Data for (Study ST002919)
(Analysis AN004789)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 | F21 | F22 | F23 | F24 | F25 | F26 | F27 | F28 | F29 | F30 | F31 | F32 | F33 | F34 | F35 | F36 | F37 | F38 | F39 | F40 | F41 | F42 | F43 | F44 | F45 | F46 | F47 | F48 | F49 | F50 | F51 | F52 | F53 | F54 | F55 | F56 | F57 | F58 | F59 | F60 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acetyl-CoA | 0.1036 | 0.1366 | 0.1161 | 0.0975 | 0.0995 | NA | NA | NA | NA | NA | 0.1788 | 0.1768 | 0.1747 | 0.1566 | 0.1677 | NA | NA | NA | NA | NA | 0.5115 | 0.3925 | 0.4997 | 0.5289 | 0.6611 | NA | NA | NA | NA | NA | 1.5101 | 1.2840 | 1.4809 | 1.3918 | 1.3856 | NA | NA | NA | NA | NA | 1.9625 | 1.5728 | 1.6006 | 1.9903 | 2.0599 | NA | NA | NA | NA | NA | 3.6744 | 3.4517 | 3.5352 | 3.6466 | 4.3981 | NA | NA | NA | NA | NA |
| Alanine | 0.6842 | 0.6621 | 0.6971 | 0.6714 | 0.8144 | NA | NA | NA | NA | NA | 1.0953 | 0.9516 | 0.9895 | 0.6735 | 0.6628 | NA | NA | NA | NA | NA | 0.8944 | 1.1125 | 0.8837 | 0.9552 | 1.7589 | NA | NA | NA | NA | NA | 0.7686 | 0.8580 | 1.7667 | 1.2648 | 0.8523 | NA | NA | NA | NA | NA | 1.2026 | 1.1225 | 1.3113 | 1.2569 | 1.1111 | NA | NA | NA | NA | NA | 1.1697 | 1.0982 | 1.1011 | 1.3585 | 1.2341 | NA | NA | NA | NA | NA |
| Fructose 1,6-bisphosphate | 0.0195 | 0.0251 | 0.0183 | 0.0135 | 0.0241 | NA | NA | NA | NA | NA | 0.0391 | 0.0318 | 0.0367 | 0.0364 | 0.0230 | NA | NA | NA | NA | NA | 0.0651 | 0.0720 | 0.0536 | 0.0710 | 0.0619 | NA | NA | NA | NA | NA | 3.4983 | 4.0311 | 2.5421 | 2.8336 | 3.0903 | NA | NA | NA | NA | NA | 0.1102 | 0.0426 | 0.0413 | 0.0571 | 0.0636 | NA | NA | NA | NA | NA | 4.0754 | 2.8922 | 2.8659 | 3.1289 | 3.5496 | NA | NA | NA | NA | NA |
| Fructose 6-phosphate | 0.0525 | 0.0612 | 0.0446 | 0.0604 | 0.0594 | NA | NA | NA | NA | NA | 0.0549 | 0.0533 | 0.0535 | 0.0552 | 0.0556 | NA | NA | NA | NA | NA | 0.1969 | 0.2401 | 0.1562 | 0.1970 | 0.1803 | NA | NA | NA | NA | NA | 2.4019 | 2.3743 | 1.8568 | 1.9053 | 1.7158 | NA | NA | NA | NA | NA | 0.4947 | 0.4052 | 0.3421 | 0.2649 | 0.2438 | NA | NA | NA | NA | NA | 4.7538 | 5.2274 | 4.7889 | 4.5433 | 5.3853 | NA | NA | NA | NA | NA |
| Glucose 6-phosphate | 0.0641 | 0.0619 | 0.0308 | 0.0699 | 0.0768 | NA | NA | NA | NA | NA | 0.0713 | 0.0442 | 0.0836 | 0.0572 | 0.0491 | NA | NA | NA | NA | NA | 0.3059 | 0.2867 | 0.2489 | 0.2520 | 0.2180 | NA | NA | NA | NA | NA | 2.1442 | 2.0753 | 1.7034 | 1.6897 | 1.5655 | NA | NA | NA | NA | NA | 0.6589 | 0.4453 | 0.4489 | 0.4417 | 0.3729 | NA | NA | NA | NA | NA | 3.8377 | 4.3446 | 4.3808 | 4.3446 | 4.8152 | NA | NA | NA | NA | NA |
| Glyceraldehyde 3-phosphate | 0.0690 | 0.1000 | 0.0859 | 0.0874 | 0.0927 | NA | NA | NA | NA | NA | 0.1295 | 0.1094 | 0.1346 | 0.1356 | 0.1328 | NA | NA | NA | NA | NA | 0.3324 | 0.3079 | 0.2835 | 0.3309 | 0.2719 | NA | NA | NA | NA | NA | 2.5235 | 2.7263 | 2.6709 | 2.2022 | 2.8203 | NA | NA | NA | NA | NA | 0.3503 | 0.3553 | 0.1804 | 0.2757 | 0.3719 | NA | NA | NA | NA | NA | 3.2104 | 3.3364 | 3.8253 | 2.8778 | 4.1227 | NA | NA | NA | NA | NA |
