Data for (Study ST003525)
(Analysis AN005789)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 |
|---|---|---|---|
| 10-Formyldihydrofolate | 2.0198 | 0.4979 | 0.6513 |
| 2^,3^-Cyclic CMP | 1.2155 | 1.0560 | 0.7145 |
| 3-Methyldioxyindole | 1.0780 | 1.1270 | 0.7895 |
| 5-10-Methenyltetrahydrofolate | 0.8746 | 1.3030 | 0.7747 |
| 5-Hydroxyisourate | 1.6428 | 0.9045 | 0.5348 |
| (5-L-Glutamyl)-L-glutamine | 1.6409 | 0.8131 | 0.6380 |
| 5-Oxoproline | 1.4836 | 0.8811 | 0.7022 |
| 5-Phosphoribosylamine | 0.8694 | 1.3824 | 0.6912 |
| 6-Hydroxykynurenic acid | 1.4493 | 0.4869 | 0.8179 |
| 6-Phospho-D-gluconate | 1.4975 | 0.9102 | 0.6576 |
| Acetylcholine | 1.1994 | 1.2453 | 0.5503 |
| acyl-C18:2 (Linoleoyl-CoA) | 1.1067 | 1.3782 | 0.4850 |
| acyl-C18:2-OH | 1.4509 | 0.8503 | 0.7655 |
| acyl-C20:4 | 1.0797 | 1.1959 | 0.7115 |
| acyl-C4-DC | 1.3601 | 0.7893 | 0.9141 |
| acyl-C4-OH (Hydroxybutyrylcarnitine) | 0.8372 | 1.0873 | 1.0478 |
| acyl-C5:1 (Tiglylcarnitine) | 0.8572 | 1.0399 | 1.0826 |
| acyl-C5-OH (hydroxyisovalerylcarnitine) | 1.0406 | 1.1029 | 0.8496 |
| acyl-C6-DC | 1.1999 | 1.1138 | 0.6959 |
| Adenine | 0.9414 | 1.1636 | 0.8703 |
| Adenosine | 1.1692 | 1.3171 | 0.4972 |
| Adenylosuccinic acid | 0.6773 | 0.5451 | 1.7923 |
| Allantoate | 0.9889 | 0.8935 | 1.1283 |
| AMP | 0.7861 | 1.1346 | 1.0406 |
| Anthranilate | 0.8033 | 1.2558 | 0.8907 |
| Biliverdin | 1.8958 | 0.8246 | 0.0979 |
| butanoyl-l-carnitine (acyl-C4) | 0.5878 | 1.4847 | 0.8278 |
| Carnosine | 1.8363 | 0.5992 | 0.7020 |
| CDP | 0.7956 | 1.6590 | 0.4494 |
| CDP-choline | 1.2209 | 0.9718 | 0.8350 |
| Choline | 1.2859 | 0.9705 | 0.7786 |
| Creatine | 1.2210 | 1.0914 | 0.7020 |
| Creatinine | 1.0471 | 1.0784 | 0.8711 |
| Cys-Gly | 1.2609 | 0.9394 | 0.8354 |
| Cytosine | 2.4251 | 0.5921 | 0.1865 |
| D-4--Phosphopantothenate | 1.0212 | 0.7916 | 1.2127 |
| dAMP | 0.9477 | 1.0086 | 1.0369 |
| D-Glucosamine | 1.1432 | 0.5967 | 1.3207 |
| Dimethylglycine | 1.3754 | 1.1333 | 0.5182 |
| Dopamine | 1.0914 | 1.1473 | 0.7551 |
| Ectoine | 1.2340 | 0.9876 | 0.8058 |
| Flavin mononucleotide | 1.0945 | 1.1033 | 0.8013 |
| Formyl-5-hydroxy-kynurenamine | 1.8797 | 0.7466 | 0.4996 |
| gamma-Glutamyl-gamma-aminobutyrate | 1.7243 | 0.7944 | 0.5846 |
| gamma-Glutamyl-Se-methylselenocysteine | 0.8171 | 0.8523 | 1.3267 |
| gamma-L-Glutamyl-D-alanine | 1.5579 | 0.8226 | 0.7012 |
| gamma-L-Glutamyl-L-cysteine | 1.4065 | 1.0756 | 0.5546 |
| gamma-L-Glutamylputrescine | 1.6288 | 0.6793 | 0.7974 |
| Glutathione | 1.2655 | 0.9189 | 0.8541 |
| glycine | 1.2913 | 1.0079 | 0.7322 |
| g-Oxalo-crotonate | 0.7334 | 0.7805 | 1.4808 |
| Guanidinoacetate | 2.1631 | 0.7784 | 0.2124 |
| Guanine | 1.1095 | 1.1765 | 0.7065 |
| Guanosine | 1.1156 | 1.1548 | 0.7253 |
| Hexadecenoyl-carnitine (acyl-C16:1) | 0.7002 | 1.5883 | 0.6128 |
| hexanoyl-L-carnitine (acyl-C6) | 0.7368 | 1.5909 | 0.5774 |
| Hypotaurine | 1.0088 | 1.3958 | 0.5524 |
| Hypoxanthine | 1.1118 | 0.8323 | 1.0870 |
| Indole | 0.9377 | 0.9503 | 1.1989 |
| Indole-3-acetaldehyde | 1.3373 | 1.0005 | 0.6996 |
| Indole-3-acetate | 1.3210 | 1.0380 | 0.6724 |
| Indolepyruvate | 0.6620 | 0.8816 | 1.4320 |
| Indoxyl | 0.5835 | 0.8101 | 1.5812 |
| Inosine | 1.1228 | 0.8194 | 1.0915 |
| kynurenine | 1.8797 | 0.7466 | 0.4996 |
| L-Adrenaline | 0.7014 | 0.8822 | 1.3963 |
| L-alanine | 1.0012 | 1.2014 | 0.7752 |
| L-arginine | 1.5853 | 0.6915 | 0.8225 |
| L-asparagine | 1.2796 | 1.0060 | 0.7448 |
| L-Carnitine | 1.0593 | 1.0012 | 0.9459 |
| L-Citrulline | 1.0448 | 0.8650 | 1.1102 |
| L-cysteine | 1.5379 | 0.8810 | 0.6541 |
| L-glutamate | 1.1971 | 1.0847 | 0.7307 |
| L-glutamine | 1.5503 | 0.8512 | 0.6761 |
| L-histidine | 1.1979 | 0.9644 | 0.8636 |
| L-leucine | 1.3823 | 0.9104 | 0.7598 |
| L-lysine | 1.0723 | 1.0952 | 0.8300 |
| L-methionine | 1.5090 | 0.7557 | 0.8190 |
| L-octanoylcarnitine (acyl-C8) | 0.7798 | 1.5057 | 0.6339 |
| L-Palmitoylcarnitine (acyl-C16) | 1.1286 | 1.5699 | 0.2524 |
| L-phenylalanine | 1.4703 | 0.7826 | 0.8235 |
| L-proline | 1.2911 | 1.0526 | 0.6827 |
| L-serine | 1.2299 | 0.8520 | 0.9601 |
| L-threonine | 1.4348 | 0.8853 | 0.7409 |
| L-tryptophan | 1.1906 | 0.9636 | 0.8710 |
| L-tyrosine | 1.3822 | 0.8686 | 0.8063 |
| L-valine | 1.3819 | 0.9399 | 0.7272 |
| N-Acetyl-L-citrulline | 1.6720 | 0.6494 | 0.7922 |
| N-Acetylornithine | 1.7987 | 0.5904 | 0.7451 |
| NAD+ | 0.8620 | 1.2458 | 0.8495 |
| NADP+ | 0.8570 | 0.9902 | 1.1380 |
| N-formyl kynurenine | 2.1390 | 0.3404 | 0.7205 |
| Nicotinamide | 1.1466 | 0.8548 | 1.0310 |
| N-Methylethanolamine phosphate | 1.5747 | 0.8919 | 0.6093 |
| Octadecanoyl-L-carnitine (acyl-C18) | 1.2395 | 1.4259 | 0.3138 |
| octenoyl-l-carnitine (acyl-C8:1) | 0.9392 | 1.3542 | 0.6605 |
| O-Decenoyl-L-carnitine (acyl-C10:1) | 0.6958 | 1.2035 | 1.0443 |
| O-dodecanoyl-carnitine (acyl-C12) | 0.8258 | 1.6683 | 0.4123 |
| O-dodecenoyl-carnitine (acyl-C12:1) | 1.1948 | 1.0903 | 0.7265 |
| O-octadecenoyl-L-carnitine (acyl-C18:1) | 0.8590 | 1.5065 | 0.5626 |
| Ornithine | 1.2125 | 0.9424 | 0.8751 |
| O-tetradecanoyl-L-carnitine (acyl-C14) | 1.0514 | 1.5395 | 0.3549 |
| Pantetheine | 1.5104 | 0.8886 | 0.6701 |
| Pantetheine 4--phosphate | 0.4777 | 0.7132 | 1.7829 |
| Phosphocreatine | 0.7288 | 1.1908 | 1.0413 |
| Phosphoserine | 1.1376 | 1.2346 | 0.6170 |
| Picolinic acid | 0.8066 | 1.0816 | 1.0812 |
| propionyl-carnitine (acyl-C3) | 1.0354 | 1.1897 | 0.7578 |
| Putrescine | 1.2637 | 1.2421 | 0.4966 |
| Pyridoxal | 1.0775 | 1.1457 | 0.7692 |
| Pyridoxamine 5^-phosphate | 0.9080 | 1.0752 | 0.9982 |
| (R)-S-Lactoylglutathione | 0.9019 | 0.9974 | 1.0901 |
| S-Adenosyl-L-homocysteine | 1.0856 | 0.9342 | 0.9970 |
| S-Adenosyl-L-methionine | 1.0989 | 1.0200 | 0.8899 |
| Serotonin | 1.5690 | 0.9919 | 0.5032 |
| S-Glutathionyl-L-cysteine | 0.9598 | 1.1392 | 0.8810 |
| Spermidine | 1.0244 | 1.3360 | 0.6049 |
| Spermine | 0.1689 | 2.4804 | 0.0938 |
| Sphingosine | 1.3571 | 1.0365 | 0.6420 |
| Tetradecenoyl Carnitine (acyl-C14:1) | 0.9835 | 1.5129 | 0.4447 |
| Thymine | 1.2743 | 1.0113 | 0.7436 |
Factors:
| F1 | Genotype:Aged Berk |
| F2 | Genotype:Aged B-Thals |
| F3 | Genotype:WT (b-thal negative) |
