Data for (Study ST002976)
(Analysis AN004886)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 11a-Hydroxyprogesterone | 1.0563 | 1.1885 | 0.9565 | 0.7359 |
| 1,3,7-Trimethyluric acid | 1.0613 | 1.2390 | 0.3725 | 0.9125 |
| 17-Hydroxyprogesterone | 1.0236 | 0.8941 | 1.0416 | 1.0516 |
| 1-Methyladenosine | 0.9738 | 1.2635 | 0.6780 | 0.9412 |
| 2,2-Dimethylsuccinic acid | 1.0193 | 1.1351 | 0.9285 | 0.9100 |
| 2,3-Butanediol | 1.0798 | 1.0237 | 0.9956 | 0.9134 |
| 2,3-Diaminopropionic acid | 1.0904 | 1.0505 | 1.0235 | 0.8506 |
| 2^-Deoxyguanosine 5^-monophosphate | 0.4643 | 0.3564 | 0.7446 | 2.1295 |
| 2-Ethyl-2-hydroxybutyric acid | 1.0557 | 0.8868 | 1.0242 | 1.0525 |
| 2-Hydroxyadenine | 1.2195 | 1.4440 | 0.2344 | 1.0111 |
| 2-Methyl-3-ketovaleric acid | 0.9341 | 1.0183 | 1.1533 | 0.9335 |
| 2-Phenylbutyric acid | 1.0371 | 1.0253 | 0.9969 | 0.9463 |
| 2-Pyrrolidinone | 0.9572 | 0.5732 | 1.6206 | 0.9453 |
| 3a,6b,7b-Trihydroxy-5b-cholanoic acid | 0.8367 | 0.9256 | 1.3558 | 0.9671 |
| 3b-Hydroxy-5-cholenoic acid | 0.9807 | 0.9496 | 1.0559 | 1.0200 |
| 3-Hexenedioic acid | 1.0746 | 1.0107 | 0.6968 | 1.1798 |
| 3-Methylhistamine | 0.8973 | 0.9747 | 1.4604 | 0.7079 |
| 3-Methylindole | 0.9358 | 0.5244 | 1.9500 | 0.6978 |
| 3-Nitrotyrosine | 1.1549 | 1.4505 | 0.2765 | 0.4583 |
| 3-Phenylbutyric acid | 0.9909 | 1.0087 | 0.9957 | 1.0025 |
| 4-Guanidinobutanoic acid | 1.0971 | 0.8111 | 1.3275 | 0.8893 |
| 5-Aminolevulinic acid | 1.0382 | 1.1175 | 0.6549 | 1.1382 |
| 5-Hydroxytryptophol | 1.0622 | 0.8414 | 1.3562 | 0.7148 |
| 5-Methoxytryptophan | 1.0852 | 1.1790 | 1.1037 | 0.7453 |
| 5-Methoxytryptophol | 1.0456 | 1.1034 | 1.0575 | 0.8039 |
| 5^-Methylthioadenosine | 0.8354 | 0.8007 | 1.3660 | 1.0314 |
| 5-Phenylvaleric acid | 1.0543 | 1.0070 | 0.7530 | 1.1602 |
| 6-(Methylamino) purine | 1.0943 | 0.9722 | 1.1729 | 0.7174 |
| 7-Methylguanine | 1.7688 | 0.8591 | 0.3051 | 0.8842 |
| 7-Methylxanthine | 0.9589 | 1.1020 | 0.9733 | 0.9545 |
| 8,11,14-Eicosatrienoic acid | 1.0802 | 0.9585 | 1.0272 | 0.9520 |
| Acetoin | 0.9901 | 1.1323 | 0.9844 | 0.8890 |
| Acetone | 1.0557 | 0.9343 | 1.0134 | 1.0081 |
| Acrylamide | 0.8171 | 0.9351 | 1.3885 | 0.9205 |
| Adenine | 0.3776 | 0.8341 | 2.5754 | 0.3717 |
| Adenosine | 0.3603 | 0.8639 | 2.5980 | 0.3375 |
| Adenosine monophosphate | 0.4030 | 0.5059 | 2.0200 | 1.0919 |
