Data for (Study ST003081)
(Analysis AN005039)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| "1,4-BUTANEDIAMINE" | NA | NA | NA | NA |
| "1,4-BUTANEDIAMINE_13C4" | NA | NA | NA | NA |
| 1-methylnicotinamide | NA | NA | NA | NA |
| "2,3-BPG_unc" | NA | NA | NA | NA |
| 2-aminobutyric_acid | NA | NA | NA | NA |
| 2-hydroxybutyric_acid | 1.3657 | 1.5294 | 0.1225 | 0.9030 |
| 2-hydroxyglutarate | 1.2671 | 1.2245 | 0.7551 | 0.8392 |
| 2-oxoadipate | NA | NA | NA | NA |
| 2-oxobutyric_acid_unc | NA | NA | NA | NA |
| 3-hydroxybutyric_acid | 0.9967 | 1.3898 | NA | 0.7418 |
| 3-hydroxyisobutyric_acid | NA | NA | NA | NA |
| 3-methyl-2-oxopentanoic_acid | 1.1511 | 1.2807 | NA | 0.7373 |
| 3-phosphoglycerate | 1.1770 | 1.2834 | NA | 0.6671 |
| 3-ureidopropionate | 1.2616 | 1.2551 | 0.0062 | 0.8648 |
| 4-Hydroxyphenylpyruvic acid | NA | NA | NA | NA |
| "5,10-CH2-H4PteGlu" | NA | NA | NA | NA |
| "5,10-CH=H4PteGlu" | NA | NA | NA | NA |
| 5_10-CHO-H4PteGlu | NA | NA | NA | NA |
| 5-CH3-H4PteGlu | 1.3583 | 1.4756 | 0.0389 | 0.8242 |
| 6-phosphogluconate | NA | NA | NA | NA |
| acetoacetate | NA | NA | NA | NA |
| acetylcarnitine | 1.8994 | 2.1365 | 0.0018 | 1.2908 |
| Acetyl CoA | NA | NA | NA | NA |
| adenine | 1.1516 | 1.2133 | NA | 1.0114 |
| adenosine | NA | NA | NA | NA |
| ADP | NA | NA | NA | NA |
| ADP-ribose | NA | NA | NA | NA |
| AICAR | NA | NA | NA | NA |
| alanine | 1.9655 | 1.9754 | 0.0404 | 1.3431 |
| alanine-13C3-15N | 0.4004 | 0.4074 | 4.0181 | 0.3521 |
| allantoin | 1.0267 | 1.2847 | NA | 0.7969 |
| Alpha-Ketoglutarate | 1.1371 | 1.3042 | 0.5392 | 0.9590 |
| "ALPHA-KETOGLUTARIC ACID_1,2,3,4- 13C4" | 1.0205 | 1.1610 | 1.1454 | 0.9759 |
| alpha-keto-isovalerate | 1.3345 | 1.5403 | 0.2041 | 0.8705 |
| Alpha-Lipoic Acid_unc | 1.2401 | 1.3209 | 1.1538 | 0.7557 |
| amidoadipate | 1.2137 | 1.5105 | 0.3490 | 0.8784 |
| AMP | 1.8563 | 1.6344 | NA | 1.1288 |
| anserine | 1.0829 | 1.2191 | NA | 0.8125 |
| anthranilic_acid | NA | NA | NA | NA |
| arginine | 1.8364 | 2.0292 | 0.0022 | 1.3933 |
| arginine-13C6-15N4 | NA | NA | NA | NA |
| argininosuccinate_unc | 1.0935 | 1.2011 | NA | 0.8192 |
| ascorbate_unc | 1.5341 | 1.2150 | 0.4089 | 1.0487 |
| asparagine | 1.2049 | 1.3871 | 0.0103 | 0.8044 |
| aspartate | 1.2503 | 1.4505 | 0.7050 | 1.0156 |
| aspartate-13C6-15N4 | NA | NA | NA | NA |
| asymmetric dimethylarginine | 1.5264 | 1.5909 | 0.0001 | 1.0094 |
| ATP | NA | NA | NA | NA |
| beta-alanine | NA | NA | NA | 1.0000 |
| betaine | 1.5035 | 1.3819 | 0.0005 | 0.9934 |
