Data for (Study ST003458)
(Analysis AN005682)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 |
|---|---|---|---|---|---|---|---|
| 1-{4-[(2R,3R)-3-(Hydroxymethyl)-4-isobutyl-5-oxo-2-morpholinyl]phenyl}-3-isopropylurea | 1.4310 | 1.1713 | 1.3222 | NA | 0.8432 | 0.4824 | 0.7739 |
| 2-(2-amino-3-methylbutanamido)-3-phenylpropanoic acid | 1.2522 | 1.1458 | 1.4059 | NA | 0.8890 | 0.5533 | 0.8069 |
| 2-Aminoadipic acid | 0.6321 | 1.0264 | 2.3572 | NA | 0.5346 | 0.9096 | 0.8393 |
| 2-C-Methyl-erythritol-4-phosphoric acid | 1.4454 | 0.6419 | 0.4442 | NA | 1.0935 | 1.0018 | 1.3124 |
| 2-Methylbutyrylglycine | 1.4761 | 1.1268 | 1.1259 | NA | 0.7105 | 0.4965 | 1.1278 |
| 2-Oxoglutaric acid | 0.6461 | 0.6946 | 0.6933 | NA | 1.4138 | 0.6723 | 2.0708 |
| 3-Indoxylsulfuric acid | 1.2370 | 0.2179 | 2.0601 | NA | 0.8859 | 1.1087 | 0.6739 |
| 3-Methyl-2-oxovaleric acid | 0.8929 | 1.1208 | 1.2975 | NA | 0.7669 | 0.6941 | 1.4029 |
| 4-{[(4,6-Dimethoxypyrimidin-2-yl)amino]methylidene}-2-phenyl-4,5-dihydro-1,3-oxazol-5-one | 0.6797 | 0.7361 | 1.0381 | NA | 1.5055 | 0.8934 | 1.2088 |
| 4,8-Dihydroxyquinoline-2-carboxylic acid | 2.9010 | 1.1554 | 0.7719 | NA | 0.6603 | 0.1669 | 0.0500 |
| 4-chloro-1H-indazol-3-amine | 1.6645 | 1.0712 | 1.8197 | NA | 0.4790 | 0.5244 | 0.5281 |
| 4-Hydroxybenzaldehyde | 0.8238 | 1.0217 | 0.9662 | NA | 1.0819 | 0.7139 | 1.5122 |
| 4-Methyl-2-oxovaleric acid | 0.9278 | 1.1246 | 1.3094 | NA | 0.7795 | 0.6962 | 1.3200 |
| 4-Phenolsulfonic acid | 1.7102 | 1.0648 | 1.3355 | NA | 0.0379 | 0.4794 | 1.6081 |
| 4-pyridoxic acid | 1.9823 | 1.3354 | 1.1081 | NA | 0.6843 | 0.3225 | 0.4593 |
| Allantoin | 1.7659 | 1.0114 | 1.3866 | NA | 0.6126 | 0.6263 | 0.5918 |
| Arginine | 1.2400 | 1.2329 | 1.4827 | NA | 0.6440 | 0.6991 | 0.7626 |
| cis-Aconitic acid | 1.2624 | 0.7615 | 1.0046 | NA | 1.0760 | 0.8385 | 1.0777 |
| Cysteine | 1.2196 | 0.6164 | 1.1574 | NA | 1.2382 | 0.9073 | 0.8674 |
| D-Alanyl-D-alanine | 1.2762 | 1.4671 | 1.5122 | NA | 0.5146 | 0.6184 | 0.6527 |
| Deoxyinosine | 2.1122 | 1.5587 | 1.3022 | NA | 0.2399 | 0.5152 | 0.1298 |
| Deoxyuridine | 1.9876 | 1.5846 | 1.3314 | NA | 0.2574 | 0.5274 | 0.1926 |
| Ethylmalonic acid/ Glutaric acid | 1.1441 | 1.2157 | 1.7859 | NA | 0.5918 | 0.5956 | 0.8178 |
| Fumaric acid | 1.1835 | 0.6885 | 0.8177 | NA | 1.1754 | 0.7885 | 1.4010 |
| Galactonic acid/ Gluconic acid | 0.9644 | 0.7406 | 1.0974 | NA | 1.1890 | 0.8002 | 1.3105 |
| Glucuronic acid | 1.0713 | 0.7100 | 0.7899 | NA | 1.2812 | 0.8641 | 1.3078 |
| Glyceric acid | 0.8230 | 0.9437 | 1.0330 | NA | 0.8761 | 0.7984 | 1.7121 |
| Glycylleucine | 1.2016 | 1.0873 | 1.4579 | NA | 0.6959 | 0.7331 | 0.9183 |
| Glyoxylic acid | 1.3297 | 0.5937 | 0.7709 | NA | 1.3125 | 0.7192 | 1.2890 |
| Hexanoylglycine | 1.6593 | 0.4031 | 1.0471 | NA | 1.1391 | 0.5626 | 1.2674 |
| Hexoses | 1.1031 | 0.8879 | 0.8488 | NA | 1.1168 | 0.9170 | 1.1181 |
| Hippuric acid | 0.8542 | 1.2497 | 1.3121 | NA | 1.0015 | 0.5966 | 1.0852 |
| Isocitric acid | 1.3456 | 0.7452 | 1.0322 | NA | 1.0661 | 0.7852 | 1.0450 |
| Itaconic acid | 2.6166 | 1.5469 | 1.0452 | NA | 0.2620 | 0.1955 | 0.1268 |
| Lactic acid | 0.7048 | 0.8366 | 0.7772 | NA | 1.3567 | 0.8841 | 1.5132 |
