Data for (Study ST003072)
(Analysis AN005030)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| acetylcarnitine | 0.0914 | 0.1270 | 0.1248 | 0.1140 | 2.1520 | 2.4017 | 0.2329 | NA | NA | 0.5632 | 0.2687 | 0.3124 | 2.0515 | 1.9615 |
| adenine | 1.1254 | 1.3393 | 0.9701 | 1.4374 | 0.9449 | 0.8294 | 1.5566 | 1.0775 | NA | 1.1275 | 1.1761 | NA | 0.1899 | 0.1610 |
| adenosine | 0.8982 | 2.0728 | 1.0040 | 1.2234 | 1.2512 | 0.6355 | 0.8728 | 1.2319 | 0.5911 | 0.3711 | 0.5325 | 0.6088 | 0.3426 | 0.4397 |
| alanine | 1.0511 | 0.9680 | 0.9618 | 0.9485 | 1.2187 | 1.3909 | NA | 0.3393 | NA | 0.2244 | NA | NA | 0.7130 | 0.6222 |
| allantoin | 1.5613 | 0.9937 | 1.6759 | 1.1433 | 0.8504 | 1.0715 | 0.0618 | 0.4722 | 0.0799 | 0.2775 | 0.2675 | 0.0585 | 1.0274 | 0.8109 |
| Alpha.Ketoglutarate | 0.6784 | 0.4231 | 0.4078 | 0.3454 | 2.0135 | 2.1321 | 0.9721 | 1.0599 | NA | 0.6209 | 1.5967 | 1.0170 | 0.3813 | 0.4120 |
| alpha.keto.isovalerate | 1.2052 | 1.0991 | 1.0590 | 1.0776 | 1.0251 | 1.1629 | NA | NA | NA | NA | NA | NA | 0.3346 | 0.3134 |
| AMP | 0.4838 | 0.8112 | 0.5649 | 0.9574 | 1.9256 | 0.9251 | NA | NA | NA | NA | NA | NA | NA | NA |
| anserine | 1.0259 | 1.4140 | 1.5656 | 1.5265 | 0.0843 | 0.1388 | 1.0798 | NA | NA | 0.3010 | 0.8295 | 0.6753 | 1.7343 | 2.2014 |
| argininosuccinate | 1.7947 | 2.0145 | 1.3407 | 1.7311 | 0.2628 | 0.1567 | NA | NA | NA | NA | NA | NA | 0.0809 | 0.1082 |
| asparagine | 0.3358 | 0.4340 | 0.2887 | 0.3567 | 2.0758 | 2.2891 | NA | 1.5095 | NA | 0.3321 | 0.3617 | 0.9697 | 0.8775 | 0.7933 |
| betaine | 0.1194 | 0.1733 | 0.1179 | 0.1437 | 2.1582 | 2.4824 | 1.1164 | 2.2257 | 0.8781 | 0.6788 | 1.1034 | 0.9844 | 1.0828 | 0.7134 |
| biotin | 0.8275 | 0.5380 | 0.7567 | 0.5120 | 2.4070 | 0.8194 | NA | NA | NA | NA | NA | NA | 0.8885 | 0.7771 |
| Butyrylcarnitine | 0.0670 | 0.0941 | 0.0780 | 0.0725 | 2.3299 | 2.5624 | NA | NA | NA | NA | NA | NA | 0.6131 | 0.6109 |
| C5.Carnitines | 0.1836 | 0.2118 | 0.2220 | 0.2189 | 1.6837 | 2.0682 | 1.6797 | 3.3702 | 2.0773 | NA | NA | 3.0772 | 0.4385 | 0.4068 |
| carnitine | 0.2417 | 0.2786 | 0.2245 | 0.2447 | 2.5417 | 2.8638 | 0.0794 | 0.1423 | 0.1201 | 0.1967 | 0.1121 | 0.2381 | 1.2303 | 0.8328 |
| carnosine | 1.5735 | 2.0072 | 1.4774 | 1.9746 | 0.0440 | 0.0434 | NA | NA | NA | NA | NA | 2.1208 | 0.0933 | 0.0624 |
