Data for (Study ST003327)
(Analysis AN005450)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 | F21 | F22 | F23 | F24 | F25 | F26 | F27 | F28 | F29 | F30 | F31 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
(11E)-Octadecenoic acid | 0.5827 | 0.6292 | 0.3814 | 0.1467 | 0.5510 | 0.6285 | 0.6721 | 0.6133 | 0.7236 | 0.5762 | 2.2355 | 1.2485 | 1.0924 | 2.4552 | 0.8118 | 0.3398 | 0.8918 | 1.1212 | 0.8590 | 0.9035 | 0.7844 | 1.1091 | 0.7820 | 1.1730 | 0.9884 | 1.2424 | 1.4020 | 1.4458 | 0.8341 | 0.9038 | 0.9917 |
2-3-Bisphospho-D-glycerate | 0.0424 | 0.0313 | 0.1208 | NA | 0.2159 | 0.0318 | 0.0002 | 0.0091 | 0.0010 | NA | 0.0114 | 0.0221 | NA | 0.0117 | 0.0029 | NA | 0.0105 | 0.0017 | 0.1069 | 17.9125 | 0.0009 | 0.0027 | 0.0064 | 0.0168 | 0.0215 | 0.0084 | 0.0494 | NA | 0.0025 | 0.0228 | NA |
2-Oxoglutarate | 1.7020 | 0.8822 | 1.2331 | 1.0862 | 1.0492 | 1.1236 | 1.0349 | 0.6510 | 0.8259 | 0.1882 | 1.2196 | 0.9122 | 1.4233 | 2.5252 | 0.9400 | 0.2420 | 0.8006 | 0.8895 | 1.0231 | 0.8462 | 1.0017 | 0.7627 | 0.7559 | 0.9902 | 0.8467 | 0.7686 | 1.0796 | 1.0296 | 0.7019 | 1.0417 | 0.9148 |
3-Phospho-D-glycerate | 1.5613 | 0.1647 | 4.2120 | NA | 0.0856 | NA | 0.0450 | 0.9622 | NA | NA | 0.2084 | 0.0750 | NA | 0.0227 | NA | NA | 0.0065 | 0.0072 | 4.5057 | 0.4310 | NA | NA | 0.0057 | 1.6673 | 0.0119 | 0.0348 | NA | NA | NA | 0.0085 | NA |
4-Pyridoxate | 0.9981 | 1.3663 | 0.9211 | 1.2779 | 1.4527 | 1.9252 | 0.4769 | 1.1561 | 1.0547 | 1.0888 | 0.7926 | 0.7107 | 0.7718 | 0.9181 | 1.3719 | 0.5755 | 0.7585 | 0.5857 | 0.9360 | 0.9764 | 0.6292 | 0.7320 | 0.7211 | 1.0352 | 0.7337 | 0.6860 | 1.3394 | 0.6233 | 0.5693 | 0.9712 | 0.4344 |
(4Z-7Z-10Z-13Z-16Z-19Z)-Docosahexaenoic acid | 0.8604 | 0.8693 | 0.7285 | 0.2132 | 1.0939 | 0.9793 | 1.0010 | 0.4436 | 0.5735 | 0.3712 | 1.5284 | 1.1015 | 0.4481 | 1.9908 | 0.5815 | 0.2391 | 0.8708 | 0.8695 | 1.0499 | 1.0958 | 0.7204 | 0.9447 | 0.6949 | 1.3616 | 1.0859 | 0.9692 | 1.5127 | 0.4732 | 0.6693 | 0.6706 | 0.5887 |
5-6-Dihydrothymine | 0.9592 | 0.9699 | 1.3094 | 0.8910 | 0.9472 | 1.0117 | 1.0777 | 0.9159 | 1.3302 | 0.8278 | 1.0057 | 0.8717 | 0.7670 | 1.1640 | 1.0081 | 1.1375 | 0.9168 | 0.9597 | 0.9879 | 1.0262 | 0.8630 | 1.0143 | 1.0561 | 0.9010 | 0.9334 | 0.8900 | 1.2766 | 0.6141 | 0.9130 | 1.0631 | 1.2070 |
5-Deoxyribose-1-phosphate | 0.9712 | 0.9700 | 0.6556 | 0.5172 | 0.8935 | 0.9019 | 0.5883 | 0.7919 | 0.8173 | 0.4866 | 0.8971 | 0.9313 | 0.6910 | 0.9400 | 1.0598 | 0.5272 | 0.8153 | 0.8874 | 1.2229 | 0.8150 | 0.8612 | 0.9891 | 0.8948 | 1.8645 | 0.8391 | 0.9451 | 1.5012 | 0.7664 | 0.7910 | 0.9548 | 0.5961 |
(5Z-7E-9E-14Z-17Z)-Eicosapentaenoic acid | 1.4311 | 0.7184 | 0.3715 | 0.1282 | 1.0494 | 0.7310 | 0.4592 | 0.4079 | 0.6271 | 0.1666 | 2.0121 | 1.0867 | 0.2161 | 1.3285 | 0.8191 | 0.1670 | 0.8475 | 0.8269 | 1.0668 | 0.9570 | 0.4368 | 0.8983 | 0.5563 | 1.2421 | 1.0386 | 1.1245 | 1.5544 | 0.4503 | 0.5833 | 0.5640 | 0.3488 |
(5Z-8Z-11Z-14Z-17Z)-Icosapentaenoic acid | 0.8073 | 1.6322 | 0.6958 | 0.6801 | 0.7472 | 0.5403 | 3.3227 | 0.8242 | 0.6315 | NA | 1.1064 | 0.7470 | 0.0329 | 5.9695 | 0.7552 | 0.0226 | 1.1079 | 0.6219 | 0.8461 | 0.6426 | 3.7339 | 0.7855 | 0.3698 | 0.9386 | 1.1247 | 1.2713 | 0.8624 | 0.1739 | 0.7031 | 0.7049 | NA |
