maleic acid	1.7375	0.8508	0.7471	1.0522	0.7646	0.8478
malic acid	1.0975	0.6576	0.7688	1.5128	1.2987	0.6646
malonic acid	1.0887	0.9255	0.9357	1.0094	0.9906	1.0500
ManNAC	0.4742	0.2970	0.9791	0.9610	1.6813	1.4321
mesaconic acid	0.4544	0.6997	0.8884	1.1290	1.4114	1.4171
methionine	1.1480	1.1346	0.9958	0.7921	0.9591	0.9704
methylmalonic acid	0.8566	1.3324	0.7469	0.5186	0.6978	1.8476
N1-acetylspermine	1.3282	0.9943	0.7774	0.7374	0.9897	1.1730
N1/N8-acetylspermidine	0.1550	0.2680	0.7964	1.4348	1.4524	1.8935
N-acetylaspartic acid	0.8530	1.2110	2.1994	0.3963	0.4565	0.8837
N-acetyl-b-alanine / N-acetyl-alanine	1.0698	1.0173	0.9555	0.9903	1.1332	0.8339
N-acetyl-DL-serine / O-acetyl-L-serine	0.9626	0.9889	0.9890	0.9712	1.1349	0.9534
N-acetylglucosamine 1/6-phosphate	0.6549	1.0147	1.4371	0.9263	0.9325	1.0345
N-acetyl-L-glutamic acid	0.9292	1.1262	1.0074	0.9304	1.0544	0.9524
NAD+	0.4791	0.4730	0.5491	1.7227	1.5877	1.1884
N-carbamoyl-L-aspartate	2.2707	0.7635	0.3380	1.0801	0.5476	NA
N-formyl-L-methionine	0.9674	1.0651	0.9849	0.8905	1.0925	0.9996
nicotinamide	1.6334	1.4577	1.4268	0.4388	0.4642	0.5790
nicotinamide riboside+	0.9135	0.6041	0.8856	1.2488	0.9716	1.3764
N-methylaspartic acid	1.1524	1.1536	1.0108	0.9394	0.9697	0.7741
norepinephrine / pyridoxine	1.3703	1.1022	0.8230	0.9304	1.0034	0.7709
ornithine	0.7322	0.8601	1.5708	0.5095	0.9723	1.3550
orotic acid	1.3203	1.0178	0.5623	1.1941	1.4836	0.4219
O-succinyl-homoserine	0.7713	NA	1.1293	0.8505	1.2589	NA
pantothenic acid	1.1416	1.1722	0.8161	0.9944	1.1315	0.7443
phenethylamine	0.6078	0.5991	1.2386	1.0431	1.2917	1.1685
phenylalanine	1.1832	1.1253	0.9492	0.8164	0.9876	0.9382
phenylephrine / synephrine	0.7394	1.1843	0.7460	1.0057	1.1148	1.2098
phosphocreatine	0.7712	1.2366	1.1797	0.9770	0.9798	0.8558
phosphorylcholine+	0.7620	0.8960	0.8765	1.1579	1.2151	1.0925
proline	0.9524	0.7970	0.6523	1.2183	1.3453	1.0347
pseudouridine	1.2877	0.9502	0.9170	0.7821	1.0664	0.9690
putrescine	0.8430	1.3309	1.4055	0.7305	0.9053	0.7848
pyridoxal	1.2345	1.0008	0.9167	0.9512	0.9816	0.9152
pyroglutamic acid	1.2120	1.1145	0.9734	0.9818	0.9640	0.7544
pyrroline hydroxycarboxylic acid	1.2064	1.2617	1.0576	0.8003	0.8467	0.8273
pyruvic acid	1.0521	0.9074	0.9661	1.2251	1.1487	0.7006
S-adenosyl-L-homocysteine	1.1467	1.1706	0.8251	1.2258	1.0146	0.6172
S-adenosyl-L-methionine+	0.9797	1.2021	0.9520	0.9849	1.1582	0.7232
sarcosine	0.0010	NA	NA	0.0036	2.8077	1.4573
serine	0.9093	1.2177	1.5700	0.6149	0.6039	1.0842
serotonin	1.2404	1.1717	0.9552	0.7841	0.9747	0.8739
sorbitol / galactitol / L-iditol / manitol	1.4046	0.8330	0.9940	0.7426	0.8308	1.1949
spermidine	1.9992	1.8825	0.9370	0.4245	0.3681	0.3888
spermine	1.0306	1.0455	1.0148	1.0051	0.9383	0.9657
succinic acid	1.0296	0.6224	0.6003	1.4681	1.2706	1.0090
taurine	1.0059	0.9657	1.1442	0.8946	1.0093	0.9803
thiamine+	2.0372	1.5731	0.7594	0.5957	0.5418	0.4929
thiamine diphosphate+	1.6939	1.9766	0.9310	0.6046	0.5702	0.2238
thiamine phosphate+	1.1784	1.2497	0.8751	0.9814	0.8451	0.8703
thymidine	2.0699	1.5133	0.8496	0.4777	0.6612	0.4329
thymine	0.7599	0.5671	NA	1.4649	0.7766	1.4239
tryptamine	1.3976	1.0350	0.4416	NA	0.4926	1.2477
tryptophan	1.1610	1.0644	0.9138	0.8338	1.0475	0.9796
tyrosine	1.2442	1.1596	0.8838	0.8681	0.9704	0.8739
UDP	0.6000	0.7587	0.6708	1.4157	1.4365	1.1183
UDP-D-galactose / UDP-D-glucose	0.7774	1.0293	1.0117	1.0674	1.1781	0.9361
UDP-N-acetyl-galactosamine/UDP-N-acetyl-glucosamine	0.8188	1.0404	1.2124	1.0424	0.9485	0.9376
UMP	0.2647	0.2082	0.1352	1.9889	1.8332	1.5698
uracil	1.0340	0.9532	0.7929	0.9861	1.4131	0.8207
uric acid	2.8175	0.6669	0.6907	0.5156	0.6491	0.6602
uridine	0.8796	0.3859	0.2832	1.5862	1.6047	1.2604
UTP	0.9271	1.6083	2.0515	0.4436	0.5247	0.4448
valine / norvaline	1.1582	1.1200	1.0440	0.8011	0.9379	0.9386
vitamin B2	0.7288	0.5246	NA	1.1748	1.2670	1.0140
xanthine	1.3446	0.9979	0.8979	0.9536	1.0346	0.7715
XMP	0.4610	0.6756	0.8166	1.5918	1.3436	1.1115
xylitol / arabitol / ribito	0.8994	0.9617	1.0605	1.0414	1.0963	0.9407
y-glutamylcysteine	0.7040	0.6778	0.8485	1.3486	1.3320	1.0892

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1	Genotype:High NSD2 | Treatment:Control
F2	Genotype:High NSD2 | Treatment:Knockdown 1
F3	Genotype:High NSD2 | Treatment:Knockdown 2
F4	Genotype:Low NSD2 | Treatment:Control
F5	Genotype:Low NSD2 | Treatment:Knockdown 1
F6	Genotype:Low NSD2 | Treatment:Knockdown 2