Data for (Study ST003405)
(Analysis AN005589)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|
| 10-Hydroxydecanoate | 1.0334 | 0.9937 | 0.9927 | 1.0224 | 1.0167 | 1.0034 | 0.9950 | 0.9804 | 0.9869 | 0.9753 |
| 12-Hydroxydodecanoic acid | 1.0299 | 0.9872 | 0.9888 | 1.0168 | 0.9994 | 1.0080 | 0.9842 | 0.9945 | 1.0000 | 0.9913 |
| 2-Hydroxyglutarate | 1.0000 | 0.9845 | 0.9648 | 0.9808 | 0.9810 | 1.0311 | 1.0244 | 1.0042 | 1.0150 | 1.0143 |
| 2-Oxoglutarate | 1.0030 | 0.9888 | 0.9798 | 0.9947 | 0.9880 | 1.0283 | 1.0188 | 0.9840 | 1.0117 | 1.0029 |
| 3-Hydroxybutyric acid | 1.0136 | 0.9993 | 0.9812 | 1.0043 | 0.9974 | 1.0077 | 1.0099 | 0.9904 | 0.9978 | 0.9984 |
| 3-Hydroxyisobutyric acid | 1.0134 | 0.9999 | 0.9739 | 0.9930 | 0.9946 | 1.0099 | 1.0177 | 0.9865 | 1.0085 | 1.0026 |
| 3-Hydroxymethylglutarate | 1.0119 | 1.0031 | 1.0004 | 1.0027 | 1.0050 | 0.9936 | 0.9984 | 0.9857 | 0.9991 | 1.0000 |
| 3-Hydroxyphenylacetic acid | 1.0092 | 1.0312 | 1.0118 | 1.0316 | 1.0347 | 0.9649 | 0.9995 | 0.9718 | 0.9735 | 0.9717 |
| 3-Methylhistidine | 0.9983 | 0.9936 | 0.9739 | 1.0026 | 0.9883 | 1.0016 | 1.0032 | 1.0039 | 1.0194 | 1.0152 |
| 3-Phosphoglycerate | 1.0295 | 1.0038 | 0.9932 | 0.9993 | 1.0031 | 1.0032 | 0.9992 | 0.9771 | 0.9992 | 0.9923 |
| 3-Sulfinoalanine | 1.0114 | 1.0061 | 0.9901 | 1.0100 | 1.0143 | 0.9728 | 0.9902 | 0.9820 | 1.0068 | 1.0163 |
| 6-Phosphogluconic acid | 0.9840 | 0.9775 | 1.0117 | 0.9805 | 0.9844 | 0.9858 | 0.9954 | 1.0468 | 1.0249 | 1.0090 |
| Aconitate | 1.0400 | 1.0248 | 1.0011 | 0.9794 | 1.0161 | 1.0276 | 1.0149 | 0.9368 | 0.9635 | 0.9958 |
| Adenine | 1.0018 | 0.9966 | 0.9734 | 0.9978 | 0.9856 | 1.0086 | 1.0203 | 1.0040 | 1.0114 | 1.0006 |
| Adenosine diphosphate | 1.0144 | 0.9961 | 0.9943 | 1.0024 | 1.0011 | 1.0013 | 0.9938 | 0.9950 | 1.0031 | 0.9985 |
| Adenosine monophosphate | 1.0199 | 0.9876 | 0.9791 | 0.9904 | 0.9978 | 1.0036 | 0.9995 | 1.0123 | 1.0035 | 1.0064 |
| Adenosine phosphosulfate | 0.9965 | 1.0024 | 0.9445 | 0.9932 | 1.0205 | 1.0038 | 1.0103 | 0.9567 | 1.0372 | 1.0349 |
| Adenosine triphosphate | 1.0046 | 0.9933 | 1.0121 | 0.9993 | 0.9993 | 0.9870 | 0.9927 | 1.0124 | 1.0044 | 0.9949 |
| ADP-glucose | 1.0182 | 0.9901 | 0.9798 | 1.0016 | 0.9972 | 1.0168 | 1.0045 | 0.9893 | 1.0127 | 0.9899 |
| Alanine | 1.0042 | 0.9949 | 0.9885 | 0.9954 | 0.9948 | 1.0068 | 1.0034 | 0.9976 | 1.0071 | 1.0072 |
| Allantoin | 0.9905 | 0.9976 | 0.9625 | 1.0078 | 0.9973 | 1.0082 | 1.0141 | 0.9945 | 1.0163 | 1.0111 |
| Aminoadipic acid | 0.9713 | 0.9502 | 0.9268 | 0.9482 | 0.9488 | 1.0529 | 1.0493 | 1.0487 | 1.0534 | 1.0504 |
