Data for (Study ST003519)

(Analysis AN005777)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3
1-pyrroline-2-carboxylate 1.0879 1.0767 0.8098
2-3-diphosphoglycerate 2.1227 0.4195 0.6514
2-aminomuconate 1.3756 1.0077 0.6141
2-deoxyguanosine-5-diphosphate-(dGDP) 1.3361 0.9298 0.7575
2-deoxyguanosine-5-monophosphate-(dGMP) 1.4788 0.5286 1.1497
2-deoxyguanosine-5-triphosphate-(dGTP) 1.3590 0.7663 0.9526
2-deoxythymidine-5-monophosphate-(dTMP) 1.3664 1.1545 0.4276
2-hydroxyadipate 1.0225 1.1030 0.8402
2-hydroxybutyrate 1.2044 1.1762 0.5607
2-hydroxyglutarate-(2-HG) 1.3234 1.1215 0.5147
2-methylglutarate 1.3939 1.3703 0.1124
2-oxoglutarate-(a-KG) 1.4205 0.9614 0.6310
2-phosphoglycerate 1.3156 0.7302 1.0441
2-propylglutarate 1.2374 1.0343 0.7169
3-hydroxybutyrate 1.5195 0.6764 0.9120
3-hydroxymethylglutarate 1.0225 1.1030 0.8402
4-hydroxyglutamate-semialdehyde 1.2266 1.0334 0.7288
5-phosphoribosyl-N-formylglycinamide 2.7281 0.0637 0.5203
acetylcarnitine 1.4878 1.0528 0.4418
adenosine-3-phosphate-5-phosphosulfate 1.3528 0.6574 1.1040
adenosine-5-diphosphate-(ADP) 1.3361 0.9298 0.7575
adenosine-5-monophosphate-(AMP) 1.4788 0.5286 1.1497
adenosine-5-triphosphate-(ATP) 1.3590 0.7663 0.9526
adenylsuccinate 1.5760 0.9310 0.5160
ADP-glucose 2.0407 0.3657 0.8051
ADP-ribose 1.9970 0.2630 0.9856
aspartate-(Asp) 1.0887 1.2962 0.5164
aspartylglutamate-(Asp-Glu) 1.0887 1.3534 0.4401
butyrate 1.0552 1.2570 0.6022
CDP-ethanolamine 1.3895 0.2339 1.6320
cis-aconitate 1.0816 1.2486 0.5870
citrate 1.1402 1.1664 0.6379
citryl-glutamate 0.9436 1.1938 0.7980
CMP-N-acetylneuraminate 1.3062 1.1224 0.5307
cyclic-AMP-(cAMP) 1.8776 0.6415 0.6004
cysteate 1.3979 1.0619 0.5196
cytidine-5-diphosphate-(CDP) 1.4881 0.3030 1.4413
cytidine-5-monophosphate-(CMP) 1.2852 0.3918 1.5258
cytidine-5-triphosphate-(CTP) 1.8817 0.4229 0.8877
deoxyribose-5-phosphate 0.3918 1.9439 0.3497
erythrose-4-phosphate 0.3443 1.2343 1.3434
flavin-adenine-dinucleotide-(FAD) 1.5889 0.8603 0.5975
flavin-mononucleotide-(FMN) 1.1834 1.1519 0.6141
fructose-1-6-bisphosphate 0.6290 0.3703 2.2106
fructose-1-phosphate 0.8905 0.5315 1.7342
fructose-6-phosphate 0.2103 1.2940 1.3977
fumarate 1.0563 0.0192 2.2515
galactarate 1.2675 1.1025 0.5959
galactose-1-phosphate 1.3996 1.0681 0.5096
galacturonate 0.8707 1.5757 0.3616
gamma-glutamylalanine-(g-Glu-Ala) 1.1952 1.1784 0.5669
gamma-glutamyltaurine 1.4324 1.1512 0.3660
GDP-mannose 1.8126 0.2951 1.1272
glucarate 1.5615 0.6118 0.9562
gluconate 1.1472 0.9901 0.8659
gluconate-6-phosphate 0.2258 0.5950 2.3142
glucono-1-5-lactone 1.2425 1.1541 0.5520
glucose 1.0108 1.2530 0.6518
glucose-1-6-bisphosphate 0.6236 0.3670 2.2204
glucose-1-phosphate 0.8486 0.8083 1.4071
