Data for (Study ST003111)
(Analysis AN005095)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 10-Formyldihydrofolate | 1.3194 | 1.7001 | 0.8590 | 0.2492 |
| 10-Hydroxydecanoic acid | 0.9942 | 1.0634 | 0.9487 | 0.9914 |
| 2-3-Bisphosphoglycerate | 1.1177 | 0.9642 | 0.9959 | 0.9692 |
| 2/3-Phospho-D-glycerate | 1.0925 | 1.3947 | 0.7892 | 0.7606 |
| 2-Hydroxyglutarate | 0.5821 | 0.9372 | 1.0554 | 1.2581 |
| 2-Oxoglutaramate | 0.4576 | 0.5951 | 1.0309 | 1.6995 |
| 2-Oxoglutarate | 0.3395 | 0.2773 | 1.0632 | 2.0558 |
| 3-Hydroxyisobutyrate | 0.9299 | 0.6367 | 0.6934 | 1.7120 |
| 4-Pyridoxate | 0.0505 | 0.0661 | 0.6752 | 2.8284 |
| 5-6-Dihydrothymine | 0.8165 | 0.8340 | 1.0235 | 1.2527 |
| 5-Oxoproline | 1.4816 | 1.0444 | 0.8355 | 0.8312 |
| 5-Phospho-alpha-D-ribose 1-diphosphate | 1.7245 | 1.7596 | 0.6294 | 0.1763 |
| (5Z-8Z-11Z-14Z-17Z)-Icosapentaenoic acid | 1.7517 | 1.5892 | 0.6288 | 0.3310 |
| 6-Phospho-D-gluconate | 0.0629 | 0.0916 | 0.4110 | 3.0597 |
| (7Z-10Z-13Z-16Z-19Z)-Docosa-7-10-13-16-19-pentaenoic acid | 1.4704 | 1.5833 | 0.6432 | 0.4912 |
| (8Z-11Z-14Z)-Icosatrienoic acid | 1.8817 | 1.4433 | 0.7577 | 0.2699 |
| 9-Oxononanoic acid | 0.9515 | 1.0351 | 0.9550 | 1.0390 |
| Acetyl-CoA | 1.1214 | 0.6456 | 1.0904 | 1.1912 |
| Adenylosuccinic acid | 1.8221 | 0.9613 | 1.0599 | 0.4856 |
| ADP-D-ribose | 1.1375 | 1.2434 | 0.5943 | 1.0799 |
| alpha-D-Ribose 1-phosphate | 0.9531 | 1.0069 | 0.9091 | 1.1121 |
| Argininosuccinate | 0.5369 | 0.3780 | 0.5053 | 2.3945 |
| Ascorbate | 1.1609 | 1.3796 | 1.1470 | 0.3768 |
| ATP | 0.8231 | 1.3350 | 0.9332 | 0.8380 |
| Butanoic acid | 0.8309 | 0.7636 | 0.8470 | 1.4909 |
| Carbamoyl phosphate | 0.2244 | 0.1975 | 0.7563 | 2.5116 |
| CDP | 1.5562 | 1.2576 | 0.7077 | 0.7009 |
| cis-Aconitate | 0.2027 | 0.1866 | 0.9714 | 2.3204 |
| Citrate | 0.4362 | 0.2418 | 0.8350 | 2.2615 |
| CMP | 0.2033 | 0.2739 | 0.6949 | 2.5092 |
| CMP-N-acetylneuraminate | 1.3163 | 1.3057 | 0.9858 | 0.5187 |
| CTP | 1.5536 | 0.8218 | 1.2060 | 0.6401 |
| Cystathionine | 0.6071 | 1.3047 | 0.7049 | 1.2261 |
| Cytidine | 1.2737 | 1.4346 | 0.9696 | 0.4315 |
| D-Arabitol/Xylitol/Ribitol | 0.1311 | 0.1754 | 0.7598 | 2.5862 |
| Decanoic acid (caprate) | 1.0905 | 0.9598 | 1.0483 | 0.9376 |
| Dehydroascorbate | 1.1575 | 1.0913 | 1.1036 | 0.7106 |
| D-Fructose 1-6-bisphosphate | 0.8697 | 1.2480 | 0.7869 | 1.0433 |