| Arginine | 1.0015 | 0.9953 | 0.9848 | 0.9993 | 0.9941 | 0.9920 | 1.0066 | 1.0084 | 1.0126 | 1.0054 |
| Ascorbate | 1.0269 | 1.0103 | 0.9888 | 1.0021 | 0.9997 | 1.0121 | 1.0057 | 0.9608 | 1.0035 | 0.9903 |
| Asparagine | 0.9776 | 0.9721 | 0.9741 | 0.9842 | 0.9818 | 1.0044 | 1.0090 | 1.0369 | 1.0268 | 1.0330 |
| Aspartic acid | 1.0139 | 1.0066 | 1.0031 | 1.0114 | 1.0105 | 0.9830 | 0.9888 | 0.9856 | 1.0002 | 0.9969 |
| Asp-glu | 1.0087 | 0.9957 | 0.9779 | 0.9982 | 0.9921 | 1.0050 | 1.0067 | 0.9962 | 1.0120 | 1.0075 |
| Azelaic acid | 1.0157 | 0.9949 | 0.9751 | 1.0048 | 0.9923 | 1.0249 | 0.9994 | 0.9977 | 1.0013 | 0.9940 |
| Benzoic acid | 0.9852 | 0.9886 | 1.0066 | 1.0043 | 0.9994 | 0.9924 | 1.0016 | 0.9927 | 1.0197 | 1.0095 |
| beta-Asp-Leu | 1.0245 | 0.9934 | 0.9584 | 1.0004 | 0.9792 | 1.0039 | 1.0190 | 0.9930 | 1.0190 | 1.0090 |
| Betaine | 0.9991 | 0.9886 | 0.9764 | 0.9903 | 0.9884 | 1.0071 | 1.0152 | 1.0020 | 1.0150 | 1.0179 |
| Butyric acid | 0.9974 | 1.0046 | 0.9945 | 1.0002 | 0.9952 | 1.0034 | 1.0022 | 1.0003 | 0.9991 | 1.0030 |
| Capric acid | 1.0155 | 0.9992 | 0.9864 | 1.0009 | 0.9993 | 1.0023 | 1.0023 | 0.9988 | 0.9992 | 0.9960 |
| Caprylic acid | 1.0017 | 1.0017 | 1.0056 | 0.9935 | 0.9821 | 0.9818 | 1.0298 | 1.0011 | 0.9932 | 1.0095 |
| Carnosine | 1.0085 | 1.0063 | 0.9870 | 1.0004 | 0.9920 | 0.9963 | 1.0099 | 0.9956 | 1.0054 | 0.9987 |
| CDP-ethanolamine | 0.9881 | 1.0052 | 1.0367 | 1.0060 | 1.0312 | 0.9409 | 0.9847 | 1.0132 | 0.9926 | 1.0015 |
| Cer(18:1;O2/16:0) | 0.9205 | 1.0421 | 1.0390 | 1.0455 | 0.9950 | 0.9720 | 0.9943 | 0.9848 | 1.0097 | 0.9971 |
| Citrate | 1.0338 | 1.0133 | 0.9999 | 0.9838 | 1.0113 | 1.0182 | 1.0125 | 0.9551 | 0.9768 | 0.9953 |
| Citrulline | 1.0103 | 0.9937 | 0.9722 | 0.9999 | 0.9889 | 0.9976 | 1.0004 | 1.0032 | 1.0179 | 1.0160 |
| Creatine | 1.0055 | 0.9969 | 0.9940 | 0.9972 | 0.9966 | 1.0088 | 1.0039 | 0.9920 | 1.0030 | 1.0022 |
| Creatinine | 1.0045 | 0.9997 | 0.9801 | 1.0026 | 0.9991 | 0.9965 | 1.0100 | 0.9911 | 1.0119 | 1.0044 |
| Cyclic AMP | 1.0060 | 0.9934 | 0.9706 | 0.9978 | 1.0333 | 1.0040 | 0.9723 | 0.9938 | 1.0103 | 1.0184 |
| Cys-gly | 1.0244 | 1.0120 | 0.9842 | 1.0082 | 1.0022 | 1.0107 | 1.0065 | 0.9783 | 0.9956 | 0.9780 |
| Cystathionine | 0.9183 | 0.9015 | 0.8770 | 0.9031 | 0.8950 | 1.0996 | 1.0988 | 1.0875 | 1.1073 | 1.1119 |
| Cysteic acid | 1.0357 | 0.9910 | 0.9446 | 0.9864 | 0.9862 | 1.0333 | 1.0085 | 0.9842 | 1.0148 | 1.0154 |
| Cystine | 1.0108 | 1.0162 | 0.9756 | 0.9787 | 0.9648 | 1.0024 | 0.9957 | 0.9840 | 1.0328 | 1.0391 |