| cis.aconitate | 1.1538 | 1.2723 | 0.9827 | 1.2581 | 0.8314 | 1.0361 | 1.5670 | 0.7986 | 0.8343 | 0.4165 | 1.6718 | 1.2800 | 0.3273 | 0.3862 |
| citrate | 0.6235 | 0.7725 | 0.7011 | 0.8656 | 0.7934 | 0.8282 | 3.3935 | 1.3755 | 1.2499 | 0.7326 | 4.1513 | 3.6740 | 0.3236 | 0.4088 |
| citrulline | 0.6150 | 0.5267 | 0.4754 | 0.5327 | 0.8093 | 0.7371 | 2.2335 | 1.5683 | 2.9679 | 0.9374 | 0.9849 | 1.9914 | 2.3178 | 2.1749 |
| CMP | NA | 0.1054 | NA | NA | 1.7560 | 0.9891 | NA | NA | NA | NA | NA | NA | 0.0507 | 0.0130 |
| creatine | 1.3509 | 1.4331 | 1.5922 | 1.5726 | 0.8494 | 0.9821 | 0.1236 | 0.1794 | 0.2465 | 0.3079 | 0.1514 | 0.4002 | 0.4327 | 0.3864 |
| creatinine | 1.2228 | 1.7190 | 1.8101 | 1.8463 | 0.4025 | 0.5064 | 0.3197 | 0.7897 | 0.4391 | 0.5054 | 0.4139 | 0.8205 | 0.4417 | 0.4455 |
| cystine | 0.3471 | 0.4758 | 0.1339 | 0.5155 | 1.9174 | 2.6668 | NA | NA | NA | NA | NA | NA | 0.5517 | 0.0432 |
| cytidine | 0.8881 | 0.5995 | 0.8206 | 0.6236 | 2.2112 | 0.7856 | NA | NA | NA | NA | NA | NA | 0.8649 | 0.7795 |
| cytosine | 0.8594 | 0.5015 | 0.7351 | 0.5679 | 2.3177 | 0.8519 | NA | NA | NA | NA | NA | NA | 0.9325 | 0.8157 |
| dCytidine | 1.5548 | 0.9250 | 1.8349 | 1.0654 | 1.0095 | 1.1750 | 0.1025 | 0.0955 | 0.1176 | 0.3436 | 0.0785 | 0.0768 | 0.8003 | 0.5711 |
| dimethylglicine | NA | NA | NA | 0.2916 | 0.9404 | 1.1206 | NA | NA | NA | NA | NA | NA | 1.2837 | 0.9181 |
| formyl_methionine | 1.0349 | 1.2636 | 0.9791 | 1.2280 | 0.4563 | 0.5751 | NA | NA | NA | NA | NA | NA | 1.5723 | 1.8382 |
| fumarate | 0.9181 | 0.8544 | 0.7055 | 0.6935 | 1.5691 | 1.5092 | NA | NA | NA | NA | NA | NA | 0.4032 | 0.5580 |
| gamma.glutamyl.alanine | 0.1963 | 0.1073 | 0.1226 | 0.1617 | 2.0011 | 2.4677 | NA | NA | NA | NA | NA | NA | 1.1294 | 0.6649 |
| Glucose.6.phosphate | 1.3638 | 1.4149 | 1.0701 | 1.2151 | 0.4391 | 0.3690 | NA | NA | NA | NA | NA | NA | 1.1836 | 1.6682 |
| glutamate | 0.2865 | 0.6198 | 0.2782 | 0.4295 | 0.7289 | 0.3839 | 4.2927 | 2.0739 | 1.5958 | 1.9357 | 3.1719 | 3.3045 | 1.7305 | 2.0719 |
| glutamine | 1.9613 | 1.9345 | 1.8349 | 2.0858 | 0.3368 | 0.3629 | 0.0396 | 0.0376 | 0.0368 | 0.0599 | 0.0366 | 0.0315 | 0.2880 | 0.2089 |
| Glycerol.3.Phosphate | 1.5544 | 1.4565 | 1.2288 | 1.5278 | 0.4502 | 0.5398 | NA | NA | NA | NA | NA | NA | 0.5121 | 0.4779 |
| Glycerophosphocholine | 0.3331 | 0.5824 | 0.3143 | 0.4507 | 0.5158 | 0.5163 | 0.3076 | 0.5267 | 0.2081 | 0.2767 | 0.1894 | 0.4279 | 5.5469 | 5.5436 |