| D-Glucose | 0.8052 | 0.8130 | 1.0002 | 1.3037 |
| D-Glyceraldehyde 3-phosphate/Glycerone phosphate | 1.0952 | 0.9524 | 0.9191 | 1.0713 |
| D-Hexose-phosphate | 1.1056 | 1.3040 | 0.9604 | 0.6723 |
| Diphosphate | 1.3510 | 1.6235 | 0.9305 | 0.2354 |
| Docosahexaenoic acid | 1.6329 | 1.4911 | 0.6899 | 0.4393 |
| Dodecanedioic acid | 0.9022 | 1.0393 | 0.8671 | 1.1523 |
| Dodecanoic acid | 1.2345 | 0.9521 | 0.9768 | 0.9304 |
| D-Rhamnose | 0.2336 | 0.3015 | 1.0151 | 2.1433 |
| D-Ribitol 5-phosphate | 1.1044 | 1.0779 | 0.7908 | 1.0687 |
| D-Ribose | 0.1592 | 0.2361 | 0.7347 | 2.5337 |
| D-Ribose 5-diphosphate | 0.9120 | 1.1717 | 1.0228 | 0.8584 |
| Eicosapentaenoic acid | 1.7517 | 1.5892 | 0.6288 | 0.3310 |
| Eicosatetraenoic acid | 1.5714 | 1.2549 | 0.7614 | 0.6409 |
| FAD | 1.5913 | 1.4000 | 0.8904 | 0.3548 |
| FADH2 | 2.5729 | 1.3824 | 0.5850 | 0.0888 |
| Flavin mononucleotide | 1.3686 | 1.2143 | 1.0786 | 0.4859 |
| Folate | 0.8172 | 1.1746 | 0.9669 | 0.9682 |
| Fumarate | 1.2191 | 1.3355 | 1.1431 | 0.3899 |
| GDP | 1.5140 | 1.3516 | 0.7675 | 0.5725 |
| Glutathione | 1.6425 | 1.5347 | 1.0105 | 0.0692 |
| Glutathione disulfide | 1.2641 | 1.4140 | 1.0153 | 0.4123 |
| Glycerol 3-phosphate | 1.2991 | 1.0497 | 0.9830 | 0.7879 |
| Glycolate | 0.8982 | 0.8825 | 0.9469 | 1.2316 |
| GMP | 1.3741 | 1.3057 | 1.0207 | 0.4491 |
| GTP | 0.5879 | 1.6157 | 0.9400 | 0.6916 |
| Heptanoic acid | 1.1377 | 1.0526 | 1.0399 | 0.8249 |
| Hexadecanoic acid | 1.1028 | 1.0083 | 0.9960 | 0.9340 |
| Hexadecenoic acid | 0.9729 | 1.7101 | 0.5995 | 0.7067 |
| Hexanoic acid (caproate) | 1.1623 | 1.0384 | 0.9479 | 0.9163 |
| Hypotaurine | 1.2212 | 1.1068 | 1.3208 | 0.4397 |
| Inosine | 1.7746 | 1.2962 | 0.8637 | 0.3754 |
| Itaconate | 0.4217 | 0.3665 | 0.9158 | 2.0647 |
| Lactate | 0.6997 | 0.6941 | 0.9859 | 1.5002 |
| Malate | 1.3048 | 0.8460 | 1.1802 | 0.7910 |
| Mannitol/Sorbitol | 0.4142 | 2.0120 | 0.6473 | 0.6922 |
| N5-Methyl-L-glutamine | 0.8094 | 0.6553 | 0.7856 | 1.6734 |
| N-Acetyl-L-citrulline | 0.1387 | 0.1985 | 0.9032 | 2.4151 |
| N-Acetyl-L-ornithine | 0.6272 | 0.7987 | 0.6935 | 1.7315 |
| N-Acetylmethionine | 0.5520 | 0.9061 | 0.7504 | 1.6123 |
| N-Acetylneuraminate | 0.5662 | 0.4755 | 0.9331 | 1.8517 |
| NAD+ | 1.3510 | 1.4355 | 1.0099 | 0.3439 |
| NADH | 1.3203 | 1.4514 | 1.0061 | 0.3503 |
| NADP+ | 1.7005 | 1.5924 | 0.7113 | 0.2759 |
