Data for (Study ST003111)

(Analysis AN005094)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4
4-Acetamidobutanoate 0.1332 0.2827 0.8665 2.1975
5-6-Dihydrouracil 0.6124 0.9342 1.4081 0.8903
5-Hydroxyindoleacetate 0.2678 1.0242 0.5532 1.8620
5-Hydroxyisourate 0.7892 0.8088 1.0333 1.2844
(5-L-Glutamyl)-L-glutamine 1.8828 1.1679 0.4888 0.8137
5-Methylthioadenosine 0.8307 1.1537 0.9592 0.9888
Acetylcarnitine 0.9324 1.3766 0.9478 0.7162
Adenine 1.3406 1.5040 0.8738 0.4179
Adenosine 1.4722 1.2664 0.9006 0.5496
ADP 1.1462 1.0247 1.0497 0.8378
Allantoate 0.3361 0.2408 0.7314 2.4261
alpha-D-Glucosamine 1-phosphate 0.3631 0.5350 1.1885 1.6586
Alpha-linolenyl carnitine 1.3048 1.2545 0.8289 0.7337
AMP 1.4330 1.5228 0.9394 0.2779
Anthranilate 0.5730 0.4012 0.7212 2.1338
Arachidyl carnitine 0.7746 0.4983 1.2073 1.4297
Asymmetric dimethyl arginine 0.2130 0.2039 1.3361 1.9322
Butyrylcarnitine 1.0505 1.1415 0.8523 0.9759
Carnosine 1.3781 1.2014 1.1207 0.4510
CDP-choline 1.1965 1.2034 1.1598 0.5189
Cholesterol 1.0936 0.9364 0.9311 1.0763
Choline 1.4611 1.0921 0.8641 0.7671
Creatine 0.9231 1.0840 0.9124 1.0496
Creatinine 0.1938 0.2916 1.1745 2.0177
Cys-Gly 1.6539 1.6405 0.9035 0.0636
Cytosine 0.7365 0.6458 0.9574 1.5549
D-4--Phosphopantothenate 2.7266 0.9152 0.8363 0.2126
Decanoylcarnitine 1.5421 0.9847 1.0634 0.6266
Diethanolamine 0.4617 0.9991 1.1268 1.1970
Dimethylglycine 0.9033 0.8690 1.0464 1.1426
Docosapentaenoyl carnitine 1.0423 1.0394 0.9924 0.9428
Dodecanedioylcarnitine 0.3716 0.6249 0.7315 2.0207
Dodecanoylcarnitine 1.3849 1.1772 0.9228 0.6690
Dodecenoylcarnitine 1.0565 1.0595 0.9882 0.9183
gamma-Glutamyl-Se-methylselenocysteine 0.2084 0.1800 0.7722 2.5227
gamma-L-Glutamyl-D-alanine 1.5153 1.2051 0.6447 0.8410
gamma-L-Glutamyl-L-cysteine 2.0943 1.5948 0.6450 0.1037
glycine 1.2306 1.1275 0.9670 0.7671
Guanidinoacetate 1.3535 1.4608 1.1739 0.1532
Guanine 1.4513 1.3293 0.9071 0.4928
Guanosine 1.6072 1.3338 0.8548 0.4471
Heptadecanoyl carnitine 1.1500 0.7926 1.0116 1.1058
Hexadecadienoylcarnitine 1.2129 0.9876 1.0392 0.8455
Hexadecenoyl carnitine 1.1669 1.3017 0.9055 0.6927
Hexanoylcarnitine 1.0088 1.0784 1.1604 0.7559
Hydroxydodecanoyl carnitine 1.5567 0.8023 1.1068 0.7568
Hydroxyhexadecanoyl carnitine 1.9270 0.8375 1.1374 0.4689
Hydroxyhexadecenoylcarnitine 1.6829 0.8752 1.1247 0.5904
Hydroxyhexanoyl carnitine 0.3673 0.4523 0.5124 2.4149
Hydroxyisovaleroyl carnitine 0.9394 1.7636 0.8393 0.4335
Hydroxyoctadecenoylcarnitine 1.7199 0.8097 1.1614 0.5970
Hydroxyoctanoyl carnitine 0.9974 0.8192 1.2445 0.9378
Hydroxypentadecanoyl carnitine 0.7796 1.4041 0.9542 0.7740
Hydroxypropionylcarnitine 0.5733 0.8123 0.7382 1.7055
Hydroxytetradecanoyl carnitine 1.8594 0.7764 1.2071 0.5009
Hydroxytetradecenoylcarnitine 1.4007 0.8425 0.9973 0.9197
Hypoxanthine 1.8374 1.2329 0.8822 0.3825
IDP 0.0553 0.0782 0.5371 2.0244
IMP 1.6004 1.5961 0.7877 0.2559
Indole 0.0768 0.1213 0.4190 3.0136
Indole-3-acetate 2.1540 1.3240 0.6518 0.3318
Indoxyl 0.2277 0.2230 0.9317 2.3086
isobutyrylcarnitine 1.0314 1.1996 0.8214 0.9602
Isovalerylcarnitine 0.5755 1.0049 0.7615 1.4883
Kynurenic acid 0.0544 0.1905 0.6993 2.6775
Kynurenine 0.5545 0.4455 0.8714 1.9504
L-Adrenaline 0.9412 1.1284 1.2274 0.6794
L-alanine 1.1670 1.0757 1.0444 0.7798
L-arginine 0.3402 0.3223 0.8555 2.2180
L-asparagine 0.6476 0.6150 0.9277 1.6688
