Data for (Study ST002906)
(Analysis AN004769)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 |
---|---|---|---|---|---|
3-methyl-2-oxopentanoic acid | 0.8372 | 1.1696 | 1.2184 | 0.8113 | 0.9635 |
3-phosphoglycerate | 0.8483 | 1.1565 | 1.0322 | 0.8980 | 1.0650 |
4-Hydroxyphenylpyruvic acid | 0.9341 | 1.1047 | 1.1419 | 0.9457 | 0.8735 |
6-phosphogluconate | 0.9043 | 1.0896 | 1.1548 | 0.9078 | 0.9434 |
acetylcarnitine | 1.0141 | 1.0337 | 0.9076 | 1.0405 | 1.0041 |
Acetyl-CoA | 0.9140 | 1.1084 | 1.0508 | 0.9400 | 0.9867 |
ADP | 0.9827 | 0.9824 | 1.3137 | 0.7912 | 0.9301 |
ADP-ribose | 0.8134 | 1.0877 | 0.7043 | 1.2296 | 1.1650 |
AICAR | 1.5988 | 0.7877 | 0.0810 | 1.3372 | 1.1953 |
alanine | 0.9741 | 1.0204 | 0.9388 | 1.0710 | 0.9956 |
alanine-13C3-15N | 1.0841 | 0.8849 | 0.9666 | 1.0916 | 0.9728 |
Alpha-Ketoglutarate | 0.7832 | 1.2015 | 1.2790 | 0.8065 | 0.9298 |
alpha-keto-isovalerate | 0.8801 | 1.1668 | 1.2762 | 0.7597 | 0.9172 |
Alpha-Lipoic Acid | 1.0383 | 0.9189 | 1.0189 | 1.0612 | 0.9627 |
AMP | 0.9645 | 1.1556 | 0.9869 | 0.9127 | 0.9802 |
arginine | 1.0808 | 0.9642 | 0.8672 | 1.0710 | 1.0168 |
arginine-13C6-15N4 | 1.0642 | 0.8685 | 0.9876 | 1.0810 | 0.9987 |
argininosuccinate | 0.9516 | 0.9878 | 1.1041 | 0.9931 | 0.9633 |
ascorbate | 1.0769 | 0.9583 | 0.8778 | 1.1631 | 0.9239 |
asparagine | 1.0483 | 0.9865 | 0.8846 | 1.0635 | 1.0171 |
aspartate | 1.1010 | 0.9638 | 0.9233 | 1.0310 | 0.9809 |
aspartate-13C6-15N4 | 1.0275 | 0.8808 | 1.1025 | 1.0225 | 0.9667 |
asymmetric dimethylarginine | 1.0429 | 1.0067 | 0.9015 | 1.0356 | 1.0132 |
ATP | 0.9779 | 1.0011 | 1.2610 | 0.8208 | 0.9393 |
beta-alanine | 0.9452 | 1.0140 | 1.0283 | 1.0091 | 1.0035 |
betaine | 1.0790 | 0.9788 | 0.8585 | 1.0928 | 0.9909 |
Butyrylcarnitine | 0.9122 | 1.1028 | 1.0222 | 0.9978 | 0.9650 |
C5-Carnitines | 0.9838 | 1.0412 | 0.9599 | 1.0365 | 0.9786 |
cAMP | 0.9883 | 1.0220 | 0.9876 | 0.9585 | 1.0436 |
carnitine | 0.9604 | 1.0804 | 1.0033 | 1.0014 | 0.9545 |
CDP | 0.9869 | 1.0383 | 0.9352 | 1.0145 | 1.0251 |
CDP-choline | 1.1409 | 0.9183 | 0.9710 | 1.0262 | 0.9437 |
cis-aconitate | 0.9973 | 1.0228 | 0.9991 | 1.0153 | 0.9655 |
citrate | 1.0112 | 0.9925 | 0.9511 | 1.0272 | 1.0181 |
citrulline | 0.9858 | 0.9520 | 1.0976 | 1.0303 | 0.9342 |
CMP | 0.9486 | 1.0912 | 0.9104 | 0.9872 | 1.0626 |
Coenzyme-A | 0.9196 | 1.1146 | 1.0066 | 0.9713 | 0.9879 |
creatine | 1.0048 | 1.0052 | 0.8980 | 1.0968 | 0.9952 |
creatinine | 0.8492 | 1.4658 | 0.8133 | 0.9610 | 0.9108 |