| Adenylsuccinic acid | 0.5242 | 0.4959 | 2.3157 | 0.6083 |
| ADP | 0.8646 | 1.0876 | 0.9604 | 1.0651 |
| All-trans-retinoic acid | 0.9195 | 1.1209 | 0.9859 | 0.9613 |
| Alpha-hydroxyhippuric acid | 0.6890 | 0.8658 | 1.4525 | 0.9467 |
| Aminoadipic acid | 0.7424 | 0.5758 | 2.1387 | 0.6684 |
| Androstenedione | 0.9730 | 0.9533 | 1.0028 | 1.0669 |
| Androsterone | 0.9899 | 1.0057 | 0.9971 | 1.0056 |
| Aniline | 0.9592 | 0.8140 | 1.1848 | 1.0606 |
| Aspartame | 1.6636 | 0.9224 | 0.5680 | 0.8741 |
| Asymmetric dimethylarginine | 1.1499 | 1.1037 | 0.7415 | 0.9867 |
| Atenolol | 0.6975 | 0.3425 | 2.3936 | 0.6656 |
| Benzaldehyde | 1.1673 | 0.7985 | 0.8897 | 1.1540 |
| Benzoic acid | 1.1859 | 1.0115 | 0.7969 | 1.0283 |
| Beta-Alanine | 1.3565 | 0.9149 | 0.7031 | 1.0354 |
| Butanone | 0.7340 | 0.8870 | 0.9464 | 1.3801 |
| Cis-Aconitic acid | 0.8493 | 1.3263 | 0.9443 | 0.6584 |
| Cortexolone | 2.6051 | 0.4823 | 0.6190 | 0.3915 |
| Cortisol | 1.3613 | 0.9119 | 0.8103 | 0.9128 |
| Creatine | 1.3628 | 1.2275 | 0.5610 | 1.0187 |
| Creatinine | 0.9292 | 0.6516 | 1.2063 | 1.0342 |
| Cyclic AMP | 1.0812 | 0.9896 | 0.2232 | 1.4009 |
| Cytidine | 1.0475 | 1.0463 | 0.7903 | 1.1502 |
| Cytidine monophosphate | 0.8126 | 1.3316 | 0.1780 | 1.1947 |
| Cytosine | 0.9516 | 1.5147 | 0.0595 | 1.2520 |
| Daidzein | 0.9896 | 1.2660 | 0.6465 | 0.9740 |
| D-Arginine | 1.6241 | 0.7488 | 0.8823 | 0.7762 |
| DCMP | 1.0392 | 1.0429 | 1.1252 | 0.8230 |
| Deoxyadenosine | 0.4154 | 0.5216 | 2.0873 | 0.3233 |
| Deoxyadenosine monophosphate | 0.9719 | 1.0189 | 1.0030 | 1.0057 |
| Deoxycytidine | 1.2446 | 1.0258 | 0.7935 | 0.9425 |
| Deoxyinosine | 0.9167 | 1.1607 | 0.4225 | 0.9881 |
| DGTP | 1.0441 | 1.0928 | 0.9614 | 0.9104 |
| Diacetyl | 1.0033 | 1.0116 | 0.9854 | 0.9978 |
| Digoxin | 0.9939 | 1.2853 | 0.8784 | 0.7732 |
| DL-2-aminooctanoic acid | 0.8811 | 0.8698 | 0.8148 | 1.3681 |
| D-Serine | 1.4272 | 0.6812 | 0.3521 | 1.3824 |
| Elaidic acid | 0.9855 | 0.9320 | 1.0870 | 1.0076 |
| Epicatechin | 1.0916 | 1.3070 | 0.7988 | 0.6161 |
| Estriol | 0.7620 | 1.1827 | 0.9425 | 1.0982 |
| Ethanolamine | 0.9959 | 0.8881 | 1.0449 | 1.0846 |
| Flavin mononucleotide | 0.7035 | 0.7174 | 1.3599 | 0.9121 |
| Galactitol | 1.1232 | 1.2101 | 0.8983 | 0.6473 |
| Glucaric acid | 1.0320 | 1.3036 | 0.7515 | 0.8657 |
| Glucosamine | 0.8568 | 1.3329 | 0.5752 | 1.1146 |
