Data for (Study ST003488)
(Analysis AN005726)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|
| 3-Methyleneoxindole | 1.5722 | 1.1359 | 1.1406 | 1.0376 | 0.4635 | 0.8935 | 1.2316 | 0.9208 | 1.1490 | 0.4553 |
| 5-Hydroxyindoleacetate | 1.8455 | 1.0185 | 0.8713 | 1.1005 | 0.2425 | 1.1775 | 0.7431 | 0.7972 | 1.6225 | 0.5814 |
| 8-Methoxykynurenate | 0.5442 | 0.3347 | 0.3416 | 0.3681 | 0.3084 | 1.2300 | 2.9561 | 1.8993 | 1.8431 | 0.1745 |
| Anthranilate | 1.8668 | 1.3271 | 1.2225 | 1.1373 | 0.9424 | 0.0910 | 1.9122 | 0.0492 | 0.4626 | 0.9889 |
| g-Oxalo-crotonate | 2.9843 | 1.9732 | 2.5575 | 1.9386 | 0.0033 | 0.0476 | 0.0872 | 0.2557 | 0.1489 | 0.0037 |
| Hydroxyindole-acetylglycine | 1.6887 | 0.8282 | 1.1393 | 1.0898 | 0.5322 | 0.8516 | 1.8416 | 0.8838 | 0.8397 | 0.3049 |
| Indole | 1.5816 | 1.0883 | 1.1524 | 1.0611 | 0.4677 | 0.8855 | 1.2625 | 0.9241 | 1.1463 | 0.4306 |
| Indole-3-acetaldehyde | 1.7459 | 1.8921 | 1.4996 | 1.3502 | 0.0436 | 1.4506 | 0.4269 | 0.4257 | 1.1118 | 0.0535 |
| Indole-3-acetate | 1.6333 | 1.6875 | 1.1878 | 1.3713 | 0.1436 | 1.3775 | 0.6569 | 0.7094 | 1.0532 | 0.1797 |
| Indolepyruvate | 1.3039 | 1.1078 | 1.0850 | 1.0308 | 0.6122 | 0.8468 | 1.1935 | 1.0263 | 1.1646 | 0.6291 |
| Indoxyl | 1.4498 | 1.2268 | 1.2868 | 1.0559 | 0.3585 | 0.9033 | 0.9979 | 1.0826 | 1.1578 | 0.4806 |
| kynurenine | 1.7190 | 1.0056 | 0.8866 | 1.1215 | 0.2479 | 1.1764 | 0.7426 | 0.8051 | 1.7056 | 0.5896 |
| L-tryptophan | 1.5415 | 1.2506 | 1.0972 | 1.0178 | 0.4173 | 0.8735 | 1.3687 | 0.9372 | 1.0743 | 0.4219 |
| N-formyl kynurenine | 1.6629 | 0.8381 | 0.9924 | 1.5023 | 0.1286 | 1.0755 | 0.6918 | 0.5206 | 2.0537 | 0.5340 |
| Picolinic acid | 1.8804 | 1.1803 | 0.8862 | 1.0748 | 0.0125 | 1.3997 | 0.1788 | 0.8937 | 2.4793 | 0.0145 |
Factors:
| F1 | treatment:10uM 680c91 | Sample source:culture media |
| F2 | treatment:10uM AT0174 | Sample source:culture media |
| F3 | treatment:10uM Epacadotstat | Sample source:culture media |
| F4 | treatment:DMSO | Sample source:culture media |
| F5 | treatment:EV | Sample source:culture media |
| F6 | treatment:shSCR | Sample source:culture media |
| F7 | treatment:shTDO2-054 | Sample source:culture media |
| F8 | treatment:shTDO2-082 | Sample source:culture media |
| F9 | treatment:shTDO2-098 | Sample source:culture media |
| F10 | treatment:TDO2 OE | Sample source:culture media |