(5Z-8Z-11Z-14Z)-Icosatetraenoic acid | 0.5630 | 0.5857 | 0.2200 | 0.1876 | 0.6908 | 0.6602 | 0.5007 | 0.3976 | 0.4761 | 0.2204 | 1.6196 | 1.0458 | 0.1881 | 11.4251 | 0.4719 | 0.2189 | 0.7014 | 0.7782 | 0.7683 | 0.6708 | 0.3070 | 0.7646 | 0.5217 | 1.0745 | 0.8528 | 0.9098 | 1.1875 | 0.4283 | 0.5148 | 0.6996 | 0.3654 |
6-Phospho-D-gluconate | 1.0303 | 0.7765 | 0.2832 | 1.5379 | 1.5323 | 1.0631 | 4.5445 | 0.5053 | 0.5960 | 0.1270 | 1.8738 | 0.9066 | 0.3641 | 5.4847 | 0.8915 | 0.2523 | 0.7230 | 0.8037 | 0.7659 | 0.6843 | 0.9080 | 0.9762 | 0.7125 | 1.0796 | 0.5939 | 0.7392 | 0.8272 | 0.2732 | 0.5360 | 1.3867 | 0.3049 |
(6Z-9Z-12Z)-Octadecatrienoic acid | 0.6715 | 0.7548 | 0.6602 | 0.2072 | 0.6342 | 0.6117 | 0.5894 | 0.3754 | 0.6649 | 0.1952 | 2.0632 | 1.3842 | 0.5206 | 3.2385 | 0.6058 | 0.1772 | 0.9007 | 1.0471 | 0.8730 | 0.8835 | 0.5860 | 0.8097 | 0.6984 | 1.1893 | 1.1417 | 1.0331 | 1.6491 | 0.4569 | 0.5983 | 0.7646 | 0.3264 |
(7Z-10Z-13Z-16Z-19Z)-Docosa-7-10-13-16-19-pentaenoic acid | 0.6940 | 0.7860 | 0.3006 | 0.1322 | 0.8701 | 0.8516 | 0.5235 | 0.4698 | 0.6235 | 0.2986 | 1.8808 | 1.2203 | 0.2628 | 1.8955 | 0.6486 | 0.1873 | 0.8807 | 0.9903 | 0.9788 | 0.9443 | 0.6234 | 1.0369 | 0.6626 | 1.2974 | 1.0445 | 1.0675 | 1.6638 | 0.5622 | 0.6650 | 0.7857 | 0.5754 |
9-cis-11-trans-Octadecadienoate | 0.5924 | 0.6232 | 0.5299 | 0.1025 | 0.5729 | 0.6144 | 0.9581 | 0.4747 | 0.6951 | 0.3235 | 1.8959 | 1.2019 | 0.3957 | 6.3993 | 0.6359 | 0.1783 | 0.7773 | 0.9756 | 0.8293 | 0.7886 | 0.6842 | 0.9715 | 0.7132 | 1.0516 | 0.9741 | 0.9788 | 1.4023 | 0.6906 | 0.6788 | 0.8874 | 0.4516 |
9-Oxononanoic acid | 1.0630 | 1.0717 | 1.2612 | 0.7564 | 0.9767 | 1.0050 | 0.8868 | 0.8894 | 0.9071 | 0.7711 | 0.9864 | 0.9447 | 0.9373 | 1.0330 | 0.9740 | 0.9175 | 0.9991 | 1.0011 | 1.0717 | 0.9736 | 1.4087 | 0.9473 | 1.0499 | 1.0309 | 1.0115 | 1.0055 | 1.0097 | 1.1341 | 0.9061 | 0.9928 | 0.5282 |
(9Z)-Hexadecenoic acid | 0.8378 | 0.6351 | 0.4993 | 0.0732 | 0.5434 | 0.6226 | 0.4897 | 0.5770 | 0.7462 | 0.5046 | 2.1332 | 1.5461 | 0.7918 | 1.3449 | 0.5923 | 0.3589 | 1.0193 | 1.2242 | 0.7880 | 1.0010 | 0.9274 | 1.0675 | 0.6982 | 1.3330 | 1.0826 | 1.1094 | 1.4918 | 1.1490 | 0.7162 | 0.5688 | 0.9065 |
Adenine | 3.3656 | 4.5385 | NA | NA | 0.0698 | 0.2119 | NA | 0.0684 | 0.0282 | NA | 0.0362 | 0.1582 | NA | 0.0862 | 0.0466 | NA | 0.0733 | 0.1593 | 0.1522 | 0.4255 | NA | 0.1339 | 0.0935 | 2.4730 | 0.1229 | 0.2377 | 0.3714 | NA | 0.0776 | 0.3887 | NA |
Adenosine | 0.8568 | 1.0966 | NA | 0.2014 | 0.2709 | 0.7802 | NA | 0.6897 | 15.3467 | NA | 0.0784 | 0.6995 | NA | 0.1066 | 1.1099 | NA | 0.4687 | 0.5503 | 0.0323 | 0.0521 | NA | 0.4797 | 0.4066 | 0.4139 | 0.7641 | 0.2818 | 0.5622 | NA | 0.6028 | 1.8276 | NA |
ADP | 0.3358 | 0.3414 | 0.2162 | NA | 0.3436 | 0.4108 | 0.1740 | 0.3758 | 0.3666 | 0.6117 | 0.2700 | 0.7001 | 0.2084 | 0.3197 | 0.3219 | 0.2906 | 0.4165 | 0.2991 | 1.1427 | 8.1245 | 0.2475 | 0.3145 | 0.3077 | 1.0587 | 4.3096 | 0.2875 | 0.3685 | 0.2645 | 0.3222 | 0.3157 | 0.2879 |
