Data for (Study ST003079)
(Analysis AN005037)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|
| "1,4-BUTANEDIAMINE" | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| "1,4-BUTANEDIAMINE_13C4" | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| alanine | 1.0051 | 1.6641 | 1.1009 | 0.8953 | 0.7944 | 1.4439 | 1.6582 | 0.6202 | 0.6005 | 0.0026 |
| alanine-13C3-15N | 1.2631 | 1.4327 | 1.1253 | 0.2369 | 0.2838 | 0.1706 | 0.1753 | 0.9885 | 0.9815 | 2.5895 |
| Alpha-Ketoglutarate | NA | 1.1651 | NA | 0.8727 | 1.2891 | NA | 0.3461 | NA | NA | NA |
| "ALPHA-KETOGLUTARIC ACID_1,2,3,4- 13C4" | NA | 0.6291 | NA | 1.1883 | 1.6329 | 0.9445 | NA | NA | NA | NA |
| arginine | 1.5178 | 2.4273 | 2.0290 | 0.7491 | 0.7147 | 0.0111 | 0.0098 | 1.1694 | 1.1910 | 0.0039 |
| arginine-13C6-15N4 | 1.4570 | 0.8948 | 1.1856 | 0.2332 | 0.2337 | 0.0802 | 0.0181 | 1.8173 | 1.7596 | 2.0325 |
| aspartate | 0.0200 | 0.0262 | 0.0214 | 3.5917 | 3.6777 | 1.1358 | 1.5647 | 0.2055 | 0.2457 | 0.0071 |
| aspartate-13C6-15N4 | 1.4944 | 2.4894 | 1.5067 | 0.3433 | 0.3422 | 0.1133 | 0.0813 | 0.8072 | 0.8042 | 1.0723 |
| citrate | 1.6327 | 2.5273 | 1.7706 | 0.6044 | 0.4185 | 0.4344 | 0.4346 | 0.8669 | 0.9507 | 0.0151 |
| "CITRIC ACID_1,5,6-CARBOXYL-13C3" | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| creatinine | 1.0722 | 2.2410 | 1.4155 | 0.3908 | 0.3070 | 0.4696 | 0.9223 | 0.7634 | 0.9173 | NA |
| CREATININE_N-METHYL-D3 | 0.6208 | 1.2284 | 0.6924 | 1.0974 | 1.0902 | 0.9189 | 1.0440 | 1.4599 | 1.0896 | 0.6572 |
| cysteine_13C3_15N1 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| cysteine_unc | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| cystine | 0.9016 | 1.4404 | 1.0999 | 0.0167 | 0.0249 | 0.0113 | NA | 2.1831 | 1.2499 | NA |
| cystine-13C6-15N2 | 1.7096 | 0.8903 | 1.6650 | 0.0359 | 0.0404 | 0.0529 | NA | 1.2009 | 1.1458 | 1.3798 |
| "ETHANOLAMINE_1,1,2,2-D4" | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| fumarate | 0.2278 | 0.3683 | 0.2639 | 1.1276 | 0.9636 | 2.4351 | 2.9023 | 0.6407 | 0.5011 | 0.0055 |
| FUMARIC ACID_13C4 | NA | NA | NA | NA | NA | NA | NA | 0.9876 | 1.0207 | NA |
| glutamate | 0.0304 | 0.0276 | 0.0398 | 3.5662 | 3.3041 | 1.4319 | 1.8368 | 0.2226 | 0.2095 | 0.0051 |
| "glutamate-13C5,15N" | 1.5933 | 2.5420 | 1.5918 | 0.2359 | 0.2510 | 0.1220 | 0.0652 | 0.8837 | 0.8983 | 1.0663 |
| glycine | 0.2284 | 0.6669 | 0.2272 | 2.0506 | 1.7529 | 1.8447 | 3.0978 | 0.1536 | 0.1767 | 0.0308 |
| glycine_13C2-15N | 1.1005 | 1.6035 | 0.9645 | NA | NA | NA | NA | 0.5797 | 0.5162 | 0.9027 |
| guanosine | 0.1372 | 0.0846 | 0.1781 | 0.6131 | 0.4272 | 2.4878 | 5.3492 | 0.1094 | 0.2577 | NA |
| GUANOSINE_15N5 | NA | NA | NA | NA | 1.1246 | 0.8754 | NA | NA | NA | NA |
| histidine | 0.8620 | 1.0124 | 1.4661 | 0.5484 | 0.5943 | 1.9378 | 2.8218 | 0.3992 | 0.5258 | 0.0027 |
