Data for (Study ST002878)

(Analysis AN004716)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8F9F10F11F12
3-methyl-2-oxobutyrate 1.0276 1.7627 1.7158 0.8238 1.0636 1.6421 0.7223 0.9554 1.0200 0.6974 1.0152 0.8665
4-aminobutyrate 0.2501 0.3475 0.2023 0.2182 0.2742 0.3922 1.5657 1.3032 1.2839 1.4351 1.2439 1.2499
6-phosphogluconic acid 0.7742 1.0807 0.9337 0.8914 1.1227 1.6924 1.0587 0.9696 1.0481 0.8364 1.0656 0.8051
acetyl-CoA 1.9257 0.8377 0.6627 1.0190 1.1971 0.8484 1.4281 1.1970 0.8910 0.7869 0.6945 1.0644
adenylosuccinic acid 0.6792 0.3515 0.2998 0.3180 0.4686 1.0260 1.1912 3.6734 0.8562 0.5169 0.7690 0.6821
ADP 0.5427 0.7689 0.6892 0.7789 0.7094 0.8908 1.0038 1.3576 1.1235 1.0080 1.1658 1.0649
AICAR 2.3672 1.4042 1.1536 1.7427 0.3721 0.0504 1.7668 0.8534 0.7885 0.6559 0.6208 0.7695
alpha-ketoglutarate 0.9383 1.2795 0.8992 1.2467 0.7386 0.7145 1.2975 1.0000 0.9352 0.9894 0.8636 0.9825
AMP 1.1788 0.8694 0.8470 0.8534 1.0455 1.2258 1.1769 1.2161 0.9612 0.8092 0.9816 0.8615
anthranilic acid NA 0.4802 0.4935 0.3841 0.6680 0.5140 0.9898 1.1684 1.0402 0.9771 1.2397 1.1998
arachidic acid 1.4795 1.3900 1.7282 1.1328 1.2059 1.3232 0.8275 0.9257 0.9052 0.6894 0.8216 0.8300
argininosuccinate NA NA NA NA NA NA 1.2277 1.0369 0.7763 1.1066 0.8395 1.0131
ascorbate 0.6494 0.4495 0.4282 0.4875 0.4633 0.6596 1.2675 1.2326 1.1680 1.1714 1.2973 1.2519
aspartate 1.1183 1.4711 0.9196 1.1030 1.4315 1.3199 1.3424 0.9746 0.7595 0.9846 0.6818 0.6597
ATP 0.7435 0.8757 0.6991 1.0245 0.5897 0.8166 0.8739 0.9762 1.2395 0.8845 1.2082 1.2087
butyric acid 0.9849 1.0315 0.9574 0.8299 0.9707 1.0397 1.0006 0.9450 1.0968 0.9970 1.0780 0.9944
caproic acid 1.2484 1.2178 1.0518 0.9832 1.3559 1.0148 0.9043 0.9088 0.9110 0.9936 0.9842 0.9064
carbamoyl-aspartate 0.0856 0.1077 0.1113 0.1201 0.1470 0.1338 2.4194 1.4311 1.0325 1.8650 1.2808 0.7965
CDP 0.6553 0.5650 0.4257 0.5839 0.3500 0.4349 1.3773 1.5727 1.1784 1.1408 0.8734 0.7901
CDP-ethanolamine 0.7408 1.2272 0.8766 0.9431 0.6949 0.7910 0.9611 1.1002 0.9632 1.0082 1.0698 1.1287
cholic acid 3.3158 2.1187 1.6844 1.9873 1.1458 0.8056 0.6656 0.3805 0.3227 0.4502 0.3743 0.4187
cis-aconitate 0.8071 0.9489 0.9164 0.9695 0.9673 0.9466 1.0625 1.0331 0.9654 1.1260 0.9876 1.0226
citrate / isocitrate 0.9304 1.0536 1.0708 1.0955 1.1049 1.0857 0.9675 0.9662 0.9600 1.0218 0.9300 1.0054
CMP 2.0014 1.4223 1.1561 1.4295 1.0981 0.9742 0.8684 1.3632 0.6909 1.1217 0.6546 0.6508
CoA 0.2864 0.1956 0.1948 0.2077 0.5766 0.8212 1.1398 1.1539 1.1152 0.9398 1.5166 1.4390
CTP 0.8406 0.7681 0.5325 0.8151 0.3815 0.4390 1.3707 0.9998 1.3329 1.0323 1.1290 1.0667
cysteine 0.2299 1.3659 1.1328 0.4670 1.4701 0.2236 0.2810 1.4089 0.9192 1.7490 0.6959 1.6644
cystine 1.4114 3.5425 0.6198 1.2789 4.6038 0.1774 0.1227 0.1221 0.1236 0.1477 0.1067 0.0754