| Cytidine diphosphate | 1.0080 | 0.9925 | 1.0017 | 0.9927 | 0.9989 | 0.9983 | 1.0006 | 1.0081 | 1.0035 | 0.9957 |
| Cytidine triphosphate | 0.9996 | 0.9947 | 1.0273 | 1.0025 | 1.0022 | 0.9768 | 0.9868 | 1.0135 | 1.0074 | 0.9891 |
| D4-DL-Lysine | 1.0293 | 0.9928 | 0.9884 | 0.9946 | 0.9983 | 0.9960 | 1.0001 | 0.9977 | 1.0058 | 0.9971 |
| d4-tyrosine | 1.0114 | 0.9975 | 0.9948 | 0.9999 | 0.9997 | 0.9980 | 1.0002 | 0.9987 | 1.0007 | 0.9991 |
| D5-Phenylalanine | 1.0105 | 0.9965 | 1.0004 | 0.9973 | 1.0023 | 0.9994 | 0.9961 | 0.9981 | 1.0003 | 0.9991 |
| Deaminoneuraminic acid | 1.0292 | 0.9992 | 0.9992 | 1.0033 | 1.0024 | 0.9904 | 0.9937 | 0.9770 | 1.0110 | 0.9947 |
| Deoxyguanosine monophosphate | 1.0238 | 0.9952 | 0.9965 | 0.9962 | 1.0007 | 0.9985 | 0.9906 | 0.9943 | 1.0065 | 0.9976 |
| Diacetyl | 1.0090 | 0.9947 | 1.0020 | 1.0016 | 0.9917 | 1.0070 | 0.9933 | 1.0043 | 0.9970 | 0.9994 |
| Dihydroorotate | 0.9906 | 0.9807 | 1.0107 | 1.0347 | 1.0022 | 0.9831 | 0.9822 | 0.9892 | 1.0246 | 1.0021 |
| Dihydroxyacetone phosphate | 0.9987 | 0.9920 | 0.9962 | 1.0034 | 0.9974 | 0.9857 | 0.9940 | 1.0148 | 1.0096 | 1.0083 |
| Docosahexaenoic acid | 1.0154 | 0.9905 | 1.0082 | 0.9928 | 0.9916 | 0.9891 | 1.0010 | 1.0075 | 1.0048 | 0.9992 |
| Dodecanoic acid | 1.0230 | 0.9936 | 0.9870 | 1.0048 | 0.9983 | 1.0040 | 0.9992 | 0.9983 | 0.9932 | 0.9986 |
| Erythrose 4-phosphate | 0.9704 | 0.9589 | 1.0367 | 0.9861 | 1.0067 | 0.9522 | 0.9779 | 1.0738 | 1.0252 | 1.0121 |
| FAD | 1.0088 | 0.9967 | 0.9805 | 1.0000 | 1.0082 | 1.0056 | 0.9869 | 1.0001 | 1.0037 | 1.0095 |
| Folic acid | 1.0029 | 1.0144 | 0.9855 | 0.9988 | 1.0017 | 0.9841 | 1.0128 | 0.9944 | 1.0035 | 1.0020 |
| Fructose-1,6-bisphosphate | 0.9937 | 0.9839 | 1.0295 | 1.0106 | 0.9998 | 0.9742 | 0.9723 | 1.0297 | 1.0075 | 0.9988 |
| Fructose 6-phosphate | 0.9767 | 0.9761 | 1.0222 | 0.9923 | 0.9987 | 0.9700 | 0.9868 | 1.0512 | 1.0148 | 1.0113 |
| Fumaric acid | 1.0115 | 0.9977 | 0.9855 | 1.0055 | 0.9996 | 1.0126 | 1.0090 | 0.9730 | 1.0068 | 0.9988 |
| Galactonic acid | 1.0207 | 1.0035 | 0.9681 | 1.0011 | 0.9992 | 1.0150 | 1.0132 | 0.9595 | 1.0170 | 1.0027 |
| Galacturonic acid | 0.9554 | 0.9759 | 0.9669 | 1.0169 | 0.9738 | 0.9980 | 1.0123 | 1.0205 | 1.0395 | 1.0408 |
| Gamma-glutamylalanine | 1.0132 | 0.9834 | 0.9511 | 0.9923 | 0.9845 | 1.0142 | 0.9999 | 0.9982 | 1.0287 | 1.0346 |
| Gamma-glutamylcysteine | 0.9819 | 0.9862 | 0.9657 | 0.9845 | 0.9763 | 0.9891 | 1.0066 | 1.0389 | 1.0287 | 1.0421 |
