Data for (Study ST003550)
(Analysis AN005835)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| 2-OXOADIPIC ACID_13C1 | NA | 0.2027 | NA | NA | 0.1483 | 1.0302 | 1.7509 | 1.2447 |
| 2-OXOADIPIC ACID_13C2 | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| 2-OXOADIPIC ACID_13C3 | NA | 0.0644 | NA | 0.1616 | 0.9511 | 0.9350 | 1.2628 | 1.2707 |
| 2-OXOADIPIC ACID_13C4 | NA | NA | NA | NA | 0.8727 | 1.0424 | NA | NA |
| 2-OXOADIPIC ACID_13C5 | NA | NA | NA | NA | 1.0000 | NA | NA | NA |
| 2-OXOADIPIC ACID_13C6 | 0.5396 | NA | NA | NA | 1.1535 | NA | NA | NA |
| 2-OXOADIPIC ACID_M0 | 0.1535 | 0.6963 | 0.7809 | 0.9643 | 0.2311 | 1.3309 | 1.5830 | 1.5094 |
| ALPHA-KETOGLUTARIC ACID_13C1 | 2.0507 | 2.4758 | 2.0318 | 2.4569 | 0.0847 | 0.0970 | 0.0992 | 0.0923 |
| ALPHA-KETOGLUTARIC ACID_13C2 | 5.5548 | 1.8424 | 1.4551 | 1.7795 | 0.3444 | 0.0475 | 0.0539 | 0.0516 |
| ALPHA-KETOGLUTARIC ACID_13C3 | 0.5272 | 2.0323 | 0.6207 | 2.5199 | 0.2769 | 0.5407 | 0.6840 | 0.2302 |
| ALPHA-KETOGLUTARIC ACID_13C4 | NA | 1.6777 | NA | 1.6362 | 0.5797 | 0.6336 | 0.3645 | 0.6101 |
| ALPHA-KETOGLUTARIC ACID_13C5 | 0.0007 | 1.4483 | NA | 1.3066 | 0.6753 | 0.7870 | 0.6010 | 0.7600 |
| ALPHA-KETOGLUTARIC ACID_M0 | 2.0232 | 2.4692 | 2.0368 | 2.4621 | 0.0847 | 0.0994 | 0.1028 | 0.0953 |
| AMINOADIPATE_13C1 | NA | 0.0429 | 0.9459 | 0.7186 | 0.1598 | 0.6758 | 1.6885 | 1.5650 |
| AMINOADIPATE_13C2 | NA | 2.3603 | NA | 2.3906 | 0.0044 | 0.0230 | 0.0416 | 0.0310 |
| AMINOADIPATE_13C3 | NA | 0.9968 | NA | 1.0032 | NA | NA | NA | NA |
| AMINOADIPATE_13C4 | NA | NA | NA | NA | 1.2050 | 0.7983 | NA | 0.5800 |
| AMINOADIPATE_13C5 | 1.4326 | 0.8017 | NA | 0.7107 | 2.3403 | 0.2922 | 0.1893 | 0.3478 |
| AMINOADIPATE_13C6 | 0.7925 | NA | NA | NA | 1.0692 | NA | NA | NA |
| AMINOADIPATE_15N1 | NA | 1.3031 | NA | NA | 0.0007 | 1.7828 | 0.0252 | 0.0249 |
| AMINOADIPATE_M0 | 0.0352 | 0.1799 | 1.2518 | 0.8995 | 0.1215 | 0.9065 | 2.1086 | 2.0216 |
| CITRATE_13C1 | 1.4522 | 1.4983 | 1.4237 | 1.4952 | 0.6377 | 0.6706 | 0.7218 | 0.6844 |
| CITRATE_13C2 | 5.3439 | 0.9978 | 0.9562 | 0.9825 | 1.1556 | 0.4594 | 0.4974 | 0.4739 |
| CITRATE_13C3 | 6.3253 | 0.1456 | 0.1091 | 0.1493 | 1.1072 | 0.0463 | 0.1041 | 0.1701 |
| CITRATE_13C4 | NA | NA | NA | NA | 1.0000 | NA | NA | NA |
| CITRATE_13C5 | NA | NA | 1.0000 | NA | NA | NA | NA | NA |
| CITRATE_13C6 | NA | NA | 0.7240 | 1.0849 | NA | NA | 1.1911 | NA |
