Data for (Study ST003461)
(Analysis AN005688)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 |
|---|---|---|---|---|---|---|---|
| 2/3-Hydroxybutyric acid | 1.9309 | 0.6238 | 1.6619 | NA | 0.1742 | 1.0488 | 0.6345 |
| 2-Aminoadipic acid | 0.9981 | 1.5099 | 1.7760 | NA | 0.4962 | 0.8333 | 0.4408 |
| 2-C-Methyl-erythritol-4-phosphoric acid | 1.1128 | 1.1717 | 1.0291 | NA | 0.7581 | 1.0013 | 0.9123 |
| 2^-Deoxycytidine 5^-monophosphate (dCMP) | 0.8248 | 0.9059 | 0.9531 | NA | 0.9612 | 1.4723 | 0.8278 |
| 2-Oxoglutaric acid | 1.2269 | 0.9975 | 1.0467 | NA | 0.8884 | 0.8155 | 1.0489 |
| 4-Methyl-2-oxovaleric acid | 0.6301 | 1.2734 | 0.9362 | NA | 0.6435 | 1.4114 | 1.1193 |
| 6-Chloro-5-methyl-1H-1,2,3-benzotriazole | 1.2639 | 1.0368 | 0.8852 | NA | 1.0000 | 0.8671 | 0.8911 |
| 7-hydroxy-3-phenyl-4H-chromen-4-one | 1.0533 | 1.3629 | 1.0248 | NA | 0.9347 | 0.7333 | 0.8629 |
| 7-Methylguanosine | 0.7974 | 0.9644 | 1.1519 | NA | 0.9413 | 1.2278 | 0.9403 |
| Adenosine | 0.9481 | 0.8782 | 0.9235 | NA | 1.2098 | 1.0631 | 0.9442 |
| Alanyltyrosine | 1.0224 | 1.2093 | 1.0510 | NA | 0.9069 | 0.9498 | 0.8312 |
| Allantoin | 2.1983 | 1.2159 | 0.7717 | NA | 0.5481 | 0.5498 | 0.5455 |
| Asparagine | 0.7808 | 1.1462 | 1.0829 | NA | 1.1535 | 0.9610 | 0.8618 |
| Aspartame_1 | 0.9605 | 1.2344 | 1.1521 | NA | 0.7625 | 1.0677 | 0.8145 |
| Aspartame_2 | 0.8714 | 1.3638 | 0.9786 | NA | 0.9176 | 0.9022 | 0.9480 |
| Aspartic acid | 0.7516 | 1.1364 | 1.0943 | NA | 1.1617 | 0.9740 | 0.8741 |
| cis-Aconitic acid | 1.1396 | 1.0286 | 1.0424 | NA | 0.9389 | 0.8744 | 0.9821 |
| Deoxycytidine | 0.8939 | 1.0383 | 1.0290 | NA | 0.8383 | 1.4050 | 0.7369 |
| Deoxyinosine | 0.8976 | 0.9231 | 0.9581 | NA | 0.9521 | 1.3922 | 0.8217 |
| Deoxyuridine | 1.2940 | 1.2321 | 0.9687 | NA | 0.6790 | 1.1092 | 0.6122 |
| Ethylmalonic acid/ Glutaric acid | 1.0526 | 1.3828 | 1.2772 | NA | 0.5906 | 0.7070 | 1.0787 |
| Fumaric acid | 1.0535 | 1.0375 | 1.1160 | NA | 1.0716 | 0.8396 | 0.8810 |
| Galactonic acid/ Gluconic acid | 1.1133 | 1.2004 | 1.1927 | NA | 0.9007 | 0.8165 | 0.7660 |
| Glucose-6-phosphate | 0.9152 | 1.2380 | 1.1019 | NA | 0.9174 | 0.9846 | 0.8244 |
| Glucuronic acid | 1.0745 | 1.2748 | 1.1704 | NA | 0.7522 | 0.8855 | 0.8471 |
| Glutamic acid/ N-Methylaspartic acid | 0.8691 | 1.0638 | 1.0292 | NA | 1.0870 | 0.9978 | 0.9473 |
| Glutamine | 0.9775 | 1.1336 | 1.0990 | NA | 0.8781 | 1.0982 | 0.7844 |
| Glutathione | 1.1541 | 1.0581 | 0.7120 | NA | 1.2915 | 0.6722 | 1.0534 |
| Glyceric acid | 0.5757 | 1.0453 | 0.8087 | NA | 1.3706 | 1.1573 | 0.9928 |
| Glycine | 0.9046 | 1.0802 | 1.1634 | NA | 0.9267 | 1.1668 | 0.7321 |
| Glycylleucine | 0.9123 | 1.1700 | 1.1000 | NA | 1.0166 | 0.9657 | 0.8139 |
| Glycylvaline | 1.0053 | 1.0069 | 1.0788 | NA | 0.9799 | 1.1193 | 0.7726 |
| Guanosine | 0.9401 | 0.8841 | 1.0230 | NA | 1.1340 | 1.0022 | 1.0298 |
| Hexoses | 0.9517 | 1.0582 | 1.1297 | NA | 0.9154 | 1.1453 | 0.7761 |
| Isocitric acid | 1.1129 | 1.0611 | 1.0312 | NA | 0.9362 | 0.8873 | 0.9722 |
| Isophthalic acid | 0.9152 | 1.1431 | 0.8950 | NA | 1.0561 | 0.9522 | 1.0163 |
| Itaconic acid | 2.3957 | 1.4087 | 1.7350 | NA | 0.1171 | 0.1995 | 0.1036 |
| Lactic acid | 0.6020 | 0.9916 | 0.9879 | NA | 1.2871 | 0.8457 | 1.3770 |