| GDP-glucose | 1.0117 | 1.0025 | 0.9964 | 0.9945 | 0.9994 | 1.0010 | 1.0011 | 0.9940 | 1.0004 | 0.9989 |
| Glucosamine | 1.0008 | 0.9899 | 0.9753 | 0.9898 | 0.9882 | 1.0097 | 1.0122 | 1.0006 | 1.0152 | 1.0184 |
| Glucosamine 6-phosphate | 1.0128 | 0.9954 | 0.9655 | 0.9867 | 0.9846 | 1.0167 | 1.0158 | 0.9954 | 1.0130 | 1.0142 |
| Glucose | 1.0102 | 1.0037 | 0.9899 | 1.0001 | 0.9993 | 0.9926 | 1.0087 | 0.9953 | 1.0030 | 0.9973 |
| Glucose 6-phosphate | 0.9791 | 0.9750 | 1.0267 | 0.9926 | 1.0016 | 0.9700 | 0.9808 | 1.0515 | 1.0117 | 1.0109 |
| Glu-glu | 1.0204 | 0.9935 | 0.9710 | 0.9998 | 0.9892 | 1.0126 | 1.0085 | 0.9898 | 1.0118 | 1.0034 |
| Glutamate | 1.0083 | 0.9953 | 0.9921 | 0.9994 | 0.9970 | 1.0031 | 1.0007 | 0.9980 | 1.0045 | 1.0014 |
| Glutamine | 0.9984 | 0.9977 | 0.9901 | 0.9975 | 0.9973 | 0.9896 | 0.9990 | 1.0085 | 1.0079 | 1.0141 |
| Glutathione | 1.0131 | 1.0028 | 0.9947 | 1.0033 | 1.0035 | 1.0022 | 1.0042 | 0.9882 | 0.9972 | 0.9908 |
| Gly-asp | 1.0151 | 0.9938 | 0.9716 | 0.9939 | 0.9886 | 1.0109 | 1.0023 | 0.9961 | 1.0159 | 1.0118 |
| Glyceraldehyde 3-p | 1.0353 | 0.9858 | 0.9697 | 0.9937 | 0.9825 | 1.0345 | 1.0039 | 0.9784 | 1.0127 | 1.0035 |
| Glyceric acid | 1.0065 | 0.9958 | 0.9977 | 1.0044 | 0.9991 | 1.0025 | 0.9946 | 0.9946 | 0.9996 | 1.0053 |
| Glycerol 3-phosphate | 0.9948 | 0.9936 | 1.0046 | 0.9973 | 1.0025 | 1.0021 | 0.9971 | 1.0041 | 0.9988 | 1.0052 |
| Glycine | 1.0040 | 0.9841 | 0.9643 | 0.9898 | 0.9856 | 1.0124 | 1.0084 | 1.0087 | 1.0209 | 1.0220 |
| Gly-glu | 1.0119 | 0.9918 | 0.9688 | 0.9942 | 0.9843 | 1.0065 | 1.0104 | 0.9998 | 1.0176 | 1.0149 |
| Gly-ser | 1.0044 | 0.9842 | 0.9629 | 0.9845 | 0.9833 | 1.0153 | 1.0099 | 1.0146 | 1.0208 | 1.0201 |
| Guanosine diphosphate | 1.0018 | 0.9984 | 1.0150 | 1.0030 | 1.0037 | 0.9858 | 0.9895 | 1.0031 | 1.0041 | 0.9955 |
| Guanosine triphosphate | 1.0027 | 0.9876 | 1.0303 | 1.0014 | 0.9974 | 0.9858 | 0.9909 | 1.0194 | 0.9969 | 0.9876 |
| Heptadecanoic acid | 1.0088 | 0.9974 | 0.9957 | 1.0156 | 0.9935 | 0.9996 | 0.9967 | 0.9959 | 1.0031 | 0.9936 |
| Heptanoic acid | 0.9155 | 1.0133 | 1.0080 | 1.0092 | 1.0076 | 1.0127 | 1.0047 | 1.0081 | 1.0081 | 1.0128 |
| Hippurate | 1.0006 | 1.0080 | 0.9812 | 1.0010 | 0.9953 | 0.9986 | 1.0158 | 0.9896 | 1.0096 | 1.0002 |
| Histidine | 1.0046 | 0.9963 | 0.8820 | 1.0034 | 0.9955 | 1.0084 | 1.0058 | 1.0294 | 1.0291 | 1.0454 |
| Hydroxyphenyllactic acid | 0.9847 | 0.9839 | 0.9784 | 0.9895 | 0.9832 | 1.0035 | 1.0147 | 1.0191 | 1.0201 | 1.0229 |
| Hypotaurine | 1.0179 | 1.0017 | 0.9864 | 0.9995 | 0.9983 | 1.0041 | 1.0181 | 0.9677 | 1.0069 | 0.9994 |