| CITRATE_M0 | 1.4303 | 1.5053 | 1.4232 | 1.4988 | 0.6340 | 0.6687 | 0.7223 | 0.6865 |
| FUMARATE_13C1 | 2.2374 | 2.0862 | 2.2675 | 2.0022 | 0.2533 | 0.2812 | 0.2806 | 0.2616 |
| FUMARATE_13C2 | 6.8112 | 0.4100 | 0.7038 | 0.2882 | 0.8416 | 0.0634 | 0.0580 | 0.0702 |
| FUMARATE_13C3 | 1.6319 | 0.9969 | 1.8565 | 1.0037 | 0.7568 | 0.9321 | 0.9706 | 0.8435 |
| FUMARATE_13C4 | 0.3777 | 1.6247 | 0.4172 | 0.8035 | 1.0621 | 0.9727 | 0.8807 | 1.0695 |
| FUMARATE_M0 | 2.2252 | 2.1012 | 2.2259 | 2.0213 | 0.2445 | 0.2821 | 0.2750 | 0.2588 |
| GLUTAMATE_13C1 | 1.6551 | 2.3234 | 1.6485 | 2.3002 | 0.2303 | 0.2402 | 0.2456 | 0.2257 |
| GLUTAMATE_13C2 | 4.6824 | 1.7167 | 1.1373 | 1.6788 | 0.8977 | 0.1452 | 0.1457 | 0.1426 |
| GLUTAMATE_13C3 | 1.7159 | 0.2645 | NA | NA | 0.5293 | NA | NA | NA |
| GLUTAMATE_13C4 | NA | 0.6320 | NA | NA | NA | 1.1850 | 1.1117 | 0.4782 |
| GLUTAMATE_13C5 | NA | 0.4090 | NA | 0.1367 | 0.7450 | 1.9614 | 2.8831 | 1.0836 |
| GLUTAMATE_15N1 | 0.5337 | 2.4841 | 1.0223 | 1.6645 | 0.2712 | 0.6351 | 0.8042 | 0.2888 |
| GLUTAMATE_M0 | 1.6294 | 2.3263 | 1.6545 | 2.2993 | 0.2264 | 0.2424 | 0.2479 | 0.2298 |
| L-CARNITINE_13C1 | 2.4965 | 2.4507 | 2.3635 | 2.4837 | 0.0201 | 0.0239 | 0.0335 | 0.0347 |
| L-CARNITINE_13C2 | 1.2589 | 1.2808 | 1.2372 | 1.3267 | 0.0056 | 0.0058 | 0.0048 | 0.0071 |
| L-CARNITINE_13C3 | 0.8201 | 1.1354 | NA | 1.2472 | NA | 0.6619 | NA | NA |
| L-CARNITINE_13C4 | NA | NA | NA | NA | NA | NA | NA | NA |
| L-CARNITINE_13C5 | NA | NA | NA | NA | 1.0000 | NA | NA | NA |
| L-CARNITINE_13C6 | NA | NA | NA | NA | NA | NA | NA | NA |
| L-CARNITINE_13C7 | NA | NA | NA | NA | NA | NA | NA | NA |
| L-CARNITINE_15N | 1.6323 | 1.6556 | 1.6172 | 1.6916 | 0.0045 | 0.0052 | 0.0109 | 0.0083 |
| L-CARNITINE_M0 | 2.5214 | 2.4378 | 2.3734 | 2.4781 | 0.0219 | 0.0261 | 0.0348 | 0.0363 |
| LYSINE_M0 | 0.0991 | 0.2674 | 0.1050 | 4.4381 | 0.0765 | 0.0818 | 0.1036 | 1.6313 |
| LYSINE_M1_13C1 | 0.0890 | 0.0012 | NA | 3.8212 | 0.0694 | 0.0030 | 0.0020 | 1.4089 |
| LYSINE_M1_13C2 | NA | NA | NA | 2.1285 | 0.0067 | 0.0025 | NA | 0.7558 |
| LYSINE_M1_13C3 | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| LYSINE_M1_13C4 | 1.9235 | NA | NA | NA | 0.8027 | NA | NA | 0.0051 |
| LYSINE_M1_13C5 | 3.8080 | 0.0018 | 0.0016 | 0.0005 | 1.7215 | 0.0058 | 0.0141 | 0.0121 |
| LYSINE_M1_13C6 | 4.0787 | 0.0005 | 0.0006 | 0.0008 | 1.8616 | 0.0002 | 0.0003 | 0.0008 |