ADP-ribose | 0.2730 | 0.7077 | NA | NA | 0.5450 | 0.0324 | NA | 0.2421 | 0.0071 | NA | 4.1612 | NA | NA | 1.1545 | NA | NA | 0.1443 | 5.1665 | NA | 3.2442 | NA | 1.8377 | 0.0310 | 0.0973 | NA | 0.0549 | 0.0811 | 0.5852 | 0.1273 | 1.5670 | NA |
AMP | 2.2242 | 1.1778 | 0.4356 | NA | 1.2479 | 0.5157 | 0.1646 | 1.4688 | 0.4746 | NA | 0.6353 | 0.5702 | 0.5531 | 0.6563 | 0.9656 | 0.8484 | 0.8292 | 0.5605 | 0.4798 | 1.3355 | 0.2472 | 0.4687 | 0.5009 | 0.4520 | 0.8325 | 1.2464 | 0.7797 | 0.5861 | 1.2368 | 0.4726 | 33.9710 |
Ascorbate | 1.1077 | 0.8844 | 0.5566 | 0.8572 | 0.9138 | 1.0161 | 0.9735 | 0.6562 | 0.7585 | 0.5752 | 0.8935 | 0.7732 | 0.8162 | 1.1817 | 0.7343 | 0.7111 | 0.7157 | 0.7276 | 0.9169 | 1.6888 | 0.6165 | 0.8109 | 0.6741 | 0.9596 | 2.5257 | 0.7559 | 0.9131 | 0.4815 | 0.6950 | 0.9432 | 0.7221 |
ATP | 0.0489 | 0.0648 | NA | NA | 0.0231 | 0.0895 | 0.0251 | 0.0565 | 0.0583 | NA | 0.0452 | 0.0875 | NA | 0.0526 | 0.0915 | NA | 0.0374 | 0.0615 | 0.0134 | 0.3701 | NA | 0.0484 | 0.0670 | 0.0597 | 10.9480 | 1.6135 | 0.0730 | NA | 0.0701 | 0.0248 | NA |
Butanoic acid | 1.1359 | 1.1106 | 0.6391 | 0.7190 | 0.9574 | 1.0046 | 0.9218 | 0.8299 | 1.0408 | 1.2702 | 0.9504 | 0.8910 | 0.7725 | 1.0138 | 0.9729 | 0.7066 | 0.8685 | 0.9535 | 1.0260 | 0.9973 | 1.3354 | 0.8733 | 1.0111 | 1.0980 | 1.0450 | 0.8774 | 1.2118 | 0.9109 | 0.8164 | 0.9728 | 1.0496 |
Citrate | 0.9714 | 2.6172 | 0.6661 | 0.7994 | 0.8053 | 0.8229 | 0.9671 | 0.6521 | 0.7180 | 0.6559 | 0.8863 | 0.7398 | 0.6092 | 1.1621 | 0.7521 | 0.7055 | 0.6863 | 0.7228 | 0.8788 | 1.2862 | 0.7830 | 0.7773 | 0.6839 | 0.9102 | 1.3348 | 0.7614 | 0.8624 | 0.6203 | 0.6616 | 0.8616 | 0.7137 |
D-Arabitol | 2.3858 | 1.1141 | 1.0115 | 1.2543 | 1.2499 | 1.0823 | 1.0974 | 0.2433 | 0.2777 | 0.2488 | 0.5998 | 0.4101 | 0.3727 | 0.6004 | 0.3330 | 0.1907 | 0.3230 | 0.3036 | 1.4319 | 4.1078 | 0.5959 | 0.2811 | 0.2618 | 1.6156 | 0.8686 | 0.9148 | 0.8451 | 0.3898 | 0.2325 | 0.3508 | 0.2823 |
Decanoic acid | 1.0189 | 1.0781 | 1.3620 | 0.8667 | 1.0879 | 1.1418 | 1.6834 | 0.9795 | 0.9184 | 1.0126 | 1.0819 | 0.8898 | 0.9509 | 1.1993 | 1.0441 | 1.5360 | 0.8849 | 0.8543 | 0.9928 | 1.0948 | 2.5386 | 0.9305 | 0.9117 | 1.0386 | 1.0392 | 0.9088 | 0.9457 | 1.2131 | 0.9569 | 0.9042 | 0.8467 |
Dehydroascorbate | 0.7955 | 0.9885 | 0.7698 | 0.3542 | 0.7625 | 0.7556 | 1.0781 | 0.3121 | 10.7229 | 0.2728 | 0.6019 | 0.5458 | 0.3280 | 0.5148 | 0.3425 | 0.3311 | 0.3619 | 0.4633 | 0.6209 | 0.8050 | 0.5085 | 0.3564 | 0.3555 | 0.7152 | 1.1453 | 0.5416 | 0.7071 | 0.3806 | 0.3009 | 0.3833 | 0.3304 |
D-Erythrose 4-phosphate | NA | 0.8627 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.1373 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
D-Fructose 1-6-bisphosphate | 0.0053 | 0.0293 | NA | NA | 0.0062 | 0.1297 | NA | NA | NA | NA | 0.0132 | 0.0110 | NA | 0.0852 | 0.0784 | NA | 0.0180 | 40.6176 | 0.0029 | 0.0130 | NA | NA | 0.0000 | 0.0323 | 0.0637 | 0.0488 | 0.0156 | NA | 0.0214 | 0.0003 | NA |