| Indolelactic acid | 1.0001 | 1.0018 | 0.9806 | 0.9917 | 0.9901 | 1.0002 | 1.0187 | 1.0003 | 1.0190 | 0.9975 |
| Inosine | 0.9640 | 1.0041 | 0.9994 | 1.0132 | 1.0043 | 0.9573 | 1.0110 | 1.0080 | 1.0161 | 1.0227 |
| Inosine-monophosphate | 1.0295 | 1.0060 | 0.9817 | 1.0093 | 1.0217 | 1.0017 | 1.0090 | 0.9424 | 1.0049 | 0.9938 |
| Isoleucine | 1.0035 | 0.9916 | 0.9836 | 0.9953 | 0.9928 | 0.9966 | 1.0040 | 1.0067 | 1.0123 | 1.0134 |
| Ketoleucine | 0.9901 | 0.9811 | 0.9711 | 0.9825 | 0.9804 | 1.0136 | 1.0219 | 1.0214 | 1.0200 | 1.0179 |
| Lactate | 1.0110 | 1.0034 | 0.9770 | 0.9981 | 0.9941 | 1.0099 | 1.0133 | 0.9845 | 1.0066 | 1.0019 |
| L-Arabitol | 1.0002 | 0.9932 | 0.9699 | 0.9975 | 0.9893 | 1.0068 | 1.0145 | 0.9960 | 1.0229 | 1.0096 |
| Leu-ala | 0.9867 | 0.9772 | 0.9633 | 0.9800 | 0.9646 | 1.0318 | 1.0168 | 1.0222 | 1.0316 | 1.0258 |
| Leucine | 1.0004 | 0.9925 | 0.9844 | 0.9963 | 0.9926 | 0.9964 | 1.0029 | 1.0083 | 1.0124 | 1.0140 |
| Linoleate | 1.0187 | 0.9860 | 0.9798 | 1.0146 | 0.9779 | 1.0148 | 1.0023 | 1.0098 | 0.9938 | 1.0023 |
| LPE(16:0/0:0) | 1.0236 | 1.0172 | 0.9813 | 1.0100 | 1.0054 | 0.9787 | 1.0000 | 0.9910 | 0.9950 | 0.9979 |
| LPE(18:0/0:0) | 0.9821 | 1.0207 | 0.9886 | 1.0064 | 1.0132 | 0.9735 | 1.0079 | 1.0008 | 0.9978 | 1.0090 |
| LPE(18:1) | 1.0307 | 1.0065 | 0.9726 | 1.0089 | 0.9960 | 0.9933 | 1.0068 | 0.9885 | 0.9974 | 0.9992 |
| Lysine | 1.0097 | 0.9936 | 0.9747 | 0.9982 | 0.9881 | 0.9925 | 1.0099 | 1.0070 | 1.0183 | 1.0079 |
| Malate | 1.0089 | 0.9994 | 0.9879 | 1.0042 | 0.9994 | 1.0105 | 1.0081 | 0.9772 | 1.0045 | 0.9998 |
| Maleic acid | 1.0179 | 1.0085 | 1.0057 | 1.0145 | 1.0140 | 0.9767 | 0.9845 | 0.9822 | 1.0008 | 0.9952 |
| Methionine | 0.9981 | 0.9900 | 0.9818 | 0.9959 | 0.9908 | 0.9969 | 1.0028 | 1.0116 | 1.0156 | 1.0165 |
| Myoinositol | 1.0171 | 1.0010 | 0.9843 | 1.0042 | 1.0048 | 1.0003 | 1.0047 | 0.9716 | 1.0070 | 1.0051 |
| Myristic acid | 1.0212 | 0.9893 | 0.9942 | 1.0054 | 0.9983 | 0.9981 | 0.9987 | 0.9959 | 0.9959 | 1.0030 |
| N-acetylaspartate | 1.0057 | 0.9943 | 0.9936 | 0.9919 | 0.9934 | 1.0067 | 1.0071 | 1.0000 | 1.0046 | 1.0028 |
| N-acetylasparthylglutamate | 0.9908 | 0.9819 | 0.9583 | 0.9779 | 0.9763 | 1.0223 | 1.0260 | 1.0157 | 1.0260 | 1.0245 |
| N-acetylcysteine | 0.9748 | 0.9827 | 0.9402 | 0.9802 | 0.9715 | 1.0098 | 1.0306 | 1.0180 | 1.0463 | 1.0459 |
| N-acetylglucosamine-6-phosphate | 0.9887 | 0.9610 | 1.0295 | 1.0156 | 1.0007 | 0.9787 | 0.9859 | 1.0261 | 1.0123 | 1.0015 |