| LYSINE_M1_15N1 | 0.0013 | 3.2102 | 2.5625 | 0.0249 | 0.0015 | 1.1666 | 1.3996 | 0.0094 |
| LYSINE_M1_15N2 | NA | 1.8086 | 1.3965 | 0.0044 | 0.0009 | 0.6402 | 0.7518 | 0.0008 |
| MALATE_13C1 | 2.1034 | 2.1176 | 2.0223 | 2.0698 | 0.2614 | 0.2928 | 0.2837 | 0.2661 |
| MALATE_13C2 | 6.1860 | 1.4053 | 1.3049 | 1.3996 | 0.8266 | 0.1937 | 0.1780 | 0.1665 |
| MALATE_13C3 | 0.4852 | 1.5446 | NA | 0.9335 | 0.4487 | 0.0343 | NA | NA |
| MALATE_13C4 | NA | 2.7150 | NA | 1.1134 | 0.0973 | 0.0843 | 0.0743 | 0.0871 |
| MALATE_M0 | 2.0627 | 2.1205 | 2.0329 | 2.0782 | 0.2558 | 0.2933 | 0.2859 | 0.2678 |
| N-EPSILON-ACETYLLYSINE_13C1 | NA | 0.3451 | NA | 1.6179 | NA | 0.0236 | NA | NA |
| N-EPSILON-ACETYLLYSINE_13C2 | 1.3693 | NA | NA | NA | NA | NA | NA | 0.6307 |
| N-EPSILON-ACETYLLYSINE_13C3 | NA | NA | NA | NA | NA | NA | NA | NA |
| N-EPSILON-ACETYLLYSINE_13C4 | NA | NA | NA | NA | NA | NA | NA | NA |
| N-EPSILON-ACETYLLYSINE_13C5 | 1.2516 | NA | NA | NA | 0.2453 | NA | NA | NA |
| N-EPSILON-ACETYLLYSINE_13C6 | 3.3649 | NA | NA | NA | 0.2117 | NA | NA | NA |
| N-EPSILON-ACETYLLYSINE_13C7 | NA | NA | NA | NA | NA | NA | NA | NA |
| N-EPSILON-ACETYLLYSINE_13C8 | NA | NA | NA | NA | NA | NA | NA | NA |
| N-EPSILON-ACETYLLYSINE_15N1 | NA | 2.7242 | 1.1668 | NA | NA | 0.1040 | 0.1162 | NA |
| N-EPSILON-ACETYLLYSINE_15N2 | NA | 1.0512 | 0.9281 | 1.0203 | NA | 1.0003 | NA | NA |
| N-EPSILON-ACETYLLYSINE_M0 | 0.2858 | 1.3509 | 0.2380 | 4.9253 | 0.0208 | 0.0124 | 0.0213 | 0.1616 |
| N,N,N-TRIMETHYLLYSINE_13C1 | 0.5477 | 1.0478 | 0.0265 | 2.7680 | 0.0673 | 0.0523 | 0.0548 | 0.1149 |
| N,N,N-TRIMETHYLLYSINE_13C2 | 0.4191 | 1.1115 | 0.2254 | 2.5062 | 0.0558 | 0.0304 | 0.0247 | 0.0667 |
| N,N,N-TRIMETHYLLYSINE_13C3 | NA | NA | NA | 1.2881 | 1.2085 | 0.5034 | NA | NA |
| N,N,N-TRIMETHYLLYSINE_13C4 | 1.0000 | NA | NA | NA | NA | NA | NA | NA |
| N,N,N-TRIMETHYLLYSINE_13C5 | 3.5277 | NA | NA | NA | 0.1001 | 0.0041 | 0.0045 | 0.0038 |
| N,N,N-TRIMETHYLLYSINE_13C6 | 2.2180 | NA | NA | NA | 0.0865 | NA | NA | NA |
| N,N,N-TRIMETHYLLYSINE_13C7 | 4.7465 | 0.0268 | NA | 0.0367 | 0.1241 | NA | NA | NA |
| N,N,N-TRIMETHYLLYSINE_13C8 | NA | NA | NA | NA | NA | NA | NA | NA |
| N,N,N-TRIMETHYLLYSINE_13C9 | NA | NA | NA | NA | NA | NA | NA | NA |
| N,N,N-TRIMETHYLLYSINE_15N1 | 0.0070 | 4.1509 | 3.0174 | 0.0558 | 0.0014 | 0.0552 | 0.1101 | 0.0022 |