| Lactate | 0.9627 | 1.0232 | 1.1719 | 0.7712 | 3.4376 | 0.3334 | 0.3569 | 0.3060 | 0.3410 | 0.2619 | 1.5676 | 0.8518 | 1.6004 | 1.0308 | 0.7788 | 0.3052 | 0.2601 | 0.2629 | 0.3072 | 0.2636 | 0.6275 | 0.7283 | 1.2803 | 2.0490 | 4.5616 | 0.3755 | 0.3811 | 0.4297 | 0.3826 | 0.3579 | 0.9653 | 0.9728 | 5.9578 | 3.3444 | 1.2551 | 0.6162 | 0.6386 | 0.5585 | 0.5842 | 0.5688 | 0.6401 | 0.6049 | 0.6805 | 0.3775 | 0.4879 | 0.4753 | 0.6099 | 0.3750 | 0.4279 | 0.6805 | 0.8266 | 0.5897 | 0.8216 | 0.6099 | 0.7561 | 1.0585 | 1.1341 | 1.1139 | 0.9073 | 1.1643 |
| Phosphoenolpyruvate | 0.3184 | 0.3259 | 0.3227 | 0.3110 | 0.3280 | NA | NA | NA | NA | NA | 0.3340 | 0.3330 | 0.3347 | 0.3191 | 0.3039 | NA | NA | NA | NA | NA | 1.0876 | 0.9289 | 0.8658 | 0.9201 | 0.7834 | NA | NA | NA | NA | NA | 1.4408 | 1.3247 | 1.1526 | 1.1994 | 1.1082 | NA | NA | NA | NA | NA | 1.0365 | 0.8519 | 0.7454 | 1.0010 | 1.2992 | NA | NA | NA | NA | NA | 3.9330 | 3.3083 | 3.0243 | 3.0669 | 3.6491 | NA | NA | NA | NA | NA |
| Pyruvate | 0.4697 | 0.3716 | 0.4046 | 0.5626 | 0.5636 | NA | NA | NA | NA | NA | 2.5156 | 1.6072 | 0.9899 | 0.3117 | 0.3530 | NA | NA | NA | NA | NA | 0.8320 | 1.1695 | 0.5130 | 0.6596 | 1.8467 | NA | NA | NA | NA | NA | 0.4501 | 0.6018 | 0.6947 | 0.5698 | 0.4624 | NA | NA | NA | NA | NA | 1.3543 | 1.0715 | 1.6041 | 2.7664 | 3.0761 | NA | NA | NA | NA | NA | 1.1190 | 0.9972 | 1.0962 | 2.9316 | 2.0851 | NA | NA | NA | NA | NA |
| Ribose 5-phosphate | 0.3644 | 0.3714 | 0.3843 | 0.3292 | 0.3751 | NA | NA | NA | NA | NA | 0.3068 | 0.2190 | 0.3688 | 0.3496 | 0.3339 | NA | NA | NA | NA | NA | 0.5891 | 0.5016 | 0.4453 | 0.4812 | 0.4123 | NA | NA | NA | NA | NA | 2.4522 | 2.5324 | 1.9068 | 1.8725 | 1.8127 | NA | NA | NA | NA | NA | 0.6609 | 0.3638 | 0.5350 | 0.3147 | 0.4664 | NA | NA | NA | NA | NA | 3.3296 | 2.6435 | 3.1093 | 2.4925 | 3.2667 | NA | NA | NA | NA | NA |
| Ribulose 5-phosphate | 0.3110 | 0.3704 | 0.3926 | 0.3442 | 0.3586 | NA | NA | NA | NA | NA | 0.3442 | 0.3102 | 0.3599 | 0.3638 | 0.3233 | NA | NA | NA | NA | NA | 0.4646 | 0.4712 | 0.4188 | 0.4515 | 0.3678 | NA | NA | NA | NA | NA | 2.1373 | 2.1347 | 1.8323 | 1.8585 | 1.9475 | NA | NA | NA | NA | NA | 0.4398 | 0.3167 | 0.2322 | 0.2879 | 0.2958 | NA | NA | NA | NA | NA | 3.6908 | 3.1673 | 3.3767 | 3.1411 | 3.9264 | NA | NA | NA | NA | NA |
Factors:
| F1 | Treatment:DINCH 10nM minus Insulin | Replicate:1 |
| F2 | Treatment:DINCH 10nM minus Insulin | Replicate:2 |
| F3 | Treatment:DINCH 10nM minus Insulin | Replicate:3 |
| F4 | Treatment:DINCH 10nM minus Insulin | Replicate:4 |
| F5 | Treatment:DINCH 10nM minus Insulin | Replicate:5 |
| F6 | Treatment:DINCH 10nM minus Insulin supernatant | Replicate:1 |
| F7 | Treatment:DINCH 10nM minus Insulin supernatant | Replicate:2 |
| F8 | Treatment:DINCH 10nM minus Insulin supernatant | Replicate:3 |
| F9 | Treatment:DINCH 10nM minus Insulin supernatant | Replicate:4 |
| F10 | Treatment:DINCH 10nM minus Insulin supernatant | Replicate:5 |
| F11 | Treatment:DINCH 10nM plus Insulin | Replicate:1 |
| F12 | Treatment:DINCH 10nM plus Insulin | Replicate:2 |
| F13 | Treatment:DINCH 10nM plus Insulin | Replicate:3 |
