Data for (Study ST003485)
(Analysis AN005723)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 |
---|---|---|---|---|---|---|---|
3-Methyldioxyindole | 1.4791 | 1.3988 | 2.5281 | 0.3938 | 0.2638 | 0.4534 | 0.4829 |
3-Methyleneoxindole | 1.1174 | 1.0864 | 2.3724 | 0.6215 | 0.7134 | 0.5231 | 0.5659 |
5-Hydroxyindoleacetate | 1.0104 | 0.8786 | 1.3732 | 0.6702 | 0.7587 | 0.7864 | 1.5224 |
5-hydroxytryptophan | 1.9664 | 0.8128 | 1.2451 | 0.6662 | 0.9172 | 0.6361 | 0.7562 |
Anthranilate | 1.5701 | 0.4248 | 4.2360 | 0.1526 | 0.1448 | 0.2675 | 0.2042 |
Indole | 1.1146 | 1.0893 | 2.3386 | 0.6088 | 0.7364 | 0.5320 | 0.5801 |
Indole-3-acetaldehyde | 1.2216 | 1.0492 | 2.3730 | 0.6134 | 0.7020 | 0.5004 | 0.5405 |
Indole-3-acetate | 2.7177 | 0.5997 | 1.1813 | 1.2205 | 0.4055 | 0.4145 | 0.4607 |
Indoxyl | 1.8011 | 2.0939 | 2.7714 | 0.0761 | 0.1031 | 0.0731 | 0.0813 |
kynurenine | 1.0488 | 0.9191 | 1.4379 | 0.6444 | 0.7455 | 0.6912 | 1.5131 |
L-tryptophan | 1.0691 | 1.1247 | 2.4208 | 0.6069 | 0.7089 | 0.5094 | 0.5602 |
N-formyl kynurenine | 1.3620 | 1.1372 | 1.8622 | 0.7088 | 0.4578 | 0.5754 | 0.8966 |
Picolinic acid | 5.3802 | 0.6557 | 0.2976 | 0.1430 | 0.2122 | 0.1715 | 0.1398 |
Factors:
F1 | cell line:BT549 | TDO2 status:sh negative control | Treatment:none | Sample source:culture media |
F2 | cell line:BT549 | TDO2 status:shTDO2-82 | Treatment:none | Sample source:culture media |
F3 | cell line:BT549 | TDO2 status:shTDO2-98 | Treatment:none | Sample source:culture media |
F4 | cell line:SUM159PT | TDO2 status:empty vector | Treatment:vehicle | Sample source:culture media |
F5 | cell line:SUM159PT | TDO2 status:overexpression | Treatment:10 uM AT0174 | Sample source:culture media |
F6 | cell line:SUM159PT | TDO2 status:overexpression | Treatment:1 uM AT0174 | Sample source:culture media |
F7 | cell line:SUM159PT | TDO2 status:overexpression | Treatment:vehicle | Sample source:culture media |