Data for (Study ST003274)
(Analysis AN005361)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|
| 2-Aminoadipate | 1.0010 | 1.0068 | 1.0062 | 0.9945 | 1.0046 | 0.9929 | 1.0149 | 1.0003 | 0.9901 | 1.0006 |
| 2-Hydroxy-2-methylbutyrate | 1.0044 | 0.9929 | 0.9961 | 0.9982 | 0.9943 | 0.9955 | 1.0000 | 1.0305 | 1.0147 | 0.9929 |
| 2-Hydroxyglutarate | 0.9909 | 0.9965 | 0.9685 | 1.0056 | 1.0062 | 1.0028 | 0.9891 | 1.0029 | 0.9963 | 1.0049 |
| 2-Isopropylmalate | 0.9966 | 0.9674 | 1.0714 | 0.9899 | 1.0118 | 1.0069 | 1.0043 | 0.9675 | 1.0252 | 1.0227 |
| 2-Ketohexanoate | 1.0017 | 0.9962 | 0.9540 | 1.0053 | 1.0034 | 0.9980 | 0.9819 | 1.0100 | 0.9937 | 1.0035 |
| 3-Hydroxybutyrate | 0.9959 | 0.9946 | 0.9868 | 1.0025 | 1.0180 | 1.0026 | 0.9962 | 1.0146 | 0.9985 | 0.9905 |
| 3-Hydroxykynurenine | 1.0022 | 1.0359 | 0.9492 | 1.0210 | 0.9667 | 1.0532 | 0.9328 | 0.9803 | 0.9759 | 0.9722 |
| 3-Methyl-2-oxobutyrate | 0.9991 | 1.0041 | 0.9840 | 1.0152 | 0.9665 | 0.9737 | 1.0006 | 1.0023 | 1.0465 | 1.0008 |
| 3-Phosphoglycerate | 0.9902 | 0.9939 | 0.9705 | 1.0062 | 1.0136 | 1.0049 | 0.9972 | 1.0120 | 1.0121 | 0.9892 |
| 3-Ureidopropionate | 0.9998 | 1.0034 | 1.0382 | 1.0008 | 0.9961 | 0.9993 | 0.9930 | 0.9942 | 0.9993 | 1.0011 |
| Acetyl-CoA | 1.0302 | 0.9749 | 1.0242 | 0.9798 | 0.9697 | 1.0063 | 0.9866 | 1.0102 | 1.0240 | 1.0174 |
| Adenosine diphosphate | 0.9998 | 0.9848 | 1.0176 | 1.0113 | 1.0076 | 1.0150 | 0.9986 | 0.9845 | 0.9897 | 0.9951 |
| Adenosine monophosphate | 0.9981 | 0.9848 | 1.0181 | 0.9991 | 1.0009 | 1.0044 | 1.0043 | 1.0039 | 1.0071 | 1.0036 |
| Adenosine triphosphate | 0.9901 | 0.9841 | 1.0044 | 1.0004 | 1.0093 | 1.0190 | 0.9862 | 0.9977 | 1.0041 | 1.0045 |
| Anthranilate | 0.9960 | 0.9924 | 1.0036 | 1.0134 | 0.9907 | 1.0073 | 0.9986 | 0.9960 | 0.9989 | 0.9976 |
| Arginosuccinate | 0.9801 | 1.0058 | 0.9905 | 1.0079 | 0.9977 | 0.9914 | 0.9997 | 1.0037 | 1.0069 | 1.0069 |
| Ascorbate | 0.9768 | 0.9488 | 1.1162 | 0.9714 | 0.9822 | 1.0286 | 0.9731 | 0.9989 | 1.0442 | 1.0585 |
| Biotin | 0.9566 | 0.9608 | 0.9264 | 1.0156 | 1.0262 | 1.0217 | 1.0029 | 1.0054 | 1.0110 | 1.0173 |