| GSSG | 1.5355 | 1.7605 | 1.1745 | 1.2240 | 0.8148 | 0.4312 | NA | NA | NA | NA | NA | NA | 0.4277 | 0.0683 |
| guanidinoacetate | 0.2701 | 0.6212 | 0.2681 | 0.3784 | 2.0002 | 1.7152 | 0.6710 | 1.0121 | 0.6220 | 0.8560 | 0.4138 | 0.9277 | 2.1109 | 1.2736 |
| guanine | 0.0903 | 0.0822 | 0.0565 | 0.0668 | 3.0257 | 1.1009 | 3.0698 | 2.9975 | 2.0797 | 1.1001 | 1.9154 | 2.3510 | 0.1722 | 0.1630 |
| guanosine | 0.1958 | 0.7097 | 0.0893 | 0.2491 | 1.5333 | 0.7678 | NA | NA | NA | 0.5083 | NA | 0.7743 | 3.4497 | 3.2932 |
| histidine | 0.5437 | 1.0192 | 0.5957 | 1.0484 | 1.2251 | 1.5406 | 1.5578 | 0.6567 | 0.4059 | 0.5286 | 0.9768 | 1.4749 | 1.0668 | 0.8045 |
| homocitrulline | 0.7922 | 0.0605 | 2.0268 | 0.1233 | 1.1979 | 2.0012 | NA | NA | NA | NA | NA | NA | 0.3024 | 0.2558 |
| Homocysteine.sulfinic.acid | 0.4685 | 0.6205 | 0.6142 | 0.6448 | 0.9925 | 1.5099 | NA | NA | NA | NA | NA | NA | 2.1635 | 1.8844 |
| hydroxyproline_gammaALA | 2.4731 | 0.1345 | NA | NA | 0.9086 | 0.9122 | NA | NA | NA | NA | NA | NA | 1.5765 | 0.5676 |
| hypotaurine | NA | NA | NA | NA | 0.3200 | 0.5209 | NA | NA | NA | NA | NA | NA | 2.1831 | 2.7145 |
| hypoxanthine | 1.3691 | 1.0880 | 0.7432 | 0.9076 | 1.8044 | 0.6560 | 0.5906 | 0.6527 | 1.4520 | 0.2742 | 0.3656 | 0.8701 | 0.1965 | 1.3339 |
| INDOLE.3.ACETIC.ACID | 1.3562 | 0.6521 | 1.4386 | 0.4629 | 0.9418 | 1.0169 | 1.3204 | 0.6595 | 3.2195 | 1.2219 | 0.9056 | 0.6269 | 0.7024 | 0.6044 |
| indolelactate | 0.3009 | 0.1115 | 0.2219 | 0.2430 | 0.7679 | 1.1617 | NA | 2.7123 | NA | 1.2369 | 2.5366 | 2.5630 | 2.7777 | 3.1192 |
| inosine | 0.3436 | 0.5758 | 0.3429 | 0.4217 | 0.4490 | 0.2985 | NA | 0.6053 | NA | 2.1602 | NA | 1.8451 | 5.3001 | 3.6580 |
| isoleucine | 0.3219 | 0.5009 | 0.3037 | 0.3997 | 1.3014 | 2.0770 | 1.3030 | 1.3144 | 0.5685 | 0.5944 | 1.1309 | 1.1128 | 1.7914 | 1.6980 |
| kynurenine | 0.0955 | 0.0492 | 0.0664 | NA | 1.6609 | 2.4578 | NA | NA | NA | NA | NA | NA | 0.1806 | 0.2161 |
| lactic_acid | 1.1942 | 0.9827 | 1.2093 | 1.0765 | 1.1307 | 1.1781 | 0.3797 | 0.8402 | 0.2785 | 0.3492 | 0.3415 | 1.0673 | 0.8836 | 0.7909 |
| leucine | 0.2308 | 0.3813 | 0.2278 | 0.3527 | 1.7287 | 2.3932 | NA | NA | NA | NA | 0.7894 | 0.7296 | 1.1158 | 1.4350 |
| lysine | 0.7188 | 0.5114 | 0.5182 | 0.5830 | 2.0114 | 2.2171 | 0.2855 | 0.6569 | NA | 0.3193 | 0.3510 | 0.3736 | 0.6822 | 0.5904 |