| Glutathione | 1.2962 | 1.0279 | 0.3832 | 1.2392 |
| Glycerophosphocholine | 1.1456 | 0.7835 | 1.2199 | 0.9120 |
| Glycocholic acid | 1.1657 | 1.0334 | 0.7877 | 0.9468 |
| Guanosine | 1.2921 | 1.4312 | 0.2511 | 0.9495 |
| Guanosine 5^-diphosphate | 1.0526 | 0.7714 | 1.1745 | 0.9996 |
| Guanosine monophosphate | 0.7324 | 0.9570 | 1.1416 | 1.1615 |
| Hippuric acid | 0.9354 | 1.1580 | NA | 0.8034 |
| Histamine | 1.1949 | 0.9383 | 1.2547 | 0.6353 |
| Homocitrulline | 1.1033 | 0.9683 | 1.0881 | 0.8642 |
| Hydrocinnamic acid | 1.1446 | 1.0359 | 0.6201 | 1.1031 |
| Hydroxyoctanoic acid | 0.9736 | 1.0465 | 0.9838 | 0.9891 |
| Hypoxanthine | 1.0657 | 1.0666 | 0.8215 | 1.0275 |
| Ibuprofen | 0.9772 | 0.8955 | 1.0619 | 1.0719 |
| Indole | 1.3506 | 0.9132 | 0.7534 | 0.9651 |
| Indole-3-carbinol | 1.1415 | 0.9948 | 1.0978 | 0.8006 |
| Indoleacrylic acid | 1.2839 | 0.7541 | 0.5665 | 1.2655 |
| Inosine | 1.0785 | 1.0726 | 0.7842 | 1.0418 |
| Isocaproic acid | 1.0207 | 1.0387 | 1.0107 | 0.9352 |
| Isopropyl alcohol | 1.0107 | 1.0112 | 0.9008 | 1.0598 |
| Isovalerylcarnitine | 1.0396 | 0.9574 | 0.9978 | 1.0115 |
| Isovalerylglycine | 1.1678 | 1.2403 | 0.6428 | 0.8580 |
| L-Acetylcarnitine | 1.0355 | 1.0300 | 0.7080 | 1.1838 |
| L-Alanine | 1.3464 | 0.8940 | 0.5231 | 1.0730 |
| L-Aspartic acid | 1.0393 | 1.0026 | 1.0312 | 0.9005 |
| L-Aspartyl-L-phenylalanine | 1.3560 | 0.7330 | 1.0118 | 0.9604 |
| L-Carnitine | 0.9498 | 1.3090 | 0.7555 | 0.9365 |
| Leucinic acid | 1.0938 | 0.8778 | 1.2078 | 0.9218 |
| L-Fucose | 0.9889 | 1.1476 | 0.9691 | 0.8649 |
| L-Glutamic acid | 1.2644 | 1.2101 | 0.8272 | 0.7136 |
| L-Isoleucine | 1.1625 | 1.0035 | 0.6244 | 1.1741 |
| L-Kynurenine | 1.1556 | 1.0840 | 0.8541 | 0.8643 |
| L-Leucine | 1.3961 | 1.1083 | 0.7403 | 0.7984 |
| L-Malic acid | 1.1973 | 1.4277 | 0.3674 | 0.9350 |
| L-Methionine | 1.2292 | 1.0466 | 0.5294 | 1.1153 |
| L(-)-Nicotine pestanal | 0.7553 | 0.6478 | 1.8308 | 0.8638 |
| L-Norleucine | 0.9363 | 1.1385 | 0.8850 | 1.0103 |
| L-Phenylalanine | 1.3998 | 0.9116 | 0.7950 | 0.9261 |
| L-Proline | 1.0064 | 0.9238 | 1.1412 | 0.9532 |
| L-Valine | 1.2312 | 0.8702 | 0.7477 | 1.1474 |
| Maltitol | 1.0902 | 1.4035 | 0.8082 | 0.6812 |
| m-Coumaric acid | 1.2262 | 0.9751 | 0.9321 | 0.8623 |
| Medroxyprogesterone | 0.9654 | 0.9528 | 1.0617 | 1.0246 |
