Data for (Study ST003199)

(Analysis AN005249)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
10-Hydroxydecanoate 1.3129 0.6871
1-Methyladenosine 1.0755 0.9245
1-Methyl-L-Histidine/3-Methyl-L-Histidine 0.9587 1.0413
2-Aminoisobutyrate/Aminobutyrate 1.0370 0.9630
2-hydroxybutyrate/2-hydroxyisobutyrate 0.8508 1.1492
2-hydroxyglutarate 0.9950 1.0050
2-Keto-3-Deoxy-D-Gluconic Acid/Gluconolactone 0.9048 1.0952
2-ketobutyrate/Acetoacetate 1.1948 0.8052
2-Methylmaleate 1.1099 0.8901
2-phosphoglycerate 1.0943 0.9057
2-Propenoate 1.0053 0.9947
3-(4-Hydroxyphenyl)Pyruvate_02 1.0457 0.9543
3-hydroxybutyrate 0.8470 1.1530
3-Hydroxymethylglutarate 1.0283 0.9717
3-Methyl-2-Oxovalerate/Ketoleucine 0.6904 1.3096
3-phosphoglycerate 1.0984 0.9016
4-Hydroxyphenyllactate 0.8370 1.1630
4-Imidazoleacetate 0.9754 1.0246
4-Pyridoxate 0.9631 1.0369
Acetylcarnitine 1.0198 0.9802
Acetyl-CoA 1.3180 0.6820
Acetylserine 0.7866 1.2134
Aconitate 0.9549 1.0451
Adenine 0.9566 1.0434
Adenosine 0.9179 1.0821
Adenosine 2^,3^-Cyclic Phosphate 0.9855 1.0145
Adenosine 5^-Diphosphate 1.0500 0.9500
Adenosine Diphosphate Ribose 0.9935 1.0065
Adenosine monophosphate/Deoxyguanosine monophosphate 0.9549 1.0451
Adenosine Triphosphate 1.0589 0.9411
Adenylsuccinate 1.4001 0.5999
AICAR 1.2698 0.7302
Alanine 0.9742 1.0258
Allantoin 1.0029 0.9971
Allothreonine/Threonine 0.8547 1.1453
alpha-Ketoglutarate 1.0287 0.9713
Aminoadipate_01 0.9872 1.0128
Anserine 1.2254 0.7746
Arginine 0.9861 1.0139
Argininosuccinate 1.1968 0.8032
Asparagine 0.9674 1.0326
Aspartate 1.0945 0.9055
Azelate 1.3683 0.6317
Benzoate/Hydroxybenzaldehyde 0.9457 1.0543
Beta-Alanine 0.9441 1.0559
Betaine 0.9279 1.0721
C10:0 Carnitine 1.0534 0.9466
C10:1 Carnitine 1.3238 0.6762
C12:0-Carnitine 1.1164 0.8836
C12:0-OH Carnitine 1.2453 0.7547
C12:1 Carnitine 1.3395 0.6605
C12:1-OH Carnitine 1.2342 0.7658
C14:0-Carnitine 1.2060 0.7940
C14:0-OH Carnitine 1.2659 0.7341
C14:1 Carnitine 1.2341 0.7659
C14:1-OH Carnitine 1.2988 0.7012
C14:2 Carnitine 1.3424 0.6576
C14:2-OH Carnitine 1.4046 0.5954
C15:0 Carnitine 1.1560 0.8440
C16:0 Carnitine 1.0134 0.9866
C16:0-OH Carnitine 1.2947 0.7053
C16:1 Carnitine 1.2033 0.7967
C16:1-OH Carnitine 1.3503 0.6497
C16:2 Carnitine 1.2033 0.7967
C16:2-OH Carnitine 1.2221 0.7779
C17:0 Carnitine 1.0351 0.9649
C18:0-Carnitine 0.9704 1.0296
C18:0-OH Carnitine 1.1312 0.8688
C18:1 Carnitine 1.0528 0.9472
C18:1-OH Carnitine 1.2525 0.7475
C18:2 Carnitine 1.0974 0.9026
C18:2-OH Carnitine 1.3405 0.6595
C18:3 Carnitine 1.2124 0.7876
C18:3-OH Carnitine 1.3578 0.6422
C20:0 Carnitine 0.9137 1.0863
C20:1 Carnitine 0.9482 1.0518
C20:2 Carnitine 0.9532 1.0468
C20:4 Carnitine 0.9105 1.0895
C3:0 Carnitine 0.9489 1.0511
C4:0 Carnitine 0.9050 1.0950
C4:0-DC Carnitine 0.7914 1.2086
C4:0-OH Carnitine 0.9045 1.0955
C5:0 Carnitine 0.8406 1.1594
C5:0-DC Carnitine_01 0.8232 1.1768
C5:0-DC Carnitine_02 1.0460 0.9540
C5:0-OH Carnitine 0.9942 1.0058
C6:0 Carnitine 0.9678 1.0322
C6:0-DC Carnitine 1.0105 0.9895
C6:0-OH Carnitine_01 1.0753 0.9247
C6:0-OH Carnitine_02 1.1580 0.8420