| biotin | 1.2049 | 1.1977 | NA | 0.7657 |
| Butyrylcarnitine | 1.4530 | 1.6956 | 0.0012 | 0.9754 |
| C5 Carnitines | 1.1083 | 1.4784 | NA | 0.7934 |
| cAMP | NA | NA | NA | NA |
| carnitine | 2.0309 | 1.9923 | 0.0006 | 1.3224 |
| carnosine | 1.0653 | 1.2311 | NA | 0.8133 |
| CDP | NA | NA | NA | NA |
| CDP-choline | NA | NA | NA | NA |
| Chenodeoxycholic acid | 1.8769 | 0.9452 | NA | 0.3972 |
| Cholic acid | 2.1764 | 0.7490 | NA | 0.5791 |
| choline | 1.5577 | 1.2735 | 0.0025 | 1.4085 |
| cis-aconitate | 1.2751 | 1.4206 | 0.0118 | 0.9115 |
| citrate | 1.5588 | 1.5528 | 0.0058 | 1.0157 |
| "CITRIC ACID_1,5,6-CARBOXYL-13C3" | NA | NA | NA | NA |
| citrulline | 1.3352 | 1.5912 | 0.0095 | 0.9335 |
| CMP | NA | 1.0000 | NA | NA |
| CoA-Ellmans_unc | NA | NA | NA | NA |
| Coenzyme A | NA | NA | NA | NA |
| creatine | 1.9716 | 1.9626 | 0.0026 | 1.3680 |
| creatinine | 1.8012 | 1.8939 | 0.0241 | 1.1615 |
| CREATININE_N-METHYL-D3 | 1.6084 | 1.5651 | 1.6423 | 0.9965 |
| CTP | NA | NA | NA | NA |
| Cys_Ell | NA | NA | NA | NA |
| Cys_Gly_Ell | NA | NA | NA | NA |
| cystathionine | 0.8212 | 1.3245 | 0.2676 | 1.7597 |
| cysteic_acid | NA | NA | NA | NA |
| cysteine_13C3_15N1 | NA | NA | NA | NA |
| cysteine-glycine | NA | NA | NA | NA |
| cysteine_unc | NA | NA | NA | NA |
| cystine | 1.2020 | 1.2310 | NA | 0.7450 |
| cystine-13C6-15N2 | NA | NA | NA | NA |
| cytidine | 1.2826 | 1.2741 | 0.0078 | 0.8414 |
| cytosine | 1.3833 | 1.3799 | 0.0179 | 0.8824 |
| dATP | NA | NA | NA | NA |
| dCTP | NA | NA | NA | NA |
| dCytidine | 1.3540 | 1.2527 | 0.0422 | 0.8141 |
| Deoxycholic acid | 1.8762 | 0.9458 | NA | 0.3970 |
| dihydroorotate | NA | NA | NA | NA |
| dihydroxyacetone_phosphate | NA | NA | NA | NA |
| dimethylglicine | 1.1705 | 1.2891 | NA | 0.7221 |
| dTMP | NA | NA | NA | NA |
| dTTP | NA | NA | NA | NA |
| dUMP | NA | NA | NA | NA |
| erythrose_4-phosphate_unc | NA | NA | NA | NA |
| "ETHANOLAMINE_1,1,2,2-D4" | NA | NA | NA | NA |
| F6P_G1P | 1.4014 | 1.4252 | NA | 0.8465 |
| FAD | NA | NA | NA | NA |
| folic_acid | NA | NA | NA | NA |
| formyl_methionine | 1.1310 | 1.2596 | NA | 0.7615 |
| fructose | NA | NA | NA | NA |
| "Fructose 1,6-bisphosphate" | 1.3135 | 1.1462 | NA | 0.7458 |
| fumarate | 1.3087 | 1.3994 | 0.3652 | 0.8968 |
| FUMARIC ACID_13C4 | 1.1313 | 1.1106 | 1.4027 | 0.6593 |
| gamma-aminobutyric_acid | NA | NA | NA | NA |
| gamma-glutamyl-alanine | 1.4762 | 1.6049 | 0.0737 | 0.9884 |
| GAR | NA | NA | NA | NA |
| GDP | NA | NA | NA | NA |