| malate | 0.8625 | 0.7227 | 0.6701 | 0.6520 | 1.1848 | 1.1224 | 2.7168 | 2.3354 | 1.2119 | 1.4974 | 1.5876 | 1.9614 | 0.3148 | 0.4472 |
| methionine | 0.6352 | 0.8025 | 0.4104 | 0.7572 | 1.8467 | 2.5201 | 0.0708 | 0.0387 | 0.0180 | 0.0543 | 0.2407 | 0.0458 | 0.8829 | 0.7555 |
| Methionine.sulfoxide | 0.8115 | 1.3120 | 1.0329 | 1.0169 | 0.9367 | 1.1277 | 0.5392 | 2.4955 | 0.3993 | 0.8083 | 0.9246 | 1.8257 | 0.5992 | 0.3970 |
| methylthioadenosine | 0.7471 | 0.7827 | 0.7476 | 0.8128 | 1.6491 | 1.8637 | NA | NA | NA | NA | 0.1663 | NA | 0.2369 | 0.2178 |
| Mevalonate | 1.6726 | 1.6265 | 1.4904 | 1.7592 | 0.2930 | 0.3053 | NA | NA | NA | NA | NA | NA | 0.2357 | 0.1711 |
| myo.inositol | 1.5996 | 1.3331 | 1.8333 | 1.5257 | 0.4579 | 0.4708 | NA | NA | NA | NA | NA | NA | 0.0401 | 0.0547 |
| N.acetylglutamine | 1.7841 | 1.8363 | 1.6915 | 1.9005 | 0.0640 | 0.0733 | NA | NA | NA | NA | NA | NA | 0.1349 | 0.0970 |
| N.acetylornithine | 0.6904 | 0.7823 | 0.6031 | 0.7688 | 1.4874 | 1.6879 | NA | NA | NA | NA | NA | NA | 0.7775 | 0.5949 |
| N.acetylphenylalanine | 0.5485 | 0.9543 | 0.6103 | 0.9000 | 0.5281 | 0.6876 | 1.8437 | 1.6658 | NA | 0.6204 | 2.2549 | 0.4121 | 1.9386 | 3.0976 |
| N.alpha.acetyllysine | 1.3152 | 1.1445 | 1.1960 | 1.2812 | 0.7196 | 0.9477 | NA | NA | NA | NA | NA | NA | 0.5368 | 0.4213 |
| niacinamide | 1.2902 | 1.4917 | 2.2232 | 2.6788 | 0.2195 | 0.2374 | 0.1772 | 0.3242 | 0.2550 | 0.2740 | 0.2754 | 0.3352 | 0.2939 | 0.3757 |
| O.phosphoethanolamine | 1.5732 | 1.2736 | 1.1441 | 1.1265 | 0.9245 | 0.7799 | NA | NA | NA | NA | NA | NA | 0.0021 | 0.0042 |
| palmitate | 0.3495 | 0.3556 | 0.6279 | 0.1528 | 0.0965 | 0.1112 | 0.9504 | 2.4248 | 4.5098 | 8.6992 | 6.9787 | 2.4419 | 0.8232 | 0.6835 |
| p.aminobenzoate | 0.1470 | 0.3291 | 0.3752 | 0.1922 | 1.1934 | 1.5432 | NA | NA | NA | NA | NA | NA | 1.4273 | 1.2844 |
| Pantothenate | 0.4407 | 0.2107 | 0.4537 | 0.1510 | 2.3898 | 2.7564 | NA | NA | NA | NA | NA | 0.1589 | 0.0219 | 0.0213 |
| phenylalanine | 0.3623 | 0.7783 | 0.3436 | 0.6733 | 1.6076 | 2.1918 | 0.6542 | 0.5138 | 0.3996 | 0.3293 | 0.6815 | 0.7699 | 1.1932 | 1.3189 |
| phosphocholine | 0.9369 | 0.9128 | 0.8506 | 0.7946 | 1.9888 | 1.3522 | 0.9877 | 0.4781 | 1.9940 | 0.8227 | 0.6203 | 0.3108 | 0.0348 | 0.0160 |
| phosphocreatine | 1.7456 | 1.3016 | 1.5554 | 1.5860 | 0.1453 | 0.1037 | NA | NA | NA | NA | NA | NA | NA | NA |