| histidine-13C6-15N3 | 1.6247 | 0.7503 | 1.7652 | 0.1306 | 0.1500 | 0.1030 | 0.0951 | 1.8348 | 2.0636 | 1.6254 |
| hypoxanthine | 0.4391 | 0.4735 | 0.6729 | 1.1347 | 0.8711 | 1.9827 | 3.4842 | 0.7379 | 0.9422 | 0.0008 |
| HYPOXANTHINE_13C5 | 0.2070 | 0.8627 | 0.5018 | 0.8983 | 0.9823 | 1.2667 | 1.0560 | 1.7110 | 2.0040 | 0.8125 |
| INDOLE-3-ACETIC ACID | 0.3254 | 2.0053 | 1.0296 | 0.0499 | 0.0366 | 0.0919 | 0.1085 | 2.6312 | 2.6553 | 0.0901 |
| INDOLE-3-ACETIC ACID_PHENYL-13C6 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| isoleucine | 0.7940 | 1.4474 | 2.8283 | 0.4170 | 0.5050 | 0.9521 | 0.9882 | 0.8359 | 1.1000 | 0.0076 |
| Isoleucine-13C6-15N | 1.2982 | 1.1908 | 1.5130 | 0.1720 | 0.1978 | 0.1554 | 0.0856 | 1.5179 | 1.4038 | 2.1098 |
| L-ALANINE_13C3 | 1.2625 | 1.4328 | 1.1254 | 0.2369 | 0.2838 | 0.1706 | 0.1753 | 0.9886 | 0.9816 | 2.5897 |
| leucine | 0.9224 | 2.2764 | 1.3283 | 0.5891 | 0.5957 | 1.0048 | 1.5240 | 0.3774 | 0.5317 | 0.0019 |
| leucine-13C6-15N | 1.5001 | 2.1506 | 1.4035 | 0.2601 | 0.2645 | 0.2122 | 0.2290 | 1.0068 | 1.0480 | 1.2789 |
| L-LEUCINE_13C6 | 0.3465 | 1.2987 | 0.5182 | 0.9323 | 1.0235 | 0.7114 | 0.7262 | 1.5090 | 1.5157 | 0.8116 |
| L-PHENYLALANINE_RING-13C6 | 0.5554 | 1.2175 | 0.6056 | 0.8375 | 0.8345 | 0.7959 | 0.7717 | 1.6885 | 1.8014 | 0.9075 |
| L-TRYPTOPHAN_13C11 | 0.5984 | 1.3818 | 0.6346 | 0.9453 | 0.9770 | 0.7497 | 0.6601 | 1.6297 | 1.6607 | 0.7129 |
| L-TYROSINE_RING-13C6 | 0.5541 | 1.1242 | 0.4979 | 0.8591 | 0.8824 | 0.7299 | 0.6869 | 1.8267 | 1.7988 | 1.0190 |
| lysine | 1.3524 | 2.8389 | 1.7870 | 0.3433 | 0.3023 | 0.4680 | 0.6039 | 0.4668 | 0.4971 | 0.0007 |
| lysine-13C6-15N2 | 1.8668 | 1.7687 | 1.7430 | 0.1798 | 0.1846 | 0.1425 | 0.1275 | 1.2575 | 1.2879 | 1.1261 |
| methionine | 0.2035 | 2.5591 | 0.7150 | 0.8561 | 1.0968 | 1.0173 | 1.5918 | 0.0708 | 0.1121 | NA |
| methionine-13C5-15N | 0.8394 | 2.5019 | 1.6304 | 0.8381 | 0.7821 | 0.6892 | 0.5694 | 0.7273 | 0.4030 | 0.0358 |
| niacinamide | 0.0719 | 0.0934 | 0.0693 | 0.8590 | 0.6854 | 3.3606 | 4.1249 | 0.2019 | 0.1075 | 0.0004 |
| NICOTINAMIDE_13C6 | 0.4348 | 0.4906 | 0.7843 | 0.3326 | 0.4026 | 0.0715 | NA | 2.7980 | 2.8115 | 0.8539 |
| palmitate | 0.4701 | 0.5041 | 0.4816 | 0.3060 | 0.2113 | 1.4375 | 1.9940 | 1.4906 | 2.6702 | 0.0041 |
| PALMITATE_U-13C16 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| phenylalanine | 1.2198 | 2.3178 | 1.6305 | 0.5645 | 0.5623 | 0.8380 | 1.1808 | 0.3602 | 0.4975 | 0.0032 |
| phenylalanine-13C9-15N | 1.5588 | 1.7161 | 1.6274 | 0.2166 | 0.2168 | 0.1879 | 0.1838 | 1.1978 | 1.2059 | 1.4789 |
| proline | 1.4562 | 2.2857 | 1.8471 | 1.0706 | 0.9611 | 0.6759 | 0.8717 | 0.2870 | 0.4125 | 0.0049 |
| proline-13C5-15N | 1.7074 | 1.2393 | 1.5716 | 0.1992 | 0.2060 | 0.1967 | 0.1763 | 1.4287 | 1.2923 | 1.7086 |