| glucose | 1.1497 | 1.6212 | 0.0449 | 0.9886 |
| Glucose 6-phosphate | 1.1561 | 1.4023 | NA | 0.6538 |
| glutamate | 1.6843 | 1.5370 | 0.8039 | 1.2284 |
| "glutamate-13C5,15N" | NA | NA | NA | NA |
| glutamine | 1.8137 | 1.9194 | 0.0053 | 1.3076 |
| glyceraldehyde_3-phosphate | NA | NA | NA | NA |
| glycerate | 1.4695 | 1.4669 | 1.3494 | 0.9458 |
| Glycerol 3-Phosphate | 1.0988 | 1.3263 | NA | 0.7330 |
| Glycerophosphocholine | 1.7859 | 2.1469 | 0.0237 | 1.3235 |
| glycine | 1.2535 | 1.4433 | 0.4775 | 0.8390 |
| glycine_13C2-15N | NA | NA | NA | NA |
| GMP | NA | NA | NA | NA |
| GSH | NA | NA | NA | NA |
| GSH-13C2_15N | NA | NA | NA | NA |
| GSH_13C2-15N-Ellmans | NA | NA | NA | NA |
| GSH_Ellmans | NA | NA | NA | NA |
| GSSG | 1.4809 | 1.5665 | NA | 1.0075 |
| GSSG-13C4_15N2 | NA | NA | NA | NA |
| GTP | NA | NA | NA | NA |
| guanidinoacetate | 1.3474 | 1.5628 | 0.0099 | 0.9476 |
| guanine | 1.5125 | 1.5384 | 0.0319 | 1.0401 |
| guanosine | NA | NA | NA | NA |
| GUANOSINE_15N5 | NA | NA | NA | NA |
| H2PteGlu | NA | NA | NA | NA |
| H4PteGlu | NA | NA | NA | NA |
| HIAA | NA | NA | NA | NA |
| histidine | 1.4489 | 1.6047 | 0.0016 | 1.2047 |
| histidine-13C6-15N3 | NA | NA | NA | 1.3848 |
| homocitrulline | 1.1695 | 1.3257 | 0.0007 | 0.8646 |
| homocysteic_acid | NA | NA | NA | NA |
| homocysteine | NA | NA | NA | NA |
| Homocysteine sulfinic acid | NA | NA | NA | NA |
| hydroxyproline_gammaALA | 1.4191 | 1.4307 | 0.0845 | 0.9611 |
| hypotaurine | NA | NA | NA | NA |
| hypoxanthine | 1.1270 | 1.1684 | NA | 0.8242 |
| HYPOXANTHINE_13C5 | 0.9932 | 0.8744 | 1.9778 | 0.5983 |
| IMP | NA | NA | NA | NA |
| INDOLE-3-ACETIC ACID | 1.1396 | 1.2232 | NA | 0.7814 |
| INDOLE-3-ACETIC ACID_PHENYL-13C6 | NA | NA | NA | NA |
| indolelactate | 1.7748 | 1.7459 | NA | 1.0991 |
| inosine | 1.1267 | 1.2159 | NA | 0.7927 |
| isocitrate | NA | NA | NA | NA |
| isoleucine | 1.4754 | 1.6429 | 0.0083 | 0.9983 |
| Isoleucine-13C6-15N | NA | NA | NA | 1.5801 |
| Itaconic Acid | 1.1729 | 1.2068 | 1.0939 | 0.7287 |
| Kynurenic Acid | 1.3260 | 1.0142 | NA | 0.8275 |
| kynurenine | 1.4967 | 1.1692 | NA | 0.8055 |
| lactic_acid | 1.7549 | 1.7649 | 0.0013 | 1.1121 |
| L-ALANINE_13C3 | 0.4004 | 0.4074 | 4.0181 | 0.3521 |
| leucine | 1.6417 | 1.7610 | 0.0023 | 1.0042 |
| leucine-13C6-15N | NA | NA | NA | 1.8730 |
| L-LEUCINE_13C6 | 1.2290 | 1.2123 | 2.1680 | 0.4900 |
| L-PHENYLALANINE_RING-13C6 | 1.0491 | 1.0494 | 1.6205 | 0.6323 |
| L-TRYPTOPHAN_13C11 | 1.0685 | 1.1058 | 1.4161 | 0.6872 |