| N,N,N-TRIMETHYLLYSINE_15N2 | 0.0241 | 1.6435 | 1.0308 | NA | NA | NA | 0.0181 | 0.0158 |
| N,N,N-TRIMETHYLLYSINE_M0 | 0.5360 | 1.4164 | 0.5076 | 2.6839 | 0.0465 | 0.0405 | 0.0447 | 0.1155 |
| O-ACETYLCARNITINE_13C1 | 2.5935 | 2.3327 | 2.7184 | 2.2903 | 0.0613 | 0.0707 | 0.0693 | 0.0718 |
| O-ACETYLCARNITINE_13C2 | 5.8664 | 1.8334 | 2.2235 | 1.8151 | 0.2119 | 0.0337 | 0.0410 | 0.0349 |
| O-ACETYLCARNITINE_13C3 | 3.3280 | 0.2524 | 0.1342 | 0.2334 | 0.2192 | NA | NA | NA |
| O-ACETYLCARNITINE_13C4 | NA | NA | 2.1333 | NA | 0.5314 | 0.8038 | NA | NA |
| O-ACETYLCARNITINE_13C5 | NA | 1.3552 | NA | 1.2399 | NA | 0.0640 | NA | 0.1506 |
| O-ACETYLCARNITINE_13C6 | NA | NA | NA | NA | NA | NA | 1.0000 | NA |
| O-ACETYLCARNITINE_13C7 | NA | NA | NA | NA | 0.6982 | NA | NA | 1.1509 |
| O-ACETYLCARNITINE_13C8 | NA | 1.5734 | NA | 1.9054 | 0.6320 | 0.8310 | 0.4848 | 1.3873 |
| O-ACETYLCARNITINE_13C9 | NA | NA | NA | NA | NA | NA | NA | NA |
| O-ACETYLCARNITINE_M0 | 2.5916 | 2.3333 | 2.7165 | 2.2884 | 0.0625 | 0.0718 | 0.0690 | 0.0723 |
| PIPECOLATE_13C1 | 0.0819 | 0.2556 | 0.0793 | 2.7243 | 0.2731 | 0.2750 | 1.3009 | 1.5633 |
| PIPECOLATE_13C2 | NA | NA | NA | NA | NA | NA | NA | NA |
| PIPECOLATE_13C3 | 0.5514 | 3.5383 | 0.1255 | 1.7078 | 0.5954 | 0.7608 | 0.4158 | 0.4276 |
| PIPECOLATE_13C4 | NA | 1.6601 | NA | NA | NA | NA | 0.3399 | NA |
| PIPECOLATE_13C5 | NA | 1.2745 | NA | 1.4382 | 1.1270 | 0.2220 | 0.1497 | 0.1831 |
| PIPECOLATE_13C6 | 0.1057 | 0.0129 | 0.0188 | 0.0067 | 2.7276 | 0.0062 | 0.0097 | 0.0181 |
| PIPECOLATE_15N1 | NA | 3.8129 | NA | 0.0918 | 0.0045 | 0.9400 | 0.0475 | 0.0102 |
| PIPECOLATE_M0 | 0.2102 | 0.4342 | 0.1490 | 4.4919 | 0.1614 | 0.2143 | 1.0786 | 1.0293 |
| PIPERIDINE 6-CARBOXYLATE (P6C / P2C)_13C1 | 0.0332 | 0.0331 | 0.2254 | 0.1317 | 0.0847 | 0.0677 | 3.2093 | 2.5648 |
| PIPERIDINE 6-CARBOXYLATE (P6C / P2C)_13C2 | 0.0442 | NA | NA | NA | NA | NA | 1.1044 | 1.1346 |
| PIPERIDINE 6-CARBOXYLATE (P6C / P2C)_13C3 | 1.1853 | 0.3970 | 0.8221 | 0.2763 | 1.0642 | 1.3723 | 1.5014 | 1.3364 |
| PIPERIDINE 6-CARBOXYLATE (P6C / P2C)_13C4 | 2.4787 | 1.1188 | 1.3375 | 2.0978 | 0.5366 | 0.6585 | 0.6463 | 0.5136 |
| PIPERIDINE 6-CARBOXYLATE (P6C / P2C)_13C5 | 0.0608 | 0.0017 | 0.0033 | NA | 2.6333 | 0.0011 | 0.0018 | 0.0050 |
| PIPERIDINE 6-CARBOXYLATE (P6C / P2C)_13C6 | 0.3288 | NA | NA | 0.0037 | 2.3768 | 0.1829 | 0.1295 | 0.1829 |