| N-acetylglutamine | 0.9876 | 0.9783 | 0.9655 | 0.9739 | 0.9703 | 1.0262 | 1.0299 | 1.0193 | 1.0265 | 1.0226 |
| N-Acetylglutamine | 1.0072 | 0.9938 | 0.9698 | 0.9999 | 0.9884 | 1.0106 | 1.0094 | 0.9903 | 1.0164 | 1.0141 |
| N-acetylmethionine | 1.0058 | 0.9929 | 0.9492 | 0.9874 | 0.9719 | 1.0318 | 1.0224 | 0.9948 | 1.0232 | 1.0207 |
| N-acetylneuraminate | 1.0058 | 0.9954 | 0.9944 | 0.9984 | 0.9888 | 1.0012 | 1.0073 | 1.0007 | 1.0103 | 0.9976 |
| N-Acetylornithine | 0.9936 | 0.9875 | 0.9753 | 0.9974 | 0.9888 | 0.9999 | 1.0072 | 1.0132 | 1.0156 | 1.0215 |
| N-acetyltaurine | 1.0127 | 1.0007 | 0.9697 | 1.0068 | 0.9914 | 1.0158 | 1.0192 | 0.9651 | 1.0167 | 1.0019 |
| N-acetylvaline | 0.9995 | 1.0003 | 0.9672 | 1.0019 | 0.9827 | 1.0228 | 1.0148 | 0.9908 | 1.0090 | 1.0110 |
| NAD | 1.0005 | 0.9942 | 0.9985 | 0.9984 | 1.0019 | 1.0024 | 0.9971 | 1.0018 | 1.0039 | 1.0014 |
| NADH | 1.0028 | 0.9947 | 0.9789 | 0.9982 | 0.9951 | 1.0055 | 1.0083 | 0.9925 | 1.0177 | 1.0063 |
| NADP | 1.0040 | 0.9781 | 0.9946 | 0.9909 | 1.0082 | 1.0034 | 0.9992 | 1.0137 | 1.0066 | 1.0014 |
| N-formylmethionine | 0.9831 | 1.0060 | 0.9972 | 1.0011 | 0.9964 | 0.9919 | 1.0149 | 0.9978 | 1.0073 | 1.0043 |
| Nicotinamide | 0.9990 | 1.0136 | 0.9880 | 1.0034 | 0.9975 | 0.9880 | 1.0157 | 0.9934 | 1.0042 | 0.9972 |
| Oleic acid | 1.0167 | 0.9933 | 0.9917 | 1.0045 | 0.9843 | 1.0073 | 1.0030 | 1.0045 | 0.9956 | 0.9992 |
| Ophthalmic acid | 1.0108 | 0.9741 | 1.0031 | 1.0004 | 0.9869 | 0.9890 | 0.9758 | 1.0378 | 1.0067 | 1.0152 |
| Ornithine | 1.0051 | 0.9943 | 0.9802 | 1.0052 | 0.9975 | 0.9803 | 1.0035 | 1.0016 | 1.0201 | 1.0122 |
| Orotate | 0.9495 | 0.9538 | 1.0658 | 1.0425 | 0.9881 | 0.9441 | 0.9472 | 1.0730 | 1.0377 | 0.9983 |
| Oxalacetic acid | 1.0321 | 1.0268 | 1.0215 | 1.0203 | 1.0287 | 0.9754 | 0.9593 | 0.9859 | 0.9683 | 0.9818 |
| Oxalate | 1.0159 | 0.9990 | 1.0034 | 0.9998 | 0.9982 | 1.0006 | 0.9976 | 1.0066 | 0.9932 | 0.9858 |
| Oxidized glutathione | 1.0232 | 1.0081 | 1.0004 | 1.0113 | 1.0106 | 0.9900 | 0.9994 | 0.9813 | 0.9948 | 0.9809 |
| Palmitic acid | 1.0076 | 0.9909 | 0.9978 | 1.0085 | 1.0010 | 0.9974 | 0.9990 | 0.9978 | 0.9974 | 1.0025 |
| Palmitoleic acid | 1.0132 | 1.0104 | 0.9765 | 1.0035 | 0.9804 | 1.0102 | 1.0148 | 0.9961 | 0.9989 | 0.9960 |
| Pantothenic acid | 1.0127 | 1.0066 | 1.0152 | 1.0105 | 1.0090 | 0.9882 | 0.9899 | 0.9806 | 0.9965 | 0.9906 |
| PE(16:0/18:1) | 0.9081 | 1.0251 | 1.0187 | 1.0196 | 0.9972 | 0.9968 | 1.0158 | 0.9937 | 1.0165 | 1.0084 |
| PE(16:0/20:4) | 0.9247 | 1.0171 | 1.0088 | 1.0248 | 1.0316 | 0.9981 | 1.0006 | 0.9798 | 1.0111 | 1.0034 |