| Cholesterol sulfate | 0.9989 | 0.9718 | 1.0182 | 0.9900 | 1.0189 | 1.0010 | 0.9947 | 1.0073 | 1.0240 | 1.0100 |
| cis-Aconitic acid | 0.9994 | 1.0094 | 1.0154 | 0.9989 | 1.0030 | 1.0089 | 0.9958 | 0.9901 | 0.9936 | 0.9930 |
| Citraconate | 0.9895 | 1.0041 | 0.9722 | 1.0009 | 0.9952 | 1.0034 | 0.9992 | 1.0134 | 0.9942 | 1.0037 |
| Citrate | 1.0055 | 0.9945 | 0.9981 | 1.0028 | 0.9987 | 1.0020 | 1.0070 | 0.9962 | 0.9915 | 0.9992 |
| Deoxycholate | 0.9948 | 0.9965 | 0.8391 | 1.0147 | 1.0155 | 1.0086 | 1.0109 | 1.0099 | 0.9512 | 1.0016 |
| Erythrose 4-phosphate | 1.0021 | 0.9845 | 0.9843 | 0.9919 | 1.0055 | 1.0012 | 1.0021 | 1.0168 | 1.0135 | 1.0035 |
| Flavin Mononucleotide | 1.0147 | 0.9926 | 1.0213 | 1.0116 | 1.0062 | 0.9889 | 0.9995 | 0.9973 | 0.9996 | 0.9868 |
| Fructose 1,6-bisphosphate | 0.9801 | 0.9727 | 0.9843 | 1.0194 | 1.0190 | 1.0124 | 0.9837 | 1.0130 | 1.0233 | 0.9903 |
| Fructose 6-phosphate | 0.9999 | 0.9912 | 0.9898 | 0.9950 | 1.0008 | 1.0026 | 0.9970 | 1.0213 | 1.0010 | 1.0029 |
| Fumarate | 0.9956 | 1.0024 | 0.9725 | 1.0076 | 1.0134 | 1.0075 | 1.0012 | 1.0032 | 0.9713 | 0.9930 |
| Glucose | 1.0079 | 1.0166 | 0.9090 | 1.0358 | 0.9451 | 0.9390 | 1.0195 | 1.0579 | 0.9982 | 0.9966 |
| Glucose 6-phosphate | 1.0071 | 0.9907 | 0.9978 | 1.0020 | 1.0012 | 0.9949 | 0.9981 | 1.0099 | 1.0055 | 0.9974 |
| Glutarylcarnitine | 1.0005 | 0.9815 | 1.0936 | 1.0224 | 1.0349 | 0.9652 | 1.0210 | 0.9120 | 1.1133 | 0.9733 |
| Glutathione | 0.9868 | 1.0014 | 1.0152 | 1.0049 | 0.9972 | 1.0017 | 1.0018 | 0.9913 | 0.9966 | 1.0074 |
| Glyceraldehyde | 0.9808 | 1.0596 | 0.8711 | 1.0078 | 0.9983 | 1.0001 | 0.9568 | 1.0468 | 0.9936 | 0.9697 |
| Glyceraldehyde 3-phosphate | 0.9828 | 0.9878 | 1.0309 | 1.0061 | 1.0069 | 1.0041 | 1.0008 | 1.0153 | 0.9827 | 1.0081 |
| Guanidoacetate | 1.0212 | 1.0131 | 1.0341 | 0.9943 | 0.9827 | 0.9845 | 0.9948 | 0.9874 | 0.9921 | 1.0062 |
| Homocysteate | 1.0154 | 0.9919 | 1.0905 | 1.0184 | 0.9919 | 0.9979 | 0.9469 | 1.0264 | 0.9750 | 0.9905 |
| Hydroxyisocaproate | 1.0013 | 1.0109 | 0.9896 | 0.9926 | 0.9926 | 0.9841 | 1.0015 | 1.0067 | 1.0119 | 1.0062 |
| Inosine | 0.9852 | 0.9938 | 0.9860 | 1.0087 | 0.9986 | 1.0088 | 1.0017 | 1.0077 | 1.0016 | 0.9991 |