| F14 | Treatment:DINCH 10nM plus Insulin | Replicate:4 |
| F15 | Treatment:DINCH 10nM plus Insulin | Replicate:5 |
| F16 | Treatment:DINCH 10nM plus Insulin supernatant | Replicate:1 |
| F17 | Treatment:DINCH 10nM plus Insulin supernatant | Replicate:2 |
| F18 | Treatment:DINCH 10nM plus Insulin supernatant | Replicate:3 |
| F19 | Treatment:DINCH 10nM plus Insulin supernatant | Replicate:4 |
| F20 | Treatment:DINCH 10nM plus Insulin supernatant | Replicate:5 |
| F21 | Treatment:DINCH 10µM minus Insulin | Replicate:1 |
| F22 | Treatment:DINCH 10µM minus Insulin | Replicate:2 |
| F23 | Treatment:DINCH 10µM minus Insulin | Replicate:3 |
| F24 | Treatment:DINCH 10µM minus Insulin | Replicate:4 |
| F25 | Treatment:DINCH 10µM minus Insulin | Replicate:5 |
| F26 | Treatment:DINCH 10µM minus Insulin supernatant | Replicate:1 |
| F27 | Treatment:DINCH 10µM minus Insulin supernatant | Replicate:2 |
| F28 | Treatment:DINCH 10µM minus Insulin supernatant | Replicate:3 |
| F29 | Treatment:DINCH 10µM minus Insulin supernatant | Replicate:4 |
| F30 | Treatment:DINCH 10µM minus Insulin supernatant | Replicate:5 |
| F31 | Treatment:DINCH 10µM plus Insulin | Replicate:1 |
| F32 | Treatment:DINCH 10µM plus Insulin | Replicate:2 |
| F33 | Treatment:DINCH 10µM plus Insulin | Replicate:3 |
| F34 | Treatment:DINCH 10µM plus Insulin | Replicate:4 |
| F35 | Treatment:DINCH 10µM plus Insulin | Replicate:5 |
| F36 | Treatment:DINCH 10µM plus Insulin supernatant | Replicate:1 |
| F37 | Treatment:DINCH 10µM plus Insulin supernatant | Replicate:2 |
| F38 | Treatment:DINCH 10µM plus Insulin supernatant | Replicate:3 |
| F39 | Treatment:DINCH 10µM plus Insulin supernatant | Replicate:4 |
| F40 | Treatment:DINCH 10µM plus Insulin supernatant | Replicate:5 |
| F41 | Treatment:Rosiglitazone minus insulin | Replicate:1 |
| F42 | Treatment:Rosiglitazone minus insulin | Replicate:2 |
| F43 | Treatment:Rosiglitazone minus insulin | Replicate:3 |
| F44 | Treatment:Rosiglitazone minus insulin | Replicate:4 |
| F45 | Treatment:Rosiglitazone minus insulin | Replicate:5 |
| F46 | Treatment:Rosiglitazone minus insulin supernatant | Replicate:1 |
| F47 | Treatment:Rosiglitazone minus insulin supernatant | Replicate:2 |
| F48 | Treatment:Rosiglitazone minus insulin supernatant | Replicate:3 |
| F49 | Treatment:Rosiglitazone minus insulin supernatant | Replicate:4 |
| F50 | Treatment:Rosiglitazone minus insulin supernatant | Replicate:5 |
| F51 | Treatment:Rosiglitazone plus insulin | Replicate:1 |
| F52 | Treatment:Rosiglitazone plus insulin | Replicate:2 |
| F53 | Treatment:Rosiglitazone plus insulin | Replicate:3 |
| F54 | Treatment:Rosiglitazone plus insulin | Replicate:4 |
| F55 | Treatment:Rosiglitazone plus insulin | Replicate:5 |
| F56 | Treatment:Rosiglitazone plus insulin supernatant | Replicate:1 |
| F57 | Treatment:Rosiglitazone plus insulin supernatant | Replicate:2 |
| F58 | Treatment:Rosiglitazone plus insulin supernatant | Replicate:3 |
| F59 | Treatment:Rosiglitazone plus insulin supernatant | Replicate:4 |
| F60 | Treatment:Rosiglitazone plus insulin supernatant | Replicate:5 |