D-Glucose | 1.1505 | 1.1984 | 0.6647 | 0.6166 | 0.9868 | 0.9491 | 0.6073 | 0.7882 | 1.2335 | 0.6445 | 0.9319 | 0.8450 | 0.6550 | 1.0351 | 0.8772 | 0.8543 | 0.8164 | 0.8700 | 1.0750 | 1.0349 | 1.1836 | 0.8180 | 0.8433 | 0.9734 | 1.0913 | 0.8652 | 1.4230 | 0.7326 | 0.7578 | 0.9564 | 0.6415 |
D-Glucose 6-phosphate | 1.4298 | 1.8227 | 1.6273 | NA | 1.0595 | 3.1346 | NA | 0.2536 | 0.4755 | NA | 0.5221 | 0.3158 | 0.0736 | 2.8634 | 0.3558 | 0.1988 | 0.2489 | 0.2435 | 0.7451 | 0.4091 | NA | 0.4767 | 0.2799 | 1.2813 | 0.3308 | 0.4784 | 1.9749 | NA | 0.6150 | 0.4563 | 0.3335 |
D-Glyceraldehyde 3-phosphate | 0.8077 | 0.8287 | 15.1611 | 0.6185 | 1.0257 | 0.8189 | 2.0133 | 1.2910 | 1.0891 | 1.8913 | 1.0075 | 0.7703 | 1.5543 | 1.1784 | 1.2728 | 1.8822 | 1.1740 | 0.8505 | 0.9312 | 0.6309 | 2.4879 | 1.3575 | 1.0596 | 0.6747 | 0.8664 | 0.9879 | 1.3687 | 1.0759 | 1.0889 | 1.0066 | 1.3493 |
Diphosphate | 1.6312 | 1.3584 | 0.6726 | 0.7705 | 0.9624 | 0.9918 | 0.7398 | 0.8504 | 1.0460 | 0.3101 | 0.9422 | 1.0714 | 0.7554 | 1.1872 | 1.0994 | 0.9076 | 0.8924 | 0.9798 | 1.0812 | 1.0633 | 1.0271 | 0.6193 | 0.6057 | 0.9885 | 0.8936 | 0.7950 | 1.0127 | 0.4989 | 0.6826 | 0.7014 | 0.0107 |
Dodecanoic acid | 0.8881 | 1.1457 | 0.7777 | 0.1791 | 0.9752 | 1.0101 | 0.4969 | 0.5760 | 0.7835 | 0.4415 | 1.3073 | 1.0884 | 0.4167 | 0.7114 | 0.5029 | 0.5661 | 0.7559 | 0.8811 | 0.9260 | 1.4554 | 0.7539 | 0.7572 | 0.7422 | 1.1428 | 1.6696 | 0.9258 | 1.3413 | 0.7368 | 0.6399 | 0.5641 | 0.6576 |
D-Rhamnose | 1.6325 | 0.7333 | 1.5397 | 0.7431 | 0.9813 | 0.8379 | 1.3126 | 0.8122 | 0.7388 | 0.8659 | 1.3839 | 0.7812 | 0.6538 | 3.0615 | 0.7380 | 0.8528 | 0.9791 | 0.7408 | 0.9518 | 0.7573 | 1.2014 | 1.0991 | 0.8404 | 1.0215 | 0.7740 | 0.9249 | 1.0243 | 0.9964 | 0.9335 | 1.2123 | 0.8057 |
D-Ribose | 1.1919 | 1.5570 | 0.7052 | 0.5673 | 0.9693 | 0.9219 | 0.6241 | 0.7641 | 0.8203 | 0.5918 | 0.9127 | 0.8354 | 0.6613 | 1.0555 | 0.8529 | 0.7938 | 0.7909 | 0.8567 | 1.0545 | 1.1108 | 1.0999 | 0.7987 | 0.8409 | 0.9792 | 1.3787 | 0.8710 | 0.9926 | 0.6613 | 0.7166 | 0.9550 | 0.5988 |
D-Ribose 5-phosphate | 1.1673 | 0.9149 | 0.2184 | NA | 1.0364 | 0.8866 | NA | 0.7844 | 1.0728 | 0.4410 | 0.9906 | 0.8548 | 0.2362 | 1.0506 | 1.0808 | 0.3300 | 0.8935 | 0.8393 | 1.2996 | 0.9100 | 0.3742 | 0.9962 | 0.9331 | 1.5926 | 0.6761 | 0.8778 | 1.5519 | 0.5019 | 0.6434 | 0.9670 | 0.3575 |
Fumarate | 1.2939 | 1.1908 | 0.9941 | 0.7985 | 1.0812 | 1.0201 | 0.7326 | 0.8429 | 0.9399 | 0.9262 | 0.9266 | 0.8576 | 0.7672 | 0.9466 | 0.9355 | 0.8854 | 0.7838 | 0.9071 | 0.9658 | 1.0246 | 0.5629 | 0.9461 | 0.8985 | 1.0503 | 0.9813 | 0.9199 | 1.1576 | 0.9810 | 0.8938 | 0.9949 | 0.9538 |
GMP | 1.8635 | 1.3979 | 0.1065 | NA | 0.8493 | 1.7378 | NA | 0.6470 | 0.2677 | NA | 0.8671 | 1.2087 | NA | 1.1184 | 0.6302 | NA | 0.1810 | 0.2451 | 0.1882 | 0.7375 | NA | 0.6443 | 0.6674 | 3.3838 | 0.8997 | 1.1626 | 2.2681 | NA | 0.7290 | 0.1662 | NA |
Guanine | 0.2613 | 2.0530 | 0.0812 | 2.2650 | 1.6534 | 0.2747 | 0.5301 | 0.1359 | 0.1978 | NA | 0.4357 | 0.3996 | 0.1825 | 0.7462 | 0.1354 | 0.1336 | 0.2259 | 6.0845 | 0.2669 | 0.1676 | 0.9944 | 1.4993 | 0.2105 | 0.1773 | 4.5715 | 0.1958 | 0.3167 | 0.2044 | 0.5840 | 1.4260 | 0.1253 |
