Data for (Study ST003177)

(Analysis AN005215)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8
1-Methyladenosine 1.9634 1.9610 1.8838 1.6543 0.4087 0.4029 1.9679 0.8980
1-Methylguanosine 0.7108 0.8330 1.0242 1.0099 1.0671 1.0798 0.8439 0.9061
1-Methylnicotinamide 0.3917 1.1451 1.3040 0.5420 1.0640 0.7967 1.4453 0.1098
3-Acetamidopropanal 1.1838 0.8472 0.8365 0.9092 1.1582 0.9624 0.9054 0.6797
3-Aminoisobutyric acid 1.7065 0.8164 0.6965 0.7778 1.1979 1.0045 0.7331 0.7879
3-Hydroxyanthranilate NA 0.1696 1.5966 0.8753 1.2499 0.8948 2.8821 NA
3-Hydroxy-L-kynurenine 3.8621 0.6544 0.9172 1.1514 1.1853 0.7656 2.0660 0.6080
4-Acetamidobutanoate 0.9062 0.6515 0.6830 0.9936 1.1921 1.1471 0.7838 0.8411
4-Trimethylammoniobutanoate 0.4568 1.1841 0.9043 0.9556 1.0974 0.7883 0.4729 0.5969
5-Aminolevulinate 1.5670 1.5608 1.4399 1.6256 0.5575 0.6777 2.1858 0.9462
5-Aminopentanoic acid 0.7086 0.7946 0.8366 0.9470 1.1451 1.0851 0.6445 0.8505
5-Hydroxyindoleacetate NA 0.5721 2.2442 0.2727 1.3826 0.7713 1.2098 NA
5-Hydroxy-L-tryptophan NA 0.8165 1.0267 0.8321 1.2008 0.9220 0.9630 NA
5-Oxoproline 0.6292 0.7793 0.8325 0.8604 1.1615 1.1136 0.6914 0.3927
6-Methyladenosine 0.3700 1.5588 1.8481 2.4028 0.5480 0.5702 0.6786 0.8351
8-Hydroxy-deoxyguanosine NA 0.6711 0.8954 0.7821 1.2786 1.0056 1.0919 NA
8-hydroxyguanosine NA NA NA NA 1.6337 0.3663 NA NA
Acetylcholine 0.9891 0.9998 0.7641 1.0115 0.9863 1.0850 0.9351 NA
Adenosine 1.3733 0.6678 0.5210 0.8862 1.2247 1.0502 1.5424 0.6183
alpha-Tocopherol 1.8479 1.7520 1.7068 0.4115 0.6890 0.6844 1.5301 0.3826
Anthranilate 0.2952 1.1712 1.9397 0.6231 0.9958 0.7416 0.8562 NA
Betaine 0.3264 0.7389 0.8224 0.8045 0.9875 1.4080 1.4922 0.1416
Bilirubin 2.4003 2.9471 2.4205 0.3024 0.1163 0.1149 2.5780 0.0516
Cadaverine 0.3292 0.3523 0.4750 0.8492 1.3782 1.3245 0.3157 0.9351
Carnitine 0.7314 0.7312 0.7387 1.0096 1.1471 1.1329 0.7453 1.0628
Carnosine 0.6560 0.8312 0.8630 0.9728 1.0983 1.1288 0.5330 0.9843
Choline 0.8349 0.9251 1.1383 0.8705 1.0646 1.0206 0.6679 0.9742
Creatine 0.3408 0.9081 0.9441 0.8258 0.8545 1.5835 0.3353 0.6085
Creatinine 0.8550 0.8173 0.7727 1.0892 1.1037 1.0779 0.7611 0.9867
Cys-Gly 1.2078 1.2078 1.0827 0.5711 0.6681 0.5810 0.8870 NA
Cysteamine 0.7021 1.1590 0.9396 1.1284 0.9297 0.9157 0.7953 3.2995
Cytidine 0.8438 1.5532 2.1975 1.1773 0.6522 0.7119 0.6141 0.7559
Cytosine 0.5822 0.4540 0.6542 1.3173 1.2203 1.2169 0.5055 1.0796
Deoxyuridine NA 0.7477 1.2177 0.4321 1.2470 1.0127 0.7915 NA
D-Glucosamine 0.5165 0.4476 0.5169 1.2472 1.1792 1.3513 0.7361 1.1201
