Data for (Study ST003076)

(Analysis AN005034)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
10-Hydroxydecanoate 1.1400 0.7201
1-Methylnicotinamide 1.1552 0.6896
2-Hydroxybutyrate 1.1202 0.7596
2-Hydroxyglutarate 1.1473 0.7055
2-Methylmaleate 1.0910 0.8181
2-Phosphoglycerate/3-Phosphoglycerate 1.0532 0.8937
3-(4-Hydroxyphenyl)Pyruvate 1.0961 0.8077
3-Hydroxybutanoate 1.0666 0.8667
3-Hydroxybutyrylcarnitine 1.2592 0.4816
3-Hydroxyhexadecanoylcarnitine 1.1985 0.6029
3-Hydroxyhexadecenoylcarnitine 1.2416 0.5168
3-Hydroxymethylglutarate 1.0763 0.8475
3-Hydroxy-N6N6N6-Trimethyl-L-Lysine 1.1395 0.7210
3-Methyl-2-Oxobutanoate 1.0533 0.8933
3-Methyl-2-Oxovalerate/Ketoleucine 1.0460 0.9080
3-Methyl-L-Histidine/1-Methyl-L-Histidine 1.0132 0.9735
4-Guanidinobutanoate 0.9871 1.0259
4-Imidazoleacetate 1.0171 0.9657
4-Pyridoxate 0.9450 1.1099
5-Hydroxyindoleacetate 0.7105 1.5791
5-Hydroxylysine 1.4773 0.0454
5-Hydroxytryptophan 0.7917 1.4167
6-Phosphogluconate 0.9668 1.0664
Acetoacetate 1.0101 0.9797
Acetylcholine 1.0754 0.8493
Acetyl-CoA 1.0279 0.9442
Adenine 1.0992 0.8015
Adenosine 1.1588 0.6823
Adenosine 5^-Diphosphate 1.0057 0.9886
Adenosine Diphosphate Ribose 1.1474 0.7051
Adenosine-Monophosphate 1.1058 0.7884
Adenosine Triphosphate 1.0789 0.8423
AICAR 1.1953 0.6095
Allantoin 1.1201 0.7598
Alpha-D-Glucose 1.1937 0.6126
Alpha-Linolenyl Carnitine/Gamma-Linolenyl Carnitine 1.1512 0.6976
Aminoisobutanoate/2-Aminoisobutyrate 0.9819 1.0361
Anserine 1.1471 0.7059
Arachidonic Acid 0.7190 1.5620
Arginine 0.8795 1.2410
Ascorbate 1.1340 0.7320
Asparagine 0.8824 1.2352
Aspartate 0.9909 1.0182
Azelate 0.9828 1.0344
Betaine 1.1162 0.7675
Beta-Nicotinamide Adenine Dinucleotide 1.0063 0.9874
Biotin 0.8975 1.2050
Butanoate 0.9712 1.0575
Butyryl Carnitine 1.0732 0.8536
Carnosine 1.0395 0.9210
Cdp-Ethanolamine 1.1073 0.7853
Chenodeoxycholate/Deoxycholate 0.9685 1.0629
Cholesterol Sulfate 1.1067 0.7865
Choline 1.0214 0.9572
Cis-Aconitate 1.1175 0.7650
Citicoline 1.1020 0.7959
Citrate/Isocitrate 1.0857 0.8286
Citrulline 1.0003 0.9995
Coenzyme A 1.1298 0.7404
Creatine 1.0675 0.8650
Creatinine 1.0662 0.8676
Cyclic AMP 1.0266 0.9467
Cys-Gly 1.0688 0.8624
Cystathionine 0.9551 1.0899
Cysteate 0.9324 1.1353
Cysteine 0.9455 1.1091
Cystine 0.8549 1.2902
Cytidine 0.8941 1.2118
Cytidine Monophosphate 1.0466 0.9068
Cytosine 0.8941 1.2117
Decanoate 1.0487 0.9026
Decenoyl Carnitine 1.1218 0.7565
Deoxyadenosine 1.1740 0.6520
Deoxycarnitine 1.1400 0.7200
Deoxycytidine 0.7252 1.5496
Deoxyuridine 0.9980 1.0041
D-Erythrose 4-Phosphate 0.9872 1.0257
Desmosterol 0.8433 1.3135
