Data for (Study ST002999)

(Analysis AN004926)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

MetaboliteF1F2F3F4F5F6F7F8F9F10F11F12F13F14F15
Adenosine triphosphate (ATP) 0.9543 1.0503 1.2222 1.8244 0.6454 0.6180 0.6136 NA 0.7075 1.3609 1.4381 1.1756 0.8443 0.8256 0.7196
Citric acid 2.1997 0.1557 0.1062 0.8957 0.1045 0.0962 0.9361 NA 3.0093 0.0886 0.1503 3.2843 0.0816 0.1454 2.7465
D-Glucose 6-phosphate NA 0.9600 0.5782 NA 0.9943 0.5401 NA NA NA 1.7391 0.9052 NA 1.4963 0.7868 NA
D-Glyceraldehyde 3-phosphate 1.3741 0.5782 0.7640 0.7977 0.7965 0.4978 0.1115 NA 1.4603 1.2975 1.5633 1.6777 1.4913 1.1253 0.4647
D-Glycerate 3-phosphate 1.2398 0.2375 1.0005 0.8843 0.4783 0.5822 0.5127 NA 1.3437 0.7445 1.9988 1.9268 0.8892 1.1484 1.0133
Fumaric acid 1.3121 0.1400 0.7155 2.3565 0.2013 0.3214 1.8053 NA 1.0337 0.6977 0.9188 1.7345 0.4039 0.6323 1.7269
Guanosine triphosphate (GTP) 1.7504 0.9740 0.9177 1.3767 0.4810 0.3539 0.5977 NA 1.3353 1.2035 1.2342 1.5524 0.6981 0.6327 0.8925
L-Glutamate 0.4928 1.5313 0.9903 1.6657 0.8088 0.4708 0.7742 NA 0.4094 1.6330 1.1207 1.8500 0.7248 0.4696 1.0586
L-Glutamine 1.8245 NA NA 0.3771 NA NA 0.3630 NA 2.1595 NA NA 0.5850 NA NA 0.6910
L-Lactic acid 1.2416 0.5703 1.7508 1.4390 0.1761 0.3175 0.2792 NA 1.3111 0.6284 2.2255 2.4337 0.2531 0.7569 0.6168
L-Malic acid 0.7583 0.3047 0.8709 2.5370 0.2632 0.4735 0.0011 NA 1.3848 0.8536 1.1032 2.4814 0.4763 0.7628 1.7291
L-Serine 1.5649 0.3908 0.3289 1.7691 0.4530 0.5934 1.5262 NA 1.4834 0.5099 0.1900 2.1195 0.3189 0.3320 2.4200
Oxoglutaric acid 0.1869 1.4321 0.7704 1.9567 1.1283 0.7308 2.3779 NA 0.1791 1.3646 0.8299 0.4578 0.6504 0.6365 1.2986
Pyruvate 0.6918 1.0730 0.7193 1.5492 0.1680 0.1174 0.7435 NA 0.6360 0.8725 0.4878 3.7979 0.3082 0.2400 2.5953
Succinic acid 1.2439 0.8781 0.8716 1.6984 0.2649 0.3514 0.7713 NA 1.4573 0.8921 1.0383 2.1736 0.4810 0.5151 1.3630
Uridine triphosphate (UTP) 0.4662 1.6873 1.5759 1.5044 0.7176 0.6598 0.2334 NA 0.3548 2.1165 1.7276 0.4036 1.0513 0.9504 0.2956
Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1Genotype:Empty vector | Treatment:CB-839 | Timepoint:8 hours | Tracer:U-C13 Glutamine
F2Genotype:Empty vector | Treatment:DMSO | Timepoint:1 hour | Tracer:U-C13 Glucose
F3Genotype:Empty vector | Treatment:DMSO | Timepoint:24 hours | Tracer:U-C13 Glucose
F4Genotype:Empty vector | Treatment:DMSO | Timepoint:8 hours | Tracer:U-C13 Glutamine
F5Genotype:Empty vector | Treatment:Romidepsin | Timepoint:1 hour | Tracer:U-C13 Glucose
F6Genotype:Empty vector | Treatment:Romidepsin | Timepoint:24 hours | Tracer:U-C13 Glucose
F7Genotype:Empty vector | Treatment:Romidepsin | Timepoint:8 hours | Tracer:U-C13 Glutamine
F8Genotype:NA | Treatment:NA | Timepoint:NA | Tracer:NA
F9Genotype:NRF2 overexpression | Treatment:CB-839 | Timepoint:8 hours | Tracer:U-C13 Glutamine
F10Genotype:NRF2 overexpression | Treatment:DMSO | Timepoint:1 hour | Tracer:U-C13 Glucose
F11Genotype:NRF2 overexpression | Treatment:DMSO | Timepoint:24 hours | Tracer:U-C13 Glucose
F12Genotype:NRF2 overexpression | Treatment:DMSO | Timepoint:8 hours | Tracer:U-C13 Glutamine
F13Genotype:NRF2 overexpression | Treatment:Romidepsin | Timepoint:1 hour | Tracer:U-C13 Glucose
F14Genotype:NRF2 overexpression | Treatment:Romidepsin | Timepoint:24 hours | Tracer:U-C13 Glucose
F15Genotype:NRF2 overexpression | Treatment:Romidepsin | Timepoint:8 hours | Tracer:U-C13 Glutamine
  logo