| Pipecolate | 0.1213 | 0.1321 | 0.1558 | 0.0948 | 1.7639 | 2.3735 | NA | NA | NA | NA | NA | NA | 1.7353 | 1.4791 |
| proline | 0.0659 | 0.1320 | 0.0516 | 0.0719 | 2.2894 | 2.8981 | 1.1256 | 1.2645 | 0.5111 | 0.5829 | 0.6534 | 0.9716 | 1.0656 | 0.7687 |
| propionylcarnitine | 0.0788 | 0.1082 | 0.0886 | 0.0849 | 1.9949 | 2.4253 | NA | NA | NA | NA | NA | NA | 0.7054 | 0.6920 |
| pseudouridine | 1.4209 | 0.7447 | 1.3870 | 0.9125 | 1.2535 | 1.6371 | NA | 0.0339 | NA | 0.1185 | 0.0925 | 0.0388 | 0.4029 | 0.2986 |
| pyruvate | 0.6614 | 0.1766 | 0.7390 | 0.4402 | 1.5111 | 2.1007 | NA | NA | NA | NA | NA | NA | 0.3022 | 0.4030 |
| quinolinic_acid | 0.0599 | 0.0471 | NA | 0.1809 | 1.5232 | 1.7789 | NA | NA | NA | NA | NA | NA | 0.0360 | 0.0649 |
| S.Adenosyl.L.methionine | 0.6364 | 0.6716 | 0.5144 | 0.5378 | 1.7326 | 2.1389 | NA | NA | NA | NA | NA | NA | 0.0462 | 0.0775 |
| sarcosine | 0.9083 | 1.0209 | 1.0120 | 1.0090 | 1.2941 | 1.4792 | 0.3300 | 0.3611 | NA | 0.3165 | NA | 0.5057 | 0.7579 | 0.6519 |
| succinate | 0.2366 | 0.3039 | 0.3191 | 0.3158 | 0.2164 | 0.1911 | 4.9420 | 6.1119 | 7.8315 | 2.5096 | 3.1217 | 4.3500 | 0.0881 | 0.1091 |
| taurine | 0.8554 | 1.0420 | 0.8317 | 1.2221 | 1.1877 | 1.3358 | 0.3481 | 0.4814 | 0.3502 | 1.3731 | 0.5343 | 0.3594 | 1.1763 | 0.8893 |
| threonine | 1.7731 | 0.6940 | 1.3571 | 0.6371 | 0.9574 | 1.0512 | NA | NA | NA | NA | NA | NA | 0.6235 | 0.4326 |
| thymidine | 1.4261 | 0.7929 | 1.8486 | 1.0763 | 0.8125 | 0.9701 | 0.3696 | NA | NA | NA | NA | NA | 0.3056 | 0.2654 |
| THYMINE | 1.3327 | 0.7113 | 1.8968 | 0.9635 | 0.9240 | 1.0650 | NA | NA | NA | NA | NA | NA | 0.3581 | 0.3093 |
| tryptophan | 0.5290 | 0.4396 | 0.4715 | 0.3679 | 1.5530 | 2.0105 | 0.1165 | 0.2020 | 0.0375 | NA | 0.2614 | 0.2191 | 2.1689 | 2.3884 |
| tyrosine | 0.3481 | 1.2277 | 0.2444 | 0.9146 | 1.2251 | 1.7102 | 0.7718 | 0.5431 | 0.4229 | 0.3308 | 0.6387 | 0.6471 | 1.6826 | 1.8324 |
| UMP | 0.1527 | 0.3060 | 0.1102 | 0.1299 | 2.3502 | 1.3071 | NA | NA | NA | NA | NA | NA | 0.0423 | 0.0779 |
| uracil | 1.1003 | 1.0067 | 1.4103 | 0.8749 | 1.5087 | 0.8188 | NA | NA | NA | NA | NA | NA | 0.2066 | 0.1902 |
| Ureidosuccinic_acid | 0.1933 | 0.2623 | 0.1603 | 0.1985 | 2.3175 | 1.9856 | NA | NA | NA | NA | NA | NA | 0.8135 | 0.5593 |