| L-TYROSINE_RING-13C6 | 0.9394 | 1.0162 | 1.7831 | 0.6279 |
| lysine | 1.5513 | 1.5747 | 0.0006 | 1.0077 |
| lysine-13C6-15N2 | NA | NA | 1.0000 | NA |
| Lythocholic acid | NA | NA | NA | NA |
| malate | 1.7265 | 1.7612 | 0.5585 | 1.1810 |
| malonyl-CoA | NA | NA | NA | NA |
| mannose | NA | 1.0000 | NA | NA |
| methionine | 1.5631 | 2.1914 | 0.0006 | 1.2572 |
| methionine-13C5-15N | NA | NA | NA | NA |
| Methionine sulfoxide | 1.8149 | 2.0314 | 0.0023 | 1.2368 |
| methylthioadenosine | NA | NA | NA | NA |
| MTX | NA | NA | NA | NA |
| myo-inositol | NA | NA | NA | NA |
| N-acetylalanine | NA | NA | NA | NA |
| N-acetylaspartate | 1.6002 | 1.7765 | NA | 1.1444 |
| N-acetylcysteine | NA | NA | NA | NA |
| N-acetylglutamate | 1.4045 | 1.4950 | 0.9623 | 0.9787 |
| N-acetylglutamine | NA | NA | NA | NA |
| N-acetylglycine | NA | NA | NA | NA |
| N-acetylmethionine | 0.9510 | 1.0876 | NA | 0.9661 |
| N-acetylornithine | NA | NA | NA | NA |
| N-acetylphenylalanine | 1.2909 | 1.1761 | NA | 0.7371 |
| N-acetylserine | NA | NA | NA | NA |
| NAD+ | NA | NA | NA | NA |
| NADH | NA | NA | NA | NA |
| NADP | NA | NA | NA | NA |
| NADPH | NA | NA | NA | NA |
| N-alpha-acetyllysine | 1.0753 | 1.2832 | NA | 0.7736 |
| niacinamide | 2.0267 | 1.5804 | 0.1482 | 1.1900 |
| NICOTINAMIDE_13C6 | 1.1750 | 1.3616 | 1.0518 | 0.8112 |
| Nicotinic Acid | NA | NA | NA | NA |
| O-phosphoethanolamine | 1.1555 | 1.2703 | NA | 0.7421 |
| ornithine | 1.5476 | 1.7360 | 0.0114 | 1.0631 |
| orotate | 1.1421 | 1.4535 | 0.0259 | 1.1136 |
| palmitate | 1.2129 | 1.2248 | NA | 0.7437 |
| PALMITATE_U-13C16 | NA | NA | NA | NA |
| p-aminobenzoate | 1.1045 | 1.2828 | 0.1711 | 0.8973 |
| Pantothenate | 1.8775 | 1.9560 | 0.0008 | 1.2566 |
| Phenylacetyl glutamine | NA | 1.0000 | NA | NA |
| phenylalanine | 1.8113 | 1.7471 | 0.0010 | 1.0956 |
| phenylalanine-13C9-15N | NA | NA | NA | NA |
| phosphocholine | 2.0162 | 1.8857 | 0.0691 | 1.3127 |
| phosphocreatine | 1.3790 | 1.6088 | 0.3424 | 1.2155 |
| phosphoenolpyruvate | 1.2504 | 1.1764 | NA | 0.7572 |
| phosphoserine | NA | NA | NA | NA |
| Picolinate | NA | NA | NA | NA |
| Pipecolate | 1.1168 | 1.2684 | NA | 0.7627 |
| proline | 1.9584 | 2.0450 | 0.0039 | 1.3200 |
| proline-13C5-15N | NA | NA | NA | NA |
| propionylcarnitine | 1.3653 | 1.5837 | 0.0117 | 0.9247 |
| PRPP | NA | NA | NA | NA |
| pseudouridine_unc | 1.2427 | 1.2899 | NA | 0.8520 |
| PteGlu | NA | NA | NA | NA |
| Pyridoxal | NA | NA | NA | NA |
| Pyridoxine | 1.3289 | 1.0424 | 1.2890 | 0.8283 |