Guanosine | 1.9000 | 0.5988 | NA | NA | 0.1793 | 0.0331 | NA | 0.3343 | 0.1778 | NA | 0.0615 | 0.0035 | NA | 0.0117 | 0.0052 | 0.0722 | 0.0102 | 0.2632 | 0.1601 | 0.1197 | NA | 0.0802 | 0.0089 | 0.0202 | 0.1719 | 0.0072 | 0.0071 | NA | 0.0361 | 15.0375 | NA |
Heptanoic acid | 1.1244 | 1.0379 | 1.2407 | 0.6491 | 1.0677 | 0.9436 | 1.1619 | 0.8967 | 0.9618 | 0.2458 | 1.0188 | 0.8813 | 0.4133 | 1.0034 | 0.8812 | 0.3115 | 0.9893 | 0.9413 | 1.0031 | 1.0101 | 1.3512 | 1.0224 | 0.9286 | 1.1629 | 1.0110 | 1.0418 | 1.0569 | 0.3934 | 0.9571 | 0.9111 | 0.2613 |
Hexadecanoic acid | 0.6633 | 1.6477 | 0.5446 | 0.4192 | 0.5939 | 0.6331 | 0.5435 | 0.5418 | 3.3494 | 0.6761 | 1.1544 | 1.0030 | 0.4806 | 0.8715 | 0.5621 | 0.3102 | 0.6864 | 0.8293 | 0.7476 | 1.6311 | 0.6811 | 0.7555 | 0.6086 | 0.9762 | 1.0898 | 0.8541 | 1.0113 | 1.0145 | 0.6379 | 0.6732 | 1.1023 |
Hexanoic acid | 1.0571 | 1.0450 | 1.0215 | 0.8315 | 0.9888 | 0.9809 | 1.0648 | 0.9015 | 0.9622 | 0.6380 | 1.0055 | 0.9612 | 0.9311 | 1.0868 | 0.9799 | 0.7473 | 0.9634 | 0.9803 | 1.0343 | 0.9652 | 1.2948 | 0.9633 | 1.0072 | 1.0514 | 0.9905 | 1.0499 | 1.0174 | 0.9501 | 0.9603 | 0.9797 | 0.6744 |
Icosatrienoic acid | 0.6450 | 0.5454 | 0.2402 | NA | 0.5637 | 0.8039 | 0.6700 | 0.3238 | 0.3912 | 0.2383 | 3.9880 | 1.0957 | 0.3748 | 0.6221 | 0.5332 | 0.1480 | 0.5533 | 0.6303 | 0.8616 | 0.5926 | 0.3672 | 0.7149 | 0.5146 | 1.6540 | 0.9949 | 1.1722 | 2.4826 | 0.4459 | 0.5249 | 0.4424 | 0.3988 |
IMP | 0.1723 | 0.3391 | 0.0135 | NA | 0.7063 | 0.6926 | NA | 1.3419 | 0.2950 | NA | 0.2852 | 0.8272 | 0.8606 | 0.2953 | 0.2408 | 0.1977 | 0.5057 | 0.4925 | 0.3495 | 0.2752 | NA | 1.3561 | 6.8615 | 0.2621 | 0.7019 | 0.6086 | 0.4988 | NA | 0.2157 | 8.3303 | NA |
Inosine | 2.2482 | 1.3778 | 0.2735 | 1.1968 | 0.9925 | 1.4790 | 0.4835 | 0.3966 | 0.3630 | 0.2674 | 2.1713 | 0.8078 | 1.0166 | 0.5486 | 0.4467 | 0.2227 | 0.8542 | 0.8694 | 1.2678 | 0.7364 | 0.5071 | 0.4488 | 0.4957 | 0.9090 | 0.7949 | 0.5561 | 1.4699 | 0.8527 | 0.2856 | 0.4315 | 0.3937 |
Itaconate | 1.5794 | 2.2726 | 0.0849 | 0.0621 | 0.3030 | 0.2581 | NA | 0.3704 | 0.1294 | NA | 0.1953 | 0.2601 | 0.3144 | 0.1604 | 0.1072 | NA | 0.1243 | 0.2130 | 1.8684 | 3.0995 | 0.1779 | 0.4088 | 0.6876 | 2.8235 | 0.1330 | 0.1609 | 1.3540 | 0.0066 | 3.7478 | 0.0856 | NA |
Lactate | 1.6901 | 3.3973 | 0.6920 | 1.8392 | 1.0425 | 1.2552 | 0.6937 | 0.3149 | 0.3058 | 0.1935 | 0.7570 | 0.5788 | 0.6196 | 0.4548 | 0.3130 | 0.3383 | 0.4967 | 0.5441 | 0.9950 | 1.2919 | 0.6911 | 0.3046 | 0.3774 | 0.9855 | 1.2999 | 0.6334 | 0.9820 | 0.4821 | 0.2255 | 0.3994 | 0.2726 |
LPI(16:1) | 1.3754 | 0.9163 | 2.9254 | 0.3557 | 1.1498 | 1.1767 | 3.6965 | 0.3650 | 0.5506 | 0.4701 | 1.2691 | 1.1221 | 1.1026 | 0.8752 | 0.8945 | 0.4955 | 0.8076 | 0.7730 | 1.3095 | 1.0104 | 1.9088 | 0.6767 | 0.6448 | 2.0467 | 0.7938 | 1.0866 | 1.1366 | 0.3524 | 0.5007 | 0.4518 | 0.3144 |
LPI(18:1) | 1.1906 | 0.9977 | 2.4347 | 1.5806 | 1.2059 | 1.2357 | 3.4287 | 0.4729 | 0.6823 | 0.8922 | 1.2846 | 0.9082 | 1.0236 | 2.8061 | 0.8326 | 0.6786 | 0.6819 | 0.6409 | 1.3888 | 0.8013 | 1.3499 | 0.5923 | 0.6276 | 1.0373 | 0.8940 | 0.8939 | 1.1469 | 0.6599 | 0.5449 | 1.4722 | 0.5645 |