Dihydrobiopterin 1.0083 0.9835
Dihydrouracil 0.8888 1.2223
Dihydroxyacetone Phosphate/Glyceraldehyde 3-Phosphate 1.1016 0.7969
Dimethylglycine 1.0253 0.9494
Docosahexaenoate 0.7287 1.5425
D-Ribose 5-Phosphate 1.1067 0.7867
D-Sedoheptulose 7-Phosphate 1.1279 0.7442
Eicosapentaenoate 0.7413 1.5175
Elaidate/Oleate/Petroselinate 0.8988 1.2024
Elaidic Carnitine/Vaccenyl Carnitine 1.0415 0.9170
Erythritol/Threitol 1.1277 0.7446
FAD 1.0881 0.8237
Fructose 6-Phosphate/Glucose 6-Phosphate/Glucose 1-Phosphate 1.1374 0.7252
Fructose Bisphosphate 0.9911 1.0178
Fumarate 1.0331 0.9338
Galactarate/Saccharate 1.2151 0.5697
Galactitol/Mannitol/Sorbitol 1.3343 0.3314
Gamma-Aminobutyrate 0.8948 1.2104
Gamma-Linolenate 0.9343 1.1315
Gluconate/Galactonate 1.0494 0.9012
Glucosamine 1.1440 0.7119
Glucosamine 6-Phosphate 1.1115 0.7770
Glucosamine 6-Sulfate 1.0863 0.8274
Glucuronate 0.9758 1.0484
Glutamate 1.0180 0.9640
Glutamine 0.9454 1.1092
Glutarate 1.0466 0.9068
Glutarylcarnitine 1.0393 0.9214
Glutathione Reduced 1.0592 0.8815
Glycerate 1.0325 0.9350
Glycerol 3-Phosphate 1.1164 0.7671
Glycerophosphocholine 1.0890 0.8220
Glycine 0.9785 1.0430
Glycochenodeoxycholate 0.1721 2.6558
GSSG 1.0985 0.8030
Guanidinoacetate 0.8764 1.2473
Guanine 0.8298 1.3404
Guanosine 1.0104 0.9791
Guanosine Diphosphate 0.9684 1.0632
Guanosine Monophosphate 1.0870 0.8260
Guanosine Triphosphate 1.2124 0.5752
Heptadecanoate 0.9086 1.1827
Heptadecanoyl Carnitine 0.9861 1.0279
Hippurate 1.2539 0.4922
Histamine 0.8395 1.3209
Histidine 0.8880 1.2240
Hypotaurine 0.9830 1.0340
Hypoxanthine 1.0895 0.8210
Indole-3-Pyruvate 1.1512 0.6976
Indoleacetaldehyde 0.7678 1.4644
Indoxyl Sulfate 1.1253 0.7493
Inosine 1.0906 0.8187
Inosine-Monophosphate 1.0257 0.9486
Isoleucine/Leucine 0.9100 1.1801
Itaconate 1.0976 0.8047
Kynurenine 1.1378 0.7243
Lactate 1.1365 0.7270
L-Alanine 0.9741 1.0518
Laurate 0.9835 1.0331
Lauroylcarnitine 1.0962 0.8075
L-Carnitine 1.1056 0.7888
Linoleate 0.7051 1.5899
Linoleyl Carnitine/Linoelaidyl Carnitine 1.1027 0.7947
L-Ornithine 0.8795 1.2409
L-Threonate 1.0674 0.8652
Lysine 0.8459 1.3081
Malate 1.0357 0.9286
Mesaconic Acid 1.1587 0.6825
Methionine 0.9044 1.1912
Methionine Sulfoxide 1.0051 0.9897
Methyl Galactoside/D-Pinitol 1.1729 0.6542
Methylguanidine 1.3065 0.3869
Methylimidazoleacetic Acid 0.8825 1.2351
Methylthioadenosine 1.2233 0.5534
Myoinositol 1.0634 0.8732
Myristate 0.9351 1.1299
N6N6N6-Trimethyl-L-Lysine 0.9939 1.0122
N-Acetylalanine 0.9217 1.1565
N-Acetylasparagine 0.9424 1.1151
N-Acetylaspartate 1.0876 0.8248
N-Acetylgalactosamine 1.0526 0.8948
N-Acetylglucosamine 1.0526 0.8948