CREATININE N-METHYL-D3 | 1.0360 | 0.9006 | 1.0153 | 1.0272 | 1.0209 |
CTP | 1.1047 | 0.9755 | 0.9695 | 0.9294 | 1.0208 |
cystathionine | 0.9946 | 1.0569 | 0.7960 | 1.0612 | 1.0913 |
cystine | 1.3189 | 0.7221 | 0.9701 | 0.9689 | 1.0199 |
cystine-13C6-15N2 | 1.2652 | 0.6721 | 1.0824 | 1.0622 | 0.9181 |
cytidine | 0.6206 | 1.0272 | 1.8366 | 0.7666 | 0.7490 |
dATP | 0.8522 | 1.0907 | 1.3353 | 0.7989 | 0.9229 |
dCTP | 0.9424 | 1.0310 | 1.3172 | 0.7828 | 0.9265 |
dCytidine | 0.8366 | 1.0432 | 1.2167 | 0.9719 | 0.9316 |
dihydroxyacetone phosphate | 0.6956 | 1.0488 | 1.3583 | 0.7060 | 1.1913 |
dTMP | 0.6930 | 1.2358 | 1.1807 | 0.8645 | 1.0260 |
dTTP | 1.0687 | 1.0808 | 0.9825 | 0.8795 | 0.9885 |
dUMP | 1.3835 | 0.6912 | 0.1629 | 1.0765 | 1.1278 |
erythrose-4-phosphate | 1.0933 | 0.9634 | 0.9504 | 0.9950 | 0.9979 |
F6P G1P | 1.0951 | 1.0406 | 0.8786 | 0.9912 | 0.9944 |
FAD | 1.0009 | 1.0360 | 1.0401 | 0.9653 | 0.9578 |
formyl-methionine | 0.9345 | 1.1193 | 1.0120 | 0.9689 | 0.9653 |
Fructose-1,6-bisphosphate | 0.8024 | 1.1325 | 1.1762 | 0.9563 | 0.9325 |
fumarate | 0.8768 | 1.0146 | 1.1764 | 0.9683 | 0.9639 |
GAR | 2.0097 | 0.4977 | 0.1596 | 1.3371 | 0.9959 |
GDP | 0.9514 | 1.0417 | 1.1224 | 0.9371 | 0.9475 |
Glucose-6-phosphate | 1.0826 | 0.9737 | 0.9822 | 0.9984 | 0.9632 |
glutamate | 1.0168 | 0.9917 | 0.9369 | 1.0472 | 1.0073 |
glutamate-13C5-15N | 1.0775 | 0.8893 | 1.0193 | 1.0486 | 0.9652 |
glutamine | 1.0902 | 0.9373 | 0.9063 | 1.0527 | 1.0135 |
glyceraldehyde-3-phosphate | 0.6858 | 1.1973 | 1.3117 | 0.8470 | 0.9581 |
glycerate | 1.0489 | 0.9217 | 0.9996 | 1.0290 | 1.0009 |
Glycerol-3-Phosphate | 0.7534 | 1.0240 | 1.4155 | 0.9086 | 0.8986 |
Glycerophosphocholine | 0.7213 | 0.9916 | 1.6027 | 0.8667 | 0.8177 |
glycine | 0.7851 | 1.0066 | 1.4381 | 0.8892 | 0.8810 |
GMP | 1.0628 | 1.0592 | 1.1877 | 0.7532 | 0.9370 |
GSH | 0.9762 | 1.0197 | 1.0978 | 0.9090 | 0.9973 |
GSSG | 1.0151 | 1.0251 | 0.7355 | 1.2163 | 1.0080 |
GSSG-13C4-15N2 | 1.1234 | 0.8360 | 0.9150 | 1.0812 | 1.0444 |
GTP | 1.0110 | 1.0045 | 1.1616 | 0.8682 | 0.9547 |
guanine | 0.7864 | 0.9716 | 1.4548 | 0.9208 | 0.8663 |
guanosine | 0.7818 | 0.9091 | 1.6955 | 0.9424 | 0.6712 |
histidine | 1.2243 | 0.9305 | 0.6747 | 1.0896 | 1.0808 |
histidine-13C6-15N3 | 1.2416 | 0.8305 | 0.7509 | 1.1502 | 1.0268 |
hydroxyglutarate | 1.0051 | 0.8726 | 1.1098 | 0.9258 | 1.0867 |
hydroxyproline gammaALA | 1.0812 | 1.0167 | 0.8502 | 1.0158 | 1.0361 |