cytidine 0.9596 0.6521 0.6244 0.5230 0.6173 0.6376 1.4860 1.1858 1.0083 1.0260 1.0997 1.0063
deoxycholic acid 4.6678 1.4308 0.9664 1.7977 0.6157 0.5420 0.8917 0.3362 0.2038 0.3913 0.2265 0.2353
deoxyinosine 2.0454 1.3053 0.8973 1.3487 0.4718 0.4159 1.7845 1.1415 0.7227 1.1947 0.5041 0.5313
dihydroorotate 0.1195 NA NA 0.2715 0.1873 NA 1.2826 1.4054 0.9187 1.9789 0.7948 0.5239
dihydroxyacetone-phosphate 0.3332 0.6000 0.6100 0.5543 0.5882 0.6321 0.6298 1.2849 1.4436 0.8178 1.5443 1.4292
dTMP 1.0493 1.0971 0.6927 0.8334 0.3411 0.4249 1.9958 1.4358 0.6299 1.2529 0.6461 0.4298
dTTP 1.2250 1.3813 0.9460 1.8112 0.4227 0.4896 1.1818 1.2008 1.0376 1.2201 0.8027 0.5552
erythrose-4-phosphate 0.8313 1.1404 1.1877 1.2462 1.1248 1.3144 0.8722 0.9658 0.9505 1.0707 0.9695 0.9601
fructose 0.5449 0.5616 0.6473 0.5186 1.0192 1.1554 1.2040 0.8856 1.0033 1.4905 0.9767 1.0223
fructose-1;6-bisphosphate 1.0852 0.9588 0.8959 0.8733 0.9828 0.7943 1.3370 1.8733 0.8725 0.8491 0.6927 0.5496
fructose-1-phosphate 1.8126 1.2869 1.4823 1.4694 1.5602 1.9900 0.9171 0.6535 0.6557 0.7334 0.5637 0.6760
fructose-6-phosphate 0.7747 0.8992 0.9928 0.9241 1.0070 1.3169 0.9670 0.8765 1.0351 0.9955 1.0624 1.1033
fumarate 0.7784 0.9016 0.8511 0.9783 0.8322 0.9406 1.1211 1.0471 1.1124 1.0378 1.0185 0.9502
GAR 1.1058 1.1343 1.1092 1.2128 1.0825 1.1809 0.8917 0.9606 0.9364 0.8924 1.0297 1.0828
GDP 0.5994 0.7221 0.6144 0.7111 0.6398 0.7459 1.1047 1.4145 1.1281 1.0300 1.1129 1.0823
glucose 0.8020 1.2437 2.0699 1.1518 2.2639 1.9280 0.4423 0.8669 0.8518 0.7739 0.7672 0.7877
glucose-6-phosphate 0.5418 0.8496 0.9594 0.8499 1.0242 1.1756 0.7391 0.9751 1.0719 0.9888 1.1563 1.2561
glutamate 0.8559 0.6790 0.5675 0.6696 0.4981 0.5018 1.6962 1.1510 1.0609 1.2115 0.9663 0.8918
glutamine 0.9206 1.1268 1.4210 1.2213 1.2957 1.2842 0.9045 0.9724 0.8550 0.9874 0.8649 0.8589
glyceraldehyde-3-phosphate 1.1012 1.0532 0.8699 0.8775 0.8716 0.3624 1.5190 2.2000 0.7138 1.0041 0.5734 0.4219
glycerol-3-phosphate 0.4164 0.5959 0.5694 0.4227 0.7030 0.7447 1.0724 0.9300 1.5409 0.7635 1.5310 1.2995
GMP 2.1699 1.4326 1.3488 1.6482 1.3986 1.5084 0.7943 1.0531 0.6435 0.9553 0.6936 0.7645
GSH 0.2945 0.0820 0.0758 0.1168 0.3628 0.4416 1.6490 1.0308 1.2076 0.9836 1.6613 1.5430
GSSG 0.8033 0.9413 0.8228 0.9541 0.6708 0.6255 1.1418 1.2166 1.0795 1.1744 1.0210 0.8799
GTP 0.9114 1.0363 0.9902 1.0607 0.8535 0.7962 1.0729 0.9234 1.0710 0.8537 1.0597 1.1746
guanosine 2.3383 1.0926 0.7097 1.2084 0.8659 0.9395 1.4889 0.9589 0.8072 0.8018 0.7347 0.8478
histidine 0.3579 0.6989 0.9595 0.6222 1.0254 1.0690 0.5406 1.2247 1.0584 1.1133 1.2486 1.3880
hydroxyglutarate 0.8659 0.7751 0.6862 0.8318 0.6023 0.6978 1.5080 1.0971 0.9892 1.1331 0.9421 0.8893
hypotaurine 0.4456 1.3833 1.3123 1.2880 1.6335 1.6954 0.4098 0.8738 0.8481 0.9342 0.9828 1.0188