| Pelargonic acid | 1.0094 | 0.9981 | 0.9936 | 1.0038 | 0.9960 | 1.0010 | 0.9950 | 1.0033 | 0.9973 | 1.0025 |
| PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z)) | 0.8919 | 1.0070 | 1.0237 | 1.0069 | 0.9988 | 0.9923 | 1.0153 | 1.0233 | 1.0197 | 1.0210 |
| Phenylalanine | 0.9992 | 0.9896 | 0.9799 | 0.9938 | 0.9915 | 1.0003 | 1.0044 | 1.0099 | 1.0149 | 1.0164 |
| Phosphocreatine | 0.9987 | 0.9902 | 0.9890 | 0.9925 | 0.9924 | 0.9989 | 1.0115 | 1.0057 | 1.0116 | 1.0094 |
| Phosphoenolpyruvate | 1.0302 | 1.0080 | 0.9879 | 1.0026 | 1.0028 | 1.0094 | 1.0006 | 0.9751 | 0.9926 | 0.9908 |
| Phosphoethanolamine | 0.9719 | 0.9937 | 1.1193 | 0.9967 | 1.0351 | 0.9181 | 0.9557 | 1.0610 | 0.9610 | 0.9875 |
| Phosphorylcholine | 1.0072 | 1.0014 | 0.9834 | 0.9982 | 0.9961 | 1.0056 | 1.0086 | 0.9917 | 1.0057 | 1.0019 |
| Phosphoserine | 0.9287 | 0.9418 | 0.9955 | 0.9858 | 0.9777 | 0.9876 | 1.0107 | 1.0703 | 1.0508 | 1.0511 |
| Proline | 0.9972 | 0.9892 | 0.9798 | 0.9990 | 0.9949 | 1.0026 | 1.0083 | 0.9989 | 1.0157 | 1.0143 |
| Propenoic acid | 1.0078 | 1.0029 | 0.9899 | 1.0009 | 1.0019 | 0.9909 | 1.0088 | 0.9939 | 1.0053 | 0.9976 |
| Pseudouridine | 1.0035 | 1.0030 | 0.9907 | 1.0013 | 0.9992 | 0.9941 | 1.0074 | 0.9926 | 1.0099 | 0.9983 |
| Pyridoxine | 1.0066 | 1.0034 | 0.9833 | 1.0011 | 0.9955 | 0.9999 | 1.0100 | 0.9900 | 1.0098 | 1.0003 |
| Pyroglutamate | 1.0071 | 1.0033 | 0.9853 | 0.9982 | 0.9959 | 1.0007 | 1.0089 | 0.9925 | 1.0065 | 1.0015 |
| Pyruvate | 1.0154 | 1.0126 | 0.9916 | 1.0074 | 1.0052 | 0.9945 | 1.0041 | 0.9759 | 0.9991 | 0.9943 |
| Ribose-1-p | 0.9967 | 0.9889 | 0.9973 | 1.0054 | 1.0006 | 0.9821 | 0.9957 | 1.0221 | 1.0201 | 0.9911 |
| Ribulose 5-phosphate | 0.9820 | 0.9766 | 1.0038 | 1.0052 | 0.9926 | 0.9840 | 0.9864 | 1.0381 | 1.0243 | 1.0071 |
| Saccharopine | 0.9477 | 0.9099 | 0.9099 | 0.9383 | 0.9071 | 1.0767 | 1.0703 | 1.0911 | 1.0808 | 1.0681 |
| S-adenosylhomocysteine | 1.0219 | 1.0057 | 0.9868 | 0.9883 | 0.9983 | 1.0098 | 1.0033 | 0.9890 | 1.0028 | 0.9942 |
| Sedoheptulose-7-phosphate | 0.9729 | 0.9765 | 0.9972 | 0.9970 | 0.9892 | 0.9815 | 0.9967 | 1.0450 | 1.0306 | 1.0132 |
| Serine | 0.9982 | 0.9883 | 0.9819 | 0.9955 | 0.9912 | 0.9898 | 1.0017 | 1.0171 | 1.0153 | 1.0210 |
| Sorbitol | 1.0080 | 0.9983 | 1.0024 | 0.9949 | 0.9927 | 0.9990 | 1.0002 | 0.9997 | 1.0057 | 0.9990 |
| Stearic acid | 0.9872 | 0.9936 | 0.9999 | 1.0107 | 1.0016 | 0.9984 | 1.0027 | 1.0010 | 1.0006 | 1.0043 |
| Succinate | 1.0155 | 0.9882 | 0.9864 | 0.9948 | 1.0018 | 1.0158 | 1.0010 | 0.9911 | 0.9991 | 1.0063 |