N-Acetylglutamate 1.0854 0.8292
N-Acetylmethionine 0.7533 1.4933
N-Acetylneuraminate 0.9849 1.0302
N-Acetyltryptophan 0.9554 1.0891
NADH 1.2216 0.5568
NADP 0.7511 1.4977
N-Glycolylneuraminic Acid 1.0871 0.8259
Nicotinamide 1.1712 0.6576
Nicotinamide Mononucleotide 0.9175 1.1650
N,N-Dimethylarginine 1.0732 0.8536
N(Omega)-(L-Arginino)Succinate 0.9521 1.0957
O-Acetylcarnitine 1.1380 0.7240
Oleoyl-Glycerol 0.7325 1.5350
Omega-Hydroxydodecanoate 1.1517 0.6966
O-Phosphoethanolamine 1.1138 0.7724
Ophthalmate 0.8166 1.3668
Oxoglutarate 1.1477 0.7047
Oxoproline 1.0158 0.9683
Palmitate 0.9788 1.0423
Palmitoleate 0.9522 1.0957
Palmitoylcarnitine 1.0327 0.9346
Pantothenate 0.9263 1.1475
Pentadecanoylcarnitine 1.0076 0.9847
Phenylacetic Acid 0.9980 1.0040
Phenylalanine 0.8985 1.2029
Phosphocreatine 1.1486 0.7028
Phosphoenolpyruvate 1.0283 0.9434
Phosphorylcholine 1.1147 0.7705
Pipecolate 1.0293 0.9414
Porphobilinogen 0.9171 1.1657
Proline 0.9322 1.1355
Propionyl-Carnitine 0.9948 1.0105
Pyridoxal 0.9839 1.0321
Pyruvate 1.0326 0.9348
Quinoline 0.9068 1.1865
Raffinose 1.3369 0.3263
Ribitol/Xylitol/Arabitol 1.0761 0.8477
Riboflavin 0.6107 1.7786
Ribose 1,5-Bisphosphate 0.9633 1.0734
(R)-S-Lactoylglutathionate 0.1944 2.6112
S-Adenosylhomocysteine 1.0041 0.9918
S-Adenosylmethionine 1.0609 0.8783
Serine 0.8985 1.2030
Serotonin 1.1316 0.7368
Sphingomyelin 1.1143 0.7714
Stearate 1.0279 0.9442
Stearoylcarnitine 1.0265 0.9471
Succinate 0.9855 1.0291
Succinate Semialdehyde 1.0922 0.8157
Succinylcarnitine 1.1428 0.7144
Taurine 1.0616 0.8768
Taurochenodesoxycholic Acid 0.5428 1.9144
Tetradecanoyl Carnitine(Myristoyl Carnitine) 1.0888 0.8224
Tetradecenoyl Carnitine 1.0999 0.8002
Thiamine 1.1585 0.6830
Thiamine Pyrophosphate 1.0917 0.8165
Threonine 0.9214 1.1573
Thymidine 1.1730 0.6540
Thymine 1.1428 0.7144
Tiglyl Carnitine 1.1313 0.7373
Tma-Oxide 1.0939 0.8122
Trans-4-Hydroxy-L-Proline 1.0325 0.9350
Trans-Hexadec-2-Enoyl Carnitine 1.1091 0.7819
Trigonelline 1.0991 0.8018
Tryptophan 0.8545 1.2910
Tyrosine 0.8486 1.3029
Uracil 1.0745 0.8510
Urate 1.0434 0.9133
Ureidopropionate 1.1985 0.6030
Uridine 1.0317 0.9366
Uridine 5^-Diphosphate 1.0312 0.9375
Uridine Diphosphate Glucose 1.0916 0.8169
Uridine Diphosphate Glucuronic Acid 1.0201 0.9598
Uridine Diphosphate-N-Acetylglucosamine 1.0954 0.8092
Uridine Monophosphate 1.1290 0.7420
Uridine Triphosphate 1.1874 0.6253
Valine 0.8872 1.2255
Xanthine 1.0136 0.9728
Xanthosine 0.9471 1.1059
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Factors:

F1Treatment:metformin
F2Treatment:water
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