C8:0-Carnitine 0.8996 1.1004
C8:OH-Carnitine 1.0421 0.9579
Caprylate 1.0438 0.9562
Carnitine 0.8943 1.1057
CDP-choline 0.9618 1.0382
CDP-Ethanolamine 1.0166 0.9834
Cellobiose/Maltose/Lactose/Trehalose 0.7145 1.2855
Choline 0.8871 1.1129
Citramalate 0.9321 1.0679
Citrate 0.9325 1.0675
Citrulline 0.9063 1.0937
Coenzyme A 1.0417 0.9583
Creatine 0.9940 1.0060
Creatinine 0.8369 1.1631
Cystathionine 0.7110 1.2890
Cysteinylglycine 0.9764 1.0236
Cytidine 0.8672 1.1328
Cytidine monophosphate(CMP) 0.8834 1.1166
Cytosine 0.8719 1.1281
Deoxycarnitine 1.0877 0.9123
Deoxycytidine 0.9214 1.0786
Deoxyguanosine monophosphate/Adenosine monophosphate 0.9636 1.0364
Deoxyuridine 0.8721 1.1279
Dihydrobiopterin 0.9487 1.0513
Dihydrorotate 1.1975 0.8025
Dihydrouracil 1.0346 0.9654
D-Sedoheptulose 7-phosphate 1.0268 0.9732
FAD 1.0322 0.9678
Fucose/Rhamnose 0.9713 1.0287
Fumarate 1.1185 0.8815
Galactarate/Saccharate 0.8593 1.1407
Gamma-Aminobutyrate 0.9654 1.0346
gamma-Glutamylcysteine 1.0007 0.9993
Gluconate 0.9828 1.0172
Glucosamine/Mannosamine/Hexosamine_01 0.8541 1.1459
Glucosamine/Mannosamine/Hexosamine_02 0.9495 1.0505
Glucose 0.9810 1.0190
Glucose 1-Phosphate/Galactose 1-Phosphate/ Fructose 6-phosphate 1.1194 0.8806
Glucose 6-Phosphate 1.1597 0.8403
Glucuronate/Galacturonate_01 0.9797 1.0203
Glucuronate/Galacturonate_02 1.0409 0.9591
Glutamate 1.0304 0.9696
Glutamine 1.0392 0.9608
Glutarate 0.8650 1.1350
Glutarylcarnitine(C5:1-DC Carnitine) 0.7143 1.2857
Glutathione oxidized 0.9283 1.0717
Glutathione Reduced 1.0654 0.9346
Glyceraldehyde 3-Phosphate 1.0324 0.9676
Glycerate 0.9744 1.0256
Glycero-3-Phosphocholine 0.8702 1.1298
Glycerol 0.9804 1.0196
Glycerol 3-Phosphate/Glycerol 1-Phosphate 0.9575 1.0425
Glycerophosphocholine 0.8828 1.1172
Glycine 0.8681 1.1319
Glycocholate 0.8243 1.1757
Guanidinoacetate 0.8877 1.1123
Guanidinopropionic acid 1.0137 0.9863
Guanidinosuccinate 1.1679 0.8321
Guanosine 0.8867 1.1133
Guanosine Diphosphate Mannose(GDP-mannose) 0.9512 1.0488
Guanosine Monophosphate 0.9861 1.0139
Guanosine Triphosphate 1.0080 0.9920
Heptanoate 1.2254 0.7746
Hexose 1.3351 0.6649
Hexose_02 0.9820 1.0180
Hexose phosphate 1.0667 0.9333
Hippurate 1.9201 0.0799
Histidine 0.9506 1.0494
Homocitrulline 1.2851 0.7149
Hypotaurine 0.4992 1.5008
Hypoxanthine 0.8474 1.1526
Imidazolepropionic acid 1.2161 0.7839
Indole-3-lactate 0.8168 1.1832
Indoxyl Sulfate 0.8915 1.1085
Inosine 0.7440 1.2560
Inosine-Monophosphate 0.7926 1.2074
Isobutyrate/Butyrate/Acetoin 0.7351 1.2649
Isoleucine 0.8734 1.1266
Lactate/Glyceraldehyde 0.9151 1.0849
Lactoylglutathione 1.6328 0.3672
Lactoylleucine 0.7373 1.2627
Lactoylvaline 0.7610 1.2390
L-Carnitine 0.9415 1.0585
Linoleate 1.0561 0.9439
Lumichrome 0.9576 1.0424
Lysine 1.0834 0.9166
Malate 1.1192 0.8808
Malonate 0.9377 1.0623
Malonyl-L-carnitine(C3:0-DC Carnitine) 0.7139 1.2861
Methionine 0.8609 1.1391
Methyl 4-Aminobutyrate 1.1656 0.8344
Methyl Galactoside 0.9640 1.0360
Methylthioadenosine 1.0608 0.9392
Myoinositol 0.9853 1.0147
N-Acetylalanine 0.8981 1.1019
N-Acetylasparagine 0.5152 1.4848