| Succinic acid semialdehyde | 1.0092 | 1.0055 | 0.9899 | 1.0002 | 0.9991 | 0.9921 | 1.0089 | 0.9944 | 1.0036 | 0.9971 |
| Succinylacetone | 0.9738 | 0.9898 | 1.0015 | 1.0004 | 1.0119 | 0.9960 | 1.0017 | 1.0027 | 1.0099 | 1.0122 |
| Sucrose | 1.0216 | 0.9945 | 0.9867 | 0.9938 | 0.9977 | 1.0014 | 0.9984 | 0.9919 | 1.0134 | 1.0006 |
| Taurine | 1.0161 | 1.0039 | 0.9854 | 1.0034 | 1.0000 | 1.0068 | 1.0098 | 0.9708 | 1.0059 | 0.9979 |
| Thiamine | 1.0063 | 0.9998 | 0.9850 | 0.9963 | 0.9998 | 0.9956 | 1.0111 | 0.9956 | 1.0082 | 1.0023 |
| Threonine | 0.9955 | 0.9892 | 0.9789 | 0.9935 | 0.9918 | 0.9981 | 1.0032 | 1.0137 | 1.0160 | 1.0200 |
| Thymidine monophosphate | 1.0283 | 1.0258 | 0.9709 | 1.0093 | 1.0083 | 0.9958 | 1.0118 | 0.9621 | 0.9953 | 0.9925 |
| Thymine | 0.9830 | 1.0021 | 1.0151 | 1.0024 | 1.0060 | 0.9791 | 0.9906 | 1.0134 | 1.0054 | 1.0028 |
| Tryptophan | 0.9982 | 0.9886 | 0.9793 | 0.9943 | 0.9917 | 0.9991 | 1.0026 | 1.0126 | 1.0168 | 1.0167 |
| Tyrosine | 0.9974 | 0.9898 | 0.9799 | 0.9950 | 0.9911 | 0.9992 | 1.0055 | 1.0105 | 1.0155 | 1.0161 |
| UDP-glucose | 1.0103 | 0.9944 | 0.9952 | 1.0066 | 1.0072 | 0.9935 | 0.9970 | 0.9885 | 1.0077 | 0.9996 |
| UDP-glucuronic acid | 1.0034 | 0.9821 | 0.9946 | 0.9954 | 0.9883 | 1.0021 | 1.0010 | 1.0179 | 1.0117 | 1.0036 |
| UDP-n-acetylglucosamine | 1.0049 | 0.9868 | 0.9869 | 0.9962 | 0.9981 | 1.0044 | 1.0008 | 1.0042 | 1.0081 | 1.0095 |
| Uracil | 1.0122 | 1.0037 | 0.9940 | 0.9988 | 0.9988 | 0.9946 | 1.0085 | 0.9902 | 1.0035 | 0.9956 |
| Urate | 1.0083 | 1.0004 | 0.9799 | 0.9986 | 0.9927 | 1.0082 | 1.0085 | 0.9944 | 1.0078 | 1.0012 |
| Uridine diphosphate | 1.0163 | 0.9968 | 0.9957 | 0.9983 | 1.0070 | 1.0010 | 1.0029 | 0.9835 | 1.0060 | 0.9925 |
| Uridine monophosphate | 0.9996 | 0.9939 | 0.9937 | 1.0100 | 1.0057 | 0.9790 | 0.9967 | 1.0120 | 1.0131 | 0.9965 |
| Uridine triphosphate | 1.0003 | 1.0001 | 1.0206 | 1.0031 | 1.0063 | 0.9830 | 0.9963 | 0.9995 | 1.0006 | 0.9902 |
| Valine | 0.9979 | 0.9915 | 0.9829 | 0.9965 | 0.9922 | 0.9974 | 1.0042 | 1.0089 | 1.0130 | 1.0155 |
| Xanthine | 0.8860 | 1.0213 | 0.9921 | 1.0137 | 1.0102 | 1.0172 | 1.0283 | 0.9984 | 1.0218 | 1.0110 |
Factors:
| F1 | ATF4:KO | Treatment_time:0 |
| F2 | ATF4:KO | Treatment_time:0.5 |
| F3 | ATF4:KO | Treatment_time:24 |
| F4 | ATF4:KO | Treatment_time:4 |
| F5 | ATF4:KO | Treatment_time:8 |
| F6 | ATF4:WT | Treatment_time:0 |
| F7 | ATF4:WT | Treatment_time:0.5 |
| F8 | ATF4:WT | Treatment_time:24 |
| F9 | ATF4:WT | Treatment_time:4 |
| F10 | ATF4:WT | Treatment_time:8 |