| PIPERIDINE 6-CARBOXYLATE (P6C / P2C)_15N1 | 0.0053 | 0.5066 | 0.0090 | 0.0103 | 0.0041 | 5.1757 | 0.0167 | 0.0124 |
| PIPERIDINE 6-CARBOXYLATE (P6C / P2C)_M0 | 0.0936 | 0.0573 | 0.4787 | 0.2169 | 0.1759 | 0.1813 | 3.0086 | 2.7312 |
| SACCHAROPINE_13C1 | 0.0683 | 0.0012 | 0.1187 | 4.8646 | 0.0175 | 0.0005 | 0.0272 | 0.1410 |
| SACCHAROPINE_13C10 | NA | NA | NA | NA | NA | 1.4786 | 0.5214 | NA |
| SACCHAROPINE_13C11 | NA | NA | NA | NA | NA | NA | NA | NA |
| SACCHAROPINE_13C2 | NA | 0.0257 | 0.0229 | 2.6289 | NA | 0.0168 | 0.0188 | 0.0326 |
| SACCHAROPINE_13C3 | NA | NA | NA | 1.4003 | NA | 0.1706 | NA | 0.2281 |
| SACCHAROPINE_13C4 | 1.3602 | NA | NA | NA | 1.0029 | 0.2768 | NA | NA |
| SACCHAROPINE_13C5 | 4.0067 | 0.6513 | NA | 0.5457 | 0.9748 | 0.0066 | 0.0059 | NA |
| SACCHAROPINE_13C6 | 4.2609 | 0.0009 | NA | NA | 1.0233 | 0.0003 | 0.0017 | 0.0005 |
| SACCHAROPINE_13C7 | 3.8507 | 0.0163 | NA | 0.0105 | 0.9330 | 0.0049 | 0.0033 | 0.0041 |
| SACCHAROPINE_13C8 | 3.0539 | 0.3942 | NA | NA | 1.4369 | 0.1611 | 0.1517 | NA |
| SACCHAROPINE_13C9 | NA | NA | NA | NA | NA | NA | NA | NA |
| SACCHAROPINE_15N1 | 0.0001 | 5.1760 | 0.4984 | 0.0345 | 0.0001 | 0.1500 | 0.1392 | 0.0009 |
| SACCHAROPINE_15N2 | 0.0868 | 2.2572 | 0.7331 | 0.1486 | NA | 0.5178 | 0.2850 | NA |
| SACCHAROPINE_M0 | 0.0795 | 0.8386 | 0.1874 | 5.4818 | 0.0193 | 0.0216 | 0.0537 | 0.1627 |
| SUCCINATE_13C1 | 1.8959 | 2.2469 | 1.7419 | 2.2096 | 0.2211 | 0.2297 | 0.2367 | 0.3101 |
| SUCCINATE_13C2 | 4.2817 | 0.6117 | 0.2527 | 0.7102 | 0.2999 | 0.1761 | NA | 0.0550 |
| SUCCINATE_13C3 | NA | 1.6513 | NA | 2.9313 | 0.3758 | 0.2900 | NA | NA |
| SUCCINATE_13C4 | NA | 0.4220 | 0.3755 | 0.8998 | 1.7423 | 0.9228 | 0.7893 | 1.9820 |
| SUCCINATE_M0 | 1.7645 | 2.3263 | 1.6696 | 2.3333 | 0.1839 | 0.1919 | 0.2050 | 0.2815 |
Factors:
| F1 | Sample source:HEK293 | Isotope Tracer:13C6-L-lysine |
| F2 | Sample source:HEK293 | Isotope Tracer:alpha-15N-L-lysine |
| F3 | Sample source:HEK293 | Isotope Tracer:epsilon-15N-L-lysine |
| F4 | Sample source:HEK293 | Isotope Tracer:unlabeled L-lysine |
| F5 | Sample source:Primary mouse astrocytes | Isotope Tracer:13C6-L-lysine |
| F6 | Sample source:Primary mouse astrocytes | Isotope Tracer:alpha-15N-L-lysine |
| F7 | Sample source:Primary mouse astrocytes | Isotope Tracer:epsilon-15N-L-lysine |
| F8 | Sample source:Primary mouse astrocytes | Isotope Tracer:unlabeled L-lysine |