Malate | 2.2567 | 1.4155 | 1.1103 | 1.0998 | 1.0275 | 1.1840 | 1.1943 | 0.4084 | 0.4354 | 0.3320 | 0.6941 | 0.6084 | 0.4188 | 0.8041 | 0.4633 | 0.2531 | 0.4737 | 0.5303 | 1.0618 | 1.5545 | 0.7691 | 0.4528 | 0.4179 | 1.3433 | 1.9480 | 0.6344 | 1.1719 | 0.4811 | 0.3661 | 0.5004 | 0.2927 |
Maltotriose | 0.1444 | 4.6594 | NA | NA | 0.1546 | 0.8419 | 0.0160 | 0.0092 | 0.0388 | NA | 0.0483 | 0.3838 | NA | 0.0302 | 0.0312 | NA | 12.7276 | 1.3973 | 0.3499 | 0.1798 | NA | 0.0053 | 0.0145 | 0.1536 | 0.5652 | 0.1367 | 0.2578 | NA | NA | 0.0718 | NA |
Mannitol | 1.9292 | 1.3932 | 0.0347 | 0.0496 | 0.1807 | 0.0620 | 0.0347 | 0.0274 | 0.0555 | 0.0253 | 0.8442 | 0.5708 | 1.0122 | 0.0375 | 0.0524 | 0.0318 | 0.4653 | 0.3673 | 1.7996 | 2.4803 | 4.5351 | 0.1162 | 0.1736 | 1.8650 | 3.0142 | 0.6944 | 1.6020 | 2.4167 | 0.0636 | 0.5062 | 0.0295 |
Nicotinamide D-ribonucleotide | 0.1739 | 0.4808 | 0.0301 | 0.0157 | 0.1576 | 7.9663 | 0.1115 | 0.1044 | 0.1107 | 0.2467 | 0.1908 | 0.1747 | 0.2553 | 0.2447 | 0.2032 | 0.2645 | 0.1754 | 0.1429 | 0.3650 | 0.2588 | 0.0184 | 0.4158 | 0.1229 | 0.2024 | 0.0814 | 0.2493 | 5.4947 | 0.1675 | 0.9211 | 0.2596 | 0.3012 |
Nonanoic acid | 1.0860 | 1.0984 | 1.3359 | 0.7437 | 0.9769 | 1.0158 | 2.4320 | 0.9237 | 0.9475 | 0.4344 | 1.0208 | 0.9410 | 0.8953 | 0.9715 | 0.8193 | 0.3642 | 1.0625 | 0.9187 | 0.9767 | 0.9434 | 1.6790 | 1.0518 | 0.9243 | 1.1732 | 1.0683 | 0.9791 | 0.9742 | 0.5856 | 0.9602 | 0.8808 | 0.5858 |
Octadecanoic acid | 0.5587 | 0.5745 | 0.6443 | 0.2417 | 0.5343 | 0.5935 | 0.5700 | 0.5268 | 0.5904 | 0.4628 | 1.0507 | 0.8806 | 0.4330 | 0.8321 | 0.5085 | 0.2020 | 0.6366 | 0.6908 | 0.6618 | 6.9426 | 0.7010 | 0.7055 | 0.6228 | 0.8023 | 0.8309 | 0.7549 | 0.9699 | 0.3964 | 0.6169 | 0.5534 | 0.6635 |
Octanoic acid | 0.0806 | 0.6771 | 0.0565 | 0.0560 | 0.0611 | 0.7543 | 0.0620 | 0.0783 | 0.1039 | 0.0399 | 0.0773 | 0.6006 | 0.0639 | 0.2106 | 0.6661 | 0.0997 | 0.0649 | 0.6625 | 0.0995 | 0.9378 | 0.1965 | 0.0632 | 0.3976 | 0.1066 | 10.0698 | 0.0834 | 0.9365 | 0.1084 | 0.4601 | 1.1735 | 0.0301 |
Orthophosphate | 1.2717 | 1.1310 | 0.8044 | 0.8115 | 0.9988 | 0.9224 | 0.9938 | 0.8642 | 1.2597 | 0.5288 | 0.9839 | 0.9988 | 0.7656 | 1.2754 | 1.0865 | 0.9824 | 0.9125 | 0.9536 | 1.0178 | 1.0309 | 1.2332 | 0.7923 | 0.7793 | 0.9851 | 0.9341 | 0.9094 | 1.0946 | 0.6994 | 0.7925 | 0.8924 | 0.4998 |
Oxaloacetate | 1.0867 | 0.8775 | 0.5480 | 0.9520 | 0.9194 | 0.8709 | 0.8664 | 0.7155 | 0.8236 | 0.8282 | 0.9809 | 0.8240 | 0.5977 | 1.4506 | 0.8314 | 0.6472 | 0.7442 | 0.7937 | 1.0620 | 1.7154 | 0.8319 | 0.7739 | 0.6904 | 0.9889 | 2.0407 | 0.7785 | 0.9414 | 0.6040 | 0.7227 | 1.0310 | 0.6346 |
Pentanoate | 0.9187 | 0.9940 | 1.1636 | 0.9428 | 1.0011 | 0.9660 | 0.9711 | 1.1229 | 1.1635 | 1.3596 | 0.9404 | 0.9704 | 0.8861 | 1.2812 | 1.0990 | 1.0795 | 1.0401 | 0.9708 | 0.9113 | 0.9425 | 0.8272 | 1.1151 | 1.1216 | 0.8959 | 0.8748 | 1.0081 | 1.0380 | 0.6023 | 1.0286 | 1.0221 | 0.7725 |