| NADPH | 1.8092 | 1.6011 | 0.6998 | 0.2135 |
| N-Glycoloyl-neuraminate | 0.5609 | 0.4352 | 0.6576 | 2.1707 |
| Nonanoic acid (pelargonate) | 1.0988 | 0.9719 | 1.0491 | 0.9197 |
| Octadecadienoic acid | 1.2927 | 1.2123 | 0.8787 | 0.7334 |
| Octadecanoic acid | 0.9833 | 0.9260 | 0.9984 | 1.0856 |
| Octadecatrienoic acid | 1.3936 | 1.3407 | 0.8097 | 0.6135 |
| Octadecenoic acid | 1.1618 | 1.3088 | 0.8377 | 0.7564 |
| Octanoic acid (caprylate) | 1.1403 | 1.0891 | 0.9958 | 0.8309 |
| Orotate | 0.2932 | 0.2780 | 1.3801 | 1.7660 |
| Orotidine 5--phosphate | 0.1741 | 0.2236 | 0.8000 | 2.4718 |
| Oxaloacetate | 0.4027 | 0.1895 | 0.8951 | 2.2738 |
| Oxalosuccinate | 0.8357 | 1.0326 | 0.9476 | 1.1184 |
| Phosphate | 1.2588 | 1.3260 | 1.0162 | 0.5025 |
| Phosphocreatine | 0.8042 | 0.8154 | 0.8780 | 1.4242 |
| Phosphoenolpyruvate | 1.0456 | 1.2921 | 0.6669 | 1.0136 |
| Phosphoethanolamine | 0.9002 | 1.0476 | 1.1811 | 0.8311 |
| Prostaglandin E2 | 0.6358 | 0.3555 | 0.7112 | 2.1518 |
| Pyruvate | 0.9998 | 0.9677 | 1.0244 | 1.0081 |
| S-Acylglutathione | 0.9092 | 0.9141 | 1.0176 | 1.1228 |
| (S)(+)-Allantoin | 0.1584 | 0.2101 | 0.9371 | 2.3577 |
| (S)-Dihydroorotate | 0.1785 | 0.1463 | 0.5649 | 2.7818 |
| Sedoheptulose 1-phosphate | 1.2499 | 0.9645 | 0.8763 | 1.0092 |
| S-Glutathionyl-L-cysteine | 1.2606 | 0.6805 | 0.4062 | 1.7569 |
| sn-glycero-3-Phosphocholine | 0.8233 | 0.8415 | 1.0676 | 1.1969 |
| sn-glycero-3-Phosphoethanolamine | 1.1927 | 1.5382 | 0.9423 | 0.4038 |
| Sphingosine 1-phosphate | 1.0851 | 1.2613 | 1.0229 | 0.6648 |
| Succinate | 1.4707 | 1.2060 | 1.0158 | 0.4957 |
| Taurine | 1.0975 | 1.2545 | 1.0137 | 0.6732 |
| Taurochenodeoxycholate | 0.1641 | 0.6124 | 1.4436 | 1.4456 |
| Taurocholate | 0.2231 | 0.7759 | 1.4170 | 1.2732 |
| Tetradecanoic acid | 1.1171 | 1.1877 | 0.8513 | 0.8908 |
| Tetradecenoic acid | 0.8539 | 1.7174 | 0.6924 | 0.6779 |
| UDP | 1.4662 | 1.2488 | 0.8645 | 0.6070 |
| UDP-D-glucuronate | 2.1920 | 1.1625 | 0.6439 | 0.4784 |
| UDP-glucose | 1.3923 | 1.3259 | 0.9032 | 0.5355 |
| UDP-N-acetyl-D-glucosamine | 1.2692 | 1.3025 | 0.8622 | 0.6737 |
| UMP | 1.5940 | 1.4961 | 0.7552 | 0.3924 |
| Urate | 0.6785 | 0.5362 | 1.1128 | 1.5439 |
| UTP | 0.7450 | 1.6154 | 0.9862 | 0.5515 |
Factors:
| F1 | Factor:Ctrl-Asns-ASO |
| F2 | Factor:Ctrl-Scr-ASO |
| F3 | Factor:KO-Asns-ASO |
| F4 | Factor:KO-Scr-ASO |