IMP 0.9674 0.5075 0.5334 0.4957 0.3944 0.7295 1.1449 1.2962 0.5703 2.5799 0.5839 0.5660
lactate 0.5001 0.9342 1.1214 0.8887 1.2550 1.4826 0.5191 1.0199 0.9769 0.9015 1.1994 1.3254
lauric acid 0.8847 1.0359 1.1729 0.8778 1.1248 1.0991 1.0236 1.0576 0.9987 0.8554 0.9211 1.0608
malate 0.6985 0.9190 0.8389 0.9565 0.8514 0.9349 1.1222 1.0605 1.1233 1.0420 1.0427 0.9663
myristic acid 0.9384 1.5807 1.6138 1.3026 1.4336 1.8223 0.9286 0.7891 0.7875 0.7258 0.7388 0.8602
N-acetylglucosamine-phosphate 0.8260 0.7949 0.9415 0.7524 1.2236 1.2103 0.8522 0.9416 1.0389 0.8021 1.1590 1.2899
N-acetylglutamate 0.5043 0.3231 0.9728 0.2191 1.4106 1.6430 1.0845 0.9281 1.1225 0.7960 1.1776 1.3408
NADH 0.4368 0.3598 0.4148 0.3453 0.4849 0.6221 1.0547 1.1507 1.2079 1.0457 1.1639 1.2195
NADPH 0.4568 0.4234 0.3891 0.7159 0.3086 0.3922 1.3750 1.0337 1.3442 1.0323 1.0644 0.9689
oleic acid 1.6440 1.6469 1.3489 1.2913 1.4426 1.5866 0.6992 0.8142 0.8854 0.7499 0.8890 0.6595
orotate 1.4916 0.6507 0.6677 0.9386 0.4795 0.0585 1.5500 1.1097 1.0290 1.0118 0.8271 0.8343
palmitic acid 1.3897 1.3442 1.5179 1.2074 1.2739 1.2722 0.8600 0.8874 0.8838 0.8246 0.8615 0.7938
phosphate 0.7431 0.7854 0.7844 0.7355 0.7420 0.6260 1.1373 1.1861 1.0721 1.1849 1.1201 1.1371
phosphatidylethanolamine NA NA NA NA NA NA 1.0860 1.4002 1.1030 0.6355 1.0766 0.5098
phosphocreatine 1.0098 0.7768 0.5658 0.9012 0.3658 0.3643 1.6955 0.9465 1.0781 1.1767 0.8843 0.8909
phosphoenolpyruvate 1.1824 2.3509 1.7642 1.7537 1.5363 0.5666 0.7271 0.9711 0.7373 1.0043 0.5362 0.4535
phosphoglycerate 1.1358 0.6327 0.5159 0.7656 0.4682 0.5364 1.3249 1.1104 1.2403 1.0233 1.1418 1.0122
phosphorylethanolamine 0.7490 0.6445 0.6465 0.6745 0.6407 0.6910 1.2604 1.1644 1.1271 1.0756 1.1208 1.1372
phosphoserine 2.2015 0.7276 0.1970 1.9118 0.0284 0.2457 2.8437 0.7814 0.6693 0.9213 0.4695 0.4868
propionic acid 0.8628 0.9607 1.2242 0.9424 1.5770 1.4458 0.7340 0.9519 0.9823 0.8027 0.8630 1.0178
pyruvate 0.8555 1.1382 1.2235 1.0727 1.2779 1.4690 0.5993 0.9291 0.9176 0.8632 1.0059 1.2420
quinolinic acid 0.3969 0.3976 0.3698 0.4064 0.3684 0.4040 1.4925 1.3563 1.3199 1.4144 1.2527 1.2113
rib/ribul/xylul-ose-phosphate 1.5536 1.5670 0.9900 1.2162 1.2647 1.6589 1.1051 0.7827 0.7922 0.8028 0.8137 0.8034
saccharopine 0.0328 NA NA NA 0.0400 NA 2.3937 1.6280 1.1538 0.2576 1.3957 0.4875
S-adenosyl-homocysteine 0.3279 0.3388 0.3722 0.2633 0.3609 0.5372 1.1175 1.1030 0.8537 1.0995 1.2316 1.5599
SAICAR NA NA NA NA NA NA 0.8877 1.0173 0.9551 0.9610 0.9725 1.2065
sedoheptulose-7-phosphate 0.3468 0.8200 1.0332 0.7997 1.3018 1.5607 0.5298 0.9593 0.9338 0.9650 1.2185 1.4366
sorbitol 0.5496 0.9816 1.2955 0.8863 1.8015 2.4977 0.4672 0.6896 0.9271 0.6134 1.1680 1.3042
stearic acid 1.2220 1.1872 1.3151 1.0400 1.0503 1.0928 0.8427 1.0823 0.9143 0.8089 0.9348 1.0133