| Isocitrate | 0.9879 | 1.0010 | 1.0052 | 0.9966 | 1.0130 | 1.0145 | 1.0026 | 0.9826 | 0.9947 | 1.0025 |
| Kynurenine | 0.9978 | 0.9799 | 1.0127 | 0.9835 | 0.9885 | 1.0018 | 1.0106 | 1.0380 | 1.0128 | 1.0149 |
| Lactate | 1.0063 | 1.0071 | 1.0202 | 1.0021 | 0.9935 | 0.9921 | 0.9929 | 0.9998 | 0.9998 | 0.9974 |
| Lactulose | 0.9959 | 0.9999 | 1.0431 | 1.0081 | 1.0089 | 0.9982 | 0.9849 | 1.0210 | 1.0023 | 0.9840 |
| Malate | 0.9986 | 1.0089 | 0.9897 | 1.0037 | 1.0028 | 1.0007 | 0.9961 | 0.9962 | 0.9974 | 0.9930 |
| Malonate | 0.9982 | 0.9889 | 0.9916 | 1.0036 | 1.0141 | 1.0027 | 1.0017 | 1.0158 | 0.9985 | 0.9914 |
| Malonyl-coenzyme A | 1.0278 | 0.9666 | 1.0787 | 0.9869 | 0.9720 | 1.0161 | 0.9908 | 1.0043 | 1.0033 | 1.0151 |
| Mevalonate | 1.0115 | 1.0076 | 1.1228 | 1.0120 | 1.0040 | 0.9943 | 1.0148 | 0.9174 | 0.9805 | 1.0004 |
| N-Acetyl-L-Alanine | 1.0018 | 1.0007 | 0.9975 | 0.9946 | 1.0074 | 0.9959 | 1.0136 | 1.0070 | 0.9944 | 0.9978 |
| N-Carbamoyl-L-aspartate | 1.0042 | 0.9997 | 1.0169 | 1.0172 | 1.0143 | 1.0184 | 0.9820 | 0.9528 | 0.9994 | 0.9820 |
| Nicotinamide adenine dinucleotide | 0.9950 | 0.9876 | 1.0365 | 1.0022 | 0.9905 | 1.0109 | 1.0113 | 0.9785 | 1.0042 | 1.0091 |
| Nicotinamide adenine dinucleotide phosphate | 1.0227 | 1.0203 | 1.0219 | 0.9801 | 0.9891 | 1.0014 | 1.0195 | 0.9691 | 1.0056 | 0.9938 |
| Nicotinate | 1.0195 | 0.9715 | 0.9077 | 0.9888 | 1.0251 | 0.9966 | 0.9648 | 0.9704 | 1.0522 | 1.0162 |
| Oxaloacetate | 1.0093 | 1.0175 | 0.9761 | 0.9692 | 1.0097 | 0.9933 | 1.0172 | 0.9825 | 0.9946 | 1.0150 |
| Oxidized glutathione | 1.0034 | 1.0190 | 0.9987 | 1.0095 | 0.9890 | 0.9949 | 1.0044 | 0.9940 | 0.9920 | 0.9870 |
| p-aminobenzoate | 1.0048 | 1.0038 | 0.9975 | 1.0068 | 0.9842 | 1.0076 | 0.9988 | 0.9933 | 1.0101 | 0.9891 |
| Phenyllactic acid | 1.0098 | 1.0636 | 0.9665 | 1.0006 | 0.9725 | 0.9582 | 1.0186 | 0.9793 | 1.0025 | 0.9906 |
| Phosphoenolpyruvate | 0.9969 | 1.0152 | 1.0016 | 1.0049 | 1.0141 | 0.9935 | 1.0048 | 0.9775 | 0.9816 | 0.9969 |
| Prephenate | 1.0196 | 0.9700 | 1.0609 | 0.9851 | 0.9643 | 1.0173 | 0.9786 | 1.0089 | 1.0181 | 1.0217 |
