Data for (Study ST003516)
(Analysis AN005773)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| 6-Phosphogluconic_acid_(area_norm) | 2.1268 | 0.0714 | NA | NA | 0.0635 | NA | NA | 0.0168 |
| Adenosine_5-diphosphate | 0.9968 | 0.8824 | NA | 0.6043 | 1.0242 | 0.6542 | 1.0274 | 1.8106 |
| Adenosine_5-triphosphate | 0.8669 | 2.0918 | NA | 0.2052 | 1.1456 | 0.2722 | 0.4464 | 1.9720 |
| alpha-Ketoglutaric_acid | 0.6333 | 1.3457 | NA | 0.5654 | 0.8595 | 0.5767 | 0.9273 | 2.0921 |
| Citric_acid | 1.4424 | 0.2969 | NA | 0.7002 | 1.4025 | 0.7009 | 1.2632 | 1.1939 |
| "D-Fructose_1,6-biphosphate_(area_norm)" | 1.3283 | 2.0414 | NA | 0.3704 | 0.6626 | 0.4411 | 0.6066 | 1.5496 |
| DL-Glyceraldehyde_3-phosphate_(area_norm) | 1.0883 | 0.6843 | NA | 0.7964 | 1.0152 | 0.9424 | 1.0904 | 1.3829 |
| Erytrose-4-phosphate_(area_norm) | 2.1856 | 0.2195 | NA | 0.7996 | 1.3490 | 0.9669 | 0.9944 | 0.4851 |
| Fructose_6-phosphate | 1.3991 | 0.6942 | NA | 0.5212 | 1.5099 | 0.5077 | 0.6803 | 1.6876 |
| Glucose_6-phosphate | 2.6255 | 0.2310 | NA | 0.4985 | 1.8973 | 0.4105 | 0.6123 | 0.7248 |
| Glutathione_Reduced | 1.2100 | 0.3032 | NA | 0.9624 | 1.2434 | 0.9140 | 1.2461 | 1.1209 |
| Itaconic_acid | 0.9819 | 0.0838 | NA | 1.4624 | 0.7305 | 0.8569 | 2.4848 | 0.3996 |
| Lactic_acid | 1.0675 | 1.1458 | NA | 0.8692 | 0.5616 | 0.6575 | 0.8450 | 1.8534 |
| L-Malic_acid | 0.8802 | 1.8133 | NA | 0.8178 | 0.7259 | 0.5919 | 0.9433 | 1.2275 |
| NAD | 1.1336 | 0.5882 | NA | 0.7797 | 1.0880 | 0.8821 | 1.1053 | 1.4230 |
| NADH | 1.3503 | 1.4924 | NA | 0.5685 | 0.6041 | 1.4924 | 0.9594 | 0.5330 |
| NADP | 0.7158 | 0.7661 | NA | 0.8629 | 0.9775 | 0.8180 | 1.1262 | 1.7334 |
| Pyruvic_acid | 0.6594 | 2.3435 | NA | 0.5439 | 0.5767 | 0.7710 | 0.7065 | 1.3990 |
| Ribose/Ribulose_5-phosphate | 2.8198 | 0.0802 | NA | 0.5322 | 1.1146 | 0.5505 | 0.6906 | 1.2121 |
| Sedoheptulose_7-phosphate | 1.8620 | 0.3311 | NA | 0.8569 | 1.2030 | 1.0305 | 1.0312 | 0.6853 |
| Succinic_acid | 0.8645 | 0.5253 | NA | 1.1199 | 1.0394 | 0.6771 | 1.5480 | 1.2258 |
| Xylulose/Ribose/Ribulose_5-phosphate | 1.6629 | 0.3006 | NA | 1.1296 | 1.6541 | 0.6184 | 0.8703 | 0.7640 |
Factors:
| F1 | Sample source:J774A.1_murine_macrophages | Experimental_Group:6-aminonicotinamide | Treatment:6-aminonicotinamide_11µM_for_24hrs | Genotype:wildtype |
| F2 | Sample source:J774A.1_murine_macrophages | Experimental_Group:6-phosphogluconate_dehydrogenase_knockdown | Treatment:- | Genotype:sh6PGD2 |
| F3 | Sample source:J774A.1_murine_macrophages | Experimental_Group:Calibration_Curve | Treatment:- | Genotype:ISTD+SAMPLE_MIX |
| F4 | Sample source:J774A.1_murine_macrophages | Experimental_Group:Control | Treatment:- | Genotype:wildtype |
| F5 | Sample source:J774A.1_murine_macrophages | Experimental_Group:empty_vector_control | Treatment:- | Genotype:MLP |
| F6 | Sample source:J774A.1_murine_macrophages | Experimental_Group:Oxythiamine | Treatment:Oxythiamine_520µM_for_24hrs | Genotype:wildtype |
| F7 | Sample source:J774A.1_murine_macrophages | Experimental_Group:Physcion | Treatment:Physcion_9µM_for_24hrs | Genotype:wildtype |
| F8 | Sample source:J774A.1_murine_macrophages | Experimental_Group:Transketolase_knockdown | Treatment:- | Genotype:shTKT2 |