Phosphoenolpyruvate | 0.1704 | 0.0102 | NA | NA | 0.0277 | NA | NA | 0.2353 | NA | NA | NA | 0.0710 | NA | 0.0325 | 1.6528 | NA | 0.0079 | 3.2470 | 0.0227 | 6.7399 | NA | NA | 0.0170 | 2.3665 | 0.0345 | NA | 0.1684 | NA | 0.1493 | NA | NA |
Pyridoxamine phosphate | 0.1028 | 0.3721 | 0.0003 | 0.0589 | 0.1557 | 16.2669 | 0.0034 | 0.0285 | 0.2535 | 0.0156 | 0.0533 | 0.0182 | 0.0078 | 0.2267 | 0.4122 | 0.0029 | 0.0609 | 0.0608 | 0.0703 | 0.5460 | NA | 0.2883 | 0.0823 | 0.1273 | 0.0370 | 0.0606 | 0.1170 | NA | 0.1368 | 0.0602 | 0.0067 |
Pyruvate | 0.8451 | 1.1227 | 0.4392 | 0.4505 | 0.7524 | 0.6571 | 0.5227 | 0.8780 | 8.1571 | NA | 0.6668 | 0.5898 | 0.4974 | 1.3406 | 0.5577 | 0.3438 | 0.6114 | 0.5530 | 0.8308 | 1.1078 | 0.5301 | 0.5169 | 0.4288 | 0.6399 | 0.8299 | 0.5975 | 0.7360 | 0.4305 | 0.5551 | 0.6757 | 2.1378 |
(R)-S-Lactoylglutathione | 0.8706 | 0.3900 | NA | NA | 0.1875 | 0.4769 | NA | NA | 0.8057 | NA | 6.7422 | 1.5289 | NA | 0.2100 | 0.2310 | NA | NA | NA | 0.3678 | 1.0962 | NA | NA | 1.1375 | 0.2109 | 0.2348 | 0.9912 | 0.5209 | NA | 0.1943 | NA | NA |
(S)-2-Hydroxyglutarate | 0.7616 | 0.5657 | 0.3833 | 0.6141 | 0.6344 | 0.6180 | 0.6449 | 0.4841 | 0.5387 | 0.4218 | 0.6221 | 0.5449 | 0.6572 | 1.0270 | 0.5584 | 0.3944 | 0.5138 | 0.5310 | 0.6533 | 1.3150 | 0.5147 | 0.6085 | 0.4804 | 0.6628 | 6.5488 | 0.5397 | 0.6574 | 0.4054 | 0.5050 | 0.6679 | 0.4130 |
Sedoheptulose 1-phosphate | 1.3458 | 1.3112 | 0.8151 | 1.0598 | 1.4033 | 1.4501 | 0.8370 | 0.8272 | 0.6698 | 0.3419 | 0.8467 | 0.8280 | 1.3069 | 0.8082 | 0.8040 | 0.9113 | 1.0029 | 0.8850 | 0.9946 | 1.1200 | 0.7509 | 0.7771 | 0.8994 | 0.9768 | 0.9283 | 0.8908 | 1.0328 | 0.4085 | 0.6092 | 0.8132 | 0.3901 |
sn-glycero-3-Phosphoethanolamine | 1.9804 | 1.8434 | 1.5667 | NA | 2.2663 | 1.0544 | NA | 0.2650 | 0.3174 | NA | 0.1246 | 0.3169 | NA | 0.2469 | 0.2423 | NA | 0.1681 | 0.2396 | 1.8682 | 0.7184 | NA | 0.0974 | 0.1642 | 1.5563 | 1.8920 | 0.2061 | 1.3977 | NA | 0.1274 | 0.1333 | NA |
sn-Glycerol 3-phosphate | 1.7585 | 1.4432 | 0.4302 | NA | 1.2082 | 2.8316 | 0.2705 | 0.0671 | 0.0262 | NA | 0.0930 | 0.1599 | NA | 0.0321 | 0.0241 | NA | 0.0944 | 0.1114 | 0.4189 | 0.5413 | 0.1084 | 0.1038 | 0.0274 | 1.4101 | 0.6113 | 0.0846 | 0.7808 | NA | 0.0672 | 0.0938 | NA |
Sphingosine 1-phosphate | 1.1006 | 1.1170 | 1.3382 | 2.2414 | 1.3536 | 1.4596 | 2.7955 | 1.0088 | 0.9062 | 1.0364 | 0.9215 | 0.9673 | 0.9350 | 0.9397 | 0.9018 | 1.1243 | 0.8940 | 0.7758 | 0.9592 | 0.9276 | 0.7043 | 0.8221 | 1.1183 | 0.9833 | 0.9120 | 0.9288 | 0.9106 | 0.5246 | 0.7941 | 0.9890 | 1.5022 |
Succinate | 5.3446 | 2.4595 | 1.4929 | 0.3304 | 1.5228 | 1.4115 | 0.6898 | 0.1884 | 0.1926 | 0.0931 | 0.4713 | 0.2790 | 0.2212 | 0.5034 | 0.2509 | 0.1044 | 0.2085 | 0.2553 | 0.5189 | 0.3277 | 0.4081 | 0.1998 | 0.2096 | 1.0797 | 0.8113 | 0.2581 | 0.9437 | 0.1092 | 0.1758 | 0.3267 | 0.0997 |
Sucrose | 2.4636 | 1.6812 | 0.2661 | NA | 2.8907 | 1.8207 | 0.1584 | 0.3090 | 0.3528 | NA | 0.6084 | 0.4703 | 0.1482 | 0.2346 | 0.4696 | 0.1617 | 0.2727 | 0.2900 | 1.4044 | 0.8385 | 0.2645 | 0.1368 | 0.1656 | 0.5237 | 1.6772 | 0.8604 | 1.0955 | 0.1798 | 0.2352 | 0.2120 | 0.1405 |