| L-Ascorbic acid 2-sulfate | 2.1805 | 1.8469 | 0.9373 | NA | 0.3671 | 0.2308 | 0.2290 |
| Malic acid | 1.2496 | 0.5429 | 0.7014 | NA | 1.4160 | 0.7073 | 1.4109 |
| N-Acetylmethionine | 1.4664 | 1.1873 | 1.5751 | NA | 0.6566 | 0.5589 | 0.5993 |
| N-Acetylneuraminic acid | 1.6655 | 1.3008 | 1.3224 | NA | 0.6684 | 0.4889 | 0.5129 |
| N-Acetylphenylalanine | 1.3825 | 1.2194 | 0.8837 | NA | 1.2462 | 0.4645 | 0.6994 |
| N-Isovalerylglycine | 2.1906 | 1.7203 | 0.8239 | NA | 0.4252 | 0.2904 | 0.3408 |
| Orotidine | 1.4875 | 0.8848 | 1.4612 | NA | 1.2052 | 0.2997 | 0.7027 |
| Pantothenic acid | 1.2748 | 1.1273 | 1.2174 | NA | 0.8685 | 0.6682 | 0.8643 |
| Pentoses | 0.7712 | 0.9252 | 1.0671 | NA | 1.1095 | 1.0508 | 1.1240 |
| Phenylacetylglycine | 2.1780 | 1.7426 | 0.4584 | NA | 0.2535 | 0.4254 | 0.7422 |
| Phosphoenolpyruvic acid | 1.3501 | 0.9961 | 1.2977 | NA | 0.7612 | 0.5405 | 1.1717 |
| Phosphoribosyl formamidocarboxamide | 1.2302 | 0.8746 | 1.1136 | NA | 0.8942 | 0.8020 | 1.1518 |
| Pimelic acid/ 3-Methyladipic acid | 1.0324 | 1.9958 | 0.7794 | NA | 0.6760 | 0.5510 | 0.8804 |
| Pyruvic acid | 0.6614 | 0.8126 | 0.9175 | NA | 1.1103 | 1.1107 | 1.4891 |
| Ribulose 5-phosphate | 1.9662 | 0.8033 | 0.8184 | NA | 0.9902 | 0.5167 | 0.8130 |
| Serine | 1.2136 | 1.1388 | 1.4192 | NA | 0.7597 | 0.6950 | 0.8382 |
| Succinic acid | 0.9228 | 0.9475 | 0.8689 | NA | 0.9618 | 1.0937 | 1.2301 |
| Sugar alcohol (C5) | 0.7310 | 0.7840 | 0.8740 | NA | 1.2147 | 1.1288 | 1.3146 |
| Sugar alcohol (C6) | 0.4945 | 1.0857 | 0.8565 | NA | 1.2796 | 1.0333 | 1.2860 |
| Taurine | 1.0020 | 1.0315 | 1.1213 | NA | 0.9619 | 0.9480 | 0.9541 |
| Theanine | 1.2670 | 1.2251 | 1.7127 | NA | 0.6134 | 0.6394 | 0.6272 |
| Threonic acid | 1.4134 | 0.6931 | 1.1334 | NA | 1.3077 | 0.5628 | 0.8973 |
| Thymidine | 1.8346 | 1.5419 | 1.1914 | NA | 0.3765 | 0.6626 | 0.2545 |
| Tolycaine | 0.9581 | 1.2431 | 1.1622 | NA | 0.9439 | 0.3990 | 1.4457 |
| Tyrosine | 1.2263 | 1.1913 | 1.4652 | NA | 0.6989 | 0.6842 | 0.8004 |
| UMP | 1.6717 | 0.9011 | 1.0341 | NA | 0.9836 | 0.6608 | 0.6763 |
| Uracil | 0.9969 | 0.9769 | 1.0795 | NA | 1.0240 | 0.9063 | 1.0483 |
| Uric acid | 0.9333 | 1.1505 | 1.2246 | NA | 0.9321 | 0.7855 | 1.0402 |
| Uridine | 2.0626 | 0.9031 | 0.9177 | NA | 0.8716 | 0.4932 | 0.6416 |
| VLH | 0.5563 | 1.3453 | 1.0531 | NA | 0.5926 | 0.3864 | 2.4393 |
| Xanthine | 0.9706 | 1.0208 | 1.1284 | NA | 0.9399 | 0.9048 | 1.0901 |
| Xanthosine | 1.4018 | 0.8155 | 0.8569 | NA | 1.0747 | 0.7095 | 1.1412 |
| α-aminobutyric acid/ N,N-Dimethylglycine | 1.0440 | 0.9838 | 1.1323 | NA | 1.0702 | 0.7950 | 1.0103 |
| α-Aspartylphenylalanine_1 | 1.3302 | 1.2037 | 1.4497 | NA | 0.8103 | 0.5259 | 0.7235 |
| α-Aspartylphenylalanine_2 | 1.0819 | 1.9955 | 1.2904 | NA | 0.5242 | 0.2520 | 0.9049 |
| δ-Gluconolactone | 1.0460 | 0.7344 | 0.9263 | NA | 1.1807 | 0.8402 | 1.3386 |
Factors:
| F1 | Sample source:Kidney | Group:CLP (24h) / 12C-Serin |
| F2 | Sample source:Kidney | Group:CLP (24h) / 13C-Serin |
| F3 | Sample source:Kidney | Group:CLP (24h) / Vehicle |
| F4 | Sample source:Kidney | Group:QC |
| F5 | Sample source:Kidney | Group:Sham / 12C-Serin |
| F6 | Sample source:Kidney | Group:Sham / 13C-Serin |
| F7 | Sample source:Kidney | Group:Sham / Vehicle |