L-aspartate 1.3039 1.3163 1.0312 0.4702
L-Carnitine 1.0843 1.4731 1.0327 0.4437
L-Citrulline 0.2781 0.2545 0.6352 2.5435
L-cysteine 1.8926 1.0730 0.8281 0.5633
L-cystine 1.6137 0.4902 0.1177 2.0239
L-glutamate 1.2679 1.2215 1.1184 0.4994
L-glutamine 1.0849 1.0600 1.0553 0.8337
L-histidine 0.5821 0.5752 0.9554 1.7202
L-Homocysteine 1.8374 1.2329 0.8822 0.3825
Linoleyl carnitine 1.1009 1.1660 0.9036 0.8699
L-isoleucine 0.4054 0.3045 0.8398 2.2124
L-leucine 0.7732 0.6017 1.0576 1.4768
L-lysine 0.2369 0.2364 0.8936 2.3278
L-methionine 0.3025 0.2287 0.7578 2.4320
L-Methionine S-oxide 0.1570 0.1413 1.1059 2.2586
L-phenylalanine 0.2936 0.2224 0.8020 2.3994
L-proline 0.7787 0.7292 0.8835 1.5200
L-serine 0.7103 0.6287 1.0614 1.4837
L-threonine 0.6959 0.5518 1.1096 1.5211
L-tryptophan 0.4421 0.3472 0.8312 2.1564
L-tyrosine 0.3261 0.2774 0.8488 2.2782
L-valine 1.1970 1.1103 1.2289 0.5426
Malonylcarnitine 1.1852 1.3929 0.7177 0.7783
Methylglutarylcarnitine 1.4439 1.5885 0.7195 0.4257
Methylmalonylcarnitine 0.7862 1.2044 0.8719 1.0520
Mevalonate 0.3794 0.7943 0.7711 1.8069
N1-Acetylspermidine 0.4710 0.5193 1.1384 1.6597
N4-(Acetyl-beta-D-glucosaminyl)asparagine 0.1131 0.1775 0.4519 2.9027
N6-Methyl-L-lysine 0.8096 0.4378 0.5064 2.1700
N6-N6-N6-Trimethyl-L-lysine 0.3303 0.4259 1.0377 1.9382
N-acetyl-D-glucosamine 0.4505 0.3523 1.2508 1.7266
N-Acetyl-L-aspartate 0.3148 0.3000 1.2316 1.8796
N-Acetyl-leucyl-leucine 0.0309 0.0450 0.4703 3.0661
N-Acyl-D-glutamate 0.1425 0.3102 1.4120 1.7923
N-Amidino-L-aspartate 0.1388 0.3584 0.5933 2.5650
N-Carbamoyl-L-aspartate 0.1893 0.3458 1.2210 1.9195
N-Carbamyl-L-glutamate 0.1265 0.2652 0.7745 2.4843
Nicotinamide 1.5358 1.6510 0.6730 0.3545
Nicotinic acid 0.4516 0.4187 0.9353 1.9750
Nonanoylcarnitine 1.4125 1.1227 0.6493 0.9805
Octadecenylcarnitine 1.2263 1.1360 0.9901 0.7381
Octanoylcarnitine 1.2648 1.1213 1.0727 0.6471
Octenoylcarnitine 0.8330 1.1754 0.9161 1.0087
Ornithine 0.3226 0.2834 0.8433 2.2797
Palmitoylcarnitine 1.1879 1.1203 1.0009 0.7661
Pantetheine 0.0342 0.0448 0.5810 2.9537
Pantetheine 4--phosphate 1.5447 0.5464 0.5312 1.5956
Pantothenol 0.4965 0.4806 0.7848 2.0367
Pentadecanoylcarnitine 1.0164 1.0624 0.8185 1.1092
Pimelylcarnitine 0.4883 0.8122 0.9580 1.5368
Propanoyl-carnitine 1.1277 1.7117 0.9089 0.3028
Propenoylcarnitine 0.3230 0.4131 1.3617 1.6314
Putrescine 0.6142 0.9958 1.0177 1.2180
Pyridoxal 0.2236 0.5131 0.9403 2.0125
Pyridoxamine 5^-phosphate 1.4691 1.5530 0.9710 0.1945
Riboflavin 0.3535 0.2987 0.5478 2.5415
S-Adenosyl-L-homocysteine 1.6431 1.5074 0.9387 0.1681
S-Adenosyl-L-methionine 0.8807 0.9824 1.1152 0.9740
Spermidine 0.3017 0.3151 1.1332 1.9707
Spermine 0.2717 0.1938 1.4400 1.8032
Sphingosine 1.1174 0.7239 1.3785 0.8271
Stearoylcarnitine 1.0554 0.7833 1.1475 1.0360
Tetradecanoylcarnitine 1.2827 1.2637 0.8961 0.6706
Tetradecenoylcarnitine 1.1771 1.1773 0.9014 0.8150
Thymidine 0.2591 0.3819 0.5842 2.4784
Thymine 0.4048 0.4981 1.0891 1.7700
Tiglylcarnitine 0.2795 0.4046 0.8588 2.1689
trans-4-Hydroxy-L-proline 1.0585 0.9981 1.0578 0.9090
Triethanolamine 0.6143 0.9036 1.1606 1.1673
Uracil 0.6599 0.4421 1.1526 1.6094
Xanthine 1.7368 1.0603 1.0014 0.4962
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Factors:

F1Factor:Ctrl-Asns-ASO
F2Factor:Ctrl-Scr-ASO
F3Factor:KO-Asns-ASO
F4Factor:KO-Scr-ASO
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