Dimethylglycine 0.7793 0.8484 0.9696 0.9578 1.0700 1.0822 0.8639 1.0720
D-Mannose 2.3367 0.7470 0.9842 1.4440 0.8259 1.2103 1.6009 NA
D-Sorbitol NA 0.9951 0.2535 0.4842 1.5159 0.7434 1.1378 NA
Ethyl 4-aminobutyrate 0.4322 0.6019 0.5497 0.7881 1.3654 1.0427 0.6501 NA
Glycerol NA 1.0000 NA NA NA NA NA NA
Guanosine NA 0.6147 NA 1.7077 0.8156 1.4491 0.3969 1.2969
Guanosine 5^-monophosphate 0.2615 0.2664 0.1486 0.2628 1.3289 1.1195 0.3215 0.2573
Hydroxyproline 0.3408 0.6240 0.3783 1.2529 1.2466 1.1700 0.4191 0.3489
Indole 0.2444 0.3187 0.2240 0.9481 1.3963 1.3524 0.2793 NA
Indole-3-acetate 0.4383 0.6646 0.6027 0.6432 1.2325 1.2722 0.5203 0.7782
Indolelactate 0.6419 0.7203 0.5699 0.9356 1.1744 1.1856 0.6306 1.2881
IndolePyruvate 0.8796 1.1241 2.2296 0.9369 0.7632 0.7152 0.3507 9.6262
Inosine 0.0534 1.1264 4.4089 0.0957 0.8751 0.6016 0.0691 0.2910
L-Adrenaline 0.4325 0.4358 0.4056 0.7276 1.1437 1.6799 0.6644 0.8916
L-Alanine 0.7063 0.7369 0.7743 0.9203 1.1711 1.1084 0.7069 1.1435
L-Arginine 0.4433 0.4533 0.4770 0.8990 1.3237 1.2655 0.4520 1.2961
L-Asparagine 1.7440 2.3597 2.8035 1.9839 0.1208 0.1331 1.9338 1.1488
L-Aspartate 0.6093 0.6708 0.6641 1.0627 1.1039 1.0098 1.3389 2.7157
L-Cysteine 1.4692 1.4339 2.0800 0.8885 0.4776 0.5296 1.3868 0.8214
L-Cystine 1.5231 1.8265 2.6339 0.3810 0.5674 0.5496 1.7421 0.4133
L-Glutamate 0.2801 0.3457 0.4322 0.8975 1.3986 1.3025 0.2373 0.9581
L-Glutamine 1.7944 1.7136 1.8014 1.3504 0.3633 0.9119 1.8165 0.7664
L-Glycine 0.6905 0.8427 0.9460 0.9663 1.1158 1.0409 0.6878 0.9548
L-Histidine 0.5855 0.6126 0.6004 0.7494 1.2661 1.2097 0.5793 0.8269
L-Homocysteine 0.9128 0.9317 0.9540 0.6667 1.1253 1.0324 0.6209 0.9806
L-Homoserine 0.7388 0.8210 0.7972 1.0300 1.1181 1.0639 0.7445 1.1910
L-Isoleucine 0.6814 0.7535 0.7422 1.2185 1.1130 1.0957 0.7410 1.2114
L-Kynurenine 0.7846 0.7829 0.7620 0.9835 1.1146 1.0807 1.1914 0.8481
L-Leucine 0.7125 0.8171 0.7926 1.0913 1.0959 1.0896 0.7405 1.2171
L-Lysine 0.7834 0.7682 0.7215 1.0267 1.1593 1.0636 0.7544 1.1755
L-Methionine 0.7103 0.8495 0.8390 0.4358 1.1686 1.1352 0.7769 1.2778
L-Normetanephrine 0.4842 0.6399 0.5400 1.1006 1.2211 1.0907 0.7074 1.0550
L-Ornithine 1.0099 0.8881 0.8513 0.9748 1.0728 1.0569 0.9056 0.7303
L-Phenylalanine 0.6837 0.7623 0.9500 0.9105 1.1310 1.1119 0.6879 1.0943
L-Pipecolate 0.3900 0.7439 0.6677 1.0469 1.1272 1.1855 0.8266 0.5367
L-Proline 3.2422 1.0550 0.6899 0.8920 1.1353 0.6899 1.2784 0.2197
L-Serine 0.7160 0.8394 0.9293 0.9662 1.1061 1.0659 0.6408 1.1931