N-Acetylaspartate 0.9495 1.0505
N-Acetylcysteine 0.9942 1.0058
N-Acetylglucosamine/N-Acetylgalactosamine 1.5608 0.4392
N-Acetylglucosamine -phosphate 0.9396 1.0604
N-Acetylglutamate 0.8882 1.1118
N-Acetylglycine 0.5918 1.4082
N-Acetylleucine 0.8037 1.1963
N-Acetylmethionine 0.8558 1.1442
N-Acetylneuraminate 1.1866 0.8134
N-Acetylphenylalanine 0.9824 1.0176
N-Acetyltryptophan 1.0443 0.9557
NAD+ 0.9075 1.0925
NADH 0.7555 1.2445
NADP 0.9902 1.0098
NADPH 1.0019 0.9981
N-Alpha-Acetyllysine 0.9770 1.0230
Nicotinamide 1.0125 0.9875
Nicotinamide Mononucleotide 0.9265 1.0735
Nicotinamide N-oxide 0.8875 1.1125
N-Methyl-2-pyridone-5-carboxamide 0.7246 1.2754
N,N-Dimethylarginine 1.1335 0.8665
N,N-Dimethylglycine 0.9106 1.0894
N,N,N-Trimethyllysine 0.9680 1.0320
Nonanoate 1.1666 0.8334
Norleucine/Leucine 0.8624 1.1376
Norvaline/Valine 0.8280 1.1720
Omega-Hydroxydodecanoate 1.1073 0.8927
Ophthalmate 0.7461 1.2539
Ornithine 0.8813 1.1187
Orotate 1.1388 0.8612
Oxoadipate 0.8990 1.1010
Oxoproline (Pyroglutamate) 1.0215 0.9785
Palmitate 0.9860 1.0140
Pantothenate 0.8978 1.1022
Pentose 5-phosphate/Ribose 5-phosphate/Xylulose 5-phosphate/Ribulose 5-phosphate 0.9157 1.0843
Petroselinate/Elaidate/Oleate 1.0401 0.9599
Phenylalanine 0.8803 1.1197
Phosphocreatine 0.9651 1.0349
Phosphoenolpyruvate (PEP) 1.1250 0.8750
Phosphoethanolamine 0.9819 1.0181
Phosphorylcholine 0.9464 1.0536
Pipecolate 1.0492 0.9508
Proline 0.9196 1.0804
Propanoate 0.8319 1.1681
Propionyl coenzyme A 1.2409 0.7591
Propionylglycine 0.6784 1.3216
Pseudouridine 0.8207 1.1793
Pyridoxal 1.0141 0.9859
Pyroglutamate (Oxoproline) 0.8215 1.1785
Riboflavin 0.7980 1.2020
Ribose 0.9522 1.0478
Saccharate/Galactarate 0.8917 1.1083
Saccharopine 0.7112 1.2888
S-Adenosylhomocysteine 0.8646 1.1354
S-Adenosylmethionine 1.1680 0.8320
SAICAR 0.7920 1.2080
Sarcosine 0.8579 1.1421
Serine 0.9407 1.0593
Serotonin 0.9981 1.0019
Sorbitol/Mannitol/Galactitol/Hexitol 0.8338 1.1662
Stearate 0.9411 1.0589
Suberate 1.2858 0.7142
Succinate 0.9608 1.0392
Tartrate 0.9565 1.0435
Taurine 1.0405 0.9595
Thiamine 1.0605 0.9395
Thiamine Pyrophosphate 0.8958 1.1042
Thymidine 0.8606 1.1394
Trans-1,2-Cyclohexanediol/Hexanoate 0.8817 1.1183
Trans-hydroxyproline/Cis-hydroxyproline 0.7357 1.2643
Trimethylacetic acid/Pentanoate 0.7358 1.2642
Trimethylamine N-oxide 1.5242 0.4758
Tryptophan 0.9062 1.0938
Tyrosine 0.9094 1.0906
Uracil 0.6122 1.3878
Urate 0.8912 1.1088
Ureidopropionate 0.9757 1.0243
Uridine 0.8314 1.1686
Uridine Diphosphate Glucose/Uridine diphosphate galactose 1.1846 0.8154
Uridine Diphosphate Glucuronate 0.8694 1.1306
Uridine Diphosphate-N-Acetylglucosamine/Uridine Diphosphate-N-Acetylgalactosamine 0.9287 1.0713
Uridine Monophosphate 0.9003 1.0997
Ursodeoxycholate/Chenodeoxycholate/Deoxycholate 0.7491 1.2509
Xanthine 0.8598 1.1402
Xanthosine 0.8234 1.1766
Xylitol/Ribitol/Arabitol 0.9967 1.0033
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Factors:

F1Sample source:Liver | Genotype:S209A
F2Sample source:Liver | Genotype:wild type
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