hypotaurine | 0.9513 | 1.0435 | 1.0489 | 0.9589 | 0.9975 |
hypoxanthine | 1.1518 | 1.3701 | 0.8114 | 0.6555 | 1.0112 |
HYPOXANTHINE-13C5 | 1.0434 | 0.8621 | 1.0111 | 1.0174 | 1.0660 |
IMP | 1.0966 | 1.1278 | 0.4909 | 1.0960 | 1.1888 |
indolelactate | 1.1059 | 0.8584 | 0.8795 | 1.0682 | 1.0880 |
inosine | 0.4816 | 1.4318 | 1.6706 | 0.3403 | 1.1135 |
isocitrate | 1.0112 | 0.9920 | 0.9517 | 1.0270 | 1.0181 |
isoleucine | 1.0627 | 1.0228 | 0.8834 | 0.9999 | 1.0313 |
Isoleucine-13C6-15N | 1.0732 | 0.8716 | 0.9556 | 1.0541 | 1.0454 |
Itaconic acid | 1.0779 | 0.9307 | 0.9981 | 1.0174 | 0.9759 |
kynurenine | 1.0435 | 1.0277 | 0.8748 | 0.9816 | 1.0725 |
lactic acid | 0.7419 | 1.1568 | 1.3348 | 0.8848 | 0.8817 |
L-ALANINE-13C3 | 1.1004 | 0.8953 | 0.9496 | 1.1051 | 0.9496 |
leucine | 1.0775 | 0.9841 | 0.8740 | 1.0132 | 1.0512 |
leucine-13C6-15N | 1.0724 | 0.8726 | 0.9463 | 1.0209 | 1.0878 |
L-PHENYLALANINE RING-13C6 | 0.9848 | 1.0235 | 0.9351 | 1.5655 | 0.4911 |
L-TRYPTOPHAN-13C11 | 1.0526 | 0.9093 | 0.9465 | 1.0352 | 1.0565 |
L-TYROSINE RING-13C6 | 1.0122 | 0.6697 | 1.0674 | 1.1012 | 1.1495 |
lysine | 1.2447 | 0.9423 | 0.6514 | 1.1027 | 1.0589 |
lysine-13C6-15N2 | 1.1397 | 0.9080 | 0.7607 | 1.1280 | 1.0636 |
malate | 0.8659 | 1.0158 | 1.1727 | 0.9839 | 0.9617 |
malonyl-CoA | 0.8166 | 1.1581 | 1.1498 | 0.9747 | 0.9009 |
Methioninesulfoxide | 1.1447 | 0.8440 | 0.7325 | 1.0857 | 1.1931 |
methylnicotinamide | 0.9661 | 1.0067 | 1.1080 | 0.9661 | 0.9530 |
methylthioadenosine | 0.9690 | 1.0262 | 0.9636 | 0.9415 | 1.0996 |
myo-inositol | 0.9960 | 1.0449 | 0.9724 | 1.0226 | 0.9641 |
N-acetylcysteine | 0.8928 | 1.1775 | 1.0061 | 0.8934 | 1.0303 |
N-acetylglutamate | 0.9402 | 0.9827 | 1.0859 | 0.9768 | 1.0144 |
N-acetylglutamine | 0.9225 | 1.0739 | 0.9583 | 1.0565 | 0.9888 |
N-acetylglycine | 0.8880 | 1.0614 | 1.0385 | 1.0040 | 1.0082 |
N-acetylmethionine | 0.7864 | 1.1092 | 1.1643 | 0.7880 | 1.1520 |
N-acetylphenylalanine | 0.9444 | 1.0362 | 1.0670 | 0.9491 | 1.0032 |
N-acetylserine | 1.0134 | 0.9084 | 1.0491 | 1.0226 | 1.0066 |
NAD. | 0.9992 | 0.9909 | 1.0316 | 0.9963 | 0.9821 |
NADH | 0.9319 | 1.0764 | 0.8655 | 1.0957 | 1.0305 |
NADP | 0.9860 | 1.0135 | 1.0018 | 1.0144 | 0.9843 |
niacinamide | 1.0602 | 0.9856 | 0.9215 | 0.9585 | 1.0742 |
O-phosphoethanolamine | 1.1050 | 1.0121 | 0.8149 | 1.0564 | 1.0117 |
ornithine | 1.0333 | 0.9072 | 1.0101 | 1.0845 | 0.9649 |
orotate | 0.6487 | 1.1040 | 1.4981 | 0.9111 | 0.8381 |