| pyruvate | 0.2211 | 0.0094 | NA | 0.5881 | 0.3754 | 1.7258 | 2.1699 | NA | NA | NA |
| PYRUVATE_13C3 | NA | NA | NA | 0.8705 | 0.9356 | 1.0930 | 1.1101 | NA | NA | NA |
| serine | 1.0258 | 2.8443 | 1.7024 | 0.9599 | 1.1291 | 0.4676 | 0.9175 | 0.1962 | 0.3606 | 0.0178 |
| serine-13C3-15N | 1.6869 | 1.6781 | 1.4552 | 0.0720 | 0.0622 | 0.0828 | NA | 0.8560 | 0.8237 | 1.1977 |
| SODIUM PALMITATE_U-13C16 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| threonine | 1.3604 | 1.6603 | 1.7898 | 0.8148 | 0.7891 | 0.7400 | 0.9509 | 0.7945 | 0.8608 | 0.0144 |
| threonine-13C4-15N | 1.7344 | 0.9969 | 1.5445 | 0.1243 | 0.1272 | 0.0998 | 0.0926 | 1.0415 | 0.9540 | 2.7823 |
| THYMINE | 1.6044 | 2.6989 | 1.7239 | 0.5796 | 0.4385 | 0.1587 | 0.2739 | 0.4233 | 0.5428 | 0.0851 |
| "THYMINE_1,3-15N2" | 0.7889 | 1.4339 | 0.8949 | 0.7877 | 0.7856 | 0.8100 | 0.8005 | 1.3971 | 1.3550 | 0.8249 |
| tryptophan | 0.6468 | 2.5367 | 1.1418 | 0.5563 | 0.5575 | 0.7009 | 0.9655 | 0.9203 | 1.1507 | 0.0004 |
| tyrosine | 0.8952 | 2.3021 | 1.3569 | 0.6900 | 0.7523 | 1.0898 | 1.6325 | 0.4451 | 0.6633 | 0.0037 |
| tyrosine-13C9-15N | 1.5059 | 1.6188 | 1.3606 | 0.2225 | 0.2292 | 0.1664 | 0.1592 | 1.3546 | 1.2787 | 1.6118 |
| valine | 0.9565 | 2.2188 | 1.2482 | 0.6637 | 0.6142 | 0.8602 | 1.2159 | 0.5387 | 0.5733 | 0.0074 |
| valine-13C5-15N | 1.4848 | 1.3835 | 1.3767 | 0.2362 | 0.2379 | 0.2008 | 0.1887 | 1.3416 | 1.2995 | 1.8273 |
Factors:
| F1 | Sample source:Embryonic CSF | Maternal Treatment (injection):PolyIC | Developmental Timepoint:E12.5 | Collection Time:3 Hrs |
| F2 | Sample source:Embryonic CSF | Maternal Treatment (injection):PolyIC | Developmental Timepoint:E14.5 | Collection Time:48 Hrs |
| F3 | Sample source:Embryonic CSF | Maternal Treatment (injection):saline | Developmental Timepoint:E12.5 | Collection Time:3 Hrs |
| F4 | Sample source:Embyronic Liver | Maternal Treatment (injection):PolyIC | Developmental Timepoint:E12.5 | Collection Time:3 Hrs |
| F5 | Sample source:Embyronic Liver | Maternal Treatment (injection):saline | Developmental Timepoint:E12.5 | Collection Time:3 Hrs |
| F6 | Sample source:Maternal Liver | Maternal Treatment (injection):PolyIC | Developmental Timepoint:E12.5 | Collection Time:3 Hrs |
| F7 | Sample source:Maternal Liver | Maternal Treatment (injection):saline | Developmental Timepoint:E12.5 | Collection Time:3 Hrs |
| F8 | Sample source:maternal serum | Maternal Treatment (injection):PolyIC | Developmental Timepoint:E12.5 | Collection Time:3 Hrs |
| F9 | Sample source:maternal serum | Maternal Treatment (injection):saline | Developmental Timepoint:E12.5 | Collection Time:3 Hrs |
| F10 | Sample source:mock | Maternal Treatment (injection):N/A | Developmental Timepoint:N/A | Collection Time:N/A |