| Melatonin | 0.7909 | 1.0836 | 1.2896 | 0.8318 |
| Methylglutaric acid | 1.0173 | 1.1080 | 0.7486 | 1.0871 |
| Methylmalonic acid | 0.8765 | 0.8176 | 1.2326 | 1.1210 |
| Methylsuccinic acid | 1.0413 | 1.0278 | 1.0046 | 0.9317 |
| Metoprolol | 0.9469 | 1.2458 | 0.9481 | 0.8417 |
| N1-Acetylspermine | 1.0142 | 0.9790 | NA | 1.0183 |
| N6-Acetyl-L-lysine | 1.1251 | 0.9934 | 1.0195 | 0.8862 |
| N-Acetylglutamic acid | 1.2164 | 1.2785 | 0.7157 | 0.9096 |
| N-Acetyllactosamine | 0.2336 | 0.3918 | 1.5219 | 0.2941 |
| N-Acetyl-L-alanine | 1.0611 | 1.0838 | 0.8769 | 0.9576 |
| N-Acetyl-L-phenylalanine | 0.8119 | 0.9400 | 1.4375 | 0.8038 |
| N-Acetylneuraminic acid | 0.8740 | 0.8157 | 1.2015 | 1.1152 |
| N-Acetylserotonin | 1.0380 | 0.9949 | 0.9456 | 1.0188 |
| NADPH | 1.3226 | 0.8373 | 0.9457 | 1.0696 |
| Naringenin | 0.9828 | 0.9961 | 1.1550 | 0.8881 |
| Niacinamide | 1.7218 | 1.0062 | 0.3749 | 0.9710 |
| N-Methyl-a-aminoisobutyric acid | 1.3876 | 0.7949 | 0.9381 | 0.9660 |
| N-Methyl-D-aspartic acid | 0.4946 | 0.8600 | 2.3839 | 0.4079 |
| N-Methylnicotinamide | 0.8844 | 0.9218 | 1.1944 | 1.0333 |
| N,N-Dimethylformamide | 0.8998 | 1.0130 | 1.2001 | 0.8746 |
| Normetanephrine | 1.0384 | 0.9436 | 0.7070 | 1.1145 |
| Nutriacholic acid | 0.9830 | 1.0292 | 0.9406 | 1.0345 |
| Oleic acid | 0.9725 | 0.9738 | 1.0188 | 1.0209 |
| O-Phosphoethanolamine | 1.1048 | 1.0823 | 0.9073 | 0.9164 |
| o-Tyrosine | 1.3320 | 1.1673 | 0.8960 | 0.6427 |
| Pantothenic acid | 0.9612 | 0.9625 | 1.2026 | 0.9178 |
| PC(16:0/16:0) | 0.6121 | 0.8354 | 1.2429 | 1.3114 |
| PC(18:1(9Z)/18:1(9Z)) | 0.7907 | 1.1898 | 0.9986 | 0.9858 |
| Perillic acid | 0.9773 | 1.0342 | 1.0028 | 0.9824 |
| Phenol | 1.0244 | 0.7725 | 1.0098 | 1.1998 |
| Phenylacetaldehyde | 0.9008 | 0.7907 | 0.9489 | 1.3346 |
| Phenylacetic acid | 1.0952 | 0.9773 | 1.0319 | 0.9326 |
| Phenylacetylglycine | 0.8501 | 0.8360 | 1.6779 | 0.7115 |
| Phenylpropanolamine | 0.9618 | 1.1196 | 1.0183 | 0.8970 |
| Phosphoric acid | 1.0538 | 1.0158 | 1.0453 | 0.9016 |
| Pipecolic acid | 0.9567 | 0.9816 | 1.1236 | 0.9515 |
| p-Octopamine | 1.0243 | 0.9376 | 1.1209 | 0.9383 |
| Pregnenolone | 1.0067 | 0.9966 | 0.9949 | 1.0020 |
| Pregnenolone sulfate | 1.0227 | 1.0777 | 1.0624 | 0.8654 |
| Pterin | 1.0960 | 1.3185 | 0.4709 | 1.0424 |
| Putrescine | 0.8668 | 1.3513 | 0.7699 | 0.8937 |