glucose-6-phosphate 0.2075 1.2847 1.4129
glucuronate-1-phosphate 1.1084 0.9517 0.9560
glutamate-(Glu) 1.2373 1.0540 0.6907
glutamylglutamate-(Glu-Glu) 1.2444 1.2295 0.4497
glutarate 1.4877 0.7361 0.8641
glutathione--reduced-(GSH) 1.1615 0.8811 0.9970
glycerate 0.8974 1.4883 0.4516
glycerol-3-phosphate 1.1426 0.5554 1.4502
glycerophosphocholine 1.1085 1.3779 0.3875
glyoxylate 1.2905 1.0503 0.6425
guanosine-5-diphosphate-(GDP) 1.3911 0.8589 0.7970
guanosine-5-monophosphate-(GMP) 1.3138 0.7366 1.0374
guanosine-5-triphosphate-(GTP) 1.4883 0.5453 1.1179
homocysteinesulfinate 1.0602 1.5423 0.2167
hydroxypropanedioate 1.2993 1.0794 0.5948
inosine-5-monophosphate-(IMP) 1.8705 0.3151 1.0427
isocitrate 1.1473 1.0819 0.7435
ketoleucine 0.9740 1.0294 0.9867
lactate 1.0838 0.9964 0.9210
malate 1.2815 1.0225 0.6885
maleate 1.1785 0.0571 2.0787
malonate 1.1602 0.9709 0.8786
mannose-6-phosphate 0.3946 1.2186 1.3139
N-acetylaspartate 1.3461 1.0030 0.6499
N-acetylglutamate 0.9682 1.3088 0.6201
N-acetylmethionine 1.1306 0.9896 0.8834
N-acetylneuraminate 0.9928 1.2041 0.7350
N-formylmethionine 1.4476 1.0393 0.5000
O-phosphoethanolamine 1.2764 0.3081 1.6461
orotate 1.5252 0.7828 0.7644
orotidine 1.1847 1.2185 0.5240
oxalate 1.4152 0.8026 0.8480
oxaloacetate-(OAA) 1.0794 1.2127 0.6370
pantothenate 1.1386 0.9031 0.9906
phosphocreatine 2.4269 0.1885 0.6552
phosphoenolpyruvate 1.5401 0.5381 1.0758
pyridoxal-5-phosphate-(P5P) 1.5233 0.8758 0.6422
pyroglutamate-(pGlu) 0.9060 1.4370 0.5113
pyruvate 1.1341 1.0554 0.7920
riboflavin-cyclic-4-5-phosphate 1.4699 0.8660 0.7088
ribonate 1.5830 0.5958 0.9560
ribose-1-5-bisphosphate 1.0592 1.2750 0.5742
ribose-1-phosphate 0.9438 1.2166 0.7673
sedoheptulose-1-7-bisphosphate 1.4642 0.6917 0.9468
sedoheptulose-7-phosphate 1.4743 0.8539 0.7205
succinate 1.1536 0.9612 0.8982
succinate-semialdehyde 1.0810 1.0281 0.8815
taurine 1.1749 0.9818 0.8494
threonate 0.8790 1.4652 0.5007
thymidine-5-monophosphate-(TMP) 1.3664 1.1545 0.4276
UDP-N-acetylgalactosamine-(UDP-GalNAc) 1.8178 0.3926 0.9921
UDP-N-acetylglucosamine-(UDP-GlcNAc) 1.8058 0.2254 1.2270
urate 1.2126 1.2087 0.5092
ureidosuccinate 0.8734 0.0767 2.3576
uridine 0.8676 1.2772 0.7628
uridine-5-diphosphate-(UDP) 1.4201 0.4796 1.2737
uridine-5-monophosphate-(UMP) 1.2483 0.2699 1.7251
uridine-5-triphosphate-(UTP) 1.5408 0.5667 1.0370
xansthosine-5-monophosphate-(XMP) 1.3857 0.9496 0.6815
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Factors:

F1Treatment:"Ischemia for 25 mins, followed by reperfusion for 30 mins"
F2Treatment:Non-ischemia control
F3Treatment:Preperfusion of insluin for 30 mins before ischemia and reperfusion
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