succinate 0.8466 0.7046 0.6103 0.6931 0.7388 1.0406 1.2456 1.0835 1.1343 0.9601 1.1433 1.0500
taurine 0.6647 0.6350 0.6002 0.6649 0.5961 0.6755 1.1826 1.1610 1.1446 1.1188 1.1868 1.1635
taurocholic acid 1.6023 1.0941 0.9858 1.4395 0.7580 0.7988 1.3514 0.9919 0.6889 1.2935 0.6108 0.6509
thymidine 0.8893 0.9479 0.7880 0.9396 0.5469 0.4261 1.1714 1.6665 0.8932 1.7350 0.6220 0.5387
thymine 0.8486 0.9659 0.8217 1.0521 0.5452 0.4431 1.1180 1.6585 0.8541 1.7017 0.6400 0.5954
trifluoromethanesulfonate 1.5240 1.3444 1.5866 1.4271 1.4484 1.1479 0.7729 0.8907 0.7493 0.8545 0.7623 0.8625
tryptophan 1.2816 0.8052 0.7637 0.9948 0.7338 0.7944 1.2719 1.0566 0.8387 1.2023 0.9514 0.9508
tyrosine 0.6067 0.7648 0.8591 0.7614 0.8754 0.9506 0.8384 1.1555 0.9194 1.2733 1.1624 1.1804
UDP 0.8272 0.7209 0.5461 0.8451 0.4731 0.6246 1.2590 1.4458 1.0807 1.0386 0.9568 0.8326
UDP-glucuronic acid 1.0257 0.8373 0.4584 0.7983 0.3021 0.4513 1.6391 1.0698 1.1667 1.0479 0.9210 0.8201
UDP-N-acetylglucosamine 0.5208 0.3758 0.3119 0.3973 0.2872 0.3736 1.4365 1.2744 1.1639 1.2602 1.1481 1.0478
UMP 1.1148 0.6872 0.4895 0.6510 0.4238 0.5864 1.6211 1.5717 0.9155 1.3764 0.6935 0.5709
uracil 0.8416 0.6028 0.6995 0.7373 0.9397 1.3446 0.8605 1.0582 0.7953 1.0061 1.2721 1.4006
uric acid 0.2256 0.1891 0.3520 0.1485 0.2508 0.2285 1.1830 1.2126 1.0435 1.1114 1.5480 1.5872
uridine 0.9975 0.4980 0.4679 0.6180 0.7601 0.9566 1.6266 1.1265 0.9018 1.0635 1.0440 0.9244
UTP 0.7751 0.8389 0.5637 0.8742 0.4046 0.4825 1.3780 1.0661 1.2779 1.2700 1.0217 0.9665
valeric acid isomers 1.2894 1.8829 1.8863 2.2702 1.8001 1.3486 0.8206 0.6030 0.5389 0.6970 0.7263 0.6168
xanthine 1.2430 0.4433 0.4430 0.7262 0.7346 1.1975 1.9537 0.9961 0.9025 1.0070 1.0385 0.9678
xylonic acid 0.6462 0.7215 1.0004 0.6087 1.3643 1.5377 0.8780 0.9796 0.8474 0.8848 1.1535 1.4150
xylulose 0.6555 0.7495 1.0487 0.8591 1.0559 1.1611 0.9349 0.9634 1.0133 0.9739 1.0563 1.2638
Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1Genotype:Akita | U13C Glucose Labelling Timepoint:0 minutes
F2Genotype:Akita | U13C Glucose Labelling Timepoint:1 hour
F3Genotype:Akita | U13C Glucose Labelling Timepoint:2 hours
F4Genotype:Akita | U13C Glucose Labelling Timepoint:30 minutes
F5Genotype:Akita | U13C Glucose Labelling Timepoint:3 hours
F6Genotype:Akita | U13C Glucose Labelling Timepoint:4 hours
F7Genotype:Wild Type | U13C Glucose Labelling Timepoint:0 minutes
F8Genotype:Wild Type | U13C Glucose Labelling Timepoint:1 hour
F9Genotype:Wild Type | U13C Glucose Labelling Timepoint:2 hours
F10Genotype:Wild Type | U13C Glucose Labelling Timepoint:30 minutes
F11Genotype:Wild Type | U13C Glucose Labelling Timepoint:3 hours
F12Genotype:Wild Type | U13C Glucose Labelling Timepoint:4 hours
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