| Pyridine | 1.2090 | 0.9666 | 0.4639 | 1.3060 |
| Pyridoxine | 0.9323 | 1.2676 | 0.7853 | 0.9078 |
| Pyrocatechol | 0.9884 | 1.1376 | 0.5869 | 1.0275 |
| Pyroglutamic acid | 0.8336 | 0.8887 | 1.1619 | 1.0604 |
| Pyrrolidonecarboxylic acid | 1.0217 | 0.7900 | 0.8985 | 1.2765 |
| Pyruvaldehyde | 0.9978 | 1.0182 | 0.9812 | 0.9993 |
| Quinic acid | 1.0783 | 1.1413 | 0.7878 | 0.9147 |
| Riboflavin | 0.9685 | 1.0380 | 0.6434 | 1.2854 |
| Saccharopine | 1.0372 | 0.9500 | 1.1012 | 0.9347 |
| Salbutamol | 0.7447 | 1.0413 | 1.6374 | 0.6961 |
| Sebacic acid | 1.0451 | 0.9928 | 0.9755 | 0.9900 |
| Sorbitol | 1.2837 | 0.6613 | 0.8062 | 1.0868 |
| Spermine | 1.1020 | 1.5832 | 0.0502 | 0.8067 |
| Sphinganine | 0.8223 | 1.5500 | 0.7436 | 0.7623 |
| Sphingosine | 1.1350 | 0.8809 | 1.0835 | 0.9483 |
| Stearic acid | 1.0953 | 1.1024 | 0.9892 | 0.8681 |
| Succinic acid semialdehyde | 1.0475 | 0.7569 | 1.1151 | 1.0154 |
| Succinylacetone | 0.9547 | 0.6827 | 1.4185 | 0.9856 |
| Sulfolithocholic acid | 1.0328 | 1.2752 | 0.9585 | 0.8549 |
| Taurodeoxycholic acid | 1.0915 | 1.0887 | 0.9488 | 0.9011 |
| Testosterone | 0.9667 | 1.0638 | 1.2062 | 0.7921 |
| Thiamine | 0.7599 | 0.5913 | 1.4230 | 1.2577 |
| Thymine | 0.9620 | 1.1532 | 0.6135 | 1.0782 |
| Thymol | 1.0872 | 0.8614 | 1.3232 | 0.7942 |
| Tiglylglycine | 0.8862 | 0.9132 | 1.1764 | 1.0415 |
| Tolnaftate | 0.8616 | 1.0296 | 1.1110 | 0.9562 |
| Traumatic acid | 0.7147 | 1.4050 | 0.6794 | 1.1355 |
| Triamterene | 1.0305 | 0.7038 | 1.2512 | 0.7585 |
| Triethylamine | 0.5945 | 0.8547 | 1.4838 | 1.0505 |
| Trimethylamine | 1.0457 | 0.9605 | 0.7513 | 1.2087 |
| Tryptophanol | 0.8848 | 1.0337 | 1.3143 | 0.8266 |
| Tyramine | 0.9598 | 0.9292 | 1.0726 | 1.0439 |
| Uracil | 1.1698 | 1.7186 | 0.6334 | 0.4748 |
| Urea | 1.2199 | 0.9623 | 0.7668 | 1.0487 |
| Ureidopropionic acid | 1.1567 | 1.0137 | NA | 0.8310 |
| Uric acid | 0.8309 | 0.9226 | 0.4702 | 1.4612 |
| Uridine | 1.2032 | 0.8925 | 1.1489 | 0.8140 |
| Uridine 5^-monophosphate | 1.4644 | 1.4616 | 0.7904 | 0.2961 |
| Urocanic acid | 2.4153 | 0.1437 | 1.2821 | 0.4419 |
| Xanthine | 0.8850 | 1.0389 | 0.8244 | 1.1969 |
| Xanthurenic acid | 0.9900 | 0.9405 | 0.9861 | 1.1451 |
Factors:
| F1 | Treatment:5-fluorouracil |
| F2 | Treatment:Doxorubicin |
| F3 | Treatment:Doxorubicin + 5-fluorouracil |
| F4 | Treatment:Positive Control |