| Leucylalanine | 0.9190 | 1.3812 | 1.2612 | NA | 0.7951 | 0.9366 | 0.6963 |
| Malic acid | 1.0091 | 1.0584 | 1.1269 | NA | 1.0069 | 0.9491 | 0.8417 |
| Mucic acid | 0.9961 | 0.9970 | 1.1381 | NA | 1.1194 | 0.9945 | 0.7193 |
| N-Acetylalanine | 1.0889 | 1.0823 | 1.0378 | NA | 0.8167 | 1.1601 | 0.7648 |
| N-Acetylaspartic acid | 1.1458 | 0.8141 | 0.8773 | NA | 1.2071 | 1.0005 | 0.8995 |
| N-Acetyl-D-galactosamine 4-sulfate_1 | 1.0394 | 1.1244 | 1.1079 | NA | 0.8071 | 0.8481 | 1.1334 |
| N-Acetyl-D-galactosamine 4-sulfate_2 | 1.0996 | 1.0890 | 1.0957 | NA | 0.8529 | 0.8859 | 1.0011 |
| N-Acetylmethionine | 1.0480 | 1.1308 | 0.9962 | NA | 0.9863 | 0.9371 | 0.8675 |
| N-Acetylneuraminic acid | 1.2290 | 1.1283 | 0.9740 | NA | 0.8070 | 0.9524 | 0.8703 |
| Orotidine | 1.0828 | 1.0383 | 0.9810 | NA | 1.2152 | 0.7897 | 0.8511 |
| Oxidized glutathione | 0.8186 | 1.2812 | 1.1834 | NA | 1.1546 | 0.7533 | 0.8062 |
| Pantothenic acid | 0.8879 | 1.5541 | 1.0871 | NA | 0.7736 | 0.8752 | 0.7917 |
| Pentoses | 1.0775 | 1.0502 | 0.9691 | NA | 0.9879 | 0.9075 | 1.0001 |
| Pyruvic acid | 0.8237 | 1.4329 | 1.1384 | NA | 0.9400 | 0.8242 | 0.8338 |
| Ribulose 5-phosphate | 0.9747 | 1.1863 | 0.8977 | NA | 0.8789 | 0.7424 | 1.3926 |
| Succinic acid | 1.0019 | 1.0992 | 0.8903 | NA | 0.8498 | 0.7204 | 1.5481 |
| Sugar alcohol (C5) | 0.9175 | 0.8447 | 0.7579 | NA | 1.5169 | 0.8343 | 1.0908 |
| Sugar alcohol (C6) | 1.1268 | 0.9734 | 0.7737 | NA | 1.0771 | 0.8775 | 1.1531 |
| Taurine | 1.0392 | 0.9788 | 0.9987 | NA | 1.0439 | 0.9481 | 0.9880 |
| Theanine | 1.0120 | 1.0219 | 1.0477 | NA | 1.0718 | 1.0078 | 0.8011 |
| Threonic acid | 1.3032 | 1.1060 | 1.0572 | NA | 0.8237 | 0.9171 | 0.7428 |
| Threonine/ Homoserine | 0.8786 | 1.1830 | 1.1844 | NA | 0.8358 | 1.1499 | 0.7526 |
| Thymidine | 0.9461 | 1.0981 | 1.0889 | NA | 0.9159 | 1.0243 | 0.9319 |
| Thymidine 5^-monophosphate | 0.7566 | 1.0999 | 0.9796 | NA | 0.8649 | 1.2962 | 0.9969 |
| Tyrosine | 0.9064 | 1.0364 | 1.1903 | NA | 1.0188 | 1.1297 | 0.6881 |
| Tyrosylalanine | 1.6445 | 0.8166 | 0.5596 | NA | 0.9526 | 0.8696 | 1.0626 |
| UMP | 1.4124 | 1.0938 | 0.8073 | NA | 1.1315 | 0.6672 | 0.7860 |
| Uracil | 0.9507 | 1.3513 | 1.4080 | NA | 0.6288 | 1.0111 | 0.6696 |
| Uric acid | 0.7137 | 1.3160 | 1.4872 | NA | 0.7879 | 0.8412 | 0.9677 |
| Uridine | 1.1427 | 0.9920 | 0.9401 | NA | 1.0171 | 0.9235 | 0.9596 |
| Uridine 5^-diphosphogalactose | 1.2187 | 1.1202 | 0.7634 | NA | 1.1429 | 0.6704 | 1.0338 |
| VLH | 0.8512 | 1.2684 | 1.1924 | NA | 1.1248 | 0.7601 | 0.8016 |
| Xanthine | 0.8668 | 1.1764 | 1.1542 | NA | 0.8955 | 1.0534 | 0.8563 |
| Xanthosine | 1.3518 | 1.1686 | 0.6537 | NA | 1.0907 | 0.4483 | 1.2670 |
| α-aminobutyric acid/ N,N-Dimethylglycine | 0.8663 | 1.0071 | 1.0738 | NA | 1.1353 | 1.0119 | 0.8986 |
Factors:
| F1 | Sample source:Spleen | Group:CLP (24h) / 12C-Serin |
| F2 | Sample source:Spleen | Group:CLP (24h) / 13C-Serin |
| F3 | Sample source:Spleen | Group:CLP (24h) / Vehicle |
| F4 | Sample source:Spleen | Group:QC |
| F5 | Sample source:Spleen | Group:Sham / 12C-Serin |
| F6 | Sample source:Spleen | Group:Sham / 13C-Serin |
| F7 | Sample source:Spleen | Group:Sham / Vehicle |