Tetradecanoic acid | 0.6558 | 0.6470 | 0.4625 | 0.2096 | 0.6243 | 0.6410 | 0.5285 | 0.4363 | 0.5189 | 0.2620 | 1.2430 | 0.9940 | 0.3179 | 0.6642 | 0.4181 | 0.3459 | 0.6766 | 0.8099 | 0.6822 | 2.4881 | 0.6758 | 0.6937 | 0.5390 | 0.9816 | 3.7475 | 0.8627 | 1.0353 | 0.8943 | 0.5306 | 0.4644 | 0.4024 |
Thymidine | 0.8628 | 0.6877 | 0.1776 | 0.1267 | 1.3735 | 1.1370 | 0.2028 | 0.9169 | 1.2237 | 0.1007 | 0.7845 | 0.9336 | 0.1186 | 0.4529 | 0.3906 | 0.1331 | 0.5282 | 0.6647 | 1.0859 | 1.3588 | 0.1804 | 0.9048 | 0.8206 | 1.0399 | 1.3642 | 1.1232 | 1.2335 | 0.1228 | 1.2623 | 1.7416 | 0.1180 |
UDP | 0.9517 | 0.9430 | 0.9569 | 0.6748 | 0.8627 | 0.8148 | 1.0985 | 0.9798 | 1.0707 | 0.5508 | 1.0818 | 1.0329 | 0.9357 | 1.1075 | 1.0497 | 0.8045 | 1.0103 | 1.0316 | 1.0553 | 1.0413 | 0.9698 | 1.0591 | 0.9149 | 1.0768 | 1.0204 | 0.9855 | 1.1172 | 0.7767 | 0.9466 | 0.9594 | 0.7750 |
Factors:
F1 | Sample source:Plasma | Time_Point:ED | Randomization:Control |
F2 | Sample source:Plasma | Time_Point:ED | Randomization:Experimental |
F3 | Sample source:Plasma | Time_Point:ED | Randomization:NA |
F4 | Sample source:Plasma | Time_Point:EMS | Randomization:Control |
F5 | Sample source:Plasma | Time_Point:Field | Randomization:Control |
F6 | Sample source:Plasma | Time_Point:Field | Randomization:Experimental |
F7 | Sample source:Plasma | Time_Point:Field | Randomization:NA |
F8 | Sample source:Plasma | Time_Point:Hour 120 | Randomization:Control |
F9 | Sample source:Plasma | Time_Point:Hour 120 | Randomization:Experimental |
F10 | Sample source:Plasma | Time_Point:Hour 120 | Randomization:NA |
F11 | Sample source:Plasma | Time_Point:Hour 12 | Randomization:Control |
F12 | Sample source:Plasma | Time_Point:Hour 12 | Randomization:Experimental |
F13 | Sample source:Plasma | Time_Point:Hour 12 | Randomization:NA |
F14 | Sample source:Plasma | Time_Point:Hour 168 | Randomization:Control |
F15 | Sample source:Plasma | Time_Point:Hour 168 | Randomization:Experimental |
F16 | Sample source:Plasma | Time_Point:Hour 168 | Randomization:NA |
F17 | Sample source:Plasma | Time_Point:Hour 24 | Randomization:Control |
F18 | Sample source:Plasma | Time_Point:Hour 24 | Randomization:Experimental |
F19 | Sample source:Plasma | Time_Point:Hour 2 | Randomization:Control |
F20 | Sample source:Plasma | Time_Point:Hour 2 | Randomization:Experimental |
F21 | Sample source:Plasma | Time_Point:Hour 2 | Randomization:NA |
F22 | Sample source:Plasma | Time_Point:Hour 48 | Randomization:Control |
F23 | Sample source:Plasma | Time_Point:Hour 48 | Randomization:Experimental |
F24 | Sample source:Plasma | Time_Point:Hour 4 | Randomization:Control |
F25 | Sample source:Plasma | Time_Point:Hour 4 | Randomization:Experimental |
F26 | Sample source:Plasma | Time_Point:Hour 6 | Randomization:Control |
F27 | Sample source:Plasma | Time_Point:Hour 6 | Randomization:Experimental |
F28 | Sample source:Plasma | Time_Point:Hour 6 | Randomization:NA |
F29 | Sample source:Plasma | Time_Point:Hour 72 | Randomization:Control |
F30 | Sample source:Plasma | Time_Point:Hour 72 | Randomization:Experimental |
F31 | Sample source:Plasma | Time_Point:Hour 72 | Randomization:NA |