| pyruvate | NA | NA | NA | NA |
| PYRUVATE_13C3 | NA | NA | NA | NA |
| quinolinic_acid | 1.4470 | 1.4656 | 0.0213 | 0.9555 |
| Riboflavin | NA | NA | NA | NA |
| Ribose 1-phosphate_unc | NA | NA | NA | NA |
| Ribose_Ribulose 5-phosphate_3Me-Lys | NA | 1.0000 | NA | NA |
| saccharopine_unc | 1.1147 | 1.2730 | NA | 0.7606 |
| S-Adenosyl-L-Homocysteine | 1.2455 | 1.0993 | NA | 0.8110 |
| S-Adenosyl-L-methionine | 1.5491 | 1.7049 | NA | 1.2517 |
| sarcosine | NA | 1.0000 | NA | NA |
| S-CARBOXYMETHYLCYSTEINE | NA | NA | NA | NA |
| Sedoheptulose-7-phosphate | NA | NA | NA | NA |
| serine | 1.7295 | 1.9143 | 0.1795 | 1.1025 |
| serine-13C3-15N | NA | NA | NA | NA |
| serotonin | NA | NA | NA | NA |
| SODIUM PALMITATE_U-13C16 | NA | NA | NA | NA |
| sorbitol | 1.1111 | 1.4128 | NA | 0.7989 |
| succinate | 1.5121 | 1.5426 | 0.2402 | 0.9282 |
| Succinylacetone | NA | NA | NA | NA |
| succinyl-CoA | NA | NA | NA | NA |
| taurine | 1.6211 | 2.1673 | 0.0008 | 1.2390 |
| thiamine | NA | NA | NA | NA |
| threonine | 1.3746 | 1.3403 | 0.0445 | 0.9043 |
| threonine-13C4-15N | NA | NA | NA | NA |
| thymidine | 1.3736 | 1.3446 | 0.1555 | 0.8650 |
| THYMINE | NA | NA | NA | NA |
| "THYMINE_1,3-15N2" | 1.1973 | 1.1954 | 1.1133 | 0.7144 |
| trans-urocanate | NA | NA | NA | NA |
| tryptamine | NA | NA | NA | NA |
| tryptophan | 1.6127 | 1.5522 | 0.0010 | 0.9920 |
| tyrosine | 1.3647 | 1.3668 | NA | 0.9062 |
| tyrosine-13C9-15N | NA | NA | NA | NA |
| UDP | NA | NA | NA | NA |
| UDP-GlcNAc | NA | NA | NA | NA |
| UMP | 1.7512 | 1.6725 | NA | 0.7849 |
| uracil | 1.1966 | 1.2236 | NA | 0.7527 |
| Ureidosuccinic_acid | 1.3688 | 1.3625 | 1.1524 | 0.8305 |
| uric acid | 1.9204 | 1.5168 | NA | 1.1853 |
| uridine | 1.1124 | 1.2092 | NA | 0.8043 |
| UTP | NA | NA | NA | NA |
| valine | 1.5739 | 1.6775 | NA | 1.0648 |
| valine-13C5-15N | NA | NA | NA | NA |
| xanthine | 1.1214 | 1.8244 | NA | 1.3569 |
| xanthosine | 1.6405 | 2.0159 | 0.3550 | 1.1494 |
Factors:
| F1 | Sample source:embryonic CSF | Developmental Timepoint:E10-12.5 | Treatment (Maternal Injection):PolyIC | Timepoint of Collection:2.5h |
| F2 | Sample source:embryonic CSF | Developmental Timepoint:E10-12.5 | Treatment (Maternal Injection):saline | Timepoint of Collection:2.5h |
| F3 | Sample source:mock tube | Developmental Timepoint:- | Treatment (Maternal Injection):- | Timepoint of Collection:- |
| F4 | Sample source:Pool | Developmental Timepoint:- | Treatment (Maternal Injection):- | Timepoint of Collection:- |