| uridine | 0.8891 | 0.9212 | 0.9570 | 0.8610 | 2.2700 | 0.6285 | 0.1555 | 0.1505 | NA | 0.0951 | NA | NA | 0.8253 | 0.9713 |
| valine | 0.2514 | 0.3090 | NA | 0.3734 | 1.4976 | 1.7790 | 2.1508 | NA | NA | NA | NA | NA | 1.2513 | 1.1139 |
| X1.methylnicotinamide | 1.1075 | 0.7315 | 1.6811 | 1.3365 | 0.6456 | 0.8700 | NA | NA | NA | NA | NA | NA | 0.6110 | 0.8867 |
| X2.hydroxybutyric_acid | 1.7444 | 1.2248 | 1.1104 | 1.5620 | 0.4731 | 0.4230 | 1.2572 | NA | NA | 0.4885 | NA | 1.1730 | 0.6890 | 0.8282 |
| X2.hydroxyglutarate | 0.3053 | 0.3869 | 0.5706 | 0.3737 | 0.1640 | 0.1837 | 6.1675 | 4.7583 | 4.0156 | 4.5490 | 3.8775 | 3.9126 | 0.0889 | 0.1287 |
| X3.hydroxybutyric_acid | 1.0125 | 0.9873 | 0.9206 | 0.8158 | 0.6576 | 0.6471 | NA | NA | NA | NA | NA | NA | 1.6631 | 2.6027 |
| X3.hydroxyisobutyric_acid | 1.4263 | 1.2035 | 1.1592 | 1.1177 | 0.7972 | 0.9684 | NA | NA | NA | NA | NA | NA | 0.3799 | 0.3927 |
| X3.methyl.2.oxopentanoic_acid | 0.7633 | 0.7650 | 0.9217 | 0.8061 | 1.4743 | 1.7651 | NA | NA | NA | 0.4999 | NA | NA | 0.3170 | 0.3222 |
| X3.ureidopropionate | 1.4351 | 1.2455 | 1.6095 | 1.4354 | 0.6854 | 0.5798 | NA | NA | NA | 0.0782 | 0.1569 | NA | 1.0746 | 0.1937 |
| xanthine | 1.0843 | 1.3256 | 0.9887 | 1.0493 | 0.1723 | 0.1508 | 0.6275 | 0.5699 | 0.3811 | 0.5642 | NA | 0.6197 | 2.4178 | 3.9973 |
| xanthosine | NA | NA | NA | NA | 0.1263 | 0.1289 | NA | NA | NA | NA | NA | NA | 3.1738 | 3.1883 |
Factors:
| F1 | Sample type:Adult CSF | Storage condition:Fresh | Sex:Female |
| F2 | Sample type:Adult CSF | Storage condition:Fresh | Sex:Male |
| F3 | Sample type:Adult CSF | Storage condition:Frozen | Sex:Female |
| F4 | Sample type:Adult CSF | Storage condition:Frozen | Sex:Male |
| F5 | Sample type:Embryonic CSF | Storage condition:Fresh | Sex:Embryo |
| F6 | Sample type:Embryonic CSF | Storage condition:Frozen | Sex:Embryo |
| F7 | Sample type:Mock | Storage condition:Fresh | Sex:Embryo |
| F8 | Sample type:Mock | Storage condition:Fresh | Sex:Female |
| F9 | Sample type:Mock | Storage condition:Fresh | Sex:Male |
| F10 | Sample type:Mock | Storage condition:Frozen | Sex:Embryo |
| F11 | Sample type:Mock | Storage condition:Frozen | Sex:Female |
| F12 | Sample type:Mock | Storage condition:Frozen | Sex:Male |
| F13 | Sample type:Serum | Storage condition:Fresh | Sex:Male |
| F14 | Sample type:Serum | Storage condition:Frozen | Sex:Male |