L-Threonine 0.7395 0.8206 0.7929 1.0232 1.1189 1.0689 0.7362 1.1498
L-Tryptophan 0.7215 0.8480 0.8254 1.1217 1.0883 1.0504 0.7485 1.1680
L-Tyrosine 0.6886 0.8236 0.8840 1.0181 1.1007 1.0656 0.7688 1.3675
L-Valine 0.4688 0.9611 0.5509 1.2797 1.0973 1.0164 0.4245 0.6412
Melatonin 0.6637 0.6548 0.8246 0.9161 1.1865 1.1489 0.6570 1.0010
Methylthioadenosine NA 0.5713 1.6328 1.2155 0.7649 0.9884 3.6950 NA
N1-Acetylspermine 2.6130 0.8729 0.8392 0.8273 1.1107 0.9139 0.9761 2.0158
N8-Acetylspermidine 0.8792 0.8479 0.9088 0.9201 1.0797 1.1295 0.6797 0.6545
N-Acetylputrescine 0.6836 0.7056 1.0829 0.5966 1.1173 1.2608 0.7976 0.8205
Nicotinamide 1.5628 1.0827 1.5567 0.8758 0.9479 0.7436 1.8621 0.6762
Nicotinamide mononucleotide 0.4792 0.5942 NA 0.7317 1.2591 0.9665 0.7054 NA
N-Methylhistamine NA 0.6449 0.7322 0.7609 1.1859 0.9036 2.5377 NA
N(pi)-Methyl-L-histidine 0.5797 0.7409 0.4835 1.7636 0.9785 1.2607 0.5853 1.4435
O-Acetylcarnitine 0.3600 1.6933 0.6708 1.9644 0.5424 1.0201 0.3548 0.3081
O-Phosphotyrosine NA 0.7387 0.9294 0.5275 1.3239 1.0266 0.8495 NA
Putrescine NA 1.2403 3.6404 1.5930 0.5764 0.5450 1.5570 NA
Pyridoxine NA 0.4348 0.4983 0.5963 1.9098 0.6017 0.8500 NA
S-Adenosylmethionine 1.9059 0.6528 0.4503 2.2650 0.3354 0.6832 1.7921 0.9606
Salicyluric acid NA 0.6816 1.5287 0.4539 1.1069 1.0168 1.8126 NA
Sarcosine 0.8090 1.1610 0.5647 1.0585 0.9408 1.0599 1.1024 0.5193
Serotonin 2.2484 1.1404 1.7068 1.1514 0.7437 0.6514 3.4567 0.7236
Spermidine 1.2854 0.6155 0.6958 1.1834 1.1281 1.1168 1.2178 0.7113
Spermine 0.7693 0.6610 0.6669 0.9331 1.1487 1.0488 1.0297 NA
Taurine 0.9470 1.2081 1.6923 0.7840 0.9365 0.7740 1.0026 0.9218
Trimethylamine 0.3530 0.7747 0.5753 0.4452 1.2363 1.2753 0.3045 0.4037
Trimethylamine-N-oxide 0.7437 0.9163 1.2186 1.0846 1.0456 0.9606 0.7395 0.9095
Tryptamine 0.8923 0.8887 0.6691 1.5494 1.0560 0.9278 0.9972 0.8784
Tyramine 1.0205 0.9852 0.8337 1.1507 1.0961 0.7081 0.9176 2.1373
Uridine 1.0141 1.0542 1.0605 0.7918 1.0367 0.9583 0.8453 0.8293
Xanthurenate 0.6986 0.7671 0.6025 0.9949 1.1023 1.2046 0.7788 1.6550
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Factors:

F1Clinical group:CCP-RA | Sample source:blood
F2Clinical group:health | Sample source:blood
F3Clinical group:OA | Sample source:blood
F4Clinical group:pre-RA | Sample source:blood
F5Clinical group:RA-follow | Sample source:blood
F6Clinical group:RA | Sample source:blood
F7Clinical group:RF-RA | Sample source:blood
F8Clinical group:- | Sample source:blood
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