| Pyroglutamate | 0.9913 | 1.0063 | 0.9951 | 0.9943 | 0.9926 | 0.9994 | 1.0243 | 0.9913 | 1.0030 | 1.0070 |
| Pyrophosphate | 1.0134 | 1.0219 | 1.0167 | 0.9851 | 1.0011 | 0.9949 | 1.0002 | 1.0040 | 0.9919 | 0.9909 |
| Reduced nicotinamide Adenine Dinucleotide | 1.0047 | 1.0065 | 1.0289 | 0.9918 | 0.9783 | 1.0080 | 1.0122 | 0.9963 | 0.9937 | 1.0037 |
| Reduced nicotinamide adenine dinucleotide phosphate | 1.0048 | 0.9916 | 1.0038 | 1.0020 | 1.0030 | 0.9987 | 1.0196 | 0.9802 | 1.0141 | 0.9960 |
| Saccharopine | 0.9923 | 0.9974 | 1.0030 | 1.0081 | 1.0084 | 1.0002 | 0.9985 | 0.9989 | 0.9995 | 0.9961 |
| S-adenosyl-L-homocysteine | 1.0096 | 1.0270 | 0.9741 | 0.9838 | 0.9778 | 0.9841 | 0.9961 | 1.0257 | 1.0064 | 1.0019 |
| Succinate | 1.0010 | 0.9991 | 0.9911 | 0.9951 | 1.0013 | 1.0087 | 1.0019 | 0.9855 | 1.0052 | 1.0018 |
| Taurodeoxycholate | 0.9832 | 0.9621 | 1.0138 | 0.9878 | 1.0365 | 1.0535 | 0.9416 | 0.9934 | 0.9645 | 1.0307 |
| Thiamine pyrophosphate | 0.9956 | 1.0033 | 0.9652 | 0.9898 | 1.0030 | 0.9997 | 0.9985 | 0.9986 | 0.9975 | 1.0143 |
| Thymidine | 1.0073 | 1.0161 | 0.9703 | 0.9956 | 0.9833 | 0.9742 | 0.9991 | 1.0160 | 1.0009 | 1.0094 |
| Uracil | 1.0127 | 0.9750 | 0.9649 | 1.0126 | 0.9951 | 1.0141 | 0.9731 | 0.9983 | 0.9877 | 1.0062 |
| Urate | 0.9964 | 0.9903 | 0.9795 | 1.0033 | 0.9983 | 1.0044 | 1.0090 | 1.0074 | 1.0025 | 0.9999 |
| Uridine 5^-diphosphate | 1.0160 | 0.9831 | 1.0219 | 0.9989 | 0.9899 | 0.9991 | 0.9945 | 1.0182 | 0.9897 | 1.0049 |
| Uridine diphosphate-N-acetylglucosamine | 0.9745 | 0.9767 | 0.9276 | 0.9865 | 1.0137 | 1.0230 | 1.0135 | 0.9998 | 1.0803 | 0.9983 |
| Xanthosine | 1.1277 | 1.0153 | 1.1833 | 0.9886 | 1.0646 | 0.8779 | 1.0269 | 0.9894 | 0.9475 | 0.9530 |
| Xanthurenate | 0.9987 | 0.9579 | 1.0551 | 1.0098 | 0.9999 | 1.0089 | 1.0042 | 1.0065 | 1.0072 | 1.0066 |
Factors:
| F1 | Condition:Donor | Sex:F |
| F2 | Condition:Donor | Sex:M |
| F3 | Condition:ICM-DM | Sex:F |
| F4 | Condition:ICM-DM | Sex:M |
| F5 | Condition:ICM-No DM | Sex:F |
| F6 | Condition:ICM-No DM | Sex:M |
| F7 | Condition:NICM-DM | Sex:F |
| F8 | Condition:NICM-DM | Sex:M |
| F9 | Condition:NICM-No DM | Sex:F |
| F10 | Condition:NICM-No DM | Sex:M |