Data for (Study ST003526)

(Analysis AN005791)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3
10-Formyldihydrofolate 0.6181 1.5502 0.7629
2^,3^-Cyclic CMP 1.1283 0.9639 0.7541
3-Methyldioxyindole 0.8313 0.9520 1.1979
5-10-Methenyltetrahydrofolate 0.7140 1.5780 0.6762
5-Hydroxyisourate 1.0865 0.9799 0.9433
(5-L-Glutamyl)-L-glutamine 1.0550 1.2258 0.7253
5-Oxoproline 0.9817 0.9877 1.0285
5-Phosphoribosylamine 0.6784 0.4175 1.8036
6-Hydroxykynurenic acid 0.5692 1.3120 1.0709
6-Phospho-D-gluconate 0.7064 0.8372 1.4238
8-Methoxykynurenate 1.7866 1.0799 0.2209
Acetylcholine 1.2643 1.1194 0.6456
acyl-C18:2 (Linoleoyl-CoA) 1.5305 0.8799 0.6486
acyl-C18:2-OH 1.2395 1.0572 0.7299
acyl-C20:4 0.7451 0.8154 1.4111
acyl-C4-DC 1.3442 1.1290 0.5650
acyl-C4-OH (Hydroxybutyrylcarnitine) 0.9009 1.2326 0.8555
acyl-C5:1 (Tiglylcarnitine) 0.6984 1.0151 1.2530
acyl-C5-OH (hydroxyisovalerylcarnitine) 0.9107 1.0955 0.9839
acyl-C6-DC 1.1179 0.9389 0.9563
Adenine 0.9931 1.0855 0.9206
Adenosine 0.6821 1.1394 1.1432
Adenylosuccinic acid 1.1572 1.0607 0.7995
Allantoate 1.1493 1.2038 0.6635
AMP 0.9243 0.9634 1.1039
Anthranilate 0.9756 1.4091 0.6126
Biliverdin 1.5755 0.7211 0.7673
butanoyl-l-carnitine (acyl-C4) 1.0552 1.0429 0.9080
Carnosine 1.3916 0.8959 0.7560
CDP 1.0993 1.1505 0.7613
CDP-choline 0.8658 1.0114 1.1079
Choline 1.0333 0.9851 0.9853
Creatine 0.7334 0.9319 1.3051
Creatinine 0.8905 0.8958 1.2015
Cys-Gly 1.2665 1.0143 0.7488
Cytosine 1.1005 0.6566 1.2541
D-4--Phosphopantothenate 1.2765 1.2283 0.5259
dAMP 1.5385 0.9313 0.5901
Dimethylglycine 0.5134 0.7657 1.6668
Dopamine 0.7097 1.2399 1.0181
Ectoine 0.9425 0.8832 1.1679
Flavin mononucleotide 1.1661 0.9051 0.9472
gamma-Glutamyl-gamma-aminobutyrate 1.2026 1.2909 0.5290
gamma-Glutamyl-Se-methylselenocysteine 0.8325 1.2411 0.9078
gamma-L-Glutamyl-D-alanine 1.1090 1.1496 0.7535
gamma-L-Glutamyl-L-cysteine 1.6044 1.1051 0.3576
gamma-L-Glutamylputrescine 1.0575 1.4643 0.4846
Glutathione 1.2781 0.9991 0.7537
glycine 1.2126 1.1110 0.7000
g-Oxalo-crotonate 0.4890 0.7929 1.6613
Guanidinoacetate 1.2780 0.9701 0.7828
Guanine 0.7231 1.2757 0.9705
Guanosine 0.5227 1.3349 1.0894
Hexadecenoyl-carnitine (acyl-C16:1) 1.4695 0.9078 0.6749
hexanoyl-L-carnitine (acyl-C6) 1.2968 0.9969 0.7393
Hypotaurine 0.6892 0.7616 1.5147
Hypoxanthine 0.6951 1.2146 1.0564
Indole 0.8437 0.9633 1.1757
Indole-3-acetaldehyde 0.3807 0.5863 1.9642
Indole-3-acetate 0.6852 0.8627 1.4171
Indolepyruvate 0.8981 1.1051 0.9855
Indoxyl 0.6157 1.1083 1.2333
Inosine 0.5286 1.4608 0.9582
L-Adrenaline 0.8793 0.9454 1.1619
L-alanine 0.9717 1.1542 0.8709
L-arginine 1.1071 1.0477 0.8571
L-asparagine 1.1352 1.1268 0.7530
L-Carnitine 0.9562 1.0013 1.0376
L-Citrulline 1.2044 0.9921 0.8261
L-cysteine 0.8417 0.9173 1.2234
L-glutamate 0.9723 1.0081 1.0165
L-glutamine 0.9602 0.9559 1.0794
L-histidine 0.9064 1.0347 1.0484
L-leucine 0.8962 1.1065 0.9858
L-lysine 1.0645 1.1775 0.7651
L-methionine 0.9589 1.0858 0.9507
L-Methionine S-oxide 1.2621 0.9199 0.8472
L-octanoylcarnitine (acyl-C8) 1.4578 1.0123 0.5808
L-Palmitoylcarnitine (acyl-C16) 1.1762 0.9704 0.8730
L-phenylalanine 0.8978 1.0946 0.9963
L-proline 1.0308 1.0452 0.9274
L-serine 1.0508 1.0644 0.8904
L-threonine 1.0765 1.0734 0.8586
L-tryptophan 0.8450 0.9682 1.1696
L-tyrosine 0.9665 1.0835 0.9462
L-valine 1.0779 1.2101 0.7207
N-Acetyl-L-citrulline 1.0831 1.5046 0.4215
N-Acetylornithine 1.2168 1.2372 0.5701
NAD+ 1.8984 0.1022 0.9995
NADP+ 1.3834 0.6964 0.9581
N-formyl kynurenine 1.0737 1.6926 0.2419
Nicotinamide 0.7153 1.0813 1.1717
N-Methylethanolamine phosphate 1.2601 1.2312 0.5376
Octadecanoyl-L-carnitine (acyl-C18) 1.0096 1.0449 0.9466
octenoyl-l-carnitine (acyl-C8:1) 0.8488 0.8335 1.3009
O-Decenoyl-L-carnitine (acyl-C10:1) 0.9303 0.6246 1.4373
O-dodecanoyl-carnitine (acyl-C12) 1.4794 0.9148 0.6590
O-dodecenoyl-carnitine (acyl-C12:1) 1.1035 1.4820 0.4260
O-octadecenoyl-L-carnitine (acyl-C18:1) 1.2650 0.9470 0.8174
Ornithine 1.0677 1.3015 0.6384
O-tetradecanoyl-L-carnitine (acyl-C14) 1.3512 0.8466 0.8413
Pantetheine 1.0557 1.5045 0.4460
Pantetheine 4--phosphate 0.8092 1.1232 1.0463
Phosphocreatine 0.8493 0.0766 1.8102
Phosphoserine 1.1530 1.0274 0.8367
Picolinic acid 0.8264 0.6243 1.5300
propionyl-carnitine (acyl-C3) 1.0623 1.0211 0.9235
Putrescine 1.1371 1.1180 0.7601
Pyridoxal 0.6532 1.4994 0.8088
Pyridoxamine 5^-phosphate 0.9124 0.8741 1.2038
(R)-S-Lactoylglutathione 1.4971 0.7682 0.7899
S-Adenosyl-L-homocysteine 1.0730 1.2727 0.6624
S-Adenosyl-L-methionine 1.0776 1.0856 0.8454
Serotonin 0.3816 0.6330 1.9167
S-Glutathionyl-L-cysteine 0.8357 1.0265 1.1195
Spermidine 1.1392 0.8358 1.0405
Spermine 0.3873 0.2866 2.2581
Sphingosine 0.6497 0.9264 1.3850
Tetradecenoyl Carnitine (acyl-C14:1) 1.1278 1.4161 0.4703
Thymine 1.1283 1.1411 0.7448
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Factors:

F1Genotype:Aged Berk
F2Genotype:Aged B-Thals
F3Genotype:WT (b-thal negative)
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