Data for (Study ST003501)
(Analysis AN005749)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 |
|---|---|---|---|---|---|---|
| 13C3-Citric acid | NA | NA | NA | NA | NA | NA |
| 13C4-Fumaric acid | NA | NA | NA | NA | NA | NA |
| 13C4-Malic acid | NA | NA | NA | NA | NA | NA |
| 13C4-Succinic acid | 0.9989 | 0.9996 | 1.0001 | 1.0044 | 0.9982 | 1.0007 |
| 13C5-Oxoglutaric acid | 0.9953 | 1.0024 | 0.9980 | 1.0016 | 0.9991 | 1.0027 |
| 13C6-Benzoic acid | 0.9967 | 1.0016 | 0.9984 | 1.0005 | 0.9997 | 1.0021 |
| 13C8-Octanic acid | 0.9969 | 1.0004 | 0.9987 | 0.9995 | 1.0002 | 1.0022 |
| 15N5-ADP | 1.0118 | 0.9977 | 1.0138 | 1.0482 | 0.9751 | 0.9910 |
| 2-Hydroxyglutarate | NA | NA | NA | NA | NA | NA |
| 2-Phosphoglyceric acid | NA | NA | NA | NA | NA | NA |
| 3-Hydroxybutyric acid | NA | NA | NA | NA | NA | NA |
| 3-Phosphoglyceric acid | NA | NA | NA | NA | NA | NA |
| 6-Phosphogluconic acid | NA | NA | NA | NA | NA | NA |
| Acetoacetic acid | NA | NA | NA | NA | NA | NA |
| Adenosine monophosphate | NA | NA | NA | NA | NA | NA |
| Adenosine triphosphate | NA | NA | NA | NA | NA | NA |
| Adenosine triphosphate-d4 | NA | NA | NA | NA | NA | NA |
| ADP | NA | NA | NA | NA | NA | NA |
| Alanine | NA | NA | NA | NA | NA | NA |
| Alanine-d4 | 0.9860 | 1.0037 | 0.9964 | 0.9967 | 1.0035 | 1.0059 |
| Arginine | NA | NA | NA | NA | NA | NA |
| Arginine-d4C13 | 0.9951 | 1.0011 | 0.9998 | 0.9991 | 0.9999 | 1.0028 |
| Asparagine | NA | NA | NA | NA | NA | NA |
| Aspartic acid | NA | NA | NA | NA | NA | NA |
| Aspartic acid-d3 | 0.9958 | 1.0010 | 0.9996 | 1.0007 | 0.9991 | 1.0026 |
| cis-Aconitic acid | NA | NA | NA | NA | NA | NA |
| Dihydroxyacetone phosphate | NA | NA | NA | NA | NA | NA |
| Erythose 4-phosphate | NA | NA | NA | NA | NA | NA |
| Fructose 1,6-bisphosphate | 1.0109 | 0.9894 | 1.0114 | 1.0235 | 0.9965 | 0.9867 |
| Fructose 1-phosphate | NA | NA | NA | NA | NA | NA |
| Fructose 6-phosphate | NA | NA | NA | NA | NA | NA |
| Fumaric acid | NA | NA | NA | NA | NA | NA |
| Glucose 1-phosphate | NA | NA | NA | NA | NA | NA |
| Glucose 6-phosphate | 0.9995 | 0.9898 | 1.0078 | 1.0260 | 0.9902 | 1.0003 |
| Glutamic acid | NA | NA | NA | NA | NA | NA |
| Glutamic acid-d3 | 0.9952 | 1.0003 | 0.9989 | 1.0011 | 0.9998 | 1.0029 |
| Glutamine | NA | NA | NA | NA | NA | NA |
| Glyceraldehyde 3-phosphate | NA | NA | NA | NA | NA | NA |
| Lactic acid | 0.9819 | 0.9493 | 1.0023 | 1.0501 | 0.9898 | 1.0267 |
| Malic acid | NA | NA | NA | NA | NA | NA |
| NAD | NA | NA | NA | NA | NA | NA |
| NADH | NA | NA | NA | NA | NA | NA |
| NADP | NA | NA | NA | NA | NA | NA |
| NADPH | NA | NA | NA | NA | NA | NA |
| Oxalacetic acid | NA | NA | NA | NA | NA | NA |
| Oxoglutaric acid | NA | NA | NA | NA | NA | NA |
| Phosphocreatine | 1.0191 | 1.0029 | 1.0350 | 1.0128 | 0.9555 | 1.0064 |
| Phosphoenolpyruvic acid | NA | NA | NA | NA | NA | NA |
| Pyruvic acid | NA | NA | NA | NA | NA | NA |
| Ribose 5-phosphate | NA | NA | NA | NA | NA | NA |
| Ribulose 5-phosphate | NA | NA | NA | NA | NA | NA |
| Sedoheptulose 7-phosphate | 1.0232 | 0.9911 | 1.0184 | 1.0239 | 0.9686 | 1.0025 |
| Serine | NA | NA | NA | NA | NA | NA |
| Succinic acid | 0.9979 | 0.9962 | 0.9991 | 0.9958 | 0.9986 | 1.0070 |
| Sum of Citric acid and Isocitric acid | NA | NA | NA | NA | NA | NA |
| U-13C10,U-15N5-Adenosine monophosphate | NA | NA | NA | NA | NA | NA |
| U-13C3-Pyruvic acid | 0.9923 | 1.0066 | 0.9959 | 0.9939 | 0.9980 | 1.0076 |
| U-13C6-Glucose 6-phosphate | 1.0102 | 0.9983 | 1.0019 | 1.0100 | 1.0041 | 0.9857 |
| Xylulose 5-phosphate | NA | NA | NA | NA | NA | NA |
Factors:
| F1 | genotype:APP | condition:high | group:high_disease |
| F2 | genotype:APP | condition:low | group:low_disease |
| F3 | genotype:APP | condition:mid | group:mid_disease |
| F4 | genotype:NA | condition:NA | group:NA |
| F5 | genotype:WT | condition:low | group:low_healthy |
| F6 | genotype:WT | condition:mid | group:mid_healthy |