palmitate | 1.0937 | 1.0368 | 0.8960 | 0.9948 | 0.9787 |
Pantothenate | 0.9996 | 0.9924 | 1.0394 | 0.9512 | 1.0173 |
phenylalanine | 1.0915 | 1.0117 | 0.8938 | 1.0008 | 1.0021 |
phenylalanine-13C9-15N | 1.0764 | 0.8934 | 0.9492 | 1.0213 | 1.0597 |
phosphocholine | 0.9946 | 0.9616 | 1.0621 | 1.0012 | 0.9805 |
phosphocreatine | 0.9933 | 0.9624 | 1.0626 | 1.0454 | 0.9363 |
phosphoenolpyruvate | 0.8265 | 1.2063 | 0.9663 | 0.9650 | 1.0359 |
proline | 1.0139 | 0.9630 | 0.9853 | 1.0525 | 0.9853 |
proline-13C5-15N | 1.0883 | 0.8624 | 1.0351 | 1.0488 | 0.9653 |
propionylcarnitine | 1.0362 | 1.0385 | 0.8741 | 1.0515 | 0.9996 |
pseudouridine | 0.9306 | 1.0700 | 1.0693 | 1.0059 | 0.9242 |
Pyridoxal | 1.0277 | 0.9829 | 0.8932 | 1.0027 | 1.0934 |
Pyridoxine | 1.0180 | 0.9950 | 0.9991 | 0.9821 | 1.0058 |
Ribose-1-phosphate | 1.3496 | 0.9102 | 0.3585 | 1.2491 | 1.1327 |
Ribose_Ribulose-5-phosphate-3MeLys | 0.8608 | 1.0248 | 1.1515 | 0.8070 | 1.1559 |
S-Adenosyl-L-Homocysteine | 1.0301 | 1.0261 | 1.0216 | 0.8953 | 1.0268 |
S-Adenosyl-L-methionine | 0.9720 | 0.9417 | 1.0523 | 1.0615 | 0.9725 |
Sedoheptulose-7-phosphate | 1.1178 | 0.9661 | 1.0223 | 0.9424 | 0.9513 |
serine | 1.3150 | 0.9701 | 0.4744 | 1.1547 | 1.0859 |
serine-13C3-15N | 1.0192 | 0.8408 | 0.9988 | 1.1335 | 1.0077 |
sorbitol | 0.6002 | 1.2621 | 1.2011 | 0.9445 | 0.9922 |
succinate | 0.8367 | 1.0687 | 1.1902 | 0.9349 | 0.9695 |
succinyl-CoA | 0.9633 | 1.0277 | 1.0605 | 0.9836 | 0.9648 |
taurine | 1.0469 | 0.9486 | 0.9863 | 1.0227 | 0.9955 |
threonine | 1.1341 | 0.9500 | 0.7929 | 1.0739 | 1.0492 |
threonine-13C4-15N | 1.1218 | 0.8685 | 0.8708 | 1.0538 | 1.0851 |
THYMINE-1,3-15N2 | 1.0058 | 0.9395 | 1.0470 | 1.0187 | 0.9891 |
trans-urocanate | 0.4290 | 0.6656 | 0.6251 | 1.6194 | 1.6610 |
tryptophan | 1.1069 | 1.0087 | 0.8484 | 0.9915 | 1.0445 |
tyrosine | 1.0593 | 1.0166 | 0.8792 | 1.0201 | 1.0247 |
tyrosine-13C9-15N | 1.0643 | 0.8993 | 0.9755 | 1.0528 | 1.0081 |
UDP | 1.0040 | 1.0029 | 0.8532 | 1.0840 | 1.0558 |
UDP-GlcNAc | 0.8586 | 1.0782 | 1.1755 | 0.9551 | 0.9326 |
UMP | 1.0972 | 1.0566 | 0.8418 | 0.9944 | 1.0099 |
Ureidosuccinic acid | 0.6707 | 1.0917 | 1.3283 | 0.9528 | 0.9566 |
UTP | 1.2006 | 0.9789 | 0.8933 | 0.9257 | 1.0015 |
valine | 1.1250 | 0.9962 | 0.8667 | 0.9689 | 1.0431 |
valine-13C5-15N | 1.0897 | 0.9020 | 0.9468 | 0.9982 | 1.0633 |
Factors:
F1 | Treatment:0_nM_FA |
F2 | Treatment:100_nM_FA |
F3 | Treatment:2000_nM_FA |
F4 | Treatment:20_nM_FA |
F5 | Treatment